Rapamune and thrombocytopenia Patient Reports February 11, 2012

Rapamune Side Effects Report #5737688-9
Rapamune side effect was reported by a Health Professional from SWITZERLAND on May 09, 2008. Male patient, 26 years of age, was diagnosed with stem cell transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood lactate dehydrogenase increased, disease progression, kidney fibrosis, renal failure, thrombocytopenia, thrombotic microangiopathy. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE, CELLCEPT, COVERSUM, DIFLUCAN, BACTRIM, FAMVIR, PANTOPRAZOLE, TACROLIMUS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4988126-5
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on Apr 13, 2006. Male patient, 50 years of age, was diagnosed with renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: ischaemia, leukopenia, renal failure acute, thrombocytopenia, ureteric stenosis. Rapamune dosage: unknown. During the same period patient was treated with BACTRIM, CELLCEPT, VALACYCLOVIR. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5939752-8
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 31, 2008. Female patient, 41 years of age, weighting 240.0 lb, was diagnosed with renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: multi-organ failure, pulmonary fibrosis , respiratory failure, thrombocytopenia. Rapamune dosage: 1 MG 2 PER DAY PO. Patient died on 01/04/2007.

Rapamune Side Effects Report #4839214-5
Rapamune side effect was reported by a Physician from UNITED STATES on Oct 08, 2004. Male patient was diagnosed with renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: condition aggravated, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #5897694-0
Rapamune side effect was reported by a Physician from FRANCE on Sept 22, 2008. Male patient, 67 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: leukopenia, overdose, rectal haemorrhage, thrombocytopenia. Rapamune dosage: unknown. During the same period patient was treated with WARFARIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4640230-7
Rapamune side effect was reported by a Consumer or non-health professional from on Apr 06, 2005. Female patient, 63 years of age, weighting 160.9 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, kidney transplant rejection, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with PREDNISONE, PROGRAF, PREMARIN, LEVOTHYROXINE, BICARBONATE IN PLASTIC CONTAINER, LEVOBUNOLOL, SEPTRA DS, VALCYTE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4840338-7
Rapamune side effect was reported by a Pharmacist from UNITED STATES on Jan 27, 2005. Male patient, 60 years of age, weighting 165.1 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: influenza like illness, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY,ORAL. During the same period patient was treated with TACROLIMUS, MYCOPHENOLATE MOFETIL, PRENDISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4875863-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 27, 2005. Male patient, 59 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, dialysis , fluid overload, hyperkalaemia, oliguria, renal tubular necrosis, thrombocytopenia. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ZENAPAX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4960394-5
Rapamune side effect was reported by a Physician from SPAIN on Mar 17, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, gastrointestinal haemorrhage, nephrolithiasis, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4975598-5
Rapamune side effect was reported by a Health Professional from SPAIN on Apr 03, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, complications of transplanted kidney, gastrointestinal disorder, gastrointestinal haemorrhage, ill-defined disorder, nephrocalcinosis, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4978339-0
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Apr 06, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, complications of transplanted kidney, gastrointestinal haemorrhage, nephrocalcinosis, renal tubular necrosis, small intestinal haemorrhage, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4998578-2
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Apr 24, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, gastrointestinal haemorrhage, haemodialysis, nephrocalcinosis, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5046908-8
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on June 27, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: abscess , bone marrow toxicity, gastrointestinal haemorrhage, haemodialysis, nephrocalcinosis, procedural site reaction, renal tubular necrosis, thrombocytopenia, transplant rejection. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4818873-7
Rapamune side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 18, 2005. Female patient, 49 years of age, was diagnosed with prophylaxis against transplant rejection, arthralgia and was treated with Rapamune. After drug was administered, patient experienced the following side effects: leukopenia, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY. During the same period patient was treated with AZATHIOPRINE, HYDROXYCHLOROQUINE, RISEDRONATE, ATORVASTATIN CALCIUM, CEPHRADINE. Patient recovered.


Rapamune Side Effects Report #4907385-8
Rapamune side effect was reported by a Health Professional from UNITED KINGDOM on Feb 01, 2006. Female patient, 49 years of age, was diagnosed with prophylaxis against transplant rejection, arthralgia and was treated with Rapamune. After drug was administered, patient experienced the following side effects: leukopenia, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. During the same period patient was treated with AZATHIOPRINE, HYDROXYCHLOROQUINE, RISEDRONATE, ATORVASTATIN CALCIUM, CEPHRADINE. Patient recovered.

