Sorafenib and gastrointestinal haemorrhage Patient Reports February 10, 2012

Sorafenib Side Effects Report #5616490-2
Sorafenib side effect was reported by a Physician from THAILAND on Oct 15, 2007. Male patient, 80 years of age, weighting 156.5 lb, was diagnosed with renal cell carcinoma, prophylaxis against gastrointestinal ulcer, vitamin supplementation, cardiac disorder and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, oedema, oedema peripheral. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with NEXIUM, FOLIC ACID, CONCOR, TANAKAN, ISOTRATE, VITAMIN B1. Patient was hospitalized. Patient died on 10/02/2007.

Sorafenib Side Effects Report #5616682-2
Sorafenib side effect was reported by a Physician from THAILAND on Oct 15, 2007. Male patient, 80 years of age, weighting 156.5 lb, was diagnosed with renal cell carcinoma, prophylaxis against gastrointestinal ulcer, vitamin supplementation, cardiac disorder and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, oedema, oedema peripheral. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with NEXIUM, FOLIC ACID, CONCOR, TANAKAN, ISOTRATE, VITAMIN B1. Patient was hospitalized. Patient died on 10/02/2007.

Sorafenib Side Effects Report #6107881-4
Sorafenib side effect was reported by a Physician from UNITED STATES on Mar 05, 2009. Female patient, 59 years of age, weighting 133.0 lb, was diagnosed with pulmonary arterial hypertension and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, catheter related infection, fall , gastrointestinal haemorrhage, hypotension, renal failure acute. Sorafenib dosage: 200 MG TID PO. Patient died on 02/27/2009.

Sorafenib Side Effects Report #5451157-5
Sorafenib side effect was reported by a Physician from NETHERLANDS on Sept 04, 2007. Male patient, 65 years of age, was diagnosed with non-small cell lung cancer, intercostal neuralgia, prophylaxis, dyspnoea and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, leukopenia, thrombocytopenia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with CISPLATIN, GEMCITABINE, AMITRIPTYLINE, LYRICA, OMEPRAZOLE, ATROVENT. Patient was hospitalized. Patient died on 08/26/2007.


Sorafenib Side Effects Report #5147837-1
Sorafenib side effect was reported by a Physician from UNITED STATES on Oct 31, 2006. Female patient, 63 years of age, was diagnosed with non-small cell lung cancer, hypothyroidism, blood cholesterol increased, hypertension and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal disorder, gastrointestinal haemorrhage, occult blood positive, pancytopenia, petechiae. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with CARBOPLATIN, PACLITAXEL, SYNTHROID, ZOCOR, VASOTEC. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5187705-2
Sorafenib side effect was reported by a Physician from UNITED STATES on Oct 31, 2006. Female patient, 63 years of age, weighting 125.7 lb, was diagnosed with non-small cell lung cancer and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: bone marrow failure, diarrhoea, dyspnoea, epistaxis, gastroduodenitis haemorrhagic, gastrointestinal haemorrhage, gingival bleeding, occult blood positive, pancytopenia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with CARBOPLATIN, PACLITAXEL. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5649432-4
Sorafenib side effect was reported by a Physician from GERMANY on Feb 20, 2008. Female patient, 57 years of age, weighting 99.21 lb, was diagnosed with non-small cell lung cancer and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with PACLITAXEL, CARBOPLATIN, ZOMETA, NOVALGIN, DURAGESIC, VOLTAREN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #4978579-0
Sorafenib side effect was reported by a Consumer or non-health professional from ISRAEL on Apr 06, 2006. Male patient, 71 years of age, weighting 160.9 lb, was diagnosed with neoplasm and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: acute myocardial infarction, duodenal ulcer, gastric ulcer, gastrointestinal haemorrhage, malignant neoplasm progression. Sorafenib dosage: 400 MG, BID, ORAL. During the same period patient was treated with LCV, BAY, ATENOLOL, MEGACE, BONDORMIN, XANAGIS. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #4983100-7
Sorafenib side effect was reported by a Consumer or non-health professional from ISRAEL on Apr 06, 2006. Male patient, 71 years of age, weighting 160.9 lb, was diagnosed with neoplasm and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: acute myocardial infarction, disease progression, duodenal ulcer, gastric ulcer, gastrointestinal haemorrhage. Sorafenib dosage: 400 MG, BID, ORAL. During the same period patient was treated with LCV, ATENOLOL, MEGACE, BONDORMIN, XANAGIS. Patient was hospitalized. Patient recovered.


