Propofol and rhabdomyolysis Patient Reports February 11, 2012

Propofol Side Effects Report #5075609-5
Propofol side effect was reported by a Health Professional from UNITED KINGDOM on Aug 03, 2006. Male patient, 51 years of age, weighting 176.4 lb, was diagnosed with subdural haemorrhage, hypertension, blood cholesterol increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, myoglobinuria, renal failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with AMLODIPINE, ANADIN, ATORVASTATIN CALCIUM, RAMIPRIL, WARFARIN. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5787454-3
Propofol side effect was reported by a Health Professional from UNITED STATES on June 11, 2008. Male patient, 64 years of age, was diagnosed with status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: anoxic encephalopathy, dyslipidaemia, propofol infusion syndrome, renal failure acute, rhabdomyolysis, shock. Propofol dosage: 1 MG/KG, ONCE, INTRAVENOUS BOLUS; 120-140 UG/KG/MIN, INFUSION. During the same period patient was treated with LORAZEPAM, PHENYTOIN, ZONISAMIDE, FOSPHENYTOIN, INTRAVENOUS FLUIDS, NOREPINEPHRINE BITARTRATE. Patient died.

Propofol Side Effects Report #4893795-4
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Male patient, 64 years of age, was diagnosed with status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: hypotension, metabolic acidosis, rhabdomyolysis. Propofol dosage: unknown. Patient died.

Propofol Side Effects Report #4940115-2
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Male patient, 63 years of age, weighting 154.3 lb, was diagnosed with status epilepticus, grand mal convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: hypotension, metabolic acidosis, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with FOSPHENYTOIN. Patient died.

Propofol Side Effects Report #4689137-X
Propofol side effect was reported by a Physician from on May 31, 2005. Male patient, child 7 years of age, was diagnosed with sedation, anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, injury, lactic acidosis, procedural complication, rhabdomyolysis. Propofol dosage: TOTAL DOSE 6.1 MG/KG BW). During the same period patient was treated with THIOPENTAL, MIVACURIUM, FENTANYL, SEVOFLURANE. Patient recovered.

Propofol Side Effects Report #5413147-8
Propofol side effect was reported by a Physician from UNITED STATES on Aug 01, 2007. Male patient, 66 years of age, was diagnosed with sedation, polymyositis, immunosuppression, hyperlipidaemia and was treated with Propofol. After drug was administered, patient experienced the following side effects: haemodialysis, hyporeflexia, oliguria, pneumonia

, respiratory distress, rhabdomyolysis, septic shock, weight decreased. Propofol dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, PREDNISONE, CYCLOSPORINE, SIMVASTATIN, COLCHICUM JTL LIQ, MYCOPHENOLATE, INSULIN. Patient was hospitalized. Patient died.

Propofol Side Effects Report #5590556-8
Propofol side effect was reported by a Physician from UNITED STATES on Dec 11, 2007. Male patient, 66 years of age, was diagnosed with sedation, polymyositis, immunosuppression and was treated with Propofol. After drug was administered, patient experienced the following side effects: haemodialysis, hyporeflexia, mitochondrial myopathy, myopathy toxic, oliguria, pneumonia

, respiratory distress, rhabdomyolysis, septic shock. Propofol dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, MYCOPHENOLATE, PREDNISONE, CYCLOSPORINE, SIMVASTATIN, COLCHICUM JTL LIQ, INSULIN. Patient was hospitalized. Patient died.

Propofol Side Effects Report #5688082-0
Propofol side effect was reported by a Physician from UNITED STATES on Mar 17, 2008. Male patient, 66 years of age, was diagnosed with sedation, heart transplant

, muscular weakness, gout

and was treated with Propofol. After drug was administered, patient experienced the following side effects: gout

, muscular weakness, gout

and was treated with Propofol. After drug was administered, patient experienced the following side effects: gout

, mitochondrial myopathy acquired, myopathy toxic, respiratory failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHYLPREDNISOLONE, SIMVASTATIN, COLCHICINE, PREDNISONE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient died.

