Tacrolimus and condition aggravated Patient Reports February 12, 2012

Tacrolimus Side Effects Report #5506381-X
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 19, 2007. Male patient, 77 years of age, weighting 143.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, infection , interstitial lung disease. Tacrolimus dosage: 1.5 MG, /D, ORAL; 2 MG, /D, ORAL; 3 MG, /D, ORAL. During the same period patient was treated with PREDNISONE, SIGMART, ASPIRIN, CARVEDILOL, CANDESARTAN CILEXETIL, MAGLAX. Patient died on 07/15/2006.

Tacrolimus Side Effects Report #5584753-5
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 21, 2007. Male patient, 77 years of age, weighting 143.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: arrhythmia , blood beta-d-glucan increased, blood pressure decreased, bradycardia, cell marker increased, condition aggravated, disseminated intravascular coagulation, hyperkalaemia, interstitial lung disease. Tacrolimus dosage: 1.5 MG, UID/QD, ORAL; 2MG, UID/QD; ORAL, 3MG, UID/QD; ORAL. During the same period patient was treated with PREDNISOLONE, SIGMART, BAYASPIRINLET, CARVEDILOL, BLOPRESS, MAGLAX. Patient died on 07/15/2006.

Tacrolimus Side Effects Report #5629992-X
Tacrolimus side effect was reported by a Physician from JAPAN on Jan 28, 2008. Male patient, 77 years of age, weighting 143.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: arrhythmia , aspiration bone marrow abnormal, blood pressure decreased, bradycardia, condition aggravated, disseminated intravascular coagulation, hyperkalaemia, interstitial lung disease, pancytopenia. Tacrolimus dosage: 1.5 MG, UID/QD, ORAL; 2 MG, UID/QD, ORAL; 3 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, SIGMART, BAYASPIRINLET, CARVEDILOL, BLOPRESS. Patient died on 07/15/2006.

Tacrolimus Side Effects Report #5584752-3
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 20, 2007. Male patient, 76 years of age, weighting 154.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, glucose tolerance impaired. Tacrolimus dosage: 1.5 MG, UI/QD, ORAL. During the same period patient was treated with PREDNISOLONE, LOXONIN, BONALON, ACTOS, OMEPRALLET, BAKTAR, MUCOSTA, DIART. Patient recovered.


Tacrolimus Side Effects Report #5451900-5
Tacrolimus side effect was reported by a Physician from JAPAN on Aug 29, 2007. Female patient, 75 years of age, weighting 100.8 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, constipation , glycosylated haemoglobin increased, rheumatoid arthritis , white blood cell count increased. Tacrolimus dosage: 0.5 MG, D, ORAL; 1 MG, D, ORAL. During the same period patient was treated with PREDNISONE, BUCILLAMINE, BENET, MINOCYCLINE HYDROCHLORIDE, ISALON, MUCOSTA, CEROCRAL. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5705345-0
Tacrolimus side effect was reported by a Physician from JAPAN on Mar 25, 2008. Female patient, 75 years of age, weighting 100.8 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, constipation , glycosylated haemoglobin increased, rheumatoid arthritis , white blood cell count increased. Tacrolimus dosage: 0.5 MG, /D, ORAL; 1MG,/D, ORAL. During the same period patient was treated with PREDNISOLONE, BUCILLAMINE, RISEDRONATE, MINOCYCLINE HYDROCHLORIDE, ISALON, MUCOSTA, CEROCRAL. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5721413-1
Tacrolimus side effect was reported by a Physician from JAPAN on Apr 11, 2008. Female patient, 75 years of age, weighting 100.8 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, constipation , glycosylated haemoglobin increased, rheumatoid arthritis , white blood cell count increased. Tacrolimus dosage: 0.5 MG, /D, ORAL; 1 MG, /D, ORAL. During the same period patient was treated with PREDNISOLONE, BUCILLAMINE, RISEDRONATE, MINOCYMIN, ISALON, MUCOSTA, CEROCRAL. Patient recovered.

