Simulect and epstein-barr virus infection Patient Reports February 12, 2012

Simulect Side Effects Report #4822907-3
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, histiocytosis haematophagic, respiratory failure. Simulect dosage: 20 MG INJECTION. During the same period patient was treated with CYCLOSPORINE, CELLCEPT, PREDNISOLONE. Patient died on 01/09/2005.

Simulect Side Effects Report #4829541-X
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, histiocytosis haematophagic, respiratory failure. Simulect dosage: 20 MG INJECTION. During the same period patient was treated with NEORAL, CELLCEPT, PREDNISOLONE. Patient died on 01/09/2005.

Simulect Side Effects Report #4834408-7
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: arthralgia, bone marrow failure, epstein-barr virus infection, histiocytosis haematophagic, platelet count decreased, pyrexia, respiratory failure, serum ferritin increased. Simulect dosage: 20 MG INJECTION. During the same period patient was treated with NEORAL, CELLCEPT, PREDNISOLONE. Patient was hospitalized. Patient died on 01/09/2005.

Simulect Side Effects Report #4841255-9
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: arthralgia, bone marrow failure, epstein-barr virus infection, histiocytosis haematophagic, platelet count decreased, pulmonary haemorrhage, pyrexia, respiratory failure. Simulect dosage: 20 MG INJECTION. During the same period patient was treated with NEORAL, CELLCEPT, PREDNISOLONE. Patient was hospitalized. Patient died on 01/09/2005.


Simulect Side Effects Report #4828759-X
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Female patient, 43 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , epstein-barr virus infection, kidney transplant rejection, nephritis interstitial. Simulect dosage: unknown. During the same period patient was treated with TACROLIMUS, CELLCEPT, METHYLPREDNISOLONE. Patient recovered.

Simulect Side Effects Report #4835126-1
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Female patient, 43 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , epstein-barr virus infection, haematuria, haemodialysis, hydronephrosis, infectious mononucleosis , kidney enlargement, kidney transplant rejection, nephritis interstitial. Simulect dosage: unknown. During the same period patient was treated with TACROLIMUS, CELLCEPT, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Simulect Side Effects Report #5823162-8
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on July 16, 2008. Male patient, 37 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood culture positive, diarrhoea, epstein-barr virus infection, glomerulonephritis membranoproliferative, kidney enlargement, lymphoproliferative disorder, nephrectomy, pyrexia. Simulect dosage: 20 MG, UNK. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE, SIROLIMUS. Patient was hospitalized. Patient recovered.

Simulect Side Effects Report #5839671-1
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on July 29, 2008. Male patient, 37 years of age, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood culture positive, diarrhoea, epstein-barr virus associated lymphoproliferative disorder, epstein-barr virus infection, glomerulonephritis membranoproliferative, kidney enlargement, nephrectomy, pyrexia. Simulect dosage: 20 MG, UNK. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE, SIROLIMUS. Patient was hospitalized. Patient recovered.

Simulect Side Effects Report #5045846-4
Simulect side effect was reported by a Physician from JAPAN on Apr 20, 2006. Male patient, 23 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: candida sepsis, candidiasis, epstein-barr virus infection, histiocytosis haematophagic, incisional drainage, kidney transplant rejection, melaena, pyrexia, removal of renal transplant. Simulect dosage: 20 MG, ONCE/SINGLE. During the same period patient was treated with PROGRAF, CELLCEPT, MEDROL, PREDONINE. Patient died on 12/26/2003.


Simulect Side Effects Report #5393666-3
Simulect side effect was reported by a Physician from JAPAN on July 19, 2007. Male patient, 23 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: candidiasis, epstein-barr virus infection, histiocytosis haematophagic, incisional drainage, intestinal haemorrhage, kidney transplant rejection, malaise, melaena, pyrexia. Simulect dosage: 20 MG, ONCE/SINGLE. During the same period patient was treated with PROGRAF, CELLCEPT, MEDROL, PREDONINE. Patient died on 12/26/2003.

Simulect Side Effects Report #5396398-0
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on July 19, 2007. Male patient, 23 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: candidiasis, epstein-barr virus infection, histiocytosis haematophagic, incisional drainage, intestinal haemorrhage, kidney transplant rejection, malaise, melaena, pyrexia. Simulect dosage: 20 MG, ONCE/SINGLE. During the same period patient was treated with PROGRAF, CELLCEPT, MEDROL, PREDONINE. Patient died on 12/26/2003.

Simulect Side Effects Report #4985048-0
Simulect side effect was reported by a Physician from JAPAN on Apr 20, 2006. Male patient, 23 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: candidiasis, epstein-barr virus infection, histiocytosis haematophagic, incisional drainage, kidney transplant rejection, melaena, pyrexia, removal of renal transplant, sepsis . Simulect dosage: 20 MG, ONCE/SINGLE. During the same period patient was treated with PROGRAF, CELLCEPT, MEDROL, PREDONINE. Patient died on 12/26/2003.

Simulect Side Effects Report #5975684-7
Simulect side effect was reported by a Health Professional from JAPAN on Nov 21, 2008. Male patient was diagnosed with renal transplant, pyelonephritis chronic and was treated with Simulect. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, lymphoproliferative disorder. Simulect dosage: 20 MG, ONCE/SINGLE. During the same period patient was treated with CELLCEPT, NEORAL, PREDNISOLONE. Patient recovered.

Simulect Side Effects Report #5982597-3
Simulect side effect was reported by a Health Professional from JAPAN on Dec 01, 2008. Male patient was diagnosed with renal transplant, pyelonephritis chronic and was treated with Simulect. After drug was administered, patient experienced the following side effects: epstein-barr virus associated lymphoproliferative disorder, epstein-barr virus infection, lymphadenopathy. Simulect dosage: 20 MG, ONCE/SINGLE. During the same period patient was treated with NEORAL, CELLCEPT, PREDNISOLONE. Patient recovered.


Simulect Side Effects Report #5648474-2
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Feb 27, 2008. Female patient, child 1 years of age, was diagnosed with liver and small intestine transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: cholangitis, epstein-barr virus infection, hepatic steatosis, lymphoproliferative disorder, septic shock. Simulect dosage: unknown. During the same period patient was treated with PROGRAF. Patient died.

Simulect Side Effects Report #5657978-8
Simulect side effect was reported by a Consumer or non-health professional from JAPAN on Mar 06, 2008. Female patient, weighting 21.83 lb, was diagnosed with liver and small intestine transplant and was treated with Simulect. After drug was administered, patient experienced the following side effects: cholangitis, epstein-barr virus infection, hepatic steatosis, intestinal villi atrophy, lymphoproliferative disorder, mucosal exfoliation, septic shock. Simulect dosage: unknown. During the same period patient was treated with PROGRAF, STEROIDS NOS. Patient died.