Sirolimus and complications of transplant surgery Patient Reports February 11, 2012

Sirolimus Side Effects Report #4585939-9
Sirolimus side effect was reported by a Consumer or non-health professional from on Feb 08, 2005. Female patient was diagnosed with renal transplant and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: anaemia, angiopathy, cerebral haemorrhage, complications of transplant surgery, cryptogenic organizing pneumonia, dialysis , nephropathy, oedema peripheral, prothrombin time prolonged. Sirolimus dosage: unknown. During the same period patient was treated with NORVASC. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5410919-0
Sirolimus side effect was reported by a Physician from MEXICO on Aug 07, 2007. Female patient, weighting 132.7 lb, was diagnosed with prophylaxis against transplant rejection, hypertension, hyperuricaemia, hypercholesterolaemia, hyperlipidaemia, gastritis and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: azotaemia, complications of transplant surgery. Sirolimus dosage: unknown. During the same period patient was treated with DILTIAZEM, ENALAPRIL MALEATE, CANDESARTAN CILEXETIL, ALLOPURINOL, MACRODANTIN, PRAVASTATINE, BEZAFIBRATE, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Sirolimus Side Effects Report #5286903-7
Sirolimus side effect was reported by a Physician from NETHERLANDS on Mar 13, 2007. Female patient was diagnosed with immunosuppression and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplant surgery, haemodialysis, haemorrhage, proteinuria, pulmonary embolism , transplant failure. Sirolimus dosage: 6 MG; QD; PO. During the same period patient was treated with METHYLPREDNISOLONE, ORAPRED, MYCOPHENOLATE MOFETIL. Patient recovered.

Sirolimus Side Effects Report #5655336-3
Sirolimus side effect was reported by a Physician from BELGIUM on Feb 26, 2008. Female patient was diagnosed with immunosuppression, type 1 diabetes mellitus and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplant surgery. Sirolimus dosage: LOADING DOSE OF 0.2 MG/KG/DAY AND 0.1 MG/KG/DAY THEREAFTER. During the same period patient was treated with METHYLPREDNISOLONE, INSULIN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient recovered.


Sirolimus Side Effects Report #5655402-2
Sirolimus side effect was reported by a Physician from BELGIUM on Feb 26, 2008. Female patient was diagnosed with immunosuppression, type 1 diabetes mellitus and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplant surgery, lymphocyte count decreased, white blood cell count decreased. Sirolimus dosage: LOADING DOSE OF 0.2 MG/KG/DAY AND 0.1 MG/KG/DAY THEREAFTER. During the same period patient was treated with INSULIN, TACROLIMUS, ANTITHYMOCYTE IMMUNOGLOBULIN, METHYLPREDNISOLONE. Patient recovered.

Sirolimus Side Effects Report #5655404-6
Sirolimus side effect was reported by a Physician from BELGIUM on Feb 26, 2008. Female patient was diagnosed with immunosuppression, type 1 diabetes mellitus and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplant surgery, insulin c-peptide decreased, lymphocyte count decreased, white blood cell count decreased. Sirolimus dosage: LOADING DOSE OF 0.2 MG/KG/DAY AND 0.1 MG/KG/DAY THEREAFTER. During the same period patient was treated with INSULIN, TACROLIMUS, ANTITHYMOCYTE IMMUNOGLOBULIN, METHYLPREDNISOLONE. Patient recovered.

Sirolimus Side Effects Report #5655405-8
Sirolimus side effect was reported by a Physician from BELGIUM on Feb 26, 2008. Female patient was diagnosed with immunosuppression, type 1 diabetes mellitus and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplant surgery, lymphocyte count decreased, white blood cell count decreased. Sirolimus dosage: LOADING DOSE OF 0.2 MG/KG/DAY AND 0.1 MG/KG/DAY THEREAFTER. During the same period patient was treated with METHYLPREDNISOLONE, INSULIN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient recovered.

Sirolimus Side Effects Report #5655416-2
Sirolimus side effect was reported by a Physician from BELGIUM on Feb 26, 2008. Female patient was diagnosed with immunosuppression, type 1 diabetes mellitus and was treated with Sirolimus. After drug was administered, patient experienced the following side effects: complications of transplant surgery. Sirolimus dosage: LOADING DOSE OF 0.2 MG/KG/DAY AND 0.1 MG/KG/DAY THEREAFTER. During the same period patient was treated with METHYLPREDNISOLONE, INSULIN, ANTITHYMOCYTE IMMUNOGLOBULIN. Patient recovered.