Propofol and metabolic acidosis 
Propofol and metabolic acidosis Patient Reports February 11, 2012
Propofol Side Effects Report #5977568-7
Propofol side effect was reported by a Physician from UNITED STATES on Nov 11, 2008. Female patient, 33 years of age, was diagnosed with subarachnoid haemorrhage, subdural haematoma and was treated with Propofol. After drug was administered, patient experienced the following side effects: atrioventricular block first degree, blood triglycerides increased, bundle branch block left, bundle branch block right, cardiac arrest
, metabolic acidosis, propofol infusion syndrome. Propofol dosage: unknown. Patient was hospitalized. Patient died.Propofol Side Effects Report #4893795-4
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Male patient, 64 years of age, was diagnosed with status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: hypotension, metabolic acidosis, rhabdomyolysis. Propofol dosage: unknown. Patient died.
Propofol Side Effects Report #4940115-2
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Male patient, 63 years of age, weighting 154.3 lb, was diagnosed with status epilepticus, grand mal convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: hypotension, metabolic acidosis, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with FOSPHENYTOIN. Patient died.
Propofol Side Effects Report #5113662-0
Propofol side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 21, 2006. Male patient, weighting 234.8 lb, was diagnosed with status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, cardiac arrest
, metabolic acidosis, propofol infusion syndrome, ventricular tachycardia. Propofol dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, INSULIN, DEXAMETHASONE, LAMOTRIGINE, PENICILLIN G POTASSIUM, PHENOBARBITAL, PHENYTOIN, RANITIDINE. Patient died on 02/15/2006.Propofol Side Effects Report #4987873-9
Propofol side effect was reported by a Pharmacist from UNITED STATES on Apr 27, 2006. Female patient, 58 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: metabolic acidosis. Propofol dosage: unknown. Patient was hospitalized. Patient recovered.
Propofol Side Effects Report #5754162-4
Propofol side effect was reported by a Physician from ISRAEL on May 28, 2008. Male patient, 52 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: hyperbilirubinaemia, hypertriglyceridaemia, metabolic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with ATRACRIUM. Patient recovered.
Propofol Side Effects Report #4920026-9
Propofol side effect was reported by a Health Professional from NETHERLANDS on Dec 14, 2000. Male patient, 44 years of age, was diagnosed with sedation, intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradyarrhythmia, cardiac arrest
, hyperkalaemia, hypotension, intracranial pressure increased, metabolic acidosis, pyrexia, rhabdomyolysis, tachycardia. Propofol dosage: unknown. During the same period patient was treated with MANNITOL. Patient was hospitalized. Patient died.Propofol Side Effects Report #5332457-6
Propofol side effect was reported by a Health Professional from GREECE on May 14, 2007. Female patient, 35 years of age, was diagnosed with sedation, metabolic abnormality management, prophylaxis and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiomyopathy
, hyperkalaemia, hyperlipidaemia, metabolic acidosis, muscle injury, propofol infusion syndrome, renal failure acute. Propofol dosage: 2%, 25-30 ML/HR. During the same period patient was treated with VASOPRESSORS, REMIFENTANIL. Patient recovered.Propofol Side Effects Report #5799976-X
Propofol side effect was reported by a Health Professional from UNITED STATES on June 20, 2008. Female patient, 33 years of age, was diagnosed with sedation, intracranial pressure increased, analgesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: atrioventricular block first degree, blood triglycerides increased, bundle branch block left, bundle branch block right, cardiac arrest
, hypotension, metabolic acidosis, propofol infusion syndrome, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with MORPHINE. Patient died.Propofol Side Effects Report #4918674-5
Propofol side effect was reported by a Health Professional from NETHERLANDS on Dec 14, 2000. Female patient, 31 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia
, brain herniation, cardiovascular disorder, hyperkalaemia, hyperlipidaemia, metabolic acidosis. Propofol dosage: unknown. Patient was hospitalized. Patient died.Propofol Side Effects Report #5236396-0
Propofol side effect was reported by a Consumer or non-health professional from FRANCE on Jan 25, 2007. Female patient, child 3 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiac disorder, cardiac failure, metabolic acidosis, rhabdomyolysis. Propofol dosage: VARIABLE WITH MAXIMAL FLOW AT 100 MG/HOUR, INTRAVENOUS. Patient died.
Propofol Side Effects Report #5999704-9
Propofol side effect was reported by a Health Professional from UNITED STATES on Dec 10, 2008. Male patient, 28 years of age, was diagnosed with sedation, intracranial pressure increased, cerebral hypoperfusion and was treated with Propofol. After drug was administered, patient experienced the following side effects: ejection fraction decreased, electrocardiogram qt prolonged, electrocardiogram t wave inversion, metabolic acidosis, propofol infusion syndrome. Propofol dosage: unknown. During the same period patient was treated with PHENYLEPHRINE. Patient recovered.
