Sebivo and dyspnoea Patient Reports February 13, 2012

Sebivo Side Effects Report #6054531-1
Sebivo side effect was reported by a Physician from CHINA on Jan 20, 2009. Male patient, 22 years of age, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dyspnoea, haemodialysis, heart rate increased, joint swelling, lactic acidosis. Sebivo dosage: 600 MG, QD. During the same period patient was treated with PEGASYS, ENTECAVIR. Patient was hospitalized. Patient recovered.

Sebivo Side Effects Report #6047154-1
Sebivo side effect was reported by a Physician from CHINA on Jan 15, 2009. Male patient, 18 years of age, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, blood creatine phosphokinase increased, blood pressure decreased, blood uric acid increased, cardiac arrest , dysphagia, dyspnoea, endotracheal intubation, hepatic function abnormal. Sebivo dosage: 600 MG, QD. During the same period patient was treated with LAMIVUDINE. Patient was hospitalized. Patient died on 12/29/2008.

Sebivo Side Effects Report #6051836-5
Sebivo side effect was reported by a Physician from CHINA on Jan 21, 2009. Male patient, 18 years of age, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactate dehydrogenase increased, blood pressure decreased, cardiac arrest , dysphagia, dyspnoea, endotracheal intubation, hepatic function abnormal, hepatitis b . Sebivo dosage: 600 MG, QD. During the same period patient was treated with LAMIVUDINE. Patient was hospitalized. Patient died on 12/29/2008.

Sebivo Side Effects Report #6068739-2
Sebivo side effect was reported by a Physician from CHINA on Jan 21, 2009. Male patient, 18 years of age, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactate dehydrogenase increased, blood pressure decreased, cardiac arrest , dysphagia, dyspnoea, endotracheal intubation, hepatic function abnormal, hepatitis b . Sebivo dosage: 600 MG, QD. During the same period patient was treated with LAMIVUDINE. Patient was hospitalized. Patient died on 12/29/2008.


Sebivo Side Effects Report #6086085-8
Sebivo side effect was reported by a Physician from CHINA on Feb 18, 2009. Male patient, 18 years of age, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, blood pressure decreased, cardiac arrest , dysphagia, dyspnoea, endotracheal intubation, hepatic function abnormal. Sebivo dosage: 600 MG, QD. During the same period patient was treated with LAMIVUDINE. Patient was hospitalized. Patient died on 12/29/2008.

Sebivo Side Effects Report #6068301-1
Sebivo side effect was reported by a Physician from CHINA on Feb 01, 2009. Male patient, weighting 132.3 lb, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dyspnoea, haemodialysis, heart rate increased, joint swelling. Sebivo dosage: 600 MG, QD. During the same period patient was treated with PEGASYS, ENTECAVIR. Patient was hospitalized. Patient recovered.

Sebivo Side Effects Report #6079446-4
Sebivo side effect was reported by a Physician from CHINA on Feb 09, 2009. Male patient, weighting 132.3 lb, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dyspnoea, haemodialysis, heart rate increased, joint swelling. Sebivo dosage: 600 MG, QD. During the same period patient was treated with PEGASYS, ENTECAVIR. Patient was hospitalized. Patient recovered.

Sebivo Side Effects Report #6093624-X
Sebivo side effect was reported by a Physician from CHINA on Feb 20, 2009. Male patient, weighting 132.3 lb, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, asthenia, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, dyspnoea, haemodialysis, heart rate increased, joint swelling. Sebivo dosage: 600 MG, QD. During the same period patient was treated with PEGASYS, ENTECAVIR. Patient was hospitalized. Patient recovered.

Sebivo Side Effects Report #6120429-3
Sebivo side effect was reported by a Physician from CHINA on Mar 11, 2009. Male patient, 32 years of age, was treated with Sebivo. After drug was administered, patient experienced the following side effects: abdominal distension, blood creatine phosphokinase increased, blood creatine phosphokinase mb increased, blood pressure decreased, coma, disseminated intravascular coagulation, dyspnoea, gastrointestinal disorder, lactic acidosis. Sebivo dosage: unknown. During the same period patient was treated with HEPSERA, LAMIVUDINE. Patient was hospitalized. Patient died.