Rituximab and sepsis Patient Reports February 11, 2012

Rituximab Side Effects Report #5011036-4
Rituximab side effect was reported by a Health Professional from FRANCE on May 10, 2006. Male patient, 70 years of age, weighting 145.5 lb, was diagnosed with rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: condition aggravated, diverticulum, hydrocele, hyperglycaemia, large intestine perforation, peritonitis, sepsis , sigmoiditis. Rituximab dosage: 100 MG, DAYS 1+15, INTRAVENOUS. During the same period patient was treated with PREDNISONE, METHYLPREDNISOLONE, METHOTREXATE, ACIDE FOLIQUE, NAPROXENE, OMEPRAZOLE, RISEDRONIC ACID. Patient was hospitalized. Patient recovered.

Rituximab Side Effects Report #5713059-6
Rituximab side effect was reported by a Physician from UNITED STATES on Apr 01, 2008. Female patient, weighting 180.3 lb, was diagnosed with rheumatoid arthritis , sarcoidosis, pneumonia , sepsis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: chronic obstructive pulmonary disease, ejection fraction decreased, encephalopathy, intracardiac thrombus, multi-organ failure, pneumonia , respiratory failure, sepsis , systemic inflammatory response syndrome. Rituximab dosage: 1000 MG, UNK. During the same period patient was treated with ROCEPHIN, LINEZOLID, CEFTAZIDIME, TAMIFLU. Patient was hospitalized. Patient died on 03/14/2008.

Rituximab Side Effects Report #5975915-3
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Nov 17, 2008. Female patient was diagnosed with rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: abscess , acute abdomen, postoperative wound complication, sepsis . Rituximab dosage: unknown. During the same period patient was treated with SULFASALAZINE, RANTUDIL, OMEPRAZOLE. Patient was hospitalized. Patient died on 10/16/2008.

Rituximab Side Effects Report #5991719-X
Rituximab side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 04, 2008. Female patient, weighting 104.1 lb, was diagnosed with rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 1000 MG, Q2W. Patient died on 11/17/2008.


Rituximab Side Effects Report #6014742-8
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Dec 04, 2008. Female patient was diagnosed with rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: abscess , acute abdomen, postoperative wound complication, sepsis . Rituximab dosage: unknown. During the same period patient was treated with SULFASALAZINE, RANTUDIL, OMEPRAZOLE. Patient was hospitalized. Patient died on 10/16/2008.

Rituximab Side Effects Report #6025661-5
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Dec 19, 2008. Female patient was diagnosed with rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 1000 MG, UNK. During the same period patient was treated with PREDNISOLONE, PLAQUENIL, FOLIC ACID, LANSOPRAZOLE, ALENDRONIC ACID. Patient died on 05/31/2008.

Rituximab Side Effects Report #6047186-3
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Jan 13, 2009. Female patient was diagnosed with rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 1000 MG, UNK. During the same period patient was treated with PREDNISOLONE, PLAQUENIL, FOLIC ACID, LANSOPRAZOLE, ALENDRONIC ACID. Patient died on 05/31/2008.

Rituximab Side Effects Report #6106564-4
Rituximab side effect was reported by a Physician from JAPAN on Feb 26, 2009. Male patient, 24 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis , white blood cell count decreased. Rituximab dosage: 200 MG, UNK. Patient died on 01/01/2000.

Rituximab Side Effects Report #6119771-1
Rituximab side effect was reported by a Physician from JAPAN on Mar 09, 2009. Male patient, 24 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis , white blood cell count decreased. Rituximab dosage: 200 MG, UNK. Patient recovered.


Rituximab Side Effects Report #5418544-2
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Aug 09, 2007. Female patient was diagnosed with pemphigus , rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 375 MG/M2, UNK. During the same period patient was treated with ETANERCEPT. Patient died.

Rituximab Side Effects Report #5421164-7
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Aug 09, 2007. Female patient was diagnosed with pemphigus , rheumatoid arthritis  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 375 MG/M2, UNK. During the same period patient was treated with ETANERCEPT. Patient died.

Rituximab Side Effects Report #5819134-X
Rituximab side effect was reported by a Physician from UNITED KINGDOM on July 07, 2008. Male patient was diagnosed with non-hodgkin's lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 800 MG, UNK. Patient was hospitalized. Patient died on 07/01/2008.

Rituximab Side Effects Report #5094041-1
Rituximab side effect was reported by a Consumer or non-health professional from NETHERLANDS on Aug 15, 2006. Female patient, 53 years of age, was diagnosed with lymphoproliferative disorder and was treated with Rituximab. After drug was administered, patient experienced the following side effects: aspergillosis, disease progression, graft versus host disease, hepatic infection fungal, multi-organ failure, sepsis . Rituximab dosage: 375 MG/M2, 1/WEEK. Patient recovered.

