Sandimmune and alanine aminotransferase increased Patient Reports February 11, 2012

Sandimmune Side Effects Report #5712385-4
Sandimmune side effect was reported by a Physician from JAPAN on Apr 15, 2008. Male patient, 62 years of age, weighting 165.3 lb, was diagnosed with stem cell transplant, fungal infection , prophylaxis against graft versus host disease, c-reactive protein increased and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood creatinine increased, blood glucose increased, blood lactate dehydrogenase increased, blood potassium decreased, blood sodium decreased. Sandimmune dosage: 200 MG/D. During the same period patient was treated with AMBISOME, MEROPEN. Patient died on 08/29/2007.

Sandimmune Side Effects Report #5715020-4
Sandimmune side effect was reported by a Physician from JAPAN on Apr 15, 2008. Male patient, 62 years of age, weighting 165.3 lb, was diagnosed with stem cell transplant, fungal infection , prophylaxis against graft versus host disease, c-reactive protein increased and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood creatinine increased, blood glucose increased, blood lactate dehydrogenase increased, blood potassium decreased, blood sodium decreased. Sandimmune dosage: 200 MG/D. During the same period patient was treated with AMBISOME, MEROPEN. Patient died on 08/31/2007.

Sandimmune Side Effects Report #5718539-5
Sandimmune side effect was reported by a Physician from JAPAN on Apr 22, 2008. Male patient, 62 years of age, weighting 165.3 lb, was diagnosed with stem cell transplant, fungal infection , prophylaxis against graft versus host disease, c-reactive protein increased and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood creatinine increased, blood glucose increased, blood lactate dehydrogenase increased, blood potassium decreased, blood sodium decreased. Sandimmune dosage: 200 MG/D. During the same period patient was treated with AMBISOME, MEROPEN. Patient died on 08/29/2007.

Sandimmune Side Effects Report #5522251-5
Sandimmune side effect was reported by a Consumer or non-health professional from CROATIA (local name: Hrvatska) on Nov 13, 2007. Female patient, 57 years of age, weighting 166.4 lb, was diagnosed with renal transplant, hypertension, dyspepsia and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, cytomegalovirus infection , diabetes mellitus, liver injury, movement disorder , muscular weakness. Sandimmune dosage: 2000 MG/DAY. During the same period patient was treated with CELLCEPT, DECORTIN, NITROFURANTOIN, LACIDIPINE, FUROSEMIDE, CONTROLOC, LESCOL, CORTEF. Patient was hospitalized and became disabled. Patient recovered.


Sandimmune Side Effects Report #5522254-0
Sandimmune side effect was reported by a Consumer or non-health professional from CROATIA (local name: Hrvatska) on Nov 13, 2007. Female patient, 57 years of age, weighting 166.4 lb, was diagnosed with renal transplant, hypertension, dyspepsia and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, cytomegalovirus infection , diabetes mellitus, liver injury, movement disorder , muscular weakness. Sandimmune dosage: 2000 MG/DAY. During the same period patient was treated with CELLCEPT, DECORTIN, NITROFURANTOIN, LACIDIPINE, FUROSEMIDE, CONTROLOC, LESCOL, CORTEF. Patient was hospitalized and became disabled. Patient recovered.

Sandimmune Side Effects Report #5144112-6
Sandimmune side effect was reported by a Consumer or non-health professional from JAPAN on Sept 20, 2006. Male patient, 29 years of age, was diagnosed with renal transplant and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatinine increased, haemodialysis, hepatic function abnormal, hepatitis , kidney transplant rejection, oliguria, renal tubular necrosis. Sandimmune dosage: unknown. During the same period patient was treated with NEORAL, SIMULECT, ENDOXAN, PREDNISOLONE, BREDININ, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #4781443-3
Sandimmune side effect was reported by a Physician from JAPAN on Aug 25, 2005. Male patient, 33 years of age, weighting 198.4 lb, was diagnosed with psoriasis and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood sodium decreased, gamma-glutamyltransferase increased, liver function test abnormal. Sandimmune dosage: 200 MG - 250 MG/DAY. During the same period patient was treated with FULMETA, RINDERON. Patient recovered.