Tacrolimus Side Effects Report #5266625-9
Tacrolimus side effect was reported by a Physician from JAPAN on Feb 27, 2007. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, condition aggravated, diffuse alveolar damage, fungal infection , heart rate increased, interstitial lung disease, lung disorder, no therapeutic response, pneumocystis jiroveci infection. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, METALCAPTASE CAPSULE, PREDNISOLONE, LOXONIN, CLINORIL, MUCOSTA, AMARYL. Patient died on 08/13/2006.

Tacrolimus Side Effects Report #5104069-0
Tacrolimus side effect was reported by a Physician from JAPAN on Sept 04, 2006. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, condition aggravated, interstitial lung disease, lower respiratory tract infection bacterial, lower respiratory tract infection fungal, lung disorder, pneumocystis jiroveci infection, pulmonary tuberculosis. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, METALCAPTASE CAPSULE, PREDNISOLONE, LOXONIN, CLINORIL, MUCOSTA, AMARYL. Patient died on 08/13/2006.


Tacrolimus Side Effects Report #5170649-X
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 16, 2006. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, renal tubular disorder. Tacrolimus dosage: unknown. During the same period patient was treated with METALCAPTASE, PREDNISOLONE, LOXONIN, CLINORIL, MUCOSTA, AMARYL. Patient died on 08/13/2006.

Tacrolimus Side Effects Report #5679811-0
Tacrolimus side effect was reported by a Physician from JAPAN on Mar 05, 2008. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, condition aggravated, heart rate increased, interstitial lung disease, lung disorder, no therapeutic response, pyrexia, renal tubular disorder. Tacrolimus dosage: 1 MG, UID/QD, ORAL; 2 MG, UID/QD, ORAL. During the same period patient was treated with METALCAPTASE CAPSULE, PREDNISOLONE, LOXONIN, CLINORIL, MUCOSTA, AMARYL. Patient died on 08/13/2006.

Tacrolimus Side Effects Report #5936053-9
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 16, 2008. Male patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetic nephropathy, disease progression, renal failure chronic, shock. Tacrolimus dosage: 1.5 MG/D, ORAL. During the same period patient was treated with BASEN, KINEDAK, AMARYL, FUROSEMIDE, SALOBELLET, PREDNISOLONE, LOXONIN. Patient died on 02/10/2007.

Tacrolimus Side Effects Report #5088352-3
Tacrolimus side effect was reported by a Physician from JAPAN on Aug 10, 2006. Female patient, 72 years of age, weighting 111.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, dyskinesia, fall , fracture , haemorrhage, platelet count decreased, tremor. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, LOXOPROFEN, VOLTAREN. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5117973-4
Tacrolimus side effect was reported by a Physician from JAPAN on Sept 12, 2006. Female patient, 72 years of age, weighting 111.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, dyskinesia, fall , fracture , haemorrhage, platelet count decreased, tremor. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, LOXOPROFEN, VOLTAREN. Patient was hospitalized. Patient recovered.


Tacrolimus Side Effects Report #5170329-0
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 21, 2006. Female patient, 72 years of age, weighting 107.6 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bacteria sputum identified, beta 2 microglobulin urine increased, blood pressure decreased, cardiac arrest , chlamydial infection, cholecystitis, condition aggravated, cytomegalovirus infection , disseminated intravascular coagulation. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE. Patient was hospitalized. Patient died on 10/28/2006.

Tacrolimus Side Effects Report #4971323-2
Tacrolimus side effect was reported by a Consumer or non-health professional from JAPAN on Mar 27, 2006. Male patient, 70 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: amyotrophic lateral sclerosis , condition aggravated, respiratory paralysis. Tacrolimus dosage: 3 MG,/D. During the same period patient was treated with PREDNISOLONE, RIMATIL. Patient died on 03/27/2006.

