Rituxan and hepatic failure Patient Reports February 11, 2012

Rituxan Side Effects Report #4631399-9
Rituxan side effect was reported by a Health Professional from on Mar 24, 2005. Male patient, 64 years of age, weighting 140.0 lb, was diagnosed with waldenstrom's macroglobulinaemia and was treated with Rituxan. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, heart rate increased, hepatic failure, hyperhidrosis, infusion related reaction, platelet count decreased. Rituxan dosage: 680 MG, 1/WEEK, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Rituxan Side Effects Report #4855585-8
Rituxan side effect was reported by a Consumer or non-health professional from JAPAN on Dec 01, 2005. Male patient, 88 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis acute, plasmapheresis, pneumonia , shock. Rituxan dosage: 375 MG/M2, X4, INTRAVENOUS. Patient was hospitalized. Patient died on 08/03/2002.

Rituxan Side Effects Report #4699184-X
Rituxan side effect was reported by a Physician from on June 09, 2005. Male patient, 83 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic atrophy, hepatic failure, hepatitis b . Rituxan dosage: 375 MG/M2, INTRAVENOUS. During the same period patient was treated with PIRARUBICIN, CYCLOPHOSPHAMIDE, ONCOVIN, PREDNISONE. Patient was hospitalized. Patient died on 02/01/2005.

Rituxan Side Effects Report #5499286-4
Rituxan side effect was reported by a Physician from JAPAN on Oct 17, 2007. Female patient, 81 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, intestinal perforation. Rituxan dosage: 500 ML, QD. Patient recovered.


Rituxan Side Effects Report #4923953-1
Rituxan side effect was reported by a Physician from JAPAN on Feb 08, 2006. Female patient, 76 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, bradycardia, dyspnoea, gastrointestinal haemorrhage, hepatic failure, hyperkalaemia, hypotension, oxygen saturation decreased. Rituxan dosage: 500 MG, INTRAVENOUS. During the same period patient was treated with VENA, LOXONIN, LASIX, ALDACTONE, LEVOFLOXACIN, SULFAMETHOXAZOLE, TAGAMET, DIPHENHYDRAMINE. Patient died on 12/06/2005.

Rituxan Side Effects Report #5114962-0
Rituxan side effect was reported by a Health Professional from JAPAN on Sept 08, 2006. Male patient, 74 years of age, weighting 224.9 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: fibrin increased, haemodialysis, haemoglobin decreased, hepatic encephalopathy, hepatic failure, hepatitis b , monocyte percentage increased, red blood cell count decreased, renal failure. Rituxan dosage: 800 MG, INTRAVENOUS. During the same period patient was treated with ENDOXAN, ETOPOSIDE, DECADRON, ALKERAN. Patient died on 06/21/2006.

Rituxan Side Effects Report #4671125-0
Rituxan side effect was reported by a Health Professional from on May 10, 2005. Female patient, 74 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: flatulence, hepatic failure, melaena, tremor. Rituxan dosage: 470 MG INTRAVENOUS. During the same period patient was treated with KIROSIDE, SACSIZONE. Patient died on 10/25/2003.

Rituxan Side Effects Report #4719167-0
Rituxan side effect was reported by a Health Professional from JAPAN on July 07, 2005. Female patient, 73 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, flatulence, hepatic failure, jaundice , malaise, melaena, tremor. Rituxan dosage: 470 MG, INTRAVENOUS. During the same period patient was treated with KIROSIDE, SACSIZONE. Patient died on 10/25/2003.

Rituxan Side Effects Report #4743567-6
Rituxan side effect was reported by a Health Professional from JAPAN on July 25, 2005. Female patient, 73 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, melaena, tremor. Rituxan dosage: 470 MG, INTRAVENOUS. During the same period patient was treated with SAXIZON, CHLOR, ACEBUTOLOL HYDROCHLORIDE, FAMOTIDINE, CYCLOCIDE. Patient died on 10/25/2003.


Rituxan Side Effects Report #5218509-X
Rituxan side effect was reported by a Health Professional from JAPAN on Jan 10, 2007. Male patient, 68 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure. Rituxan dosage: unknown. During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, ONCOVIN, PREDNISOLONE. Patient died.

Rituxan Side Effects Report #5244826-3
Rituxan side effect was reported by a Physician from JAPAN on Feb 05, 2007. Male patient, 68 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure. Rituxan dosage: unknown. During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, ONCOVIN, PREDNISOLONE. Patient died.

