Rapamune and renal tubular necrosis Patient Reports February 11, 2012

Rapamune Side Effects Report #5197412-8
Rapamune side effect was reported by a Health Professional from UNITED STATES on May 23, 2006. Male patient, 44 years of age, weighting 169.8 lb, was diagnosed with renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: hepatic enzyme increased, renal tubular necrosis. Rapamune dosage: 1 MG TABLETS, ORAL. During the same period patient was treated with CYCLOSPORINE, PREDNISONE, SIMULET, MYCOPHENOLIC ACID. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4606866-4
Rapamune side effect was reported by a Consumer or non-health professional from on Feb 25, 2005. Female patient, 40 years of age, weighting 185.2 lb, was diagnosed with renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood lactate dehydrogenase increased, cytomegalovirus infection , kidney transplant rejection, lung infiltration, renal failure acute, renal tubular necrosis, thrombotic microangiopathy. Rapamune dosage: 4 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT, PREDNISONE, ANTIHYPERTENSIVES. Patient was hospitalized and became disabled. Patient recovered.

Rapamune Side Effects Report #4735280-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on July 21, 2005. Male patient, 69 years of age, weighting 207.5 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: lymphocele, renal failure acute, renal tubular disorder, renal tubular necrosis, seroma. Rapamune dosage: 3 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with NEORAL, MYCOSTATIN, METAMUCIL, QUINIDINE SULPHATE, BACTRIM DS, NORVASC, CELLCEPT. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4818617-9
Rapamune side effect was reported by a Health Professional from SPAIN on Oct 26, 2005. Male patient, 69 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: diabetes mellitus, insomnia, kidney transplant rejection, pain , renal tubular necrosis, urinary tract infection . Rapamune dosage: 7 MG 1X PER 1 DAY. During the same period patient was treated with SIMULECT, CELLCEPT, DOXAZOSIN, SULFAMETHOXAZOLE, ZANTAC, ORALDINE, PREDNISONE, ATORVASTATIN CALCIUM. Patient recovered.


Rapamune Side Effects Report #4869643-5
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Dec 23, 2005. Male patient, 69 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cytomegalovirus antibody positive, diabetes mellitus, insomnia, kidney transplant rejection, pain , renal tubular necrosis, urinary tract infection . Rapamune dosage: 7 MG 1X PER 1 DAY ORAL. During the same period patient was treated with SIMULECT, CELLCEPT, DOXAZOSIN, SULFAMETHOXAZOLE, ZANTAC, ORALDINE, PREDNISONE. Patient recovered.

Rapamune Side Effects Report #4869661-7
Rapamune side effect was reported by a Consumer or non-health professional from BELGIUM on Dec 19, 2005. Male patient, 69 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, condition aggravated, dialysis , hypertension, pneumonia , pulmonary hypertension , pulmonary oedema, renal tubular necrosis. Rapamune dosage: 5 MG / DAY. During the same period patient was treated with ZENAPAX, ZOVIRAX, MEDROL, CELLCEPT, BACTRIM DS, AMLODIPINE BESYLATE, RYDENE, TENORMIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4688369-4
Rapamune side effect was reported by a Consumer or non-health professional from on June 02, 2005. Female patient, 68 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, dialysis , differential white blood cell count abnormal, kidney transplant rejection, renal cyst, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with ZENEPAX, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient recovered.

Rapamune Side Effects Report #4767627-9
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 26, 2005. Male patient, 66 years of age, weighting 246.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis, transplant rejection. Rapamune dosage: unknown. During the same period patient was treated with CELLCEPT, PREDNISONE, BACTRIM, PROCARDIA. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4883894-5
Rapamune side effect was reported by a Consumer or non-health professional from SWEDEN on Jan 02, 2006. Male patient, 64 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood pressure abnormal, haemodialysis, peritoneal dialysis, procedural hypotension, renal failure, renal tubular necrosis, respiratory disorder, surgical procedure repeated. Rapamune dosage: 15 MG 1X PER 1 DAY; ORAL (SEE IMAGE). Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4837029-5
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 08, 2005. Female patient, 62 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, haemodialysis, kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 2 + 3MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4929354-4
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on Feb 14, 2006. Male patient, 60 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis, thrombotic microangiopathy, tubulointerstitial nephritis. Rapamune dosage: 5 MG 1X PER 1 DAY/STARTED ON POST TRANSPLANT DAY 4. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL, SIMULECT. Patient recovered.

