Prograf and lymphoproliferative disorder Patient Reports February 10, 2012

Prograf Side Effects Report #5343630-5
Prograf side effect was reported by a Health Professional from AUSTRALIA on May 15, 2007. Male patient, 36 years of age, was diagnosed with transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: epstein-barr virus antibody positive, hepatic lesion, liver function test abnormal, lung neoplasm, lymphoproliferative disorder, non-hodgkin's lymphoma, ureteric stenosis. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #6062871-5
Prograf side effect was reported by a Health Professional from COLOMBIA on Jan 20, 2009. Male patient was diagnosed with transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: 2 MG, UID/QD, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL. Patient died on 12/20/2008.

Prograf Side Effects Report #5702059-8
Prograf side effect was reported by a Physician from JAPAN on Mar 28, 2008. Female patient, weighting 21.83 lb, was diagnosed with small intestine transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: cholangitis, coagulopathy, gastrointestinal necrosis, hepatic failure, hepatic steatosis, intestinal resection, lymphoproliferative disorder, pleural effusion, septic shock. Prograf dosage: unknown. During the same period patient was treated with STEROID, SIMULECT. Patient died on 11/16/2003.

Prograf Side Effects Report #5531785-9
Prograf side effect was reported by a Physician from UNITED STATES on Nov 12, 2007. Male patient, child 6 years of age, weighting 50.71 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder, respiratory rate increased, tonsillar hypertrophy. Prograf dosage: unknown. During the same period patient was treated with ZENAPAX. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #5626052-9
Prograf side effect was reported by a Consumer or non-health professional from JAPAN on Feb 08, 2008. Female patient, 56 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoma , lymphoproliferative disorder, malaise, pneumonia , renal cell carcinoma. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, METHYLPREDNISOLONE, SIMULECT. Patient died on 01/01/2006.

Prograf Side Effects Report #5630351-4
Prograf side effect was reported by a Consumer or non-health professional from JAPAN on Feb 15, 2008. Female patient, 56 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoma , lymphoproliferative disorder, malaise, pneumonia , renal cell carcinoma. Prograf dosage: 3 MG/DAY. During the same period patient was treated with CELLCEPT, METHYLPREDNISOLONE, SIMULECT, RITUXIMAB. Patient died on 05/09/2006.

Prograf Side Effects Report #5133456-X
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Male patient, 53 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder, peptic ulcer . Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #5535119-5
Prograf side effect was reported by a Physician from JAPAN on Nov 15, 2007. Female patient, 53 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorexia, blood calcium increased, diffuse large b-cell lymphoma, gamma-glutamyltransferase increased, lymphadenopathy, lymphoproliferative disorder, malaise, metastases to bone, metastases to liver. Prograf dosage: 3 MG, BID, ORAL. During the same period patient was treated with CELLCEPT, MEDROL, SIMULECT, CONIEL, ALOSITOLLET. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5551247-2
Prograf side effect was reported by a Physician from JAPAN on Nov 29, 2007. Female patient, 53 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorexia, blood calcium increased, diffuse large b-cell lymphoma, gamma-glutamyltransferase increased, lymphoproliferative disorder, malaise, metastases to bone, metastases to liver, pain . Prograf dosage: 3 MG, BID, ORAL. During the same period patient was treated with CELLCEPT, MEDROL, SIMULECT, CONIEL, ALOSITOL. Patient was hospitalized. Patient died.


Prograf Side Effects Report #5574137-8
Prograf side effect was reported by a Physician from JAPAN on Dec 07, 2007. Female patient, 53 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorexia, blood calcium increased, blood creatinine increased, diffuse large b-cell lymphoma, gamma-glutamyltransferase increased, lymphoproliferative disorder, malaise, metastases to bone, metastases to liver. Prograf dosage: 3 MG, BID, ORAL. During the same period patient was treated with CELLCEPT, MEDROL, SIMULECT, CONIEL, ALOSITOLLET. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5639194-9
Prograf side effect was reported by a Physician from JAPAN on Feb 08, 2008. Female patient, 53 years of age, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorexia, blood calcium increased, diffuse large b-cell lymphoma, gamma-glutamyltransferase increased, lymphoproliferative disorder, malaise, pain , pneumonia , renal impairment. Prograf dosage: 3 MG, BID, ORAL. During the same period patient was treated with CELLCEPT, MEDROL, SIMULECT, CONIEL, ALOSITOLLET. Patient was hospitalized. Patient died on 05/09/2006.