Rituxan Side Effects Report #5273347-7
Rituxan side effect was reported by a Physician from JAPAN on Mar 04, 2007. Male patient, 68 years of age, weighting 152.1 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: anaemia, gastric ulcer, gastrointestinal haemorrhage, helicobacter infection, hepatic failure, tumour lysis syndrome. Rituxan dosage: 375 MG, QD, INTRAVENOUS. During the same period patient was treated with FERROMIA, LASIX, ALDACTONE, URSO, OCTOTIAMINE, ASPARA, CHINESE MEDICINE, MOSAPRIDE CITRATE. Patient recovered.

Rituxan Side Effects Report #5087212-1
Rituxan side effect was reported by a Physician from JAPAN on Aug 08, 2006. Female patient, 68 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: disease recurrence, fungal sepsis, hepatic atrophy, hepatic cirrhosis, hepatic failure, hepatitis b , prothrombin time prolonged. Rituxan dosage: 500 MG, INTRAVENOUS. During the same period patient was treated with FLUDARA, MITOXANTRONE, DEXAMETHASONE, NEUPOGEN. Patient died on 11/12/2002.

Rituxan Side Effects Report #4839926-3
Rituxan side effect was reported by a Physician from JAPAN on Nov 11, 2005. Male patient, 68 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, depressed level of consciousness, heart rate decreased, hepatic failure, po2 decreased, renal failure. Rituxan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ADRIAMYCIN PFS, ONCOVIN, PREDONINE, NARTOGRASTIM, DALTEPARIN. Patient died on 08/31/2005.


Rituxan Side Effects Report #4868783-4
Rituxan side effect was reported by a Physician from JAPAN on Dec 19, 2005. Male patient, 68 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, depressed level of consciousness, heart rate decreased, hepatic failure, infusion related reaction, renal failure, respiratory failure. Rituxan dosage: 375 MG/M2, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, ONCOVIN, PREDONINE, NARTOGRASTIM, DALTEPARIN. Patient died on 08/31/2005.

Rituxan Side Effects Report #4761077-7
Rituxan side effect was reported by a Physician from JAPAN on Aug 18, 2005. Female patient, 62 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b . Rituxan dosage: 680 MG, INTRAVENOUS. During the same period patient was treated with LEUSTATIN, VOLTAREN, MEQUITAZINE, COTRIM, FAMOTIDINE, URSODIOL. Patient died on 04/15/2005.

Rituxan Side Effects Report #4775007-5
Rituxan side effect was reported by a Physician from JAPAN on Sept 16, 2005. Female patient, 62 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: anti-hbc igg antibody positive, hepatic failure, hepatitis b . Rituxan dosage: 680 MG,UNK, INTRAVENOUS. During the same period patient was treated with LEUSTATIN, VOLTAREN, MEQUITAZINE, COTRIM, FAMOTIDINE, URSODIOL. Patient died on 04/15/2005.

Rituxan Side Effects Report #4810035-2
Rituxan side effect was reported by a Physician from JAPAN on Oct 14, 2005. Female patient, 62 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b , hepatitis c antibody positive, malaise. Rituxan dosage: 680 MG, INTRAVENOUS. During the same period patient was treated with LEUSTATIN, VOLTAREN, MEQUITAZINE, COTRIM, FAMOTIDINE, URSODIOL, GLUTATHIONE, GYCEROPHOSPHORIC ACID. Patient died on 04/15/2005.

Rituxan Side Effects Report #4810393-9
Rituxan side effect was reported by a Physician from JAPAN on Oct 14, 2005. Female patient, 62 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, ascites, asterixis, chromaturia, disease recurrence, foetor hepaticus, hepatic failure, hepatitis b . Rituxan dosage: 680 MG, INTRAVENOUS. During the same period patient was treated with LEUSTATIN, VOLTAREN, MEQUITAZINE, COTRIM, FAMOTIDINE, URSODIOL, GLUTATHIONE, GLYCEROPHOSPHORIC ACID. Patient died on 04/15/2005.


Rituxan Side Effects Report #4902356-X
Rituxan side effect was reported by a Physician from JAPAN on Jan 20, 2006. Male patient, 61 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure. Rituxan dosage: 563 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, BLOOD TRANSFUSION, POLARAMINE, KYTRIL. Patient died.