Rapamune Side Effects Report #4875863-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 27, 2005. Male patient, 59 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, dialysis , fluid overload, hyperkalaemia, oliguria, renal tubular necrosis, thrombocytopenia. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ZENAPAX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4585552-3
Rapamune side effect was reported by a Consumer or non-health professional from on Jan 31, 2005. Male patient, 58 years of age, weighting 282.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anuria, blood creatine increased, haemodialysis, hydronephrosis, obstructive uropathy, renal lymphocele, renal tubular necrosis, thrombotic microangiopathy. Rapamune dosage: unknown. During the same period patient was treated with NEORAL, PREDNISONE, OMEPRAZOLE, NORVASC, VALCYTE, BACTRIM, BUMEX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4855550-0
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Dec 01, 2005. Male patient, 58 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, renal tubular necrosis. Rapamune dosage: 8 MG DOSE; ORAL. During the same period patient was treated with DOXAZOSIN MESYLATE, AMLODIPINE, CLORAZEPATE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4869562-4
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Dec 23, 2005. Male patient, 58 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: arterial stenosis, haemodialysis, kidney transplant rejection, renal impairment, renal tubular necrosis, vascular graft complication. Rapamune dosage: 8 MG 1X PER 1 DAY ORAL; SEE IMAGE. During the same period patient was treated with DOXAZOSIN MESYLATE, AMLODIPINE, CLORAZEPATE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4869613-7
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Dec 14, 2005. Male patient, 58 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, kidney transplant rejection, renal impairment, renal infarct, renal tubular necrosis, vascular graft complication. Rapamune dosage: 8 MG 1 PER 1 DAY; 6MG 1X PER 1 DAY. During the same period patient was treated with DOXAZOSIN MESYLATE, AMLODIPINE, CLORAZEPATE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4881936-4
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Jan 03, 2006. Male patient, 57 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: diarrhoea, haemodialysis, procedural hypotension, renal tubular necrosis. Rapamune dosage: 5 MG, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, SULFAMETHOXAZOLE, GANCICLOVIR, PROTONIX, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4889446-5
Rapamune side effect was reported by a Physician from SPAIN on Jan 12, 2006. Male patient, 57 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, leukopenia, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, SULFAMETHOXAZOLE, GANCICLOVIR. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4960394-5
Rapamune side effect was reported by a Physician from SPAIN on Mar 17, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, gastrointestinal haemorrhage, nephrolithiasis, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4975598-5
Rapamune side effect was reported by a Health Professional from SPAIN on Apr 03, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, complications of transplanted kidney, gastrointestinal disorder, gastrointestinal haemorrhage, ill-defined disorder, nephrocalcinosis, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4978339-0
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Apr 06, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, complications of transplanted kidney, gastrointestinal haemorrhage, nephrocalcinosis, renal tubular necrosis, small intestinal haemorrhage, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4998578-2
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Apr 24, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, gastrointestinal haemorrhage, haemodialysis, nephrocalcinosis, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5038742-X
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on June 15, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: bone marrow toxicity, complications of transplanted kidney, gastrointestinal haemorrhage, haematocrit decreased, kidney transplant rejection, nephrocalcinosis, renal tubular necrosis, small intestinal haemorrhage, thrombocytopenia. Rapamune dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5046908-8
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on June 27, 2006. Female patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: abscess , bone marrow toxicity, gastrointestinal haemorrhage, haemodialysis, nephrocalcinosis, procedural site reaction, renal tubular necrosis, thrombocytopenia, transplant rejection. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with GANCICLOVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4776304-X
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Sept 08, 2005. Male patient, 55 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatinine increased, complications of transplanted kidney, haemodialysis, renal tubular necrosis. Rapamune dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with RANITIDINE, FUROSEMIDE, SULFAMETHOXAZOLE, FLUOXETINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4725780-7
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on July 13, 2005. Female patient, 54 years of age, weighting 124.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: aortic atherosclerosis, blood creatinine increased, nausea , post procedural complication, post procedural haematoma, renal artery stenosis, renal tubular necrosis, suture related complication, ureteric obstruction. Rapamune dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, CLONIDINE, AMLODIPINE BESYLATE, LABETALOL HYDROCHLORIDE, VALGANCICLOVIR, GATIFLOXACIN, BUPRENORPHINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4790497-X
Rapamune side effect was reported by a Physician from UNITED STATES on Sept 23, 2005. Female patient, 54 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: aortic arteriosclerosis, arterial stenosis, post procedural complication, post procedural haematoma, renal tubular necrosis, ureteric obstruction. Rapamune dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with PREDNISONE, CLONIDINE, AMLODIPINE BESYLATE, LABETALOL HYDROCHLORIDE, VALGANCICLOVIR, GATIFLOXACIN, BUPRENORPHINE, ONDANSETRON. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5059975-2
