Sirolimus and complications of transplanted kidney Patient Reports February 11, 2012

Sirolimus Side Effects Report #5096644-7
Sirolimus side effect was reported by a Consumer or non-health professional from ITALY on Aug 24, 2006. Female patient, 40 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood triglycerides increased, blood urea increased, complications of transplanted kidney, platelet count decreased. Sirolimus dosage: 4 MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5162137-1
Sirolimus side effect was reported by a Health Professional from FRANCE on Nov 09, 2006. Female patient, 40 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: anaemia, arteriovenous fistula, biopsy kidney abnormal, complications of transplanted kidney, condition aggravated, effusion, haemodialysis, haemorrhage. Sirolimus dosage: 15 MG DAILY FOR 2 DAYS AND THEN 8 MG DAILY ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5124717-9
Sirolimus side effect was reported by a Consumer or non-health professional from FRANCE on Sept 29, 2006. Female patient, 37 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, kidney transplant rejection. Sirolimus dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with CELLCEPT, ZENAPAX. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #4545291-1
Sirolimus side effect was reported by a Consumer or non-health professional from on Dec 28, 2004. Female patient, 37 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, kidney transplant rejection. Sirolimus dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with ZENEPAX. Patient was hospitalized. Patient recovered.


Sirolimus Side Effects Report #4547246-X
Sirolimus side effect was reported by a Health Professional from on Dec 30, 2004. Female patient, 37 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, glomerulonephritis membranous, kidney transplant rejection. Sirolimus dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with CELLCEPT, ZENAPAX. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #4787084-6
Sirolimus side effect was reported by a Consumer or non-health professional from FRANCE on Sept 27, 2005. Female patient, 37 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, glomerulonephritis membranous, kidney transplant rejection. Sirolimus dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT, ZENAPAX. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #4788785-6
Sirolimus side effect was reported by a Consumer or non-health professional from FRANCE on Sept 27, 2005. Female patient, 37 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, glomerulonephritis membranous, kidney transplant rejection. Sirolimus dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT, ZENEPAX. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5262617-4
Sirolimus side effect was reported by a Physician from UNITED STATES on Feb 28, 2007. Male patient was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, condition aggravated, hypertension. Sirolimus dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ZENAPAX. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5276097-6
Sirolimus side effect was reported by a Physician from UNITED STATES on Mar 20, 2007. Male patient was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney. Sirolimus dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ZENAPAX. Patient was hospitalized. Patient recovered.


Sirolimus Side Effects Report #5508705-6
Sirolimus side effect was reported by a Physician from CANADA on Nov 01, 2007. Male patient, weighting 183.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: clostridial infection, complications of transplanted kidney, deep vein thrombosis , intra-abdominal haematoma, myocardial infarction, pelvic haematoma, sepsis , thrombocytopenia. Sirolimus dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, INSULIN, METOPROLOL TARTRATE, RAMIPRIL, ROSIGLITAZONE, RENAGEL, GABAPENTIN, EPOGEN. Patient was hospitalized. Patient died on 04/06/2005.

Sirolimus Side Effects Report #5591636-3
Sirolimus side effect was reported by a Physician from ITALY on Jan 14, 2008. Male patient was diagnosed with prophylaxis against transplant rejection and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: blood creatinine increased, complications of transplanted kidney, renal tubular necrosis. Sirolimus dosage: unknown. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #4717877-2
Sirolimus side effect was reported by a Pharmacist from UNITED STATES on July 18, 2005. Male patient, 55 years of age, weighting 280.0 lb, was diagnosed with immunosuppression, renal transplant, pneumocystis jiroveci pneumonia, prophylaxis and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: angioneurotic oedema, body temperature increased, chills, complications of transplanted kidney, dialysis , petechiae, rash macular. Sirolimus dosage: 5MG ONCE ORAL. During the same period patient was treated with ATOVAQUONE. Patient recovered.

Sirolimus Side Effects Report #5633562-7
Sirolimus side effect was reported by a Health Professional from TURKEY on Feb 07, 2008. Female patient, child 12 years of age, was diagnosed with renal transplant and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: bk virus infection, blood creatinine increased, complications of transplanted kidney, dyspnoea, kidney transplant rejection, pericardial effusion, polyomavirus-associated nephropathy, pyrexia, renal impairment. Sirolimus dosage: unknown. During the same period patient was treated with LEFLUNAMIDE, MYCOPHENOLATE MOFETIL, PREDNISOLONE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.