Protamine and post procedural complication Patient Reports February 12, 2012

Protamine Side Effects Report #4701727-4
Protamine side effect was reported by a Physician from on Apr 26, 2005. Female patient, 66 years of age, weighting 207.2 lb, was diagnosed with haemorrhage, off label use and was treated with Protamine. After drug was administered, patient experienced the following side effects: bacteraemia, enterobacter infection, fungal infection , multi-organ failure, pneumonia , portal vein thrombosis, post procedural complication, stenotrophomonas infection, systemic candida. Protamine dosage: unknown. During the same period patient was treated with NIASTASE. Patient was hospitalized. Patient recovered.

Protamine Side Effects Report #4819509-1
Protamine side effect was reported by a Pharmacist from UNITED STATES on Nov 02, 2005. Female patient, 39 years of age, weighting 154.0 lb, was diagnosed with coagulopathy and was treated with Protamine. After drug was administered, patient experienced the following side effects: bronchospasm, dyspnoea, post procedural complication. Protamine dosage: unknown. Patient recovered.

Protamine Side Effects Report #5120973-1
Protamine side effect was reported by a Pharmacist from UNITED STATES on Oct 03, 2006. Male patient, 61 years of age, was treated with Protamine. After drug was administered, patient experienced the following side effects: blood pressure decreased, cardiac arrest , post procedural complication. Protamine dosage: 50 MG IV ONCE. Patient was hospitalized. Patient recovered.

Protamine Side Effects Report #5329870-X
Protamine side effect was reported by a Pharmacist from UNITED STATES on May 17, 2007. Male patient, 60 years of age, weighting 205.0 lb, was treated with Protamine. After drug was administered, patient experienced the following side effects: anaphylactic reaction, hypotension, post procedural complication, pulmonary oedema, respiratory distress. Protamine dosage: 420 MG ONCE IV BOLUS. Patient died on 02/23/2007.


Protamine Side Effects Report #5189106-X
Protamine side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 08, 2006. Female patient, child 3 years of age, weighting 27.78 lb, was treated with Protamine. After drug was administered, patient experienced the following side effects: blood pressure decreased, post procedural complication, pulmonary hypertension , sinus tachycardia. Protamine dosage: (75 MG, ONCE), INTRAVENOUS. During the same period patient was treated with SEVOFLURANE, PANCURONIUM, CEFAZOLIN, METHYLPREDNISOLONE, FENTANYL, ISOFLURANE, HEPARIN. Patient was hospitalized. Patient recovered.