Tacrolimus Side Effects Report #4978841-1
Tacrolimus side effect was reported by a Physician from JAPAN on Apr 05, 2006. Male patient, 70 years of age, weighting 121.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: amyotrophic lateral sclerosis , arrhythmia , condition aggravated, muscular weakness, pneumonia , respiratory paralysis, supraventricular tachycardia, yellow nail syndrome. Tacrolimus dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with RIMATIL, VASOLAN, PREDNISOLONE, LOXONIN, MAGMITT, CLARITHROMYCIN. Patient died on 03/27/2006.

Tacrolimus Side Effects Report #5006791-3
Tacrolimus side effect was reported by a Physician from JAPAN on May 08, 2006. Male patient, 70 years of age, weighting 121.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: amyotrophic lateral sclerosis , arrhythmia , condition aggravated, neutrophil count increased, pneumonia , respiratory paralysis, supraventricular tachycardia, yellow nail syndrome. Tacrolimus dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with RIMATIL, PREDNISOLONE, LOXONIN, MAGMITT, CLARITHROMYCIN, VASOLAN. Patient died on 03/27/2006.

Tacrolimus Side Effects Report #5314201-1
Tacrolimus side effect was reported by a Physician from JAPAN on Apr 09, 2007. Male patient, 69 years of age, weighting 104.7 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: beta 2 microglobulin increased, blood urea increased, condition aggravated, diabetes mellitus, extremity necrosis, skin ulcer. Tacrolimus dosage: unknown. During the same period patient was treated with PREDNISOLONE, TAMSULOSIN, LIPITOR, MOBIC, ASPIRIN, DIOVAN. Patient was hospitalized and became disabled. Patient recovered.


Tacrolimus Side Effects Report #5536715-1
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 19, 2007. Female patient, 69 years of age, weighting 100.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease. Tacrolimus dosage: 1.5 MG, D, ORAL. During the same period patient was treated with PREDNISONE, SOL MEDROL, METHYCOBAL, DEPAS, MUCOSTA, MEXITIL, MAGNESIUM OXIDE, JUVELA. Patient died on 07/01/2007.

Tacrolimus Side Effects Report #5622123-1
Tacrolimus side effect was reported by a Physician from JAPAN on Jan 22, 2008. Female patient, 69 years of age, weighting 100.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease. Tacrolimus dosage: 1.5 MG, /D, ORAL. During the same period patient was treated with PREDNISOLONE, SOL MEDROL, METHYCOBAL, DEPAS, MUCOSTA, MEXITIL, MAGNESIUM OXIDE, JUVELA. Patient died on 07/01/2007.

Tacrolimus Side Effects Report #5661621-1
Tacrolimus side effect was reported by a Physician from JAPAN on Feb 19, 2008. Female patient, 69 years of age, weighting 100.3 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease. Tacrolimus dosage: unknown. During the same period patient was treated with PREDNISOLONE, SOL MEDROL, METHYCOBAL, DEPAS, MUCOSTA, MEXITIL, MAGNESIUM OXIDE, JUVELA. Patient died on 07/01/2007.

Tacrolimus Side Effects Report #5584784-5
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 25, 2007. Female patient, 66 years of age, weighting 108.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: beta-n-acetyl-d-glucosaminidase increased, condition aggravated, hepatitis b , hepatorenal syndrome, lymphocyte count decreased. Tacrolimus dosage: 1.5 MG, UID/QD; ORAL, 3MG, UID/QD; ORAL,. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, ENBREL, ETODOLAC, VOLTAREN, ISCOTIN. Patient died on 05/03/2007.

Tacrolimus Side Effects Report #5622133-4
Tacrolimus side effect was reported by a Physician from JAPAN on Jan 22, 2008. Female patient, 66 years of age, weighting 108.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: beta-n-acetyl-d-glucosaminidase increased, condition aggravated, hepatitis b , hepatorenal syndrome, lymphocyte count decreased. Tacrolimus dosage: 1.5 MG, UID/QD, ORAL; 3 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, ENBREL, ETODOLAC, VOLTAREN, ISCOTIN. Patient died on 05/03/2007.