Sorafenib Side Effects Report #5003172-3
Sorafenib side effect was reported by a Health Professional from ISRAEL on May 04, 2006. Male patient, 71 years of age, weighting 160.9 lb, was diagnosed with neoplasm and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: acute myocardial infarction, duodenal ulcer, gastric ulcer, gastrointestinal haemorrhage, malignant neoplasm progression, pancreatic carcinoma metastatic. Sorafenib dosage: 400 MG, BID, ORAL. During the same period patient was treated with LCV, BAY, ATENOLOL, MEGACE, BONDORMIN, XANAGIS, PANCREOFLAT. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5216975-7
Sorafenib side effect was reported by a Physician from UNITED STATES on Aug 19, 2006. Female patient, 78 years of age, weighting 121.3 lb, was diagnosed with metastatic renal cell carcinoma, pulmonary embolism , gastrooesophageal reflux disease, hypertension, hypothyroidism, nausea , pain  and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: coagulopathy, fall , gastrointestinal haemorrhage, haemorrhoids, hip fracture, hypotension, pulmonary embolism , supraventricular tachycardia, syncope. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with COUMADIN, PROTONIX, DIOVAN, LEVOTHYROXINE, COMPAZINE, VICODIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5223821-4
Sorafenib side effect was reported by a Physician from UNITED STATES on Aug 14, 2006. Female patient, 78 years of age, weighting 121.3 lb, was diagnosed with metastatic renal cell carcinoma, pulmonary embolism , gastrooesophageal reflux disease, hypertension, hypothyroidism, nausea , pain  and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: coagulopathy, fall , gastrointestinal haemorrhage, hip fracture, pulmonary embolism , supraventricular tachycardia, syncope. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with COUMADIN, PROTONIX, DIOVAN, LEVOTHYROXINE, COMPAZINE, VICODIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5263565-6
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 09, 2007. Male patient, 78 years of age, weighting 202.8 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anorexia, dizziness , gastrointestinal haemorrhage, loss of consciousness, pain , pain in extremity, urinary retention. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with NITROGLYCERIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5324959-3
Sorafenib side effect was reported by a Physician from UNITED STATES on Feb 07, 2007. Female patient, 78 years of age, weighting 121.3 lb, was diagnosed with metastatic renal cell carcinoma, pulmonary embolism , gastrooesophageal reflux disease, hypertension, hypothyroidism, nausea , pain  and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: blood chloride decreased, coagulopathy, fall , gastrointestinal haemorrhage, haematocrit decreased, haemoglobin decreased, haemorrhoids, hip fracture, hypotension. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with COUMADIN, PROTONIX, DIOVAN, LEVOTHYROXINE, COMPAZINE, VICODIN. Patient was hospitalized. Patient recovered.