Rituxan Side Effects Report #4765776-2
Rituxan side effect was reported by a Physician from JAPAN on Aug 22, 2005. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure. Rituxan dosage: 375 MG/M2, INTRAVENOUS. Patient died.

Rituxan Side Effects Report #4783672-1
Rituxan side effect was reported by a Physician from JAPAN on Sept 23, 2005. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure. Rituxan dosage: 375MG/M2, INTRAVENOUS. Patient died.

Rituxan Side Effects Report #4847730-5
Rituxan side effect was reported by a Physician from JAPAN on Nov 22, 2005. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: blood creatinine increased, hepatic failure, liver disorder. Rituxan dosage: 563 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, BLOOD TRANSFUSION, POLARAMINE, KYTRIL. Patient died on 12/05/2003.

Rituxan Side Effects Report #5605962-2
Rituxan side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 22, 2008. Female patient, 80 years of age, was diagnosed with mantle cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis . Rituxan dosage: unknown. Patient recovered.


Rituxan Side Effects Report #4572976-3
Rituxan side effect was reported by a Physician from on Jan 21, 2005. Female patient, 75 years of age, was diagnosed with lymphoma  and was treated with Rituxan. After drug was administered, patient experienced the following side effects: depressed level of consciousness, hepatic encephalopathy, hepatic failure, hyperammonaemia, somnolence. Rituxan dosage: unknown. During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, VINCRISTINE, PREDNISONE, CYTARABINE, BLEOMYCIN, METHOTREXATE. Patient recovered.

Rituxan Side Effects Report #4822609-3
Rituxan side effect was reported by a Physician from JAPAN on Oct 25, 2005. Female patient, 75 years of age, was diagnosed with lymphoma  and was treated with Rituxan. After drug was administered, patient experienced the following side effects: depressed level of consciousness, hepatic encephalopathy, hepatic failure, hyperammonaemia, lymphoma , recurrent cancer, somnolence. Rituxan dosage: 500 MG INTRAVENOUS. During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, VINCRISTINE, PREDNISONE, CYTARABINE, BLEOMYCIN, METHOTREXATE, BLOOD TRANSFUSION NOS. Patient recovered.

Rituxan Side Effects Report #4791834-2
Rituxan side effect was reported by a Physician from JAPAN on Sept 20, 2005. Male patient, 51 years of age, was diagnosed with idiopathic thrombocytopenic purpura, pneumonia bacterial and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, liver disorder, multi-organ failure, nocardiosis, pneumonia bacterial, pneumonia fungal, respiratory failure. Rituxan dosage: 700 MG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with SULFAMETHOXAZOLE, URSODIOL, LIVACT, GLYCYRON #, PREDNISONE. Patient was hospitalized. Patient recovered.

Rituxan Side Effects Report #4830718-8
Rituxan side effect was reported by a Physician from JAPAN on Nov 02, 2005. Male patient, 51 years of age, was diagnosed with idiopathic thrombocytopenic purpura and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, liver disorder, multi-organ failure, nocardiosis, pneumonia bacterial, pneumonia fungal, respiratory disorder. Rituxan dosage: 700 MG, 1 WEEK, INTRAVENOUS. During the same period patient was treated with URSODIOL, LIVACT, GLYCYRON #, PREDNISONE. Patient was hospitalized. Patient recovered.

Rituxan Side Effects Report #4839892-0
Rituxan side effect was reported by a Physician from JAPAN on Nov 02, 2005. Male patient, 51 years of age, was diagnosed with idiopathic thrombocytopenic purpura and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, multi-organ failure, nocardiosis, pneumonia bacterial, pneumonia fungal, respiratory disorder. Rituxan dosage: 700 MG, 1/WEEK, INTRAVENOUS. During the same period patient was treated with URSODIOL, GLYCYRON #, PREDNISONE. Patient was hospitalized. Patient recovered.


Rituxan Side Effects Report #4815707-1
Rituxan side effect was reported by a Physician from JAPAN on Oct 14, 2005. Male patient, 73 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: anti-hbc antibody positive, atrial fibrillation , cardiac disorder, coma, duodenal ulcer perforation, hepatic encephalopathy, hepatic failure, hepatitis b , multi-organ failure. Rituxan dosage: 480 MG, INTRAVENOUS. During the same period patient was treated with PIRARUBICIN, CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, PREDNISOLONE, ANTIBIOTICS NOS, ANTIFUNGAL AGENTS, VASOPRESSOR, STEROIDS NOS. Patient died on 11/09/2004.