Tacrolimus Side Effects Report #5638752-5
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 05, 2007. Female patient, 66 years of age, weighting 108.0 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: ammonia increased, beta-n-acetyl-d-glucosaminidase increased, condition aggravated, dyspnoea, hepatitis b , hepatorenal syndrome, lymphocyte count decreased, oedema, oedema peripheral. Tacrolimus dosage: 1.5 MG, UID/QD; ORAL, 3 MG, UID/QD; ORAL. During the same period patient was treated with PREDNONINE, METHOTREXATE, ENBREL, ETODOLAC, VOLTAREN, ISCOTIN. Patient died on 05/03/2007.

Tacrolimus Side Effects Report #5070376-3
Tacrolimus side effect was reported by a Physician from JAPAN on July 18, 2006. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, immunosuppression, interstitial lung disease, pneumocystis jiroveci pneumonia, respiratory failure. Tacrolimus dosage: 2 MG ORAL. During the same period patient was treated with PREDNISOLONE, GASTER, MOBIC, NORVASC, LOXONIN, LIPITOR, OMEPRAZOLE, PROMAC. Patient died on 07/05/2006.

Tacrolimus Side Effects Report #5079951-3
Tacrolimus side effect was reported by a Physician from JAPAN on July 27, 2006. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, pneumocystis jiroveci pneumonia, respiratory failure. Tacrolimus dosage: 2 MG, D, ORAL; 3 MG, D, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE, GASTER, MOBIC, NORVASC, LOXONIN, LIPITOR, OMEPRAZOLE. Patient died on 07/05/2006.

Tacrolimus Side Effects Report #5145633-2
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 23, 2006. Female patient, 64 years of age, weighting 81.57 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: arthralgia, atrial thrombosis, condition aggravated, dyspnoea, eosinophil count increased, haemorrhagic cerebral infarction, hemiplegia, loss of consciousness, lung disorder. Tacrolimus dosage: 1.5 MG, D, ORAL; 2 MG, D, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE, AZULFIDINE, MOBIC, VOLTAREN, ALFAROL, WARFARIN. Patient was hospitalized. Patient died on 08/23/2006.

Tacrolimus Side Effects Report #5193210-X
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 16, 2006. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bacterial infection , blood beta-d-glucan increased, cell marker increased, chest x-ray abnormal, computerised tomogram abnormal, computerised tomogram thorax, condition aggravated, cytomegalovirus antigen positive, interstitial lung disease. Tacrolimus dosage: 2 MG, ORAL; SEE IMAGE. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE, GASTER, MOBIC, NORVASC, LOXONIN, LIPITOR, OMEPRAZON. Patient died on 07/05/2006.


Tacrolimus Side Effects Report #4830958-8
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 02, 2005. Female patient, 59 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: amyloidosis, condition aggravated, pulmonary embolism , vomiting. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISONE, METHYLPREDNISOLONE, VOLTAREN, DOGMATYL, TOLEDOMIN, RABEPRAZOLE, LUPRAC. Patient died on 08/19/2005.

Tacrolimus Side Effects Report #4852960-2
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 30, 2005. Female patient, 59 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: amyloidosis, condition aggravated, pulmonary embolism , vomiting. Tacrolimus dosage: 1.50 MG, D, ORAL; 3 MG, D, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISONE, METHYLPREDNISOLONE, VOLTAREN, DOGMATYL, TOLEDOMIN, RABEPRAZOLE, LUPRAC. Patient died on 08/19/2005.

Tacrolimus Side Effects Report #5515840-5
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 29, 2007. Male patient, 58 years of age, weighting 180.8 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood glucose increased, condition aggravated, glucose tolerance impaired, glycosylated haemoglobin increased. Tacrolimus dosage: 2 MG, D, ORAL, 3 MG, D, ORAL. During the same period patient was treated with PREDNISONE, RHEUMATREX, RIMATIL, VOLTAREN SLOW RELEASE CAPSULES, MUCOSTA, LANSOPRAZOLE. Patient recovered.

