Protamine and bradycardia Patient Reports February 12, 2012

Protamine Side Effects Report #4783229-2
Protamine side effect was reported by a Pharmacist from UNITED STATES on Sept 28, 2005. Female patient, 66 years of age, weighting 197.0 lb, was diagnosed with infusion, skin disorder and was treated with Protamine. After drug was administered, patient experienced the following side effects: angioneurotic oedema, bradycardia, hypotension, procedural complication. Protamine dosage: 50 MG IV X 1. During the same period patient was treated with MARCAINE, TOPROL, PLAVIX, NIACIN. Patient recovered.

Protamine Side Effects Report #5333125-7
Protamine side effect was reported by a Pharmacist from UNITED STATES on May 21, 2007. Male patient, 65 years of age, was treated with Protamine. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest , procedural complication, procedural hypotension. Protamine dosage: 50 MG ONE TIME ORDER IV. Patient recovered.

Protamine Side Effects Report #5232825-7
Protamine side effect was reported by a Pharmacist from UNITED STATES on Feb 06, 2007. Female patient, 55 years of age, was treated with Protamine. After drug was administered, patient experienced the following side effects: bradycardia, cardio-respiratory arrest, convulsion, procedural complication, procedural hypotension. Protamine dosage: 50 MG X1 IV. During the same period patient was treated with PROTAMINE SULPHATE. Patient was hospitalized and became disabled. Patient recovered.

Protamine Side Effects Report #5205856-0
Protamine side effect was reported by a Pharmacist from UNITED STATES on Jan 05, 2007. Female patient, child 3 years of age, weighting 32.85 lb, was diagnosed with surgery  and was treated with Protamine. After drug was administered, patient experienced the following side effects: bradycardia, cerebral artery embolism, dialysis , hypotension, procedural complication, pulmonary hypertension , renal failure, systemic mycosis. Protamine dosage: 15 MG -1.5 ML- 1 DOSE IV BOLUS. During the same period patient was treated with PROTAMINE SULPHATE, MIDAZOLAM HYDROCHLORIDE, FENTANYL TRANSDERMAL SYSTEM, MORPHINE, PANCURONIUM, VECURONIUM BROMIDE, HEPARIN, AMINOCAPROIC ACID. Patient died on 12/14/2006.