Propofol Side Effects Report #4940081-X
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Female patient, 27 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, hyperkalaemia, hypotension, metabolic acidosis, myocardial ischaemia. Propofol dosage: unknown. Patient died.
Propofol Side Effects Report #4612680-6
Propofol side effect was reported by a Pharmacist from on Mar 16, 2005. Male patient, 26 years of age, weighting 187.4 lb, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: airway complication of anaesthesia, arrhythmia
, electrocardiogram qrs complex prolonged, electrocardiogram t wave abnormal, hyperkalaemia, metabolic acidosis, post procedural cellulitis, post procedural complication, retropharyngeal abscess. Propofol dosage: unknown. During the same period patient was treated with FENTANYL, CLINDAMYCIN, CEFEPIME. Patient was hospitalized. Patient recovered.Propofol Side Effects Report #4928597-3
Propofol side effect was reported by a Health Professional from NETHERLANDS on Dec 14, 2000. Male patient, 24 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, cardiac arrest
, hyperkalaemia, lung infiltration, metabolic acidosis, rhabdomyolysis, ventricular arrhythmia. Propofol dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient was hospitalized. Patient died.Propofol Side Effects Report #5975405-8
Propofol side effect was reported by a Health Professional from GERMANY on Nov 24, 2008. Female patient, 23 years of age, weighting 101.4 lb, was diagnosed with sedation, bronchoscopy and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, cardiogenic shock, cardiovascular insufficiency, hypoventilation, left ventricular failure, metabolic acidosis, oxygen saturation decreased. Propofol dosage: unknown. During the same period patient was treated with MIDAZOLAM. Patient was hospitalized. Patient recovered.
Propofol Side Effects Report #5004139-1
Propofol side effect was reported by a Health Professional from UNITED STATES on May 11, 2006. Male patient, 21 years of age, was diagnosed with sedation, reduction of increased intracranial pressure and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiomyopathy
, lactic acidosis, metabolic acidosis, propofol infusion syndrome, ventricular dysfunction. Propofol dosage: unknown. During the same period patient was treated with DOPAMINE, NOREPINEPHRINE. Patient recovered.Propofol Side Effects Report #5652652-6
Propofol side effect was reported by a Pharmacist from UNITED STATES on Mar 05, 2008. Male patient, 18 years of age, weighting 156.5 lb, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: electrocardiogram change, metabolic acidosis, propofol infusion syndrome. Propofol dosage: 100ML RATE VARIES IV DRIP. Patient died on 01/26/2008.
Propofol Side Effects Report #4918664-2
Propofol side effect was reported by a Health Professional from NETHERLANDS on Dec 14, 2000. Male patient, 17 years of age, was diagnosed with sedation, intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: atrial fibrillation
, cardiac arrest , cardiovascular disorder, hyperkalaemia, hyperlipidaemia, lung infiltration, metabolic acidosis, renal impairment, ventricular arrhythmia. Propofol dosage: unknown. During the same period patient was treated with MANNITOL. Patient was hospitalized. Patient died.Propofol Side Effects Report #5400477-9
Propofol side effect was reported by a Health Professional from UNITED STATES on July 24, 2007. Male patient, 16 years of age, was diagnosed with sedation, intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia
, circulatory collapse, metabolic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis, tachycardia. Propofol dosage: unknown. Patient died.Propofol Side Effects Report #5415679-5
Propofol side effect was reported by a Physician from UNITED STATES on Aug 07, 2007. Male patient, 16 years of age, was diagnosed with sedation, intracranial pressure increased, ill-defined disorder and was treated with Propofol. After drug was administered, patient experienced the following side effects: arrhythmia
, circulatory collapse, metabolic acidosis, propofol infusion syndrome, renal failure acute, rhabdomyolysis, tachycardia. Propofol dosage: unknown. Patient died.Propofol Side Effects Report #4908988-7
Propofol side effect was reported by a Pharmacist from UNITED STATES on Feb 10, 2006. Female patient, 84 years of age, weighting 149.9 lb, was diagnosed with life support and was treated with Propofol. After drug was administered, patient experienced the following side effects: metabolic acidosis. Propofol dosage: 100ML PRN IV DRIP. Patient recovered.
Propofol Side Effects Report #6130505-7
Propofol side effect was reported by a Health Professional from UNITED STATES on Mar 12, 2009. Male patient, 38 years of age, was diagnosed with intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiac enzymes increased, ejection fraction abnormal, electrocardiogram st segment elevation, metabolic acidosis, propofol infusion syndrome, tachyarrhythmia, ventricular tachycardia. Propofol dosage: unknown. During the same period patient was treated with DOPAMINE, PHENYLEPHRINE USP, MANNITOL, SALINE. Patient recovered.
