Raltegravir and cholestasis Patient Reports February 12, 2012

Raltegravir Side Effects Report #5636880-1
Raltegravir side effect was reported by a Physician from AUSTRALIA on Feb 13, 2008. Male patient, 45 years of age, was diagnosed with hiv infection , castleman's disease and was treated with Raltegravir. After drug was administered, patient experienced the following side effects: abdominal distension, cholestasis, hepatic necrosis, hepatosplenomegaly, hyperglycaemia, immune reconstitution syndrome. Raltegravir dosage: 400 MG/BID; PO. During the same period patient was treated with ETRAVIRINE, DEXAMETHASONE, DARUNAVIR, LAMIVUDINE, RITONAVIR, TENOFOVIR. Patient was hospitalized. Patient died.

Raltegravir Side Effects Report #5772133-9
Raltegravir side effect was reported by a Health Professional from FRANCE on June 05, 2008. Male patient, 45 years of age, was diagnosed with hiv infection , liver transplant  and was treated with Raltegravir. After drug was administered, patient experienced the following side effects: cd4 lymphocytes decreased, cholestasis, hepatitis c , myelocytosis, renal failure. Raltegravir dosage: unknown. During the same period patient was treated with DARUNAVIR, RITONAVIR, ENFUVIRTIDE, TACROLIMUS, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.