Sorafenib Side Effects Report #5207013-0
Sorafenib side effect was reported by a Physician from UNITED STATES on Jan 03, 2007. Male patient, 69 years of age, weighting 176.4 lb, was diagnosed with metastatic renal cell carcinoma, oedema, gastrooesophageal reflux disease, hypothyroidism, fatigue, pain  and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: fatigue, gastrointestinal haemorrhage, haemoglobin decreased, hypocalcaemia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with LASIX, OMEPRAZOLE, SYNTHROID, TESTOSTERONE, ROXANOL, MS CONTIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5122663-8
Sorafenib side effect was reported by a Physician from UNITED STATES on Nov 17, 2005. Male patient, 69 years of age, weighting 176.4 lb, was diagnosed with metastatic renal cell carcinoma, oedema, gastrooesophageal reflux disease, hypothyroidism, fatigue, pain  and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: abasia, depression , dizziness , fatigue, gastrointestinal haemorrhage, haemoglobin decreased, hypocalcaemia, hypotension, hypovolaemia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with LASIX, OMEPRAZOLE, SYNTHROID, TESTOSTERONE, ROXANOL, MS CONTIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5074827-X
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED STATES on July 26, 2006. Male patient, 68 years of age, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: alopecia, dehydration, diverticulitis, dysphagia, gastrointestinal haemorrhage, intestinal perforation, malnutrition, nausea . Sorafenib dosage: unknown. During the same period patient was treated with SYNTHROID, ZYRTEC, ZOLOFT, PRILOSEC, BENADRYL. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5141124-3
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 31, 2006. Male patient, 68 years of age, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: alopecia, asthenia, dehydration, disease progression, diverticulum, dysphagia, gastric haemorrhage, gastrointestinal haemorrhage, haematochezia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with SYNTHROID, ZYRTEC, ZOLOFT, PRILOSEC, BENADRYL. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5280095-6
Sorafenib side effect was reported by a Physician from UNITED STATES on Dec 06, 2006. Male patient, 67 years of age, weighting 238.1 lb, was diagnosed with metastatic renal cell carcinoma, nausea , hypertension, pain , pulmonary embolism  and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anaemia, duodenal ulcer, dyspnoea, gastritis, gastrointestinal haemorrhage, gastrooesophageal reflux disease, hiatus hernia, hypotension, international normalised ratio increased. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with ZOFRAN, TOPROL, NORVASC, OXYCONTIN, COUMADIN. Patient was hospitalized. Patient died on 12/13/2005.


Sorafenib Side Effects Report #5102614-2
Sorafenib side effect was reported by a Physician from UNITED STATES on Dec 28, 2005. Male patient, 63 years of age, weighting 158.7 lb, was diagnosed with metastatic renal cell carcinoma, hypertension, diabetes mellitus and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: aortic valve sclerosis, atrioventricular block, bradycardia, bundle branch block right, duodenal ulcer, gastrointestinal haemorrhage, ileus, myocardial infarction, post procedural complication. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with ATENOLOL, INSULIN REGULAR HUMULIN, LANTUS. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #4937741-3
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 28, 2006. Male patient, 63 years of age, weighting 158.7 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: abdominal discomfort, aortic valve disease, atrioventricular block, bundle branch block right, duodenal ulcer, electrocardiogram qrs complex prolonged, gastrointestinal haemorrhage, haematocrit decreased, ileus. Sorafenib dosage: 400 MG ONCE ORAL; 400 MG BID ORAL. During the same period patient was treated with ATENOLOL, HUMULIN R, LANTUS, OXYCONTIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5107889-1
Sorafenib side effect was reported by a Physician from UNITED STATES on Nov 10, 2005. Female patient, 62 years of age, weighting 92.59 lb, was diagnosed with metastatic renal cell carcinoma, analgesic effect, antiemetic supportive care, vomiting, hypertension, oedema and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: cardiac failure congestive, gastrointestinal haemorrhage, hyponatraemia, respiratory failure. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with HYDROCODONE, ATIVAN, COMPAZINE, METOPROLOL, LASIX. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5076491-2
Sorafenib side effect was reported by a Physician from FRANCE on Mar 28, 2006. Male patient, 59 years of age, weighting 156.5 lb, was diagnosed with metastatic renal cell carcinoma, hypertension and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anaemia, arteriosclerosis coronary artery, carotid artery stenosis, gastrointestinal haemorrhage, hypertension, myocardial infarction, myocardial ischaemia, oesophagitis, phlebitis. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with MONOTILDIEM, LASILIX, APROVEL. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5030792-2
Sorafenib side effect was reported by a Consumer or non-health professional from FRANCE on June 05, 2006. Male patient, 59 years of age, weighting 155.6 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anaemia, aplasia pure red cell, arteriosclerosis coronary artery, blood pressure increased, coronary artery stenosis, duodenitis, gastrointestinal haemorrhage, hypertension, infusion site phlebitis. Sorafenib dosage: unknown. During the same period patient was treated with LASILIX, APROVEL. Patient was hospitalized. Patient recovered.


