Rheumatrex and bone marrow depression Patient Reports February 11, 2012

Rheumatrex Side Effects Report #4545294-7
Rheumatrex side effect was reported by a Consumer or non-health professional from on Dec 21, 2004. Female patient, 82 years of age, was diagnosed with rheumatoid arthritis  and was treated with Rheumatrex. After drug was administered, patient experienced the following side effects: bone marrow depression, fungal infection , pleural effusion, pneumonia , septic shock, staphylococcal infection , stomatitis. Rheumatrex dosage: unknown. During the same period patient was treated with BONALON, MINOCYCLINE, VOLTAREN. Patient was hospitalized. Patient died.

Rheumatrex Side Effects Report #4714295-8
Rheumatrex side effect was reported by a Consumer or non-health professional from JAPAN on June 30, 2005. Female patient, 82 years of age, was diagnosed with rheumatoid arthritis  and was treated with Rheumatrex. After drug was administered, patient experienced the following side effects: bone marrow depression, fungal infection , pleural effusion, pneumonia , septic shock, staphylococcal infection , stomatitis. Rheumatrex dosage: unknown. During the same period patient was treated with MINOCYCLINE, VOLTAREN, PREDNISONE, STARLIX, COTRIM, FAMOTIDINE. Patient was hospitalized. Patient died.

Rheumatrex Side Effects Report #4743962-5
Rheumatrex side effect was reported by a Consumer or non-health professional from JAPAN on July 27, 2005. Female patient, 82 years of age, was diagnosed with rheumatoid arthritis  and was treated with Rheumatrex. After drug was administered, patient experienced the following side effects: bone marrow depression, fungal infection , pleural effusion, pneumonia , septic shock, staphylococcal infection , stomatitis. Rheumatrex dosage: 2 + 4 + 6 + 8 MG 1X PER 1 WK ORAL - SEE IMAGE. During the same period patient was treated with MINOCYCLINE, VOLTAREN, PREDNISONE, STARLIX, COTRIM, FAMOTIDINE, SIGMART. Patient was hospitalized. Patient died.

Rheumatrex Side Effects Report #4617697-3
Rheumatrex side effect was reported by a Consumer or non-health professional from on Mar 11, 2005. Female patient, 75 years of age, was treated with Rheumatrex. After drug was administered, patient experienced the following side effects: blood urea increased, bone marrow depression, c-reactive protein increased, cardiac arrest , cardiomegaly, cytomegalovirus infection , diarrhoea, dyspnoea, gastrointestinal disorder. Rheumatrex dosage: 2 MG WEEKLY, PO; 2 MG WEEKLY, PO; 4 MG WEEKLY, PO; 6 MG WEEKLY, PO. During the same period patient was treated with METHYLPREDNISOLONE, MISOPROSTOL, ROXATIDINE ACETATE, CALCITRIOL. Patient was hospitalized. Patient died on 08/03/2003.