Sebivo and blood creatine phosphokinase mb Patient Reports February 12, 2012

Sebivo Side Effects Report #5869917-5
Sebivo side effect was reported by a Physician from CHINA on Aug 27, 2008. Male patient, 20 years of age, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, alpha hydroxybutyrate dehydrogenase increased, aspartate aminotransferase increased, asthenia, blood creatine phosphokinase increased, blood creatine phosphokinase mb, blood immunoglobulin e increased, blood lactate dehydrogenase increased, blood uric acid increased. Sebivo dosage: 600 MG, QD. During the same period patient was treated with PEGASYS. Patient was hospitalized. Patient recovered.

Sebivo Side Effects Report #5840687-X
Sebivo side effect was reported by a Physician from CHINA on Aug 04, 2008. Female patient was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: acidosis, alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood bilirubin increased, blood bilirubin unconjugated increased, blood creatine phosphokinase increased, blood creatine phosphokinase mb, blood lactate dehydrogenase increased. Sebivo dosage: 600 MG QD. Patient was hospitalized. Patient died on 08/04/2008.

Sebivo Side Effects Report #5931963-0
Sebivo side effect was reported by a Physician from CHINA on Oct 21, 2008. Male patient, weighting 130.1 lb, was diagnosed with hepatitis b  and was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, bilirubin conjugated increased, blood bilirubin increased, blood bilirubin unconjugated increased, blood creatine phosphokinase increased, blood creatine phosphokinase mb, blood gases abnormal. Sebivo dosage: 600 MG QD. During the same period patient was treated with LAMIVUDINE. Patient was hospitalized. Patient died on 08/04/2008.

Sebivo Side Effects Report #5782421-8
Sebivo side effect was reported by a Physician from on June 12, 2008. Male patient, 20 years of age, was treated with Sebivo. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, alpha hydroxybutyrate dehydrogenase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood creatine phosphokinase mb, blood immunoglobulin e increased, blood lactate dehydrogenase increased, blood uric acid increased, c-reactive protein increased. Sebivo dosage: unknown. During the same period patient was treated with PEGASYS. Patient was hospitalized. Patient recovered.