Propofol Side Effects Report #4608627-9
Propofol side effect was reported by a Pharmacist from on Mar 11, 2005. Female patient, 32 years of age, weighting 156.5 lb, was diagnosed with intracranial pressure increased, sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: atrioventricular block, cardiac failure, hyperkalaemia, hypertriglyceridaemia, metabolic acidosis, peripheral ischaemia, procedural complication, rhabdomyolysis, ventricular arrhythmia. Propofol dosage: unknown. Patient died on 02/28/2005.
Propofol Side Effects Report #5993326-1
Propofol side effect was reported by a Health Professional from UNITED STATES on Dec 10, 2008. Male patient, 25 years of age, was diagnosed with intracranial pressure increased, cerebral hypoperfusion, csf pressure and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, electrocardiogram t wave inversion, metabolic acidosis, propofol infusion syndrome. Propofol dosage: unknown. During the same period patient was treated with PHENYLEPHRINE, PENTOBARBITAL CAP, THIOPENTAL. Patient died.
Propofol Side Effects Report #5455737-2
Propofol side effect was reported by a Physician from UNITED STATES on Sept 05, 2007. Female patient, 29 years of age, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: circulatory collapse, haemodynamic instability, hypotension, metabolic acidosis, no therapeutic response, propofol infusion syndrome, rhabdomyolysis. Propofol dosage: 4 - 12 MG/KG/H, INFUSION. During the same period patient was treated with NEUROMUSCULAR BLOCKER, MANNITOL, EPINEPHRINE. Patient died.
Propofol Side Effects Report #5042691-0
Propofol side effect was reported by a Health Professional from JAPAN on May 31, 2006. Male patient, 22 years of age, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood calcium increased, blood creatine phosphokinase increased, hepatic function abnormal, hyperthermia malignant, metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with SUXAMETHONIUM CHLORIDE, OXYGEN, SEVOFLURANE, FENTANYL CITRATE. Patient recovered.
Propofol Side Effects Report #5021188-8
Propofol side effect was reported by a Health Professional from JAPAN on May 31, 2006. Male patient, 22 years of age, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: hyperthermia malignant, metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with SUXAMETHONIUM CHLORIDE, OXYGEN, SEVOFLURANE, FENTANYL CITRATE. Patient recovered.
Propofol Side Effects Report #4893794-2
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Female patient, 24 years of age, was diagnosed with convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradyarrhythmia, hypotension, metabolic acidosis. Propofol dosage: unknown. Patient died.
Propofol Side Effects Report #4940059-6
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Female patient, 24 years of age, weighting 121.3 lb, was diagnosed with convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest
, cardiac pacemaker malfunction, electromechanical dissociation, hyperkalaemia, hypotension, metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with FOSPHENYTOIN, MIDAZOLAM, PHENOBARBITAL. Patient died.Propofol Side Effects Report #4893790-5
Propofol side effect was reported by a Health Professional from UNITED STATES on Jan 24, 2006. Female patient, 27 years of age, was diagnosed with coma and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, hypotension, metabolic acidosis. Propofol dosage: unknown. Patient died.
Propofol Side Effects Report #5061293-3
Propofol side effect was reported by a Pharmacist from UNITED STATES on July 21, 2006. Male patient, 24 years of age, weighting 150.4 lb, was diagnosed with coma, convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: acidosis, arrhythmia
, blood methaemoglobin present, cardio-respiratory arrest, hypotension, metabolic acidosis, rhabdomyolysis, tachycardia. Propofol dosage: 2MG/KG LOAD, 0.1MG/KG/MIN MAINTENANCE *TITRATED TO BURST SUPPRESSION. During the same period patient was treated with TRANXENE, PEPCID, KEPPRA, SINEMET, MIRAPEX, VARIOUS PRESSORS. Patient died on 06/08/2006.Propofol Side Effects Report #5288401-3
Propofol side effect was reported by a Health Professional from UNITED STATES on Apr 02, 2007. Female patient, child 3 years of age, was diagnosed with angiogram and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiac failure, hypotension, metabolic acidosis, overdose, propofol infusion syndrome, tachycardia. Propofol dosage: unknown. Patient recovered.