Sandimmune Side Effects Report #4791774-9
Sandimmune side effect was reported by a Physician from JAPAN on Aug 25, 2005. Male patient, 33 years of age, weighting 198.4 lb, was diagnosed with psoriasis and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, gamma-glutamyltransferase increased, liver function test abnormal. Sandimmune dosage: 200 MG - 250 MG/DAY. During the same period patient was treated with FULMETA, RINDERON. Patient recovered.

Sandimmune Side Effects Report #5528685-7
Sandimmune side effect was reported by a Consumer or non-health professional from JAPAN on Nov 15, 2007. Male patient, 24 years of age, weighting 151.2 lb, was diagnosed with psoriasis and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, cytomegalovirus antigen positive, cytomegalovirus hepatitis, epstein-barr virus infection, fatigue, hepatic function abnormal, hepatomegaly. Sandimmune dosage: 150 MG/DAY. During the same period patient was treated with MYSER, DERMOVATE, BONALFA, AZELASTINE. Patient was hospitalized. Patient recovered.


Sandimmune Side Effects Report #5774321-4
Sandimmune side effect was reported by a Health Professional from ITALY on June 05, 2008. Female patient was diagnosed with psoriasis, hyperpyrexia and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, gamma-glutamyltransferase increased, hepatitis acute, hyperpyrexia, jaundice , pruritus. Sandimmune dosage: unknown. During the same period patient was treated with TACHIPIRINA, PSORCUTAN, CALOMEL. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #6119831-5
Sandimmune side effect was reported by a Pharmacist from GERMANY on Mar 05, 2009. Female patient was diagnosed with pancytopenia and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, angina pectoris, aspartate aminotransferase increased, chest pain , dizziness , liver function test abnormal, oesophageal spasm, pericardial effusion, stomatitis. Sandimmune dosage: 100 MG, BID. During the same period patient was treated with CALCIUM, MAGNESIUM SULPHATE. Patient recovered.

Sandimmune Side Effects Report #5255107-6
Sandimmune side effect was reported by a Pharmacist from JAPAN on Feb 20, 2007. Female patient, child 7 years of age, was diagnosed with myelodysplastic syndrome and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood glucose increased, convulsion, hypermagnesaemia. Sandimmune dosage: 40 MG/D. Patient recovered.

Sandimmune Side Effects Report #5254311-0
Sandimmune side effect was reported by a Physician from GERMANY on Feb 22, 2007. Male patient, 62 years of age, weighting 149.9 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, bile duct stenosis, bile duct stent insertion, blood alkaline phosphatase increased, cholangitis, gamma-glutamyltransferase increased. Sandimmune dosage: unknown. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5276745-0
Sandimmune side effect was reported by a Physician from GERMANY on Mar 15, 2007. Male patient, 62 years of age, weighting 149.9 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, bile duct stenosis, bile duct stent insertion, biliary ischaemia, blood alkaline phosphatase increased, cholangitis, gamma-glutamyltransferase increased, renal failure. Sandimmune dosage: unknown. Patient was hospitalized. Patient recovered.


Sandimmune Side Effects Report #5327223-1
Sandimmune side effect was reported by a Physician from GERMANY on Mar 29, 2007. Male patient, 62 years of age, weighting 149.9 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, bile duct stenosis, bile duct stent insertion, biliary ischaemia, blood alkaline phosphatase increased, cholangitis, gamma-glutamyltransferase increased, renal failure. Sandimmune dosage: unknown. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5389451-9
Sandimmune side effect was reported by a Physician from GERMANY on July 12, 2007. Male patient, 60 years of age, weighting 154.3 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, neuroendocrine carcinoma, rash , ultrasound liver abnormal. Sandimmune dosage: 200 MG/DAILY. During the same period patient was treated with METHYLPREDNISOLONE. Patient was hospitalized. Patient died on 04/23/2007.

