Rapamune and blood alkaline phosphatase increased Patient Reports February 11, 2012

Rapamune Side Effects Report #4912983-1
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 31, 2006. Female patient, 74 years of age, was diagnosed with prophylaxis against transplant rejection, bronchopulmonary aspergillosis, mucormycosis, tuberculin test positive and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood creatinine increased, computerised tomogram abnormal, decreased immune responsiveness, pulmonary mycosis. Rapamune dosage: unknown. During the same period patient was treated with CANCIDAS, FLUCONAZOLE, ISONIAZID, PREDNISONE, TACROLIMUS, VORICONAZOLE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4908971-1
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 26, 2006. Male patient, 68 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, atelectasis, biliary tract disorder, blood alkaline phosphatase increased, blood glucose increased, blood pressure diastolic decreased, blood sodium decreased, body temperature. Rapamune dosage: 1 MG 1X PER 1 DAY, ORAL; 2MG 1X PER 1 DAY, ORAL. During the same period patient was treated with CELLCEPT, PREDNISONE, ZENAPAX, LOPRESSOR, LASIX, CLONIDINE, NORVASC. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4573791-7
Rapamune side effect was reported by a Consumer or non-health professional from on Jan 21, 2005. Male patient, 67 years of age, weighting 289.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, biliary anastomosis complication, biliary dilatation, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, blood urea increased, fatigue, insomnia. Rapamune dosage: 6 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with ASPIRIN, PRAVACHOL, LEVAQUIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4643364-6
Rapamune side effect was reported by a Consumer or non-health professional from on Apr 08, 2005. Male patient, 67 years of age, weighting 289.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, biliary anastomosis complication, biliary dilatation, biliary tract disorder, bladder cancer

, blood alkaline phosphatase increased, blood cholesterol increased, blood creatinine increased. Rapamune dosage: 6 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with ASPIRIN, PRAVACHOL, LEVAQUIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4672903-4
Rapamune side effect was reported by a Health Professional from on May 09, 2005. Male patient, 67 years of age, weighting 289.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, biliary anastomosis complication, biliary dilatation, bladder cancer

, bladder neoplasm, blood alkaline phosphatase increased, blood creatinine increased, blood glucose increased. Rapamune dosage: 6 MG 1X PER 1 DAY ORAL. During the same period patient was treated with ASPIRIN, PRAVACHOL, LEVAQUIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4685759-0
Rapamune side effect was reported by a Consumer or non-health professional from on June 01, 2005. Male patient, 67 years of age, weighting 289.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, biliary anastomosis complication, biliary dilatation, bladder cancer

, blood alkaline phosphatase increased, blood creatinine increased, blood lactate dehydrogenase increased, blood urea increased. Rapamune dosage: 6 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with ASPIRIN, PRAVACHOL, LEVAQUIN. Patient was hospitalized. Patient died on 05/31/2005.

Rapamune Side Effects Report #4687983-X
Rapamune side effect was reported by a Consumer or non-health professional from on June 01, 2005. Male patient, 67 years of age, weighting 289.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, biliary anastomosis complication, bladder cancer

, blood alkaline phosphatase increased, blood glucose increased, blood lactate dehydrogenase increased, blood pressure systolic increased, blood triglycerides increased. Rapamune dosage: 6 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with ASPIRIN, PRAVACHOL, LEVAQUIN. Patient was hospitalized. Patient died on 05/31/2005.

Rapamune Side Effects Report #5023779-7
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on May 23, 2006. Male patient, 65 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood alkaline phosphatase increased, condition aggravated, gastrointestinal haemorrhage, glomerulonephritis proliferative, haemodialysis, haemoglobin decreased, henoch-schonlein purpura, platelet count decreased. Rapamune dosage: 1 MG 1X PER 1 DAY,. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4816214-2
Rapamune side effect was reported by a Consumer or non-health professional from GERMANY on Oct 18, 2005. Female patient, 64 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood creatinine increased, candiduria, gamma-glutamyltransferase increased, vaginal candidiasis. Rapamune dosage: 4 MG ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISOLONE, ZENAPAX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4819844-7
Rapamune side effect was reported by a Consumer or non-health professional from GERMANY on Oct 26, 2005. Female patient, 64 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood creatinine increased, candiduria, gamma-glutamyltransferase increased, vaginal candidiasis. Rapamune dosage: 4 MG ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISOLONE, ZENAPAX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5009140-X
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on May 09, 2006. Female patient, 64 years of age, weighting 176.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, liver transplant rejection. Rapamune dosage: 5 MG EVERY OTHER DAY ALTERNATING WITH 6 MG EVERY OTHER DAY, ORAL. During the same period patient was treated with BACTRIM DS, VITAMINS, CALTRATE 600. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5024030-4
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on May 26, 2006. Female patient, 64 years of age, weighting 176.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood triglycerides increased, liver transplant rejection. Rapamune dosage: 5 MG EVERY OTHER DAY ALTERNATING WITH 6 MG; EVERY OTHER DAY, ORAL. During the same period patient was treated with BACTRIM DS, VITAMINS, CALTRATE 600. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5030402-4
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on June 08, 2006. Male patient, 61 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: ascites, blood alkaline phosphatase increased, blood creatinine increased, cholangitis, cholestasis, condition aggravated, cytolytic hepatitis, cytomegalovirus infection