Rituximab Side Effects Report #5829958-0
Rituximab side effect was reported by a Pharmacist from UNITED STATES on July 31, 2008. Female patient, 57 years of age, was diagnosed with lymphoma  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis alcoholic, hyperbilirubinaemia, mental status changes, sepsis . Rituximab dosage: 600 MG ONCE IV. Patient was hospitalized. Patient recovered.


Rituximab Side Effects Report #5815216-7
Rituximab side effect was reported by a Physician from UNITED KINGDOM on July 04, 2008. Female patient was diagnosed with lymphoma  and was treated with Rituximab. After drug was administered, patient experienced the following side effects: multi-organ failure, pneumonia , sepsis . Rituximab dosage: 500 MG, 1/WEEK. During the same period patient was treated with ITRACONAZOL, MAXIPIME, ISEPACIN. Patient was hospitalized. Patient died on 06/17/2008.

Rituximab Side Effects Report #5317200-9
Rituximab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 23, 2007. Male patient, 58 years of age, was diagnosed with liver transplant , immunosuppression and was treated with Rituximab. After drug was administered, patient experienced the following side effects: bone marrow failure, cytomegalovirus infection , pneumocystis jiroveci infection, sepsis . Rituximab dosage: 375 MG/M2, 1/WEEK. During the same period patient was treated with PLASMA EXCHANGE, TACROLIMUS, STEROIDS, MYCOPHENOLATE MOFETIL, PROSTAGLANDIN E, METHYLPREDNISOLONE, PROTEASE INHIBITOR. Patient died.

Rituximab Side Effects Report #5750262-3
Rituximab side effect was reported by a Physician from UNITED KINGDOM on May 15, 2008. Male patient was diagnosed with graft versus host disease and was treated with Rituximab. After drug was administered, patient experienced the following side effects: blood creatinine increased, disseminated intravascular coagulation, febrile neutropenia, pneumonia , sepsis , white blood cell count decreased. Rituximab dosage: 480 MG, 1/WEEK. During the same period patient was treated with MIZORIBINE, CYCLOSPORINE, METFORMIN. Patient was hospitalized. Patient died on 05/11/2008.

Rituximab Side Effects Report #5815220-9
Rituximab side effect was reported by a Physician from UNITED KINGDOM on July 14, 2008. Male patient was diagnosed with graft versus host disease and was treated with Rituximab. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, pneumonia , sepsis . Rituximab dosage: 480 MG, 1/WEEK. During the same period patient was treated with MIZORIBINE, CYCLOSPORINE, METFORMIN. Patient was hospitalized. Patient died on 05/11/2008.

Rituximab Side Effects Report #5731038-X
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Apr 25, 2008. Female patient, weighting 85.98 lb, was diagnosed with extranodal marginal zone b-cell lymphoma (malt type) and was treated with Rituximab. After drug was administered, patient experienced the following side effects: anaemia, gastric haemorrhage, sepsis , thrombocytopenia, tumour haemorrhage. Rituximab dosage: 375 MG/M2, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, CARDIOXANE, PREDNISOLONE. Patient was hospitalized. Patient recovered.


Rituximab Side Effects Report #5488773-0
Rituximab side effect was reported by a Physician from GERMANY on Oct 10, 2007. Male patient was diagnosed with diffuse large b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: colitis, peritonitis, sepsis . Rituximab dosage: 670 MG, UNK. During the same period patient was treated with DEXAMETHASONE, CYTARABINE, CISPLATIN, NEUPOGEN, PANTOPRAZOLE, NEOMYCIN. Patient died on 05/13/2004.

Rituximab Side Effects Report #6061395-9
Rituximab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 19, 2009. Female patient was diagnosed with diffuse large b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: lactic acidosis, sepsis . Rituximab dosage: 700 MG, Q14D. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, PEGFILGRASTIM, PANTOPRAZOLE, COTRIM. Patient was hospitalized. Patient recovered.

Rituximab Side Effects Report #6072381-7
Rituximab side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 26, 2009. Female patient was diagnosed with diffuse large b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: lactic acidosis, sepsis . Rituximab dosage: 700 MG, Q14D. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, PEGFILGRASTIM, PANTOPRAZOLE, COTRIMOXAZOLE. Patient was hospitalized. Patient died on 01/21/2009.

Rituximab Side Effects Report #6128812-7
Rituximab side effect was reported by a Physician from GERMANY on Mar 12, 2009. Female patient was diagnosed with diffuse large b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 375 MG/M2. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, PREDNISONE, DOXORUBICIN. Patient died.