Tacrolimus Side Effects Report #4983561-3
Tacrolimus side effect was reported by a Physician from JAPAN on Apr 06, 2006. Male patient, 57 years of age, weighting 123.5 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood glucose increased, condition aggravated, diabetes mellitus inadequate control, glucose urine present, hepatic function abnormal, interstitial lung disease, liver disorder. Tacrolimus dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, LOXONIN, RHEUMATREX. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5054131-6
Tacrolimus side effect was reported by a Physician from JAPAN on June 29, 2006. Female patient, 25 years of age, weighting 72.75 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, depression , mental disorder, persecutory delusion, suicide attempt, vomiting. Tacrolimus dosage: 1 MG, UID/QD, ORAL; 2 MG UID/QD, ORAL; 54 DF D, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, RHEUMATREX, VOLTAREN, LENDORMIN, PREDNISOLONE, RIMATIL. Patient was hospitalized. Patient recovered.


Tacrolimus Side Effects Report #5207358-4
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 26, 2006. Male patient was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood amylase increased, condition aggravated, haematocrit decreased, haemoglobin decreased, interstitial lung disease, lymphocyte count decreased, neurogenic bladder, red blood cell count decreased, rheumatoid arthritis . Tacrolimus dosage: 1 MG, UID/QD, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE, ENBREL, MINOCYCLINE HYDROCHLORIDE, PLETAL, LANSOPRAZOLE, RHEUMATREX, NEO MINOPHAGEN C. Patient died on 11/05/2006.

Tacrolimus Side Effects Report #5193269-X
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 07, 2006. Male patient was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, spinal cord infarction. Tacrolimus dosage: 1 MG, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE, ENBREL, RHEUMATREX, NEO MINOPHAGEN C. Patient was hospitalized. Patient died on 11/05/2006.

Tacrolimus Side Effects Report #5451882-6
Tacrolimus side effect was reported by a Physician from JAPAN on Aug 27, 2007. Male patient was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, lung neoplasm malignant. Tacrolimus dosage: 1 MG, UID/QD, ORAL, 1.5 MG, UID/QD, ORAL, 2 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, RELIFEN, RISEDRONATE, LIVALO, AMLODIPINE BESYLATE. Patient died on 01/23/2007.

Tacrolimus Side Effects Report #5472523-8
Tacrolimus side effect was reported by a Physician from JAPAN on Sept 14, 2007. Male patient was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: abasia, condition aggravated, diabetes mellitus, hyperlipidaemia, hypertension, interstitial lung disease, lung neoplasm malignant, metastases to bone, osteoporosis . Tacrolimus dosage: 1 MG, UID/QD, ORAL, 1.5 MG, UID/QD, ORAL, 2 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, RELIFEN, RISEDRONATE, LIVALO, AMLODIPINE BESYLATE. Patient died on 01/23/2007.

Tacrolimus Side Effects Report #5492875-2
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 07, 2007. Male patient was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: abasia, bladder disorder, condition aggravated, gastrointestinal disorder, lung neoplasm malignant, metastases to bone, pneumonia , restlessness, spinal compression fracture. Tacrolimus dosage: 1 MG, UID/QD, ORAL; 1.5 MG, UID/QD, ORAL; 2 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, RELIFEN, RISEDRONATE, LIVALO, AMLODIPINE BESYLATE, MARZULENE S. Patient died on 01/23/2007.