. Rapamune dosage: unknown. During the same period patient was treated with CELLCEPT, CORTICOSTEROIDS, OMEPRAZOLE, VALACYCLOVIR, BACTRIM, MOTILIUM. Patient was hospitalized and became disabled. Patient recovered.

Rapamune Side Effects Report #5162136-X
Rapamune side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 14, 2006. Male patient, 59 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anastomotic stenosis, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, clostridial infection, dilatation intrahepatic duct acquired, gamma-glutamyltransferase increased, hepatic artery occlusion. Rapamune dosage: 2 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with ACYCLOVIR, BACTRIM DS, NEXIUM, AMARYL, TACROLIMUS, CELLCEPT. Patient recovered.

Rapamune Side Effects Report #5194170-8
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 14, 2006. Male patient, 59 years of age, was diagnosed with prophylaxis against transplant rejection, liver abscess and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anastomotic stenosis, aspartate aminotransferase increased, bile duct necrosis, blood alkaline phosphatase increased, blood bilirubin increased, cholangitis, clostridium difficile colitis, dilatation intrahepatic duct acquired. Rapamune dosage: unknown. During the same period patient was treated with CELLCEPT, ZOSYN, ACYCLOVIR, BACTRIM DS, NEXIUM, AMARYL, TACROLIMUS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5159293-8
Rapamune side effect was reported by a Consumer or non-health professional from FRANCE on Sept 30, 2005. Female patient, 58 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, cholestasis, condition aggravated, disease progression, gamma-glutamyltransferase increased, mobility decreased, oedema peripheral, osteonecrosis

, systemic inflammatory response syndrome. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, ZENAPAX, PREDNISONE, NEORAL, OMEPRAZOLE, OROCAL, NEORECORMON, VENOFER. Patient recovered.

Rapamune Side Effects Report #5032172-2
Rapamune side effect was reported by a Consumer or non-health professional from GERMANY on June 12, 2006. Male patient, 56 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, body temperature increased, gamma-glutamyltransferase increased, hepatic artery stenosis, inflammation, jaundice

, liver function test abnormal, pleural effusion. Rapamune dosage: 2 MG 1X PER 1 DAY ORAL. During the same period patient was treated with TORSEMIDE, URSODIOL, ESOMEPRAZOLE, CIPROFLOXACIN, PRIMAXIN, ALLOPURINOL, ENOXAPARIN, NEORECORMON. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5047661-4
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on June 30, 2006. Female patient, 55 years of age, weighting 179.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, dehydration, diverticulum, gastritis erosive, gastroenteritis

, haemorrhoids. Rapamune dosage: unknown. During the same period patient was treated with CELLCEPT, PREDNISONE, AMLODIPINE BESYLATE, TENORMIN, LASIX, PREVACID. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4977017-1
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 05, 2006. Female patient, 55 years of age, weighting 179.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, nausea

, transplant rejection, viral infection

. Rapamune dosage: 2 MG/1 MG EVERY OTHER DAY,. During the same period patient was treated with CELLCEPT, PREDNISONE, AMLODIPINE BESYLATE, TENORMIN, LASIX. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5140334-9
Rapamune side effect was reported by a Physician from UNITED STATES on Oct 17, 2006. Male patient, 54 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, calcinosis, cough, granuloma, haematocrit decreased, lung neoplasm, platelet count decreased. Rapamune dosage: 3 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with LASIX, CALCIUM CARBONATE, LOTENSIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5198062-X
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 21, 2006. Male patient, 54 years of age, weighting 202.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood creatine increased, calcinosis, cough, glomerular filtration rate decreased, granuloma, haematocrit decreased, haemoglobin decreased, lymphadenopathy. Rapamune dosage: 3 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with LASIX, CALCIUM CARBONATE, LOTENSIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4848586-7
Rapamune side effect was reported by a Consumer or non-health professional from ARGENTINA on Nov 23, 2005. Female patient, 54 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, dysuria, hepatic enzyme increased, liver transplant rejection, pyrexia. Rapamune dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with MEPREDNISONE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5216580-2
Rapamune side effect was reported by a Physician from FRANCE on Jan 09, 2007. Female patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase decreased, arthritis