Propofol Side Effects Report #5754162-4
Propofol side effect was reported by a Physician from ISRAEL on May 28, 2008. Male patient, 52 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: hyperbilirubinaemia, hypertriglyceridaemia, metabolic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with ATRACRIUM. Patient recovered.

Propofol Side Effects Report #4920026-9
Propofol side effect was reported by a Health Professional from NETHERLANDS on Dec 14, 2000. Male patient, 44 years of age, was diagnosed with sedation, intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradyarrhythmia, cardiac arrest

, hyperkalaemia, hypotension, intracranial pressure increased, metabolic acidosis, pyrexia, rhabdomyolysis, tachycardia. Propofol dosage: unknown. During the same period patient was treated with MANNITOL. Patient was hospitalized. Patient died.

Propofol Side Effects Report #5585358-2
Propofol side effect was reported by a Pharmacist from UNITED STATES on Jan 04, 2008. Female patient, 37 years of age, weighting 145.5 lb, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: aneurysm ruptured, blood creatinine increased, blood lactic acid increased, cardiac arrest

, hypotension, operative haemorrhage, rhabdomyolysis, ventricular tachycardia. Propofol dosage: unknown. During the same period patient was treated with SENNA, SIMVASTATIN, BISACODYL, KEPPRA, NIMODIPINE, PREVACID, HEPARIN, CEFEPIME. Patient died on 10/15/2007.

Propofol Side Effects Report #5236396-0
Propofol side effect was reported by a Consumer or non-health professional from FRANCE on Jan 25, 2007. Female patient, child 3 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiac disorder, cardiac failure, metabolic acidosis, rhabdomyolysis. Propofol dosage: VARIABLE WITH MAXIMAL FLOW AT 100 MG/HOUR, INTRAVENOUS. Patient died.

Propofol Side Effects Report #4639132-1
Propofol side effect was reported by a Physician from on Mar 31, 2005. Female patient, 29 years of age, weighting 154.3 lb, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia

, myocardial infarction, myopathy, propofol infusion syndrome, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with NORADRENALINE, CORTICOSTEROIDS, TAZOCEL, LINEZOLID, EPTACOG. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5142995-7
Propofol side effect was reported by a Physician from SWITZERLAND on Oct 30, 2006. Male patient, 24 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, brain oedema, hyperkalaemia, propofol infusion syndrome, renal failure acute, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE. Patient died.

Propofol Side Effects Report #4928597-3
Propofol side effect was reported by a Health Professional from NETHERLANDS on Dec 14, 2000. Male patient, 24 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, cardiac arrest

, hyperkalaemia, lung infiltration, metabolic acidosis, rhabdomyolysis, ventricular arrhythmia. Propofol dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient was hospitalized. Patient died.

Propofol Side Effects Report #5921009-2
Propofol side effect was reported by a Health Professional from GREECE on Oct 13, 2008. Male patient, 20 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: propofol infusion syndrome, renal failure acute, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with REMIFENTANYL, MEROPENEM, GENTAMYCIN SULPHATE, TEICOPLANIN. Patient recovered.

Propofol Side Effects Report #5400477-9
Propofol side effect was reported by a Health Professional from UNITED STATES on July 24, 2007. Male patient, 16 years of age, was diagnosed with sedation, intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia

, circulatory collapse, metabolic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis, tachycardia. Propofol dosage: unknown. Patient died.

Propofol Side Effects Report #4700499-7
Propofol side effect was reported by a Health Professional from on June 20, 2005. Female patient, 16 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: acidosis, fluid overload, haemodialysis, hepatic steatosis, medium-chain acetyl-coenzyme a dehydrogenase deficiency, renal failure, rhabdomyolysis, ventricular dysfunction. Propofol dosage: unknown. During the same period patient was treated with MORPHINE, MIDAZOLAM. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #4921604-3
Propofol side effect was reported by a Health Professional from NETHERLANDS on Feb 13, 2003. Male patient, 15 years of age, was diagnosed with sedation, cerebral disorder and was treated with Propofol. After drug was administered, patient experienced the following side effects: electrocardiogram st segment elevation, renal failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with DOPAMINE, NOREPINEPHRINE, MANNITOL. Patient recovered.