Tacrolimus Side Effects Report #5871164-8
Tacrolimus side effect was reported by a Health Professional from UNITED STATES on Aug 19, 2008. Male patient, 68 years of age, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: cardiac failure, condition aggravated, deafness, dysuria, effusion, haematuria, nephropathy toxic, pollakiuria, pulmonary hypertension . Tacrolimus dosage: 0.75 MG, UID/QD,ORAL. During the same period patient was treated with CELLCEPT, PREDNISOLONE ACETATE, CARDURA, COREG, METOPROLOL SUCCINATE, MINOXIDIL, NORVASC, PRAVACHOL. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4983545-5
Tacrolimus side effect was reported by a Physician from GERMANY on Apr 03, 2006. Male patient, child 4 years of age, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, intracranial pressure increased, optic atrophy, optic neuropathy. Tacrolimus dosage: 2.5 MG, D, ORAL; 1 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, MAGNESIUM. Patient was hospitalized and became disabled. Patient recovered.

Tacrolimus Side Effects Report #4620463-6
Tacrolimus side effect was reported by a Consumer or non-health professional from on Mar 21, 2005. Male patient, 69 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood potassium increased, bone disorder, cerebrovascular accident, condition aggravated, dysphagia, emphysema, hilar lymphadenopathy, oesophageal squamous cell carcinoma. Tacrolimus dosage: 2MG AM, 1.5MG PM ORAL. During the same period patient was treated with BICARBONATE IN PLASTIC CONTAINER, AMLODIPINE, RANTIDINE, CALCIUM, CLOPIDOGREL BISULPHATE, FOLIC ACID, ALFACALCIDOL, COMBIVENT. Patient was hospitalized. Patient died.

Tacrolimus Side Effects Report #4682526-9
Tacrolimus side effect was reported by a Consumer or non-health professional from on May 27, 2005. Female patient, 59 years of age, weighting 135.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood pressure decreased, cardiomegaly, condition aggravated, deep vein thrombosis , haemodialysis, haemodynamic instability, haemoglobin decreased, infection . Tacrolimus dosage: 4 MG 2X PER 1 DAY; NASOGASTRIC. During the same period patient was treated with CORTICOSTEROIDS, MYCOPHENOLATE MOFETIL, METRONIDAZOLE, BACTRIM, MEROPENEM. Patient was hospitalized. Patient died on 05/05/2005.

Tacrolimus Side Effects Report #5158669-2
Tacrolimus side effect was reported by a Consumer or non-health professional from FRANCE on Nov 08, 2006. Male patient, 47 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: agitation, brain oedema, chromatopsia, condition aggravated, haemolytic uraemic syndrome, heart rate decreased, hyperreflexia, hypertension, meningorrhagia. Tacrolimus dosage: 4 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with CELLCEPT, PREDNISONE, OMEPRAZOLE, PROPRANOLOL, EUCALCIC, PRAVASTATIN, ASPEGIC, ZELTREX. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5066413-2
Tacrolimus side effect was reported by a Consumer or non-health professional from UNITED STATES on July 14, 2006. Female patient, 35 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: abdominal pain , chest pain , computerised tomogram abdomen abnormal, condition aggravated, hypertension, nausea , oesophagitis, tachycardia. Tacrolimus dosage: 2 MG 2X PER 1 DAY, ORAL; SEE IMAGE. During the same period patient was treated with CELLCEPT, PREDNISONE, ZENAPAX, CLONIDINE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5246390-1
Tacrolimus side effect was reported by a Physician from FRANCE on Feb 14, 2007. Male patient, weighting 176.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, hepatitis acute, liver transplant rejection. Tacrolimus dosage: 2 MG/FREQUENCY NOT PROVIDED. During the same period patient was treated with DIAMOX, BICARBONATE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5448282-1
Tacrolimus side effect was reported by a Physician from FRANCE on Sept 06, 2007. Male patient, weighting 176.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, hepatitis acute, liver transplant rejection. Tacrolimus dosage: 2 MG/FREQUENCY NOT PROVIDED. During the same period patient was treated with DIAMOX, BICARBONATE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4978840-X
Tacrolimus side effect was reported by a Physician from FRANCE on Apr 04, 2006. Female patient, 51 years of age, was diagnosed with pancreas islet cell transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, neurotoxicity, retinopathy, visual acuity reduced, visual disturbance. Tacrolimus dosage: 1 MG, BID, ORAL. During the same period patient was treated with RAPAMUNE, ZENAPAX. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4572959-3
Tacrolimus side effect was reported by a Physician from on Jan 25, 2005. Female patient, 83 years of age, weighting 86.86 lb, was diagnosed with myasthenia gravis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, cholinergic syndrome, condition aggravated, electrocardiogram st-t change, electrocardiogram t wave inversion, myasthenia gravis crisis. Tacrolimus dosage: 3.00 MG, ORAL; 3.00 MG, ORAL; 1.50 MG, ORAL; 1.20 MG, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, MESTINON, WARFARIN, PARAMIDIN, DIART, HERBESSOR R. Patient recovered.