Propofol Side Effects Report #4656773-6
Propofol side effect was reported by a Consumer or non-health professional from on Apr 25, 2005. Female patient, 68 years of age, was diagnosed with anaesthesia, sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: brain stem auditory evoked response abnormal, cardiac arrest
, cardiovascular disorder, electrocardiogram st segment abnormal, electroencephalogram abnormal, hypertension, metabolic acidosis, post procedural complication, ventricular fibrillation. Propofol dosage: unknown. During the same period patient was treated with ALFENTANIL, ISOFLURANE, PANCURONIUM, NITROPRUSSIDE, NITROGLYCERIN A. Patient recovered.Propofol Side Effects Report #5239653-7
Propofol side effect was reported by a Physician from UNITED KINGDOM on Feb 05, 2007. Female patient, 32 years of age, was diagnosed with anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: metabolic acidosis. Propofol dosage: 3 - 5 UG/ML. During the same period patient was treated with REMIFENTANIL, SEVOFLURANE. Patient recovered.
Propofol Side Effects Report #5239579-9
Propofol side effect was reported by a Physician from UNITED KINGDOM on Feb 05, 2007. Female patient, 21 years of age, was diagnosed with anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with SEVOFLURANE. Patient recovered.
Propofol Side Effects Report #4960811-0
Propofol side effect was reported by a Pharmacist from UNITED STATES on Mar 31, 2006. Female patient, 66 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: metabolic acidosis, pco2 decreased. Propofol dosage: unknown. Patient was hospitalized. Patient recovered.
Propofol Side Effects Report #4642303-1
Propofol side effect was reported by a Consumer or non-health professional from on Apr 11, 2005. Male patient, 40 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: anaesthetic complication, hyperkalaemia, metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with SUFENTANIL CITRATE, VERCURONIUM, MIDAZOLAM. Patient recovered.
Propofol Side Effects Report #4644656-7
Propofol side effect was reported by a Consumer or non-health professional from on Apr 11, 2005. Male patient, 40 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: anaesthetic complication, hyperkalaemia, metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with SUFENTANIL CITRATE, VERCURONIUM, MIDAZOLAM. Patient recovered.
Propofol Side Effects Report #4647155-1
Propofol side effect was reported by a Physician from on Apr 18, 2005. Male patient, 40 years of age, weighting 165.3 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, haemodialysis, hyperkalaemia, hyperthermia malignant, metabolic acidosis, metabolic disorder
, myopathy, pathogen resistance. Propofol dosage: unknown. During the same period patient was treated with VERCURONIUM, MIDAZOLAM, SUFENTANIL CITRATE. Patient recovered.Propofol Side Effects Report #5169054-1
Propofol side effect was reported by a Health Professional from POLAND on Dec 04, 2006. Female patient, child 4 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: hepatomegaly, hyperkalaemia, hypotension, international normalised ratio increased, lipids abnormal, metabolic acidosis, propofol infusion syndrome, rhabdomyolysis, tachycardia. Propofol dosage: unknown. Patient died.
Propofol Side Effects Report #5102523-9
Propofol side effect was reported by a Health Professional from JAPAN on Sept 06, 2006. Female patient, 32 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: haemoglobin decreased, hyponatraemia, metabolic acidosis, water intoxication. Propofol dosage: unknown. During the same period patient was treated with FENTANEST. Patient recovered.
Propofol Side Effects Report #4968016-4
Propofol side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 24, 2006. Female patient, 27 years of age, was diagnosed with blood pressure management, hypotension and was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest
, cardiac pacemaker malfunction, hyperkalaemia, hypotension, metabolic acidosis, propofol infusion syndrome. Propofol dosage: unknown. During the same period patient was treated with DOPAMINE, EPINEPHRINE. Patient died.Propofol Side Effects Report #4960734-7
Propofol side effect was reported by a Physician from UNITED STATES on Oct 18, 1993. Female patient, child 2 years of age, weighting 28.66 lb, was diagnosed with bronchitis chronic, sepsis
and was treated with Propofol. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiac failure, lipids abnormal, metabolic acidosis, sinus bradycardia. Propofol dosage: 10 MG/ML 4DYS. During the same period patient was treated with AMOXICILLIN, CEFOTAXIME, FLUCLOXACILLIN. Patient died.Propofol Side Effects Report #5455735-9
Propofol side effect was reported by a Physician from UNITED STATES on Sept 05, 2007. Male patient, 18 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: anuria, arrhythmia
, circulatory collapse, metabolic acidosis, propofol infusion syndrome, rhabdomyolysis. Propofol dosage: INC DOSE MAX OF 7.5 MG/KG/H, INFUSION. During the same period patient was treated with MORPHINE, VASOPRESSOR. Patient died.Propofol Side Effects Report #4580135-3
Propofol side effect was reported by a Consumer or non-health professional from on Feb 04, 2005. Male patient, 17 years of age, weighting 143.3 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest
, hyperkalaemia, hypotension, metabolic acidosis, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with MORPHINE HYDROCHLORIDE, MIDAZOLAM. Patient recovered.