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on July 07, 2006. Male patient, 52 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, haemodialysis, renal tubular necrosis, seroma, urinary fistula, urinary tract infection enterococcal, urinary tract infection staphylococcal. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5080804-5
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on July 27, 2006. Male patient, 52 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, kidney transplant rejection, renal tubular necrosis, seroma, urinary fistula, urinary tract infection enterococcal, urinary tract infection staphylococcal. Rapamune dosage: unknown. During the same period patient was treated with CELLCEPT, SIMULECT. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #5008992-7
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on May 10, 2006. Male patient, 52 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 4 MG 1X PER 1 DAY ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5024823-3
Rapamune side effect was reported by a Health Professional from SPAIN on May 25, 2006. Male patient, 52 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, renal tubular necrosis, urinary fistula. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4775088-9
Rapamune side effect was reported by a Consumer or non-health professional from SPAIN on Sept 13, 2005. Male patient, 51 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: impaired healing, postoperative infection, renal impairment, renal tubular necrosis, vesical fistula. Rapamune dosage: 6 MG 1X PER 1 DAY. During the same period patient was treated with ZENAPAX, PREDNISONE, PROGRAF, FUROSEMIDE, INSULIN, ARANESP, SEPTRA. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4743006-5
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on July 29, 2005. Female patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haematocrit decreased, haemoglobin decreased, hydronephrosis, kidney transplant rejection, lymphocele, nephrostomy tube placement, perinephric collection, renal tubular necrosis, white blood cell count decreased. Rapamune dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with ALLOPURINOL, AMBIEN, ATENOLOL, COUMADIN, NPH INSULIN, IMODIUM, LEVAQUIN, HYDROCODONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4825227-6
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Oct 31, 2005. Male patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, graft dysfunction, kidney transplant rejection, renal tubular necrosis, tubulointerstitial nephritis. Rapamune dosage: 3 MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE, SULFAMETHOXAZOLE, RANITIDINE, PREDNISONE, SIMVASTATIN. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4830608-0
Rapamune side effect was reported by a Health Professional from BRAZIL on Nov 04, 2005. Male patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, renal tubular necrosis, tubulointerstitial nephritis, urinary tract infection enterococcal, urinary tract obstruction. Rapamune dosage: 3 MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE, SULFAMETHOXAZOLE, RANITIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4836543-6
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 07, 2005. Female patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4848107-9
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 23, 2005. Female patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISONE, SULFAMETHAXAZOLE W. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4851329-4
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 24, 2005. Male patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, renal tubular necrosis, tubulointerstitial nephritis, urinary tract infection enterococcal, urinary tract obstruction. Rapamune dosage: 3 MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE, SULFAMETHOXAZOLE, RANITIDINE, PREDNISONE, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5106897-4
Rapamune side effect was reported by a Health Professional from IRAN (ISLAMIC REPUBLIC OF) on Sept 03, 2006. Female patient, 48 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, oedema peripheral, renal tubular necrosis. Rapamune dosage: 6 MG INITIALLY; 1 MG 1X PER 1 DAY; 2 MG 1X PER 1 DAY. During the same period patient was treated with SANDIMMUNE, PREDNISONE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4636852-X
Rapamune side effect was reported by a Consumer or non-health professional from on Apr 01, 2005. Male patient, 46 years of age, weighting 218.3 lb, was diagnosed with prophylaxis against transplant rejection, kidney transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: hyperglycaemia, kidney transplant rejection, renal tubular necrosis, white blood cell count decreased. Rapamune dosage: 6 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with PREDNISONE, CELLCEPT, LOPRESSOR, LIPITOR, BACTRIM DS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4889670-1
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 13, 2006. Male patient, 46 years of age, weighting 219.4 lb, was diagnosed with prophylaxis against transplant rejection, kidney transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: hyperglycaemia, kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 6 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with PREDNISONE, CELLCEPT, LOPRESSOR, LIPITOR, BACTRIM DS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5076378-5
Rapamune side effect was reported by a Health Professional from GREECE on Aug 03, 2006. Female patient, 41 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: graft thrombosis, kidney transplant rejection, leg amputation, peripheral ischaemia, renal tubular necrosis, sepsis . Rapamune dosage: 10 MG 1X PER 1 DAY; 4 MG 1X PER 1 DAY ; 5 MG 1X PER 1 DAY. During the same period patient was treated with MYCOPHENOLATE MOFETIL, OMEPRAZOLE, AMIKACIN, CEFTAZIDIME, CLONAZEPAM. Patient was hospitalized and became disabled. Patient recovered.

