Saquinavir and trisomy 21 Patient Reports February 11, 2012

Saquinavir Side Effects Report #5429558-0
Saquinavir side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 17, 2007. Male patient, weighting 4.63 lb, was diagnosed with systemic antiviral treatment and was treated with Saquinavir. After drug was administered, patient experienced the following side effects: atrioventricular septal defect, trisomy 21. Saquinavir dosage: unknown. During the same period patient was treated with NELFINAVIR, FUZEON, ABACAVIR, SUSTIVA, NEVIRAPINE, RITONAVIR. Patient recovered.

Saquinavir Side Effects Report #5459965-1
Saquinavir side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 12, 2007. Male patient, weighting 4.63 lb, was diagnosed with systemic antiviral treatment and was treated with Saquinavir. After drug was administered, patient experienced the following side effects: atrioventricular septal defect, trisomy 21. Saquinavir dosage: unknown. During the same period patient was treated with NELFINAVIR, FUZEON, ABACAVIR, SUSTIVA, NEVIRAPINE, RITONAVIR. Patient recovered.

Saquinavir Side Effects Report #5087796-3
Saquinavir side effect was reported by a Physician from UNITED STATES on Aug 17, 2006. Female patient, 35 years of age, was treated with Saquinavir. After drug was administered, patient experienced the following side effects: trisomy 21. Saquinavir dosage: unknown. During the same period patient was treated with ABACAVIR, NEVIRAPINE, LAMIVUDINE, RITONAVIR. Patient recovered.

Saquinavir Side Effects Report #5464400-3
Saquinavir side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 10, 2007. Male patient, weighting 4.63 lb, was treated with Saquinavir. After drug was administered, patient experienced the following side effects: trisomy 21, unevaluable event. Saquinavir dosage: unknown. During the same period patient was treated with ZIDOVUDINE, LAMIVUDINE, NARCOTICS NOS. Patient recovered.


Saquinavir Side Effects Report #5664664-7
Saquinavir side effect was reported by a Physician from UNITED STATES on Feb 13, 2008. Female patient, weighting 3.97 lb, was diagnosed with hiv infection  and was treated with Saquinavir. After drug was administered, patient experienced the following side effects: arteriovenous malformation , patent ductus arteriosus, pregnancy , trisomy 21. Saquinavir dosage: unknown. During the same period patient was treated with NELFINAVIR, COMBIVIR, RITONAVIR, FOLIC ACID, METRONIDAZOLE, ZANTAC. Patient recovered.