Rasburicase and dyspnoea Patient Reports February 12, 2012

Rasburicase Side Effects Report #4640183-1
Rasburicase side effect was reported by a Health Professional from on Apr 14, 2003. Female patient, 57 years of age, was diagnosed with hyperuricaemia, non-hodgkin's lymphoma and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood potassium decreased, bronchospasm, chills, dyspnoea, haemoglobin decreased, hyperthermia, hypotension. Rasburicase dosage: 10.5 MG INTRAVENOUS NOS. During the same period patient was treated with LYSANXIA, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.

Rasburicase Side Effects Report #4582433-6
Rasburicase side effect was reported by a Physician from on Jan 21, 2005. Male patient, 44 years of age, weighting 207.2 lb, was diagnosed with hyperuricaemia, tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: alanine aminotransferase decreased, aspartate aminotransferase increased, blood fibrinogen increased, blood lactate dehydrogenase increased, confusional state, dyspnoea, gamma-glutamyltransferase increased, liver function test abnormal. Rasburicase dosage: 0.2 MG/KG QD - INTRAVENOUS NOS. During the same period patient was treated with ALLOPURINOL, CYTARABINE, MITOXANTRONE, PIPERACILLIN, GENTAMICIN, CEFTAZIDIME, VANCOMYCIN. Patient recovered.

Rasburicase Side Effects Report #4903714-X
Rasburicase side effect was reported by a Health Professional from UNITED STATES on Jan 21, 2005. Male patient, weighting 207.2 lb, was diagnosed with hyperuricaemia and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anti-hbs antibody positive, aspartate aminotransferase increased, blood lactate dehydrogenase increased, confusional state, cough, dyspnoea, liver function test abnormal, muscle twitching. Rasburicase dosage: unknown. During the same period patient was treated with ALLOPURINOL, CYTARABINE, MITOXANTRONE, ZOSYN, GENTAMICIN, FORTAZ, VANCOMYCIN, ACYCLOVIR. Patient recovered.

Rasburicase Side Effects Report #4565649-4
Rasburicase side effect was reported by a Pharmacist from on Jan 25, 2005. Male patient, 58 years of age, weighting 229.3 lb, was diagnosed with blood uric acid increased, prophylaxis, tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood creatinine increased, dyspnoea, methaemoglobinaemia, oxygen saturation decreased, po2 increased, tumour lysis syndrome. Rasburicase dosage: 15MG Q DAY INTRAVENOUS. During the same period patient was treated with DOXORUBICIN, CISPLATIN, CYTARABINE, DEXAMETHASONE, ALLOPURINOL, DOCUSATE. Patient recovered.


Rasburicase Side Effects Report #4619117-1
Rasburicase side effect was reported by a Health Professional from on Apr 14, 2003. Female patient, weighting 121.3 lb, was treated with Rasburicase. After drug was administered, patient experienced the following side effects: bronchospasm, dyspnoea, hyperthermia, hypotension. Rasburicase dosage: 10.5 MG. During the same period patient was treated with LYSANXIA, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.

Rasburicase Side Effects Report #4624808-2
Rasburicase side effect was reported by a Health Professional from on Apr 14, 2003. Female patient, weighting 121.3 lb, was treated with Rasburicase. After drug was administered, patient experienced the following side effects: bronchospasm, chills, dyspnoea, hyperthermia, hypotension. Rasburicase dosage: 10.5 MG. During the same period patient was treated with LYSANXIA, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.