Rituximab Side Effects Report #6130173-4
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Mar 09, 2009. Male patient, 61 years of age, was diagnosed with chronic lymphocytic leukaemia and was treated with Rituximab. After drug was administered, patient experienced the following side effects: neutropenic colitis, renal failure acute, sepsis . Rituximab dosage: 375 MG/M2, UNK. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, BENDAMUSTINE. Patient was hospitalized. Patient died on 03/10/2009.


Rituximab Side Effects Report #5464147-3
Rituximab side effect was reported by a Health Professional from UNITED KINGDOM on Sept 17, 2007. Male patient, weighting 127.9 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 649 MG, QD. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, CLARITHROMYCIN, CEFUROXIME, ENALAPRIL MALEATE, ISOSORBIDE MONONITRATE, TRAMADOL, ALLOPURINOL. Patient was hospitalized. Patient died on 03/03/2006.

Rituximab Side Effects Report #5478225-6
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Sept 26, 2007. Male patient, weighting 178.6 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Rituximab. After drug was administered, patient experienced the following side effects: pneumonia , sepsis . Rituximab dosage: 700 MG, UNK. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.

Rituximab Side Effects Report #5720511-6
Rituximab side effect was reported by a Consumer or non-health professional from GERMANY on Apr 16, 2008. Female patient, weighting 143.3 lb, was diagnosed with chronic lymphocytic leukaemia and was treated with Rituximab. After drug was administered, patient experienced the following side effects: aplasia, cardiovascular insufficiency, pneumonia , respiratory failure, sepsis . Rituximab dosage: 615 MG, Q4W. During the same period patient was treated with BENDAMUSTINE. Patient died on 02/01/2007.

Rituximab Side Effects Report #5478804-6
Rituximab side effect was reported by a Physician from HUNGARY on Sept 28, 2007. Male patient, weighting 238.1 lb, was diagnosed with b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: febrile neutropenia, sepsis . Rituximab dosage: 375 MG/M2, 8/WEEK. Patient was hospitalized. Patient recovered.

Rituximab Side Effects Report #5481780-3
Rituximab side effect was reported by a Physician from HUNGARY on Sept 28, 2007. Male patient, weighting 238.1 lb, was diagnosed with b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: febrile neutropenia, sepsis . Rituximab dosage: 375 MG/M2, 8/WEEK. Patient was hospitalized. Patient recovered.


Rituximab Side Effects Report #5491264-4
Rituximab side effect was reported by a Physician from GERMANY on Oct 12, 2007. Male patient was diagnosed with b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: multi-organ failure, pancytopenia, sepsis . Rituximab dosage: 750 MG, UNK. During the same period patient was treated with ETOPOSIDE, CARBOPLATIN, IFOSFAMIDE, NEUPOGEN. Patient was hospitalized. Patient died on 08/18/2007.

Rituximab Side Effects Report #5527060-9
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Nov 14, 2007. Female patient, weighting 132.1 lb, was diagnosed with b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: myelodysplastic syndrome, pyrexia, sepsis . Rituximab dosage: 800 MG, UNK. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient recovered.

Rituximab Side Effects Report #5677765-4
Rituximab side effect was reported by a Physician from UNITED KINGDOM on Mar 12, 2008. Female patient, weighting 194.0 lb, was diagnosed with b-cell lymphoma and was treated with Rituximab. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, aspiration, bronchopneumonia, cardiac arrest , cytomegalovirus colitis, hypoxia, pneumonia aspiration, sepsis . Rituximab dosage: unknown. Patient recovered.

Rituximab Side Effects Report #4694123-X
Rituximab side effect was reported by a Consumer or non-health professional from on June 16, 2005. Male patient, weighting 131.4 lb, was diagnosed with aids related complication and was treated with Rituximab. After drug was administered, patient experienced the following side effects: abdominal pain , hypotension, neutropenia, sepsis . Rituximab dosage: unknown. During the same period patient was treated with ETOPOSIDE, DOXORUBICIN, VINCRISTINE, CYCLOPHOSPHAMIDE. Patient recovered.

Rituximab Side Effects Report #5989570-X
Rituximab side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 04, 2008. Female patient, weighting 104.1 lb, was treated with Rituximab. After drug was administered, patient experienced the following side effects: sepsis . Rituximab dosage: 1000 MG, Q2W. Patient died on 11/17/2008.


Rituximab Side Effects Report #4946280-5
Rituximab side effect was reported by a Health Professional from UNITED STATES on Mar 16, 2006. Female patient, weighting 118.0 lb, was treated with Rituximab. After drug was administered, patient experienced the following side effects: abdominal pain , febrile neutropenia, large intestine perforation, neoplasm, pelvic abscess, respiratory failure, sepsis . Rituximab dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CYTOXAN, PREDNISONE. Patient was hospitalized. Patient recovered.