Rapamune Side Effects Report #5144511-2
Rapamune side effect was reported by a Health Professional from GREECE on Oct 30, 2006. Female patient, 41 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, graft thrombosis, kidney transplant rejection, leg amputation, nephrectomy, peripheral ischaemia, renal tubular necrosis, sepsis . Rapamune dosage: 10 MG 1X PER 1 DAY ORAL; 4 MG 1X PER 1 DAY ORAL; 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, OMEPRAZOLE, AMIKACIN, CEFTAZIDIME, CLONAZEPAM. Patient was hospitalized and became disabled. Patient died.

Rapamune Side Effects Report #4732421-1
Rapamune side effect was reported by a Physician from UNITED STATES on July 25, 2005. Female patient, 41 years of age, weighting 180.6 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: nausea , oral intake reduced, perirenal haematoma, peritoneal dialysis, renal tubular necrosis. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with PROGRAF, MYCELEX, VALCYTE, TUMS, LASIX, PREDNISONE, ZANAC, SEPTRA. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4921069-1
Rapamune side effect was reported by a Consumer or non-health professional from ARGENTINA on Feb 10, 2006. Female patient, 41 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, complications of transplanted kidney, haemodialysis, hydronephrosis, obstructive uropathy, renal tubular necrosis. Rapamune dosage: 12 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with CELLCEPT. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4929355-6
Rapamune side effect was reported by a Consumer or non-health professional from ARGENTINA on Feb 10, 2006. Female patient, 41 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anuria, complications of transplanted kidney, haemodialysis, hydronephrosis, obstructive uropathy, renal tubular necrosis. Rapamune dosage: 12 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT. Patient was hospitalized and became disabled. Patient recovered.