Propofol Side Effects Report #4939167-5
Propofol side effect was reported by a Health Professional from NETHERLANDS on Feb 13, 2006. Male patient, 15 years of age, was diagnosed with sedation, cerebral disorder and was treated with Propofol. After drug was administered, patient experienced the following side effects: electrocardiogram st segment elevation, renal failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with DOPAMINE, NOREPINEPHRINE, MANNITOL. Patient recovered.

Propofol Side Effects Report #5360750-X
Propofol side effect was reported by a Health Professional from UNITED STATES on June 11, 2007. Female patient, 36 years of age, was diagnosed with intubation, sedation, status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiomyopathy

, lactic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with TOPIRAMATE, BENZODIAZEPINES, PHENOBARBITAL. Patient died.

Propofol Side Effects Report #4928602-4
Propofol side effect was reported by a Health Professional from LEBANON on Feb 22, 2006. Female patient, 36 years of age, was diagnosed with intubation, sedation, status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiomyopathy

, lactic acidosis, propofol infusion syndrome, renal failure, rhabdomyolysis. Propofol dosage: INTIAL DOSE INCREASED THEN DECREASED BUT ALWAYS { 5MG/KG/HR. During the same period patient was treated with TOPIRAMATE, BENZODIAZEPINES, PHENOBARBITAL, VALPROIC ACID. Patient died.

Propofol Side Effects Report #4608627-9
Propofol side effect was reported by a Pharmacist from on Mar 11, 2005. Female patient, 32 years of age, weighting 156.5 lb, was diagnosed with intracranial pressure increased, sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: atrioventricular block, cardiac failure, hyperkalaemia, hypertriglyceridaemia, metabolic acidosis, peripheral ischaemia, procedural complication, rhabdomyolysis, ventricular arrhythmia. Propofol dosage: unknown. Patient died on 02/28/2005.

Propofol Side Effects Report #6062537-1
Propofol side effect was reported by a Physician from SWITZERLAND on Jan 14, 2009. Male patient, 37 years of age, weighting 165.3 lb, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: haemodialysis, hyperthermia malignant, rhabdomyolysis. Propofol dosage: 2 MG/KG;. During the same period patient was treated with FENTANYL, SEVOFLURANE, DICLOFENAC. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5455737-2
Propofol side effect was reported by a Physician from UNITED STATES on Sept 05, 2007. Female patient, 29 years of age, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: circulatory collapse, haemodynamic instability, hypotension, metabolic acidosis, no therapeutic response, propofol infusion syndrome, rhabdomyolysis. Propofol dosage: 4 - 12 MG/KG/H, INFUSION. During the same period patient was treated with NEUROMUSCULAR BLOCKER, MANNITOL, EPINEPHRINE. Patient died.

Propofol Side Effects Report #5799983-7
Propofol side effect was reported by a Health Professional from UNITED STATES on June 20, 2008. Male patient, 64 years of age, was diagnosed with convulsion, status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: dyslipidaemia, hyperkalaemia, hypotension, lactic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis, shock. Propofol dosage: unknown. During the same period patient was treated with FOSPHENYTOIN. Patient died.

Propofol Side Effects Report #5061293-3
Propofol side effect was reported by a Pharmacist from UNITED STATES on July 21, 2006. Male patient, 24 years of age, weighting 150.4 lb, was diagnosed with coma, convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: acidosis, arrhythmia

, blood methaemoglobin present, cardio-respiratory arrest, hypotension, metabolic acidosis, rhabdomyolysis, tachycardia. Propofol dosage: 2MG/KG LOAD, 0.1MG/KG/MIN MAINTENANCE *TITRATED TO BURST SUPPRESSION. During the same period patient was treated with TRANXENE, PEPCID, KEPPRA, SINEMET, MIRAPEX, VARIOUS PRESSORS. Patient died on 06/08/2006.