Tacrolimus Side Effects Report #5986703-6
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 27, 2008. Female patient, 81 years of age, weighting 99.21 lb, was diagnosed with myasthenia gravis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, hyperglycaemia, interstitial lung disease, lymphocyte count decreased, post procedural complication, pulmonary embolism , restlessness, thymectomy. Tacrolimus dosage: 3 MG, /D, ORAL. During the same period patient was treated with PREDNISOLONE, MYTELASE, GASTER D ORODISPERSIBLE CRLET. Patient died on 11/13/2004.

Tacrolimus Side Effects Report #4627652-5
Tacrolimus side effect was reported by a Physician from on Mar 22, 2005. Female patient, 51 years of age, weighting 165.3 lb, was diagnosed with myasthenia gravis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diplopia, headache , white blood cell count increased. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, PREDNISOLONE. Patient recovered.

Tacrolimus Side Effects Report #5492827-2
Tacrolimus side effect was reported by a Physician from JAPAN on Oct 04, 2007. Male patient, 50 years of age, weighting 153.9 lb, was diagnosed with myasthenia gravis, gastritis, hypertension and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: colitis ulcerative, condition aggravated, diabetes mellitus, erysipelas, feeling hot, glycosylated haemoglobin increased, infection , melaena, swelling. Tacrolimus dosage: 3 MG, ORAL; 2 MG, ORAL. During the same period patient was treated with FAMOTIDINE, LOSARTAN POTASSIUM, PREDNISOLONE, SULFASALAZINE, MESALAMINE, CEFOPERAZONE, SOLUTIONS PARENTERAL NUTRITION. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5704630-6
Tacrolimus side effect was reported by a Physician from JAPAN on Mar 27, 2008. Female patient, 43 years of age, was diagnosed with myasthenia gravis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: body temperature decreased, bone marrow disorder, cheilitis, condition aggravated, enterocolitis, glossitis, hepatic function abnormal, herpes simplex , hyperglycaemia. Tacrolimus dosage: unknown. During the same period patient was treated with ATARAX, IMURAN. Patient recovered.

Tacrolimus Side Effects Report #5729773-2
Tacrolimus side effect was reported by a Physician from JAPAN on Apr 25, 2008. Female patient, 55 years of age, weighting 109.8 lb, was diagnosed with lupus nephritis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, lung infection, nephritis interstitial, pleural effusion. Tacrolimus dosage: 1 MG, ORAL 2 MG, ORAL 3 MG, ORAL 4 MG, ORAL. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, LIPITOR, LANSOPRAZOLE, BAYASPIRIN PER ORAL NOS, ALFAROL. Patient was hospitalized and became disabled. Patient recovered.

