Propofol and blood creatine phosphokinase increased Patient Reports February 11, 2012

Propofol Side Effects Report #5075609-5
Propofol side effect was reported by a Health Professional from UNITED KINGDOM on Aug 03, 2006. Male patient, 51 years of age, weighting 176.4 lb, was diagnosed with subdural haemorrhage, hypertension, blood cholesterol increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, myoglobinuria, renal failure, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with AMLODIPINE, ANADIN, ATORVASTATIN CALCIUM, RAMIPRIL, WARFARIN. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5113662-0
Propofol side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 21, 2006. Male patient, weighting 234.8 lb, was diagnosed with status epilepticus and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, cardiac arrest , metabolic acidosis, propofol infusion syndrome, ventricular tachycardia. Propofol dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, INSULIN, DEXAMETHASONE, LAMOTRIGINE, PENICILLIN G POTASSIUM, PHENOBARBITAL, PHENYTOIN, RANITIDINE. Patient died on 02/15/2006.

Propofol Side Effects Report #4689137-X
Propofol side effect was reported by a Physician from on May 31, 2005. Male patient, child 7 years of age, was diagnosed with sedation, anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, injury, lactic acidosis, procedural complication, rhabdomyolysis. Propofol dosage: TOTAL DOSE 6.1 MG/KG BW). During the same period patient was treated with THIOPENTAL, MIVACURIUM, FENTANYL, SEVOFLURANE. Patient recovered.

Propofol Side Effects Report #4816621-8
Propofol side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 31, 2005. Male patient, 49 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, cardiac arrest , circulatory collapse, haemodialysis, hepatic failure, lactic acidosis, mitochondrial toxicity, propofol infusion syndrome, renal failure. Propofol dosage: 2.4 MG/KG/HR. During the same period patient was treated with VASOPRESSIN, NOREPINEPHRINE, ZOSYN, VANCOMYCIN, CEFEPIME, DROTRECOGIN ALFA. Patient died on 05/12/2005.


Propofol Side Effects Report #5927934-0
Propofol side effect was reported by a Pharmacist from UNITED STATES on Oct 22, 2008. Male patient, 45 years of age, weighting 202.8 lb, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood triglycerides increased, bradycardia, cardiac arrest , propofol infusion syndrome, respiratory acidosis. Propofol dosage: 100 MG AS NEEDED IV. Patient recovered.

Propofol Side Effects Report #4659222-7
Propofol side effect was reported by a Health Professional from on May 03, 2005. Male patient, 36 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood urine present, chromaturia, myoglobinaemia. Propofol dosage: 2% PROPOFOL WITH 0.1G/ML FAT (12.5G DAILY OF FAT). During the same period patient was treated with DOPAMINE, FUROSEMIDE, AMPICILLIN, CLINDAMYCIN. Patient recovered.

Propofol Side Effects Report #5004138-X
Propofol side effect was reported by a Health Professional from BELGIUM on May 11, 2006. Male patient, 30 years of age, was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood lactic acid increased, propofol infusion syndrome, sinus arrhythmia, troponin t increased. Propofol dosage: unknown. During the same period patient was treated with REMIFENTANYL. Patient recovered.

Propofol Side Effects Report #5062819-6
Propofol side effect was reported by a Pharmacist from UNITED STATES on July 24, 2006. Male patient was diagnosed with sedation and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, bradycardia, electrocardiogram qt corrected interval prolonged. Propofol dosage: unknown. Patient recovered.

Propofol Side Effects Report #5788349-1
Propofol side effect was reported by a Health Professional from UNITED STATES on June 11, 2008. Female patient, 33 years of age, was diagnosed with intracranial pressure increased and was treated with Propofol. After drug was administered, patient experienced the following side effects: acute coronary syndrome, atrioventricular block first degree, blood creatine phosphokinase increased, blood triglycerides increased, bradycardia, bundle branch block left, bundle branch block right, cardiac arrest , convulsion. Propofol dosage: unknown. During the same period patient was treated with MORPHINE, NOREPINEPHRINE BITARTRATE, PANCURONIUM. Patient died.


Propofol Side Effects Report #5993326-1
Propofol side effect was reported by a Health Professional from UNITED STATES on Dec 10, 2008. Male patient, 25 years of age, was diagnosed with intracranial pressure increased, cerebral hypoperfusion, csf pressure and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, electrocardiogram t wave inversion, metabolic acidosis, propofol infusion syndrome. Propofol dosage: unknown. During the same period patient was treated with PHENYLEPHRINE, PENTOBARBITAL CAP, THIOPENTAL. Patient died.

