Sirolimus and disease recurrence Patient Reports February 11, 2012

Sirolimus Side Effects Report #4647249-0
Sirolimus side effect was reported by a Consumer or non-health professional from on Apr 15, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: disease recurrence, kidney transplant rejection. Sirolimus dosage: unknown. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5320327-9
Sirolimus side effect was reported by a Physician from BELGIUM on Apr 27, 2007. Male patient, 43 years of age, weighting 172.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: disease recurrence, focal glomerulosclerosis, transplant rejection. Sirolimus dosage: unknown. During the same period patient was treated with DACLIZUMAB, TACROLIMUS. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5331385-X
Sirolimus side effect was reported by a Physician from BELGIUM on May 18, 2007. Male patient, 43 years of age, weighting 172.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: disease recurrence, focal glomerulosclerosis, transplant rejection. Sirolimus dosage: unknown. During the same period patient was treated with DACLIZUMAB, TACROLIMUS. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5571593-6
Sirolimus side effect was reported by a Physician from BELGIUM on Dec 20, 2007. Male patient, 43 years of age, weighting 172.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: disease recurrence, focal segmental glomerulosclerosis. Sirolimus dosage: unknown. During the same period patient was treated with DACLIZUMAB, TACROLIMUS. Patient was hospitalized. Patient recovered.


Sirolimus Side Effects Report #5574571-6
Sirolimus side effect was reported by a Physician from BELGIUM on Dec 20, 2007. Male patient, 43 years of age, weighting 172.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: disease recurrence, focal segmental glomerulosclerosis. Sirolimus dosage: unknown. During the same period patient was treated with DACLIZUMAB, TACROLIMUS. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5029090-2
Sirolimus side effect was reported by a Health Professional from FRANCE on June 12, 2006. Female patient, 39 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: arteriovenous fistula thrombosis, body temperature increased, candida sepsis, cardiac valve vegetation, disease recurrence, endocarditis , mycotic aneurysm, renal aneurysm. Sirolimus dosage: 5 MG 1X PER 1 DAY ORAL; SEE IMAGE. During the same period patient was treated with CELLCEPT, SOLUPRED, AMLODIPINE BESYLATE, HUMALOG. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5053134-5
Sirolimus side effect was reported by a Health Professional from BELGIUM on July 03, 2006. Male patient was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: blood creatinine increased, disease recurrence, focal glomerulosclerosis, proteinuria. Sirolimus dosage: 15 + 4 + 5MG 1X PER 1 DAY ORAL - SEE IMAGE. During the same period patient was treated with TACROLIMUS, ZENAPAX, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5053954-7
Sirolimus side effect was reported by a Physician from BELGIUM on July 03, 2006. Male patient was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: disease recurrence, focal glomerulosclerosis. Sirolimus dosage: 15 MG 1X PER 1 DAY ORAL; SEE IMAGE. During the same period patient was treated with TACROLIMUS, ZENAPAX, CORTICOSTEROIDS. Patient was hospitalized. Patient died.

Sirolimus Side Effects Report #5033248-6
Sirolimus side effect was reported by a Consumer or non-health professional from BELGIUM on June 08, 2006. Male patient was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: blood creatinine increased, disease recurrence, focal glomerulosclerosis, proteinuria. Sirolimus dosage: 15 MG 1X PER 1 DAY ORAL; SEE IMAGE. During the same period patient was treated with TACROLIMUS, ZENAPAX, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.