Tacrolimus Side Effects Report #5771681-5
Tacrolimus side effect was reported by a Physician from JAPAN on June 02, 2008. Female patient, 46 years of age, weighting 92.11 lb, was diagnosed with lupus nephritis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, enterocolitis, intestinal ischaemia, large intestinal ulcer, systemic lupus erythematosus. Tacrolimus dosage: 2 MG, /D, ORAL; 3 MG, /D, ORAL. During the same period patient was treated with METHYLPREDNISOLONE, GASTER D ORODISPERSIBLE CRLET, BACTAR, PURSENNID. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5989894-6
Tacrolimus side effect was reported by a Physician from JAPAN on Nov 28, 2008. Female patient, 35 years of age, weighting 132.3 lb, was diagnosed with lupus nephritis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: abortion missed, blood pressure increased, condition aggravated, glucose urine present, lupus nephritis, platelet count decreased. Tacrolimus dosage: 2 MG, /D, ORAL, 3MG, /D, ORAL. During the same period patient was treated with PREDNISOLONE, LOSARTAN POTASSIUM. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4570310-6
Tacrolimus side effect was reported by a Pharmacist from on Jan 27, 2005. Male patient, 20 years of age, weighting 108.2 lb, was diagnosed with lung transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, lung transplant rejection, renal impairment, thrombocytopenia. Tacrolimus dosage: 3MG TWO TIMES/DAY ORAL. During the same period patient was treated with PHYTONADIONE, FAMOTIDINE, DILTIAZEM, GANCICLOVIR, DOCUSATE, SULFAMETHOXAZOLE, CLONIDINE, FERROUS SULPHATE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5325849-2
Tacrolimus side effect was reported by a Health Professional from BELGIUM on Apr 26, 2007. Female patient, 49 years of age, was diagnosed with liver transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, congenital cystic kidney disease, dialysis , renal impairment. Tacrolimus dosage: 2 MG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, DACLIZUMAB, METHYLPREDNISOLONE, AMPICILLIN, CEFOTAXIME, TOBRAMYCIN. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5671572-4
Tacrolimus side effect was reported by a Consumer or non-health professional from JAPAN on Feb 26, 2008. Female patient, 69 years of age, weighting 116.8 lb, was diagnosed with interstitial lung disease and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, pneumonia cytomegaloviral. Tacrolimus dosage: 2 MG, BID, ORAL. During the same period patient was treated with PREDONONINE, ULCERLMIN, NEORAL, SOL MEDROL, SOL MEDROL. Patient died on 02/25/2008.


Tacrolimus Side Effects Report #5521548-2
Tacrolimus side effect was reported by a Health Professional from JAPAN on Nov 05, 2007. Female patient, 41 years of age, weighting 125.7 lb, was diagnosed with interstitial lung disease and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, interstitial lung disease, respiratory failure. Tacrolimus dosage: 2 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, STOGAR, FOSAMAC. Patient recovered.

Tacrolimus Side Effects Report #4961761-6
Tacrolimus side effect was reported by a Health Professional from GERMANY on Mar 16, 2006. Male patient, 61 years of age, weighting 174.2 lb, was diagnosed with fungal infection  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, condition aggravated, convulsion, creatinine renal clearance decreased, cystitis, cytomegalovirus infection , disease recurrence, dry skin, epstein-barr virus infection. Tacrolimus dosage: unknown. During the same period patient was treated with POSACONAZOLE, ACYCLOVIR, SANDIMMUNE, DECORTIN, CELLCEPT, GANCICLOVIR. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #6122312-6
Tacrolimus side effect was reported by a Health Professional from UNITED KINGDOM on Mar 03, 2009. Female patient, 26 years of age, was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, red blood cell abnormality, thrombocytopenia, thrombotic microangiopathy. Tacrolimus dosage: 0.1 MG/KG, /D. During the same period patient was treated with SIROLIMUS, CYCLOSPORINE, ANTITHYMOCITE IMMUNOGLOBULIN. Patient recovered.

Tacrolimus Side Effects Report #5656223-7
Tacrolimus side effect was reported by a Physician from JAPAN on Feb 18, 2008. Female patient, 18 years of age, weighting 110.2 lb, was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: back pain , condition aggravated, lupus nephritis, varicella. Tacrolimus dosage: 2 MG, UID/QD, ORAL; 1 MG, ORAL; 2 MG, ORAL. During the same period patient was treated with PREDNISOLONE. Patient recovered.