Propofol Side Effects Report #4694817-6
Propofol side effect was reported by a Physician from on June 06, 2005. Male patient, 42 years of age, weighting 169.8 lb, was diagnosed with anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, hypertension, lactic acidosis, myoglobinuria, procedural hypertension, propofol infusion syndrome, renal impairment, rhabdomyolysis. Propofol dosage: 5.2 MG KG^-1 H^-1. During the same period patient was treated with METHYLPREDNISOLONE, SEVOFLURANE, HETASTARCH IN CHLORIDE. Patient recovered.

Propofol Side Effects Report #5307274-3
Propofol side effect was reported by a Pharmacist from UNITED STATES on Apr 23, 2007. Male patient, 18 years of age, weighting 275.6 lb, was diagnosed with acute respiratory distress syndrome, treatment failure and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, haemodialysis, oxygen saturation decreased, renal failure acute, rhabdomyolysis. Propofol dosage: 34,000 MG IN 4-5 DAYS ~ 3-5 MG/KG/HR. During the same period patient was treated with MIDAZOLAM DRIP, FENTANYL DRIP, REGLAN, NEXIUM. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5255458-5
Propofol side effect was reported by a Health Professional from ITALY on Feb 22, 2007. Female patient, 62 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: acidosis, aspartate aminotransferase increased, blood lactate dehydrogenase increased, hypotension, renal failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with FENTANEST. Patient recovered.

Propofol Side Effects Report #4838123-5
Propofol side effect was reported by a Health Professional from GERMANY on Nov 21, 2005. Male patient, 44 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia

, arthralgia, cardiac arrest

, haemodialysis, oliguria, renal failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with SUCCINYLCHOLINE CHLORIDE, ESMERON, FENTANYL. Patient died.

Propofol Side Effects Report #5169054-1
Propofol side effect was reported by a Health Professional from POLAND on Dec 04, 2006. Female patient, child 4 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: hepatomegaly, hyperkalaemia, hypotension, international normalised ratio increased, lipids abnormal, metabolic acidosis, propofol infusion syndrome, rhabdomyolysis, tachycardia. Propofol dosage: unknown. Patient died.

Propofol Side Effects Report #5067928-3
Propofol side effect was reported by a Health Professional from UNITED KINGDOM on July 21, 2006. Male patient, 29 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with FENTANYL, SUCCINYLCHOLINE CHLORIDE, RABEPRAZOLE, INHALERS. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5455735-9
Propofol side effect was reported by a Physician from UNITED STATES on Sept 05, 2007. Male patient, 18 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: anuria, arrhythmia

, circulatory collapse, metabolic acidosis, propofol infusion syndrome, rhabdomyolysis. Propofol dosage: INC DOSE MAX OF 7.5 MG/KG/H, INFUSION. During the same period patient was treated with MORPHINE, VASOPRESSOR. Patient died.

Propofol Side Effects Report #4580135-3
Propofol side effect was reported by a Consumer or non-health professional from on Feb 04, 2005. Male patient, 17 years of age, weighting 143.3 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest

, hyperkalaemia, hypotension, metabolic acidosis, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with MORPHINE HYDROCHLORIDE, MIDAZOLAM. Patient recovered.

Propofol Side Effects Report #5049483-7
Propofol side effect was reported by a Health Professional from SPAIN on July 06, 2006. Male patient was diagnosed with pneumonia

and was treated with Propofol. After drug was administered, patient experienced the following side effects: hyperkalaemia, pyrexia, renal failure acute, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with HYDROCORTISONE, MIDAZOLAM, MORPHINE, NORADRENALINE, INSULIN, RANITIDINE, CLEXANE. Patient was hospitalized. Patient died on 05/20/2006.

Propofol Side Effects Report #5731949-5
Propofol side effect was reported by a Pharmacist from UNITED STATES on Apr 30, 2008. Male patient was diagnosed with septic shock and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, cardiogenic shock, rhabdomyolysis. Propofol dosage: 3 TO 4 MG/KG/HOUR. During the same period patient was treated with OMEPRAZOLE, TAZOCILLINE, FUROSEMIDE, REMIFENTANIL. Patient was hospitalized. Patient recovered.

Propofol and rhabdomyolysis

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Propofol and rhabdomyolysis Patient Reports February 11, 2012

side effects of Propofol