Sorafenib Side Effects Report #5034414-6
Sorafenib side effect was reported by a Physician from FRANCE on June 05, 2006. Male patient, 59 years of age, weighting 155.6 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anaemia, arteriosclerosis coronary artery, blood pressure increased, coronary artery stenosis, gastrointestinal haemorrhage, myocardial infarction, myocardial ischaemia, oesophagitis, phlebitis. Sorafenib dosage: unknown. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5042614-4
Sorafenib side effect was reported by a Consumer or non-health professional from FRANCE on June 05, 2006. Male patient, 59 years of age, weighting 155.6 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anaemia, arteriosclerosis coronary artery, blood pressure increased, duodenitis, gastrointestinal haemorrhage, myocardial infarction, oesophagitis, phlebitis. Sorafenib dosage: unknown. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5161001-1
Sorafenib side effect was reported by a Physician from POLAND on Oct 12, 2006. Female patient, 57 years of age, weighting 114.6 lb, was diagnosed with metastatic renal cell carcinoma, haemoglobin decreased, urinary tract infection , blood calcium decreased and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: cardiovascular insufficiency, gastrointestinal haemorrhage, haemoglobin decreased, mechanical ileus, shock. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with INTERFERON, WHOLE BLOOD, WHOLE BLOOD, CIPROFLOXACIN, BLOOD SERUM, CALCIUM. Patient was hospitalized. Patient died on 10/06/2006.

Sorafenib Side Effects Report #5192672-1
Sorafenib side effect was reported by a Physician from POLAND on Oct 12, 2006. Female patient, 57 years of age, weighting 114.6 lb, was diagnosed with metastatic renal cell carcinoma, haemoglobin decreased, urinary tract infection , blood calcium decreased and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: cardiovascular insufficiency, gastrointestinal haemorrhage, haemoglobin decreased, mechanical ileus. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with INTERFERON, WHOLE BLOOD, WHOLE BLOOD, CIPROFLOXACIN, BLOOD SERUM, CALCIUM. Patient was hospitalized. Patient died on 10/06/2006.

Sorafenib Side Effects Report #5119310-8
Sorafenib side effect was reported by a Physician from UNITED STATES on May 10, 2006. Male patient, 54 years of age, weighting 143.3 lb, was diagnosed with metastatic renal cell carcinoma, hypertension, pain , metastases to bone, peptic ulcer , back pain , anaemia and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: duodenal ulcer, gastrointestinal haemorrhage. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with LISINOPRIL, NORVASC, HYDROCHLOROTHIAZIDE, OXYCODONE, ZOMETA, NEXIUM, BACLOFEN, FERROUS GLUCONATE. Patient was hospitalized. Patient recovered.