Sandimmune Side Effects Report #5389738-X
Sandimmune side effect was reported by a Physician from GERMANY on July 12, 2007. Male patient, 60 years of age, weighting 154.3 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, neuroendocrine carcinoma, rash , ultrasound liver abnormal. Sandimmune dosage: 200 MG/DAILY. During the same period patient was treated with METHYLPREDNISOLONE. Patient was hospitalized. Patient died on 04/23/2007.

Sandimmune Side Effects Report #5228551-0
Sandimmune side effect was reported by a Physician from GERMANY on Jan 23, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic enzyme increased, hepatitis c virus. Sandimmune dosage: 500 MG, BID. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5238298-2
Sandimmune side effect was reported by a Physician from GERMANY on Feb 06, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, bile duct stent insertion, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic enzyme increased. Sandimmune dosage: 500 MG, BID. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.


Sandimmune Side Effects Report #5245111-6
Sandimmune side effect was reported by a Physician from GERMANY on Feb 15, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, bile duct stent insertion, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic enzyme increased. Sandimmune dosage: 500 MG, BID. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5307401-8
Sandimmune side effect was reported by a Physician from GERMANY on Apr 18, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, bile duct stent insertion, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic enzyme increased. Sandimmune dosage: 500 MG, BID. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5307441-9
Sandimmune side effect was reported by a Physician from GERMANY on Apr 18, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, bile duct stent insertion, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic enzyme increased. Sandimmune dosage: 500 MG, BID. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5385029-1
Sandimmune side effect was reported by a Physician from GERMANY on July 05, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, bile duct stent insertion, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic cirrhosis. Sandimmune dosage: 500 MG, BID. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5385123-5
Sandimmune side effect was reported by a Physician from GERMANY on July 05, 2007. Male patient, 48 years of age, weighting 176.4 lb, was diagnosed with liver transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, bile duct stent insertion, cholangitis, cholestasis, disease progression, endoscopic retrograde cholangiopancreatography, hepatic cirrhosis. Sandimmune dosage: 500 MG, BID. Patient was hospitalized. Patient recovered.


Sandimmune Side Effects Report #5634958-X
Sandimmune side effect was reported by a Consumer or non-health professional from JAPAN on Feb 13, 2008. Male patient was diagnosed with histiocytosis haematophagic and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, ascites, aspartate aminotransferase increased, bilirubin conjugated increased, blood bilirubin increased, blood creatinine increased, blood lactate dehydrogenase increased, blood pressure increased. Sandimmune dosage: 3 MG/KG/D. During the same period patient was treated with PREDONINE, ACYCLOVIR, DOBUTAMINE HYDROCHLORIDE, DOBUTAMINE HYDROCHLORIDE, DOPAMINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5634966-9
Sandimmune side effect was reported by a Consumer or non-health professional from JAPAN on Feb 13, 2008. Male patient was diagnosed with histiocytosis haematophagic and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ammonia increased, ascites, aspartate aminotransferase increased, bilirubin conjugated increased, blood bilirubin increased, blood creatinine increased, blood lactate dehydrogenase increased, blood pressure increased. Sandimmune dosage: 3 MG/KG/D. During the same period patient was treated with PREDONINE, ACYCLOVIR, DOBUTAMINE HYDROCHLORIDE, DOBUTAMINE HYDROCHLORIDE, DOPAMINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5688604-X
Sandimmune side effect was reported by a Consumer or non-health professional from JAPAN on Mar 18, 2008. Male patient, 55 years of age, was diagnosed with bone marrow transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, cholecystitis, continuous haemodiafiltration, cytomegalovirus infection , gallbladder enlargement, jaundice . Sandimmune dosage: 250 MG/DAY. During the same period patient was treated with PREDONINE. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5688605-1
Sandimmune side effect was reported by a Consumer or non-health professional from JAPAN on Mar 18, 2008. Male patient, 55 years of age, was diagnosed with bone marrow transplant  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, cholecystitis, continuous haemodiafiltration, cytomegalovirus infection , gallbladder enlargement, jaundice . Sandimmune dosage: 250 MG/DAY. During the same period patient was treated with PREDONINE. Patient was hospitalized. Patient recovered.

