Pyrazinamide and cytolytic hepatitis Patient Reports February 13, 2012

Pyrazinamide Side Effects Report #5005674-2
Pyrazinamide side effect was reported by a Consumer or non-health professional from on May 10, 2006. Male patient, 39 years of age, was diagnosed with tuberculosis  and was treated with Pyrazinamide. After drug was administered, patient experienced the following side effects: ascites, bone tuberculosis, coagulopathy, cytolytic hepatitis, fistula , hepatic atrophy, hepatic encephalopathy, hepatic failure, hepatic necrosis. Pyrazinamide dosage: 1800MG/DAY. During the same period patient was treated with ISONIAZID, RIFAMPIN, STREPTOMYCIN, CIPROFLOXACIN, ETHAMBUTOL, TRAMADOL. Patient was hospitalized. Patient recovered.

Pyrazinamide Side Effects Report #4695655-0
Pyrazinamide side effect was reported by a Consumer or non-health professional from on June 08, 2005. Female patient, 75 years of age, was diagnosed with bone tuberculosis and was treated with Pyrazinamide. After drug was administered, patient experienced the following side effects: cholestasis, cytolytic hepatitis, dermatitis allergic, eosinophilia, hepatic failure, liver disorder, pyrexia, skin exfoliation. Pyrazinamide dosage: unknown. During the same period patient was treated with RIFADIN, RIMIFON, AUGMENTIN, OFLOCET, ROCEPHIN, RULID, ORELOX, TAVANIC. Patient was hospitalized. Patient recovered.