Sorafenib Side Effects Report #5122841-8
Sorafenib side effect was reported by a Physician from UNITED STATES on May 10, 2006. Male patient, 54 years of age, weighting 143.3 lb, was diagnosed with metastatic renal cell carcinoma, hypertension, pain , metastases to bone, peptic ulcer , back pain , anaemia and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: bone lesion, dizziness , duodenal ulcer, gastrointestinal haemorrhage, haemoglobin decreased. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with LISINOPRIL, NORVASC, HYDROCHLOROTHIAZIDE, OXYCODONE, ZOMETA, NEXIUM, BACLOFEN, FERROUS GLUCONATE. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5019442-9
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED STATES on May 22, 2006. Male patient, 54 years of age, weighting 143.0 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: abdominal pain upper, dizziness , duodenal ulcer, faeces discoloured, gastrointestinal haemorrhage, haematemesis, nausea . Sorafenib dosage: 400 MG, BID, ORAL. During the same period patient was treated with LISINOPRIL, NORVASC, HYDROCHLOROTHIAZIDE, OXYCODONE, ZOMETA, NEXIUM, BACLOFEN, FERROUS GLUCONATE. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #4953122-0
Sorafenib side effect was reported by a Physician from UNITED STATES on Mar 13, 2006. Female patient, weighting 173.3 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: abdominal pain , anaemia, disease progression, duodenal neoplasm, fall , fatigue, gastrointestinal haemorrhage, haemoglobin decreased. Sorafenib dosage: 400 MG, BID, ORAL. During the same period patient was treated with OXYCONTIN, OXYCODONE, TEMAZEPAM, AMLODIPINE, KLONOPIN, DIOVAN, ATARAX, NPH INSULIN. Patient died on 11/22/2005.

Sorafenib Side Effects Report #4955031-X
Sorafenib side effect was reported by a Physician from UNITED STATES on Mar 13, 2006. Female patient, weighting 173.3 lb, was diagnosed with metastatic renal cell carcinoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: abdominal pain , anaemia, duodenal neoplasm, fall , gastrointestinal haemorrhage, malignant neoplasm progression, metastatic renal cell carcinoma. Sorafenib dosage: 400 MG, BID, ORAL. During the same period patient was treated with OXYCONTIN, OXYCODONE, TEMAZEPAM, AMLODIPINE, KLONOPIN, DIOVAN, ATARAX, NPH INSULIN. Patient died on 11/22/2005.

Sorafenib Side Effects Report #4974011-1
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 04, 2006. Male patient, 26 years of age, weighting 164.9 lb, was diagnosed with metastatic malignant melanoma and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: anaemia, gastrointestinal haemorrhage. Sorafenib dosage: unknown. During the same period patient was treated with DACARBAZINE, FERROUS SULPHATE, OMEPRAZOLE, TRANEXAMIC ACID, CEPHALEXIN, MILPAR. Patient was hospitalized. Patient recovered.


Sorafenib Side Effects Report #6088352-0
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 16, 2009. Male patient, 76 years of age, weighting 158.7 lb, was diagnosed with lung neoplasm malignant and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: arterial thrombosis, blood creatinine increased, dehydration, dysphagia, gastrointestinal haemorrhage, neutropenia, peripheral ischaemia, platelet count decreased. Sorafenib dosage: TOTAL DAILY DOSE: 400 MG UNIT DOSE: 200 MG. During the same period patient was treated with CISPLATIN, ETOPOSIDE, LISINOPRIL, HYTRIN. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5136997-4
Sorafenib side effect was reported by a Physician from CANADA on May 02, 2006. Male patient, 70 years of age, weighting 224.9 lb, was diagnosed with hepatic neoplasm malignant, gastrooesophageal reflux disease, pain , hypercholesterolaemia, diabetes mellitus, atrial fibrillation , hypertension and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: aortic valve stenosis, arteriovenous malformation , atrial fibrillation , dehydration, dilatation atrial, disease progression, gastrointestinal haemorrhage, hypercalcaemia, mitral valve stenosis. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with DOXORUBICIN, PROTONIX, OXYCONTIN, LIPITOR, ACTOS, TOPROL, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5400150-7
Sorafenib side effect was reported by a Physician from UNITED STATES on July 27, 2007. Male patient, 70 years of age, weighting 224.9 lb, was diagnosed with hepatic neoplasm malignant, gastrooesophageal reflux disease, pain , hypercholesterolaemia, diabetes mellitus, hypertension, seasonal allergy and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: atrial fibrillation , gastrointestinal arteriovenous malformation, gastrointestinal haemorrhage, hypercalcaemia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with DOXORUBICIN, PROTONIX, OXYCONTIN, LIPITOR, ACTOS, HYDROCHLOROTHIAZIDE, LORATADINE. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5610984-1
Sorafenib side effect was reported by a Physician from UNITED STATES on Jan 23, 2008. Male patient, 70 years of age, weighting 224.9 lb, was diagnosed with hepatic neoplasm malignant, gastrooesophageal reflux disease, pain , hypercholesterolaemia, diabetes mellitus, hypertension, seasonal allergy and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: arteriovenous malformation , atrial fibrillation , gastrointestinal haemorrhage, hypercalcaemia. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with DOXORUBICIN, PROTONIX, OXYCONTIN, LIPITOR, ACTOS, HYDROCHLOROTHIAZIDE, LORATADINE. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5115664-7
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 11, 2006. Male patient, 63 years of age, weighting 158.7 lb, was diagnosed with hepatic neoplasm malignant and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: alcoholic liver disease, gastrointestinal haemorrhage. Sorafenib dosage: unknown. During the same period patient was treated with DOXORUBICIN, VITAMIN K, FUROSEMIDE, SALINE, PANTOPRAZOLE, TERLIPRESSIN. Patient was hospitalized. Patient died on 09/19/2006.