Rapamune Side Effects Report #4847497-0
Rapamune side effect was reported by a Health Professional from BRAZIL on Nov 23, 2005. Male patient, 40 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, renal tubular necrosis. Rapamune dosage: 2 MG 1X PER 1 DAY; 3 MG 1X PER 1 DAY. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4700516-4
Rapamune side effect was reported by a Consumer or non-health professional from on June 13, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood phosphorus increased, blood sodium decreased, complications of transplanted kidney, kidney transplant rejection, renal tubular necrosis, thrombocytopenia, white blood cell count decreased. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4716729-1
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on July 04, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood phosphorus increased, blood sodium decreased, kidney transplant rejection, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4733100-7
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on July 20, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood phosphorus increased, kidney transplant rejection, lymphocyte percentage decreased, neutrophil percentage increased, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. During the same period patient was treated with NEORAL, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4757823-9
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on Aug 24, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, blood chloride decreased, blood sodium decreased, kidney transplant rejection, lymphocyte percentage decreased, monocyte percentage increased, renal tubular necrosis, thrombocytopenia. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. During the same period patient was treated with NEORAL, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4837055-6
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 07, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 2 MG 1X PER 1 DAY. During the same period patient was treated with SULFAMETHOXAZOLE, CYCLOSPORINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4848112-2
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 23, 2005. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, renal tubular necrosis. Rapamune dosage: 2 MG 1X PER 1 DAY. During the same period patient was treated with CYCLOSPORINE, PREDNISONE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4686730-5
Rapamune side effect was reported by a Consumer or non-health professional from on May 31, 2005. Female patient, 36 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: unknown. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4713007-1
Rapamune side effect was reported by a Consumer or non-health professional from ITALY on July 06, 2005. Female patient, 36 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anuria, complications of transplanted kidney, renal tubular necrosis, urinoma. Rapamune dosage: unknown. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4837005-2
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 07, 2005. Male patient, 35 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 3 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CYCLOSPORINE, PREDNISONE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4847011-X
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 23, 2005. Male patient, 35 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 3 MG 1X PER 1 DAY. During the same period patient was treated with CYCLOSPORINE, PREDNISONE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5009139-3
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on May 08, 2006. Male patient, 35 years of age, weighting 207.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cardiac failure congestive, condition aggravated, hyperglycaemia, kidney transplant rejection, nephritis, pneumonia primary atypical, renal tubular necrosis, ultrasound kidney abnormal. Rapamune dosage: 3 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT, MEDROL ACETATE, BACTRIM, VALCYTE, PROTONIX, LOPRESSOR, NORVASC, AVANDIA. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4664839-X
Rapamune side effect was reported by a Consumer or non-health professional from on May 04, 2005. Male patient, 34 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, ischaemia, lymphocele, renal tubular necrosis. Rapamune dosage: 6 MG ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ZENAPAX. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #4679017-8
Rapamune side effect was reported by a Consumer or non-health professional from on May 19, 2005. Male patient, 34 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, ischaemia, lymphocele, post procedural complication, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ZENAPAX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5055697-2
Rapamune side effect was reported by a Physician from UNITED STATES on July 07, 2006. Male patient, 30 years of age, weighting 214.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, dialysis , kidney transplant rejection, leukopenia, renal tubular necrosis, renal vein occlusion, thrombocytopenia, vascular stenosis. Rapamune dosage: 10 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with HYDRALAZINE, LABETALOL, NILSTAT, BACTRIM, NEXIUM, NIFEDIPINE, FENOLDOPAM, CLONIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5059027-1
Rapamune side effect was reported by a Physician from UNITED STATES on July 07, 2006. Male patient, 30 years of age, weighting 214.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: anaemia, dialysis , kidney transplant rejection, leukopenia, renal tubular necrosis, renal vessel disorder, thrombocytopenia, vascular stenosis. Rapamune dosage: 10 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with HYDRALAZINE, LABETALOL, NILSTAT, BACTRIM, NEXIUM, NIFEDIPINE, FENOLDOPAM, CLONIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4708497-4
Rapamune side effect was reported by a Physician from CANADA on June 22, 2005. Male patient, 30 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: 7 MG 1X PER 1 DAY ORAL. During the same period patient was treated with PREDNISONE, PROGRAF, ZENAPAX, NORVASC, METOPROLOL TARTRATE, FERROUS GLUCONATE, SEPTRA. Patient recovered.

Rapamune Side Effects Report #4927922-7
Rapamune side effect was reported by a Consumer or non-health professional from CANADA on Feb 14, 2006. Male patient, 30 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal injury, renal tubular necrosis. Rapamune dosage: 7 MG 1X PER 1 DAY ORAL. During the same period patient was treated with PREDNISONE, PROGRAF, ZENAPAX, NORVASC, METOPROLOL, FERROUS GLUCONATE, SEPTRA. Patient recovered.