, blood alkaline phosphatase increased, blood bicarbonate decreased, body temperature increased, creatinine renal clearance decreased, gamma-glutamyltransferase increased, haemoglobin decreased. Rapamune dosage: 5 MG 1X PER 1 DAY. During the same period patient was treated with LESCOL, CELLCEPT, PROGRAF, PAROXETINE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5125596-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 28, 2006. Female patient, 50 years of age, weighting 134.5 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: abdominal pain

, aortic arteriosclerosis, blood alkaline phosphatase increased, cholelithiasis, haemodynamic instability, hepatic steatosis, hernia

, hypovolaemia, lipase increased. Rapamune dosage: unknown. During the same period patient was treated with DELTASONE, TACROLIMUS, ZENAPAX, DILAUDID, CELEXA. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4903394-3
Rapamune side effect was reported by a Consumer or non-health professional from HONG KONG on Jan 23, 2006. Male patient, 50 years of age, was diagnosed with prophylaxis against transplant rejection, tuberculosis

and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood potassium decreased, gamma-glutamyltransferase increased, liver function test abnormal, rash

, transplant rejection. Rapamune dosage: 6 MG 1X PER 1 DAY ORAL. During the same period patient was treated with LAMIVUDINE, ADALAT. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4685063-0
Rapamune side effect was reported by a Consumer or non-health professional from on May 23, 2005. Male patient, 48 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood phosphorus decreased, chest pain

, dyspnoea exertional, musculoskeletal discomfort. Rapamune dosage: 6 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with TACROLIMUS, ZENAPAX, PREDNISONE, ATORVASTATIN CALCIUM, LOSEC, RAMIPRIL. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4700578-4
Rapamune side effect was reported by a Consumer or non-health professional from on June 14, 2005. Male patient, 48 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, angina unstable, blood alkaline phosphatase increased, blood calcium decreased, blood creatinine abnormal, blood phosphorus decreased, haemoglobin decreased. Rapamune dosage: 6 MG 1X PER 1 DAY ORAL. During the same period patient was treated with TACROLIMUS, ZENAPAX, PREDNISONE, ATORVASTATIN CALCIUM, LOSEC, RAMIPRIL, BACTRIM DS, NYSTATIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5074393-9
Rapamune side effect was reported by a Consumer or non-health professional from TURKEY on July 24, 2006. Male patient, 47 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood cholesterol increased, blood glucose increased, blood lactate dehydrogenase increased, complications of transplanted kidney. Rapamune dosage: 5 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with PENTOXIFYLLINE, NADROPARIN CALCIUM, CELLCEPT, OMEPRAZOLE, NYSTATIN, BACTRIM, MENTOPIN ACETYLCYSTEIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4948129-3
Rapamune side effect was reported by a Consumer or non-health professional from TURKEY on Feb 28, 2006. Male patient, 47 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood cholesterol increased, blood creatinine increased, blood glucose increased, blood lactate dehydrogenase increased, blood triglycerides increased, blood uric acid increased, complications of transplanted kidney. Rapamune dosage: 5 MG 1X PER 1 DAY ORAL. During the same period patient was treated with PENTOXIFYLLINE, FRAXIPARINE, CELLCEPT. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5056355-0
Rapamune side effect was reported by a Consumer or non-health professional from SINGAPORE on July 11, 2006. Male patient, 44 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, atelectasis, blood alkaline phosphatase increased, cholecystitis, eosinophilia, hypoxia. Rapamune dosage: 2 MG 2X PER 1 DAY. During the same period patient was treated with CELLCEPT, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5211437-5
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 10, 2007. Male patient, 39 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, blood alkaline phosphatase increased, blood bilirubin increased, blood calcium decreased, cholangitis, clostridium difficile colitis. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5093670-9
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2006. Male patient, 39 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bile duct obstruction, blood alkaline phosphatase increased, blood bilirubin increased, blood potassium increased, cough, dyspnoea, liver transplant rejection. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, TACROLIMUS, PEPCID, BACTRIM DS. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5145655-1
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 27, 2006. Male patient, 39 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, biliary tract disorder, blood alkaline phosphatase increased, cholangitis, clostridium difficile colitis, liver transplant rejection, thrombosis. Rapamune dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4900049-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 20, 2006. Male patient, 39 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood glucose increased, clostridium colitis, condition aggravated, diarrhoea, haematocrit decreased. Rapamune dosage: unknown. During the same period patient was treated with IMMUNOSUPPRESSIVE AGENTS, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE, ACYCLOVIR. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4704554-7
Rapamune side effect was reported by a Consumer or non-health professional from on June 16, 2005. Female patient, 34 years of age, weighting 119.5 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Rapamune. After drug was administered, patient experienced the following side effects: asthenia, blood alkaline phosphatase increased, blood potassium decreased, cytomegalovirus viraemia, dialysis