Sorafenib Side Effects Report #5120314-X
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 11, 2006. Male patient, 63 years of age, weighting 158.7 lb, was diagnosed with hepatic neoplasm malignant and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: alcoholic liver disease, cellulitis , contusion, encephalopathy, gastrointestinal haemorrhage, hallucination, hypotension, renal impairment. Sorafenib dosage: unknown. During the same period patient was treated with DOXORUBICIN, VITAMIN K, FUROSEMIDE, SALINE, PANTOPRAZOLE, TERLIPRESSIN. Patient was hospitalized. Patient died on 09/19/2006.

Sorafenib Side Effects Report #5142134-2
Sorafenib side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 11, 2006. Male patient, 63 years of age, weighting 158.7 lb, was diagnosed with hepatic neoplasm malignant and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: cellulitis , contusion, encephalopathy, fall , fatigue, gait disturbance, gastrointestinal haemorrhage, hallucination. Sorafenib dosage: unknown. During the same period patient was treated with DOXORUBICIN, VITAMIN K, FUROSEMIDE, SALINE, PANTOPRAZOLE, TERLIPRESSIN. Patient was hospitalized. Patient died on 09/19/2006.

Sorafenib Side Effects Report #5291903-7
Sorafenib side effect was reported by a Physician from ITALY on Apr 02, 2007. Male patient, 57 years of age, weighting 198.4 lb, was diagnosed with hepatic neoplasm malignant, insomnia, hypertension and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with LORAZEPAM, NEBIVOLOL. Patient died on 04/13/2006.

Sorafenib Side Effects Report #5447305-3
Sorafenib side effect was reported by a Physician from THAILAND on Aug 30, 2007. Male patient, 80 years of age, weighting 156.5 lb, was diagnosed with prophylaxis against gastrointestinal ulcer, vitamin supplementation, cardiac disorder and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, oedema peripheral. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with NEXIUM, FOLIC ACID, BISOPROLOL FUMARATE, TANAKAN, ISOTRATE, VITAMIN B1. Patient was hospitalized. Patient recovered.

Sorafenib Side Effects Report #5448672-7
Sorafenib side effect was reported by a Physician from THAILAND on Sept 06, 2007. Male patient, 80 years of age, weighting 156.5 lb, was diagnosed with prophylaxis against gastrointestinal ulcer, vitamin supplementation, cardiac disorder and was treated with Sorafenib. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, oedema peripheral. Sorafenib dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with NEXIUM, FOLIC ACID, BISOPROLOL FUMARATE, TANAKAN, ISOTRATE, VITAMIN B1. Patient was hospitalized. Patient recovered.