Rapamune Side Effects Report #5032222-3
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on June 06, 2006. Male patient, 30 years of age, weighting 214.2 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: atelectasis, blood pressure increased, kidney transplant rejection, pneumonia , renal tubular necrosis, renal vessel disorder, venous stenosis. Rapamune dosage: 10 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with HYDRALAZINE, LABETALOL, NILSTAT, BACTRIM, NEXIUM, NIFEDIPINE, FENOLDOPAM, CLONIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5055178-6
Rapamune side effect was reported by a Health Professional from CHILE on July 03, 2006. Female patient, 26 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, lung disorder, pyrexia, renal tubular necrosis, sputum purulent. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, NIFEDIPINE, FUROSEMIDE, HYDRAZIDE, METHYLDOPA, DOXAZOSIN, CLONIDINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5096642-3
Rapamune side effect was reported by a Consumer or non-health professional from CHILE on Aug 24, 2006. Female patient, 26 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, lung disorder, pyrexia, renal tubular necrosis, sputum purulent. Rapamune dosage: 10 MG 1X PER 1 DAY ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, NIFEDIPINE, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5029187-7
Rapamune side effect was reported by a Health Professional from CHILE on June 02, 2006. Female patient, 26 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: haemodialysis, lung disorder, pyrexia, renal surgery, renal tubular necrosis, sputum purulent. Rapamune dosage: 10 MG 1X PER 1 DAY; ORAL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5081987-3
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Aug 03, 2006. Male patient, 25 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, renal impairment, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #5084002-0
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Aug 03, 2006. Male patient, 25 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, dialysis , haematocrit increased, haemoglobin increased, kidney transplant rejection, renal impairment, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4836435-2
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 07, 2005. Male patient, 25 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatinine increased, dialysis , kidney transplant rejection, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4699831-2
Rapamune side effect was reported by a Consumer or non-health professional from on June 10, 2005. Male patient, 24 years of age, weighting 240.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: back pain , complications of transplanted kidney, dyspnoea, haematocrit decreased, haemodialysis, hypertension, pyrexia, renal tubular necrosis, urinary tract infection . Rapamune dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with ZENAPAX, PREDNISONE, CELLCEPT, FENTANYL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4977103-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 04, 2006. Male patient, 24 years of age, weighting 195.1 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: dialysis , fluid overload, hypertension, renal tubular necrosis. Rapamune dosage: 10 MG 1X PER 1 DAY, ORAL : 12 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5234615-8
Rapamune side effect was reported by a Physician from IRAN (ISLAMIC REPUBLIC OF) on Feb 03, 2007. Male patient, weighting 108.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5277151-5
Rapamune side effect was reported by a Physician from BRAZIL on Mar 19, 2007. Male patient, weighting 155.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with PREDNISONE, SULFAMETHOXAZOLE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5280535-2
Rapamune side effect was reported by a Physician from BRAZIL on Mar 19, 2007. Male patient, weighting 157.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with PREDNISONE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5317423-9
Rapamune side effect was reported by a Physician from NETHERLANDS on Apr 30, 2007. Female patient, weighting 129.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 15 MG. During the same period patient was treated with PREDNISOLONE, DACLIZUMAB, MYCOPHENOLATE MOFETIL. Patient recovered.

Rapamune Side Effects Report #5391535-6
Rapamune side effect was reported by a Physician from FRANCE on Mar 09, 2007. Male patient, weighting 145.5 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: cachexia, cytomegalovirus infection , dehydration, diarrhoea, graft dysfunction, renal tubular necrosis, urinary tract disorder. Rapamune dosage: unknown. During the same period patient was treated with DIURETICS, THYMOGLOBULIN, CELLCEPT. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5886940-5
Rapamune side effect was reported by a Physician from IRAN (ISLAMIC REPUBLIC OF) on Sept 03, 2008. Female patient, weighting 130.1 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: oedema, renal tubular necrosis, transplant rejection. Rapamune dosage: 6 MG INITIALLY. During the same period patient was treated with PREDNISONE, SANDIMMUNE. Patient was hospitalized. Patient recovered.