Sandimmune Side Effects Report #5562744-8
Sandimmune side effect was reported by a Physician from JAPAN on Dec 07, 2007. Male patient, child 6 years of age, was treated with Sandimmune. After drug was administered, patient experienced the following side effects: acute hepatic failure, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, hepatic necrosis, pulmonary haemorrhage, pulmonary oedema, pyrexia, respiratory failure. Sandimmune dosage: 3 MG/KG. Patient died.


Sandimmune Side Effects Report #5853695-X
Sandimmune side effect was reported by a Health Professional from FRANCE on Aug 18, 2008. Female patient, 33 years of age, was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anuria, ascites, aspartate aminotransferase increased, blood lactate dehydrogenase increased, blood urea increased, bone marrow toxicity, conjunctival haemorrhage, dialysis . Sandimmune dosage: unknown. During the same period patient was treated with FUROSEMIDE, MORPHINE, CANCIDAS, ZYVOXID, VITAMIN K1, SPASFON, GLYPRESSINE. Patient was hospitalized. Patient died on 06/06/2008.

Sandimmune Side Effects Report #5642854-7
Sandimmune side effect was reported by a Physician from JAPAN on Feb 22, 2008. Male patient, weighting 17.64 lb, was diagnosed with sedation, pneumocystis jiroveci pneumonia, cytomegalovirus infection , fungal infection , bacterial infection  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: acute hepatic failure, alanine aminotransferase increased, aspartate aminotransferase increased, autoimmune disorder, blood alkaline phosphatase increased, blood bilirubin increased, blood glucose increased, blood lactate dehydrogenase increased, blood urea increased. Sandimmune dosage: 23 MG/DAY; 3 MG/KG. During the same period patient was treated with DORMICUM, MIOBLOCK, FENTANYL, BENAMBAX, DENOSINE, FUNGUARD, TAZOCIN, MODACIN. Patient died on 11/23/2007.

Sandimmune Side Effects Report #5648447-X
Sandimmune side effect was reported by a Physician from JAPAN on Feb 28, 2008. Male patient, weighting 17.64 lb, was diagnosed with sedation, pneumocystis jiroveci pneumonia, cytomegalovirus infection , fungal infection , bacterial infection  and was treated with Sandimmune. After drug was administered, patient experienced the following side effects: acute hepatic failure, alanine aminotransferase increased, aspartate aminotransferase increased, autoimmune disorder, blood alkaline phosphatase increased, blood bilirubin increased, blood glucose increased, blood lactate dehydrogenase increased, blood urea increased. Sandimmune dosage: 23 MG/DAY; 3 MG/KG. During the same period patient was treated with DORMICUM, MIOBLOCK, FENTANYL, BENAMBAX, DENOSINE, FUNGUARD, TAZOCIN, MODACIN. Patient died on 11/23/2007.

Sandimmune Side Effects Report #5868809-5
Sandimmune side effect was reported by a Physician from UNITED STATES on Sept 02, 2008. Female patient, weighting 164.2 lb, was treated with Sandimmune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood alkaline phosphatase increased, cardiac failure congestive, pleural effusion. Sandimmune dosage: unknown. During the same period patient was treated with PREDNISONE, FOLIC ACID, CARAFATE, MAGNESIUM OXIDE, COLACE, MYCELEX. Patient was hospitalized. Patient recovered.