Rituxan Side Effects Report #4819823-X
Rituxan side effect was reported by a Physician from JAPAN on Oct 19, 2005. Male patient, 73 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: atrial fibrillation , duodenal ulcer perforation, hepatic encephalopathy, hepatic failure, hepatic function abnormal, hepatitis b , infection , multi-organ failure, pneumonia aspiration. Rituxan dosage: 480 MG, INTRAVENOUS. During the same period patient was treated with PIRARUBICIN, CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, PREDNISONE, ANTIBIOTICS NOS, ANTIFUNGAL AGENTS, VASOPRESSOR, STEROIDS NOS. Patient died on 11/09/2004.

Rituxan Side Effects Report #5467611-6
Rituxan side effect was reported by a Physician from JAPAN on Sept 16, 2007. Male patient, 54 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b . Rituxan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, ETOPOSIDE, IFOSFAMIDE, METHOTREXATE. Patient died.

Rituxan Side Effects Report #5503269-5
Rituxan side effect was reported by a Physician from JAPAN on Oct 22, 2007. Male patient, 54 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b . Rituxan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, ETOPOSIDE, IFOSFAMIDE, METHOTREXATE. Patient died.

Rituxan Side Effects Report #5510477-6
Rituxan side effect was reported by a Physician from JAPAN on Nov 01, 2007. Male patient, 54 years of age, was diagnosed with diffuse large b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b . Rituxan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, ETOPOSIDE, IFOSFAMIDE, METHOTREXATE. Patient died.


Rituxan Side Effects Report #4633167-0
Rituxan side effect was reported by a Consumer or non-health professional from on Apr 11, 2005. Female patient, 71 years of age, was diagnosed with b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: back pain , dental caries, disseminated intravascular coagulation, fall , groin pain, hepatic failure, hepatic trauma, hepatitis . Rituxan dosage: unknown. During the same period patient was treated with ASPIRIN, FERROUS SULPHATE, VIOXX, VICODIN, DIGOXIN, LIPITOR, ISOSORBIDE, LEXAPRO. Patient was hospitalized. Patient died on 06/25/2004.

Rituxan Side Effects Report #5288854-0
Rituxan side effect was reported by a Consumer or non-health professional from FRANCE on Mar 28, 2007. Female patient, 68 years of age, weighting 178.1 lb, was diagnosed with b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: cardiac failure, gastrointestinal necrosis, hepatic failure, neutropenia, renal failure acute, septic shock. Rituxan dosage: 690 MG, UNK. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rituxan Side Effects Report #4967129-0
Rituxan side effect was reported by a Health Professional from UNITED STATES on Mar 22, 2006. Male patient, 21 years of age, was diagnosed with b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: blood immunoglobulin m decreased, coma, hepatic failure, hepatitis b , pneumonia respiratory syncytial viral. Rituxan dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, PREDNISONE. Patient died.

Rituxan Side Effects Report #5522626-4
Rituxan side effect was reported by a Physician from CANADA on Nov 08, 2007. Female patient was diagnosed with b-cell lymphoma and was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure. Rituxan dosage: unknown. Patient died.

Rituxan Side Effects Report #4802139-5
Rituxan side effect was reported by a Physician from UNITED STATES on Sept 29, 2005. Female patient, 21 years of age, was diagnosed with anaemia haemolytic autoimmune and was treated with Rituxan. After drug was administered, patient experienced the following side effects: brain oedema, cerebral haemorrhage, cholestasis, hepatic failure, hepatic haemorrhage, hepatic necrosis, hepatic steatosis, hepatomegaly, respiratory distress. Rituxan dosage: 375 MG/M2, 1/WEEK, INTRAVENOUS. During the same period patient was treated with TACROLIMUS, CASPOFUNGIN, VALACYCLOVIR, PREVACID, URSODIOL, MAGNESIUM OXIDE. Patient died.


Rituxan Side Effects Report #4659809-1
Rituxan side effect was reported by a Physician from on Apr 26, 2005. Male patient, 83 years of age, was treated with Rituxan. After drug was administered, patient experienced the following side effects: hepatic failure, hepatitis b . Rituxan dosage: unknown. During the same period patient was treated with PIRARUBICIN, CYCLOPHOSPHAMIDE, ONCOVIN, PREDNISONE. Patient died on 02/01/2005.