Propofol Side Effects Report #5042691-0
Propofol side effect was reported by a Health Professional from JAPAN on May 31, 2006. Male patient, 22 years of age, was diagnosed with induction of anaesthesia, maintenance of anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood calcium increased, blood creatine phosphokinase increased, hepatic function abnormal, hyperthermia malignant, metabolic acidosis. Propofol dosage: unknown. During the same period patient was treated with SUXAMETHONIUM CHLORIDE, OXYGEN, SEVOFLURANE, FENTANYL CITRATE. Patient recovered.

Propofol Side Effects Report #5973267-6
Propofol side effect was reported by a Physician from UNITED STATES on Nov 11, 2008. Male patient, 64 years of age, was diagnosed with convulsion and was treated with Propofol. After drug was administered, patient experienced the following side effects: anoxic encephalopathy, blood creatine phosphokinase increased, blood triglycerides increased, hypotension, lactic acidosis, myoglobin blood increased, propofol infusion syndrome, renal failure acute. Propofol dosage: 1 MG/JG BOLUS, INFUSION OF 120-140 ?G/KG/MI. Patient was hospitalized. Patient died.

Propofol Side Effects Report #4694817-6
Propofol side effect was reported by a Physician from on June 06, 2005. Male patient, 42 years of age, weighting 169.8 lb, was diagnosed with anaesthesia and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, hypertension, lactic acidosis, myoglobinuria, procedural hypertension, propofol infusion syndrome, renal impairment, rhabdomyolysis. Propofol dosage: 5.2 MG KG^-1 H^-1. During the same period patient was treated with METHYLPREDNISOLONE, SEVOFLURANE, HETASTARCH IN CHLORIDE. Patient recovered.

Propofol Side Effects Report #5307274-3
Propofol side effect was reported by a Pharmacist from UNITED STATES on Apr 23, 2007. Male patient, 18 years of age, weighting 275.6 lb, was diagnosed with acute respiratory distress syndrome, treatment failure and was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, haemodialysis, oxygen saturation decreased, renal failure acute, rhabdomyolysis. Propofol dosage: 34,000 MG IN 4-5 DAYS ~ 3-5 MG/KG/HR. During the same period patient was treated with MIDAZOLAM DRIP, FENTANYL DRIP, REGLAN, NEXIUM. Patient was hospitalized. Patient recovered.


Propofol Side Effects Report #4587320-5
Propofol side effect was reported by a Consumer or non-health professional from on Feb 04, 2005. Male patient, child 9 years of age, weighting 88.18 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, hypercapnia, hyperkalaemia, pyrexia. Propofol dosage: 120 MG ONCE. During the same period patient was treated with FENTANYL, SUCCINYLCHOLINE CHLORIDE, SEVOFLURANE. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5450651-0
Propofol side effect was reported by a Physician from UNITED STATES on Aug 27, 2007. Male patient, 52 years of age, weighting 187.4 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, hyperthermia, post procedural complication, respiratory alkalosis. Propofol dosage: 200MG (2.2MG/KG) IV X 1. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #4647155-1
Propofol side effect was reported by a Physician from on Apr 18, 2005. Male patient, 40 years of age, weighting 165.3 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, haemodialysis, hyperkalaemia, hyperthermia malignant, metabolic acidosis, metabolic disorder , myopathy, pathogen resistance. Propofol dosage: unknown. During the same period patient was treated with VERCURONIUM, MIDAZOLAM, SUFENTANIL CITRATE. Patient recovered.

Propofol Side Effects Report #5067928-3
Propofol side effect was reported by a Health Professional from UNITED KINGDOM on July 21, 2006. Male patient, 29 years of age, was treated with Propofol. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood creatine phosphokinase increased, rhabdomyolysis. Propofol dosage: unknown. During the same period patient was treated with FENTANYL, SUCCINYLCHOLINE CHLORIDE, RABEPRAZOLE, INHALERS. Patient was hospitalized. Patient recovered.

Propofol Side Effects Report #5078628-8
Propofol side effect was reported by a Physician from UNITED STATES on Aug 09, 2006. Male patient, 27 years of age, weighting 241.0 lb, was treated with Propofol. After drug was administered, patient experienced the following side effects: agitation, atrial fibrillation , blood creatine phosphokinase increased, blood pressure increased, myoglobin blood increased, propofol infusion syndrome, tachycardia, troponin increased. Propofol dosage: unknown. Patient died on 04/02/2005.