Rapamune Side Effects Report #5097619-4
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on Aug 24, 2006. Male patient, 41 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, thrombocytopenia. Rapamune dosage: 1 MG 1X PER 1 DAY. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5123407-6
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on Oct 03, 2006. Male patient, 41 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, thrombocytopenia. Rapamune dosage: 1 MG 1X PER 1 DAY ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4700516-4
Rapamune side effect was reported by a Consumer or non-health professional from on June 13, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood phosphorus increased, blood sodium decreased, complications of transplanted kidney, kidney transplant rejection, renal tubular necrosis, thrombocytopenia, white blood cell count decreased. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4716729-1
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on July 04, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood phosphorus increased, blood sodium decreased, kidney transplant rejection, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4757823-9
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on Aug 24, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood sodium decreased, kidney transplant rejection, lymphocyte percentage decreased, monocyte percentage increased, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. During the same period patient was treated with NEORAL, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5055697-2
Rapamune side effect was reported by a Physician from UNITED STATES on July 07, 2006. Male patient, 30 years of age, weighting 214.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, dialysis , kidney transplant rejection, leukopenia, renal tubular necrosis, renal vein occlusion, thrombocytopenia, vascular stenosis. Rapamune dosage: 10 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with HYDRALAZINE, LABETALOL, NILSTAT, BACTRIM, NEXIUM, NIFEDIPINE, FENOLDOPAM, CLONIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5059027-1
Rapamune side effect was reported by a Physician from UNITED STATES on July 07, 2006. Male patient, 30 years of age, weighting 214.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, dialysis , kidney transplant rejection, leukopenia, renal tubular necrosis, renal vessel disorder, thrombocytopenia, vascular stenosis. Rapamune dosage: 10 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with HYDRALAZINE, LABETALOL, NILSTAT, BACTRIM, NEXIUM, NIFEDIPINE, FENOLDOPAM, CLONIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5096652-6
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on Aug 24, 2006. Male patient, 29 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cardiac failure, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, CARDEGIC, AMLODIPINE BESYLATE, VALACYCLOVIR, DEPAKENE, HEPARIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5119916-6
Rapamune side effect was reported by a Health Professional from FRANCE on Sept 18, 2006. Male patient, 29 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cardiac failure, myocardial ischaemia, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL, CARDEGIC, AMLODIPINE, VALACYCLOVIR, DEPAKINE, HEPARIN. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #5009031-4
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on May 05, 2006. Male patient, 29 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cardiac failure, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, CARDEGIC, AMLOR, VALACYCLOVIR, DEPAKENE, HEPARIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5482487-9
Rapamune side effect was reported by a Health Professional from UNITED STATES on Oct 04, 2007. Male patient, 21 years of age, was diagnosed with prophylaxis against transplant rejection, cytomegalovirus infection  and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiac failure, haemolytic uraemic syndrome, multi-organ failure, sepsis , thrombocytopenia, transplant rejection. Rapamune dosage: unknown. During the same period patient was treated with GANCICLOVIR, METHYLPREDNISOLONE. Patient died.

Rapamune Side Effects Report #5118689-0
Rapamune side effect was reported by a Consumer or non-health professional from IRAN (ISLAMIC REPUBLIC OF) on Sept 18, 2006. Male patient, 20 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, thrombocytopenia. Rapamune dosage: ORAL; 2MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE, ATENOLOL, PRAZOSIN GITS, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5177000-X
Rapamune side effect was reported by a Health Professional from IRAN (ISLAMIC REPUBLIC OF) on Nov 25, 2006. Male patient, 18 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: body temperature increased, kidney transplant rejection, thrombocytopenia. Rapamune dosage: 6 MG ONSET, ORAL. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5074411-8
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on July 28, 2006. Female patient was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: leukopenia, rectal haemorrhage, thrombocytopenia. Rapamune dosage: unknown. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #5724007-7
Rapamune side effect was reported by a Physician from FRANCE on Apr 23, 2008. Female patient was diagnosed with prophylaxis against transplant rejection, hypercholesterolaemia, hypertension and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, bronchitis , pneumonia fungal, pneumonia pneumococcal, pyrexia, thrombocytopenia. Rapamune dosage: 3 MG TOTAL DAILY. During the same period patient was treated with ELISOR, TAREG, CELLCEPT, DETENSIEL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5897829-X
Rapamune side effect was reported by a Physician from IRAN (ISLAMIC REPUBLIC OF) on Sept 04, 2008. Male patient, weighting 138.9 lb, was diagnosed with prophylaxis against transplant rejection, hypertension and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, thrombocytopenia. Rapamune dosage: unknown. During the same period patient was treated with PREDNISOLONE, PRAZOSIN, CYCLOSPORINE, ATENOLOL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4596708-8
Rapamune side effect was reported by a Consumer or non-health professional from on Feb 15, 2005. Female patient was diagnosed with graft versus host disease and was treated with Rapamune. After drug was administered, patient experienced the following side effects: disease progression, graft versus host disease, renal failure acute, thrombocytopenia. Rapamune dosage: 10 MG LOADING DOSE FOLLOWED BY DAILY DOSE OF 5 MG, ORAL ; 80% REDUCTION. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient recovered.

Rapamune Side Effects Report #4596838-0
Rapamune side effect was reported by a Consumer or non-health professional from on Feb 15, 2005. Female patient was diagnosed with graft versus host disease and was treated with Rapamune. After drug was administered, patient experienced the following side effects: graft versus host disease, herpes simplex , renal failure acute, thrombocytopenia. Rapamune dosage: 1ST TRIAL: 10 MG LOADING DOSE FOLLOWED BY DAILY DOSE OF 5MG, ORAL. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient recovered.

Rapamune Side Effects Report #4596844-6
Rapamune side effect was reported by a Consumer or non-health professional from on Feb 15, 2005. Female patient was diagnosed with graft versus host disease and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal failure acute, thrombocytopenia. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient recovered.


Rapamune Side Effects Report #4714441-6
Rapamune side effect was reported by a Health Professional from CANADA on July 04, 2005. Male patient, 61 years of age, was treated with Rapamune. After drug was administered, patient experienced the following side effects: thrombocytopenia. Rapamune dosage: unknown. Patient recovered.