Sprycel and confusional state Patient Reports February 11, 2012

Sprycel Side Effects Report #5372381-6
Sprycel side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 13, 2007. Male patient, 54 years of age, weighting 180.8 lb, was diagnosed with leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: abnormal dreams, confusional state, hallucination, increased appetite, somnolence. Sprycel dosage: unknown. During the same period patient was treated with SINGULAIR, GLIPIZIDE, METFORMIN, UROXATRAL, GABAPENTIN, ALLOPURINOL, ENALAPRIL. Patient recovered.

Sprycel Side Effects Report #5422082-0
Sprycel side effect was reported by a Physician from UNITED STATES on Aug 16, 2007. Male patient, 74 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: confusional state, coordination abnormal, dysarthria, pancytopenia, pleural effusion, rash . Sprycel dosage: 3 SEPARATE CHALLENGES 70MG,50MG+35MGBID.DATES INTERMITANT JUL06- PRESENT.DOSE REDUCED TO 20 MGBID. During the same period patient was treated with PROPRANOLOL, HYDRALAZINE, POTASSIUM CHLORIDE, VIAGRA, VITAMIN E, FOLIC ACID, BETACAROTENE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Sprycel Side Effects Report #6071688-7
Sprycel side effect was reported by a Physician from SPAIN on Feb 05, 2009. Male patient, 74 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: confusional state, thrombocytopenia, urinary retention, weight decreased. Sprycel dosage: INITIATED AT A DOSE OF 100 MG/DAY.. Patient recovered.

Sprycel Side Effects Report #5797699-4
Sprycel side effect was reported by a Health Professional from FRANCE on June 27, 2008. Female patient, 76 years of age, was diagnosed with acute lymphocytic leukaemia, hypertension and was treated with Sprycel. After drug was administered, patient experienced the following side effects: cachexia, cerebellar syndrome, confusional state, renal failure. Sprycel dosage: RESTARTED ON 16APR08 TO 29APR08, 100 MG, ORAL.. During the same period patient was treated with DEXAMETHASONE, VINCRISTINE, HYTACAND, CELECTOL. Patient died on 05/27/2008.


Sprycel Side Effects Report #5804799-9
Sprycel side effect was reported by a Consumer or non-health professional from FRANCE on July 02, 2008. Female patient, 76 years of age, was diagnosed with acute lymphocytic leukaemia, hypertension and was treated with Sprycel. After drug was administered, patient experienced the following side effects: cachexia, cerebellar syndrome, cognitive disorder, confusional state, renal failure. Sprycel dosage: INTERRUPTED ON 08APR08,RESTARTED ON 16APR08 TO 29APR08, 100 MG, ORAL.. During the same period patient was treated with VINCRISTINE SULPHATE, DEXAMETHASONE, HYTACAND, CELECTOL. Patient died on 05/27/2008.

Sprycel Side Effects Report #5813573-9
Sprycel side effect was reported by a Consumer or non-health professional from FRANCE on July 10, 2008. Female patient, 76 years of age, was diagnosed with acute lymphocytic leukaemia, hypertension and was treated with Sprycel. After drug was administered, patient experienced the following side effects: cachexia, cerebellar syndrome, cognitive disorder, confusional state, renal failure. Sprycel dosage: INTERRUPTED ON 08APR08,RESTARTED ON 16APR08 TO 29APR08, 100 MG, ORAL.. During the same period patient was treated with VINCRISTINE SULPHATE, DEXAMETHASONE, HYTACAND, CELECTOL. Patient died on 05/27/2008.

Sprycel Side Effects Report #5874051-4
Sprycel side effect was reported by a Consumer or non-health professional from FRANCE on Sept 04, 2008. Female patient, 76 years of age, was diagnosed with acute lymphocytic leukaemia, hypertension and was treated with Sprycel. After drug was administered, patient experienced the following side effects: cachexia, cerebellar syndrome, cognitive disorder, confusional state, renal failure. Sprycel dosage: INTERRUPTED ON 08APR08,RESTARTED ON 16APR08 TO 29APR08, 100 MG, ORAL.. During the same period patient was treated with VINCRISTINE SULPHATE, DEXAMETHASONE, HYTACAND, CELECTOL. Patient died on 05/27/2008.

Sprycel Side Effects Report #5618778-8
Sprycel side effect was reported by a Consumer or non-health professional from FRANCE on Feb 01, 2008. Male patient, 73 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: confusional state, thrombotic microangiopathy. Sprycel dosage: 03JAN08-10JAN08 140MG,11JAN08-16JAN08 280MG. During the same period patient was treated with VINCRISTINE, METHOTREXATE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Sprycel Side Effects Report #5631750-7
Sprycel side effect was reported by a Consumer or non-health professional from FRANCE on Feb 14, 2008. Male patient, 73 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: accidental overdose, confusional state, diarrhoea, escherichia urinary tract infection, respiratory disorder, thrombotic microangiopathy. Sprycel dosage: 03JAN08-10JAN08 140MG,11JAN08-16JAN08 280MG;18JAN-27JAN08,140MG.INTERRUPTED ON 27JAN08.. During the same period patient was treated with VINCRISTINE, METHOTREXATE, DEXAMETHASONE, CYTARABINE, METHYLPREDNISOLONE, NEUPOGEN. Patient was hospitalized. Patient recovered.


Sprycel Side Effects Report #5719652-9
Sprycel side effect was reported by a Consumer or non-health professional from FRANCE on Apr 23, 2008. Male patient, 73 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: accidental overdose, confusional state, diarrhoea, escherichia urinary tract infection, respiratory disorder, thrombotic microangiopathy. Sprycel dosage: 03JAN08-10JAN08 140MG,11JAN08-16JAN08 280MG;18JAN-27JAN08,140MG.. During the same period patient was treated with VINCRISTINE, METHOTREXATE, DEXAMETHASONE, CYTARABINE, METHYLPREDNISOLONE, NEUPOGEN. Patient was hospitalized. Patient recovered.

Sprycel Side Effects Report #5564875-5
Sprycel side effect was reported by a Health Professional from FRANCE on Dec 14, 2007. Female patient, 72 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Sprycel. After drug was administered, patient experienced the following side effects: anaemia, cardio-respiratory arrest, confusional state, haematoma, phlebitis, pulmonary embolism , renal failure, tumour lysis syndrome. Sprycel dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, METHOTREXATE, DEXAMETHASONE, CYTARABINE, METHYLPREDNISOLONE, NEUPOGEN, RASBURICASE, HEPARIN. Patient was hospitalized. Patient died on 10/29/2007.