Rapamune Side Effects Report #5176350-0
Rapamune side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 30, 2006. Male patient, 50 years of age, was diagnosed with pancreas transplant , renal transplant, anaemia and was treated with Rapamune. After drug was administered, patient experienced the following side effects: nephritis interstitial, renal impairment, renal tubular necrosis. Rapamune dosage: unknown. During the same period patient was treated with RECORMON, ALFACALCIDOL, ATENOLOL, BICARBONATE IN PLASTIC CONTAINER. Patient recovered.

Rapamune Side Effects Report #4663142-1
Rapamune side effect was reported by a Consumer or non-health professional from on May 02, 2005. Male patient, child 8 years of age, weighting 63.05 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatine increased, complications of transplanted kidney, renal artery occlusion, renal tubular necrosis, renal vein occlusion. Rapamune dosage: 3 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with MAGNESIUM GLUCONATE, PREDNISONE, ZANTAC, BACTRIM, PROGRAF, LABETALOL, NORVASC. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5086055-2
Rapamune side effect was reported by a Consumer or non-health professional from GERMANY on Aug 08, 2006. Female patient, 63 years of age, was treated with Rapamune. After drug was administered, patient experienced the following side effects: arteriopathic disease, ascites, hypovolaemia, oedema peripheral, pleural effusion, renal artery stenosis, renal tubular necrosis, renal vessel disorder. Rapamune dosage: unknown. During the same period patient was treated with TACROLIMUS, PREDNISOLONE. Patient recovered.

Rapamune Side Effects Report #4570737-2
Rapamune side effect was reported by a Consumer or non-health professional from on Jan 20, 2005. Female patient, 60 years of age, was treated with Rapamune. After drug was administered, patient experienced the following side effects: glomerulonephritis proliferative, nephrotic syndrome, renal tubular necrosis. Rapamune dosage: unknown. Patient recovered.

Rapamune Side Effects Report #4785068-5
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Sept 19, 2005. Male patient, 55 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatinine increased, complications of transplanted kidney, haemodialysis, renal tubular necrosis, urine output increased. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with RANITIDINE, FUROSEMIDE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4791152-2
Rapamune side effect was reported by a Health Professional from BRAZIL on Sept 22, 2005. Male patient, 55 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood creatinine increased, complications of transplanted kidney, haemodialysis, renal tubular necrosis. Rapamune dosage: 6 MG 1X PER 1 DAY ORAL. During the same period patient was treated with RANITIDINE, FUROSEMIDE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4801220-4
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Oct 06, 2005. Male patient, 55 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, haemodialysis, polyuria, renal tubular necrosis. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with RANITIDINE, FUROSEMIDE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4726042-4
Rapamune side effect was reported by a Health Professional from UNITED KINGDOM on July 20, 2005. Male patient, 54 years of age, was treated with Rapamune. After drug was administered, patient experienced the following side effects: renal tubular necrosis. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. During the same period patient was treated with ALFACALCIDOL, CANDESARTAN, ASPIRIN, CELLCEPT. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4837026-X
Rapamune side effect was reported by a Consumer or non-health professional from BRAZIL on Nov 07, 2005. Male patient, 40 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, haemodialysis, kidney transplant rejection, renal tubular necrosis. Rapamune dosage: 2 + 3MG 1X PER 1 DAY ORAL. During the same period patient was treated with CYCLOSPORINE, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5597167-9
Rapamune side effect was reported by a Physician from UNITED STATES on Jan 07, 2008. Female patient was treated with Rapamune. After drug was administered, patient experienced the following side effects: nephritis interstitial, renal tubular necrosis. Rapamune dosage: 10 MG/DAY BEGINNING ON DAY 4 POST-TRANSPLANT. During the same period patient was treated with ZENAPAX, CELLCEPT. Patient recovered.