, diarrhoea, haematocrit decreased, haemoglobin decreased, immunosuppression. Rapamune dosage: unknown. During the same period patient was treated with PREDNISONE, PROGRAF. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5245366-8
Rapamune side effect was reported by a Physician from GERMANY on Feb 19, 2007. Male patient, weighting 158.7 lb, was diagnosed with prophylaxis against transplant rejection, hepatic neoplasm malignant recurrent, blood bilirubin increased, prophylaxis against gastrointestinal ulcer, cholangitis, inflammation and was treated with Rapamune. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, biliary anastomosis complication, blood alkaline phosphatase increased, blood bilirubin increased, bronchopneumonia, c-reactive protein increased, cholangitis, cholestasis, cytomegalovirus infection

. Rapamune dosage: unknown. During the same period patient was treated with URSODIOL, NEXIUM, CELLCEPT, PRIMAXIN. Patient was hospitalized. Patient died on 11/13/2006.

Rapamune Side Effects Report #5297390-7
Rapamune side effect was reported by a Physician from GERMANY on Apr 05, 2007. Male patient, weighting 158.7 lb, was diagnosed with prophylaxis against transplant rejection, hepatic neoplasm malignant recurrent, blood bilirubin increased, prophylaxis against gastrointestinal ulcer, cholangitis, inflammation, hyperuricaemia and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bilirubin increased, c-reactive protein increased, hepatic artery stenosis, pleural effusion, pneumonia

, transplant failure. Rapamune dosage: unknown. During the same period patient was treated with URSODIOL, NEXIUM, CIPROFLOXACIN, TACROLIMUS, ALLOPURINOL. Patient was hospitalized. Patient died on 11/13/2006.

Rapamune Side Effects Report #5140695-0
Rapamune side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 20, 2006. Female patient, 52 years of age, was diagnosed with immunosuppression, renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood bicarbonate decreased, blood creatinine increased, blood glucose increased, haematocrit decreased, haemoglobin decreased, lymphocyte count decreased, mean cell haemoglobin decreased, monocyte count decreased. Rapamune dosage: 3 MG 1X PER 1 DAY. During the same period patient was treated with ASPIRIN, CANDESARTAN, LEVOTHYROXINE, NIFEDIPINE, ATORVASTATIN CALCIUM, INSULATARD. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4677713-X
Rapamune side effect was reported by a Consumer or non-health professional from on May 23, 2003. Female patient, 52 years of age, was diagnosed with immunosuppression, renal transplant and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood bicarbonate decreased, blood creatinine increased, blood glucose increased, bronchitis

, c-reactive protein increased, dyspnoea, haematocrit decreased. Rapamune dosage: 3 MG 1X PER 1 DAY ORAL. During the same period patient was treated with ASPIRIN, CANDESARTAN, THYROXINE, NIFEDIPINE, ATORVASTATIN CALCIUM, INSULATARD. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #5129278-6
Rapamune side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 02, 2006. Male patient, 51 years of age, was diagnosed with immunosuppression and was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, hyperkalaemia, international normalised ratio increased, leukoencephalopathy, optic ischaemic neuropathy. Rapamune dosage: 2 MG 1X PER 1 DAY, ORAL. During the same period patient was treated with TACROLIMUS, ALENDRONATE, CALCICHEW, CALCIUM RESONIUM, CODEINE SUL, CREON, FLUCONAZOLE, GABAPENTIN. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4785635-9
Rapamune side effect was reported by a Consumer or non-health professional from SWITZERLAND on Sept 16, 2005. Male patient, 35 years of age, was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, graft versus host disease, hepatocellular damage, hypertriglyceridaemia, hypokalaemia. Rapamune dosage: 1 MG 1X PER 1 DAY ORAL - SEE IMAGE. During the same period patient was treated with FOLIC ACID, PANTOZOL, BACTRIM PORTE, DIFLUCAN, MAGNESIOCARD. Patient was hospitalized. Patient recovered.

Rapamune Side Effects Report #4804748-6
Rapamune side effect was reported by a Consumer or non-health professional from SWITZERLAND on Oct 06, 2005. Male patient, 35 years of age, was treated with Rapamune. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, graft versus host disease, hepatic trauma, hepatocellular damage, hypertriglyceridaemia. Rapamune dosage: unknown. During the same period patient was treated with FOLIC ACID, PANTOZOL, BACTRIM DS, DIFLUCAN, MAGNESIOCARD. Patient was hospitalized. Patient recovered.

Rapamune and blood alkaline phosphatase increased

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Rapamune and blood alkaline phosphatase increased Patient Reports February 11, 2012

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