Prograf Side Effects Report #5103968-3
Prograf side effect was reported by a Physician from JAPAN on Aug 28, 2006. Male patient, 52 years of age, weighting 173.1 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, condition aggravated, epstein-barr virus infection, haemodialysis, immunosuppression, lymphoproliferative disorder, metastases to lung, pneumocystis jiroveci pneumonia, t-cell lymphoma. Prograf dosage: 2 MG, BID, ORAL; 3MG, D, ORAL. During the same period patient was treated with CELLCEPT, SIMULECT, MEDROL ACETATE, LANSOPRAZOLE, AMLODIPINE BESYLATE, URINORM, BLOPRESS. Patient died on 04/26/2006.

Prograf Side Effects Report #4835903-7
Prograf side effect was reported by a Physician from JAPAN on Nov 08, 2005. Female patient, 43 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , dialysis , epstein-barr virus infection, hydronephrosis, kidney transplant rejection, lymphoproliferative disorder, nephritis interstitial, renal hypertrophy. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE, BASILIXIMAB. Patient recovered.

Prograf Side Effects Report #4846634-1
Prograf side effect was reported by a Physician from JAPAN on Nov 21, 2005. Female patient, 43 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , graft dysfunction, haematuria, hydronephrosis, lymphoproliferative disorder, nephritis interstitial, renal hypertrophy. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE, BASILIXIMAB. Patient was hospitalized and became disabled. Patient recovered.


Prograf Side Effects Report #4835423-X
Prograf side effect was reported by a Physician from BELGIUM on Nov 07, 2005. Male patient, 40 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: b-cell lymphoma, cytomegalovirus infection , hepatic lesion, kidney fibrosis, lymphoproliferative disorder, polyomavirus-associated nephropathy, splenic lesion, viral infection . Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5133259-6
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Female patient, 38 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal ulcer, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5133257-2
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Male patient, 34 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal ulcer, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5541520-6
Prograf side effect was reported by a Physician from JAPAN on Nov 27, 2007. Male patient, 34 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: ascites, lymphoproliferative disorder, melaena, no therapeutic response, pancreatitis. Prograf dosage: unknown. During the same period patient was treated with IMURAN, PREDNISOLONE. Patient died on 06/08/2007.

Prograf Side Effects Report #5133258-4
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Male patient, 30 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal ulcer, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #5133256-0
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Male patient, 28 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal ulcer, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient recovered.

Prograf Side Effects Report #5133450-9
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Male patient, 22 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal ulcer, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5133260-2
Prograf side effect was reported by a Physician from JAPAN on Oct 03, 2006. Male patient, 19 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: gastrointestinal ulcer, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, METHYLPREDNISOLONE. Patient recovered.

Prograf Side Effects Report #5096718-0
Prograf side effect was reported by a Physician from JAPAN on Aug 21, 2006. Male patient, weighting 173.1 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, epstein-barr virus infection, haemodialysis, infection in an immunocompromised host, lymphoproliferative disorder, metastases to lung, pneumocystis jiroveci pneumonia, renal failure, t-cell lymphoma. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, SIMULECT, MEDROL ACETATE, LANSOPRAZOLE, AMLODIPINE BESYLATE, URINORM, BLOPRESS. Patient died on 04/01/2006.

Prograf Side Effects Report #5157760-4
Prograf side effect was reported by a Physician from JAPAN on Oct 30, 2006. Female patient, weighting 114.6 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood calcium increased, complications of transplanted kidney, gamma-glutamyltransferase increased, lymphadenopathy, lymphoma , lymphoproliferative disorder, metastases to bone, metastases to liver, renal impairment. Prograf dosage: 3 MG, BID, OAL. During the same period patient was treated with CELLCEPT, MEDROL, SIMULECT, CONIEL, ALLOPURINOL. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #4566566-6
Prograf side effect was reported by a Physician from on Jan 17, 2005. Male patient, 55 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, lymphoproliferative disorder. Prograf dosage: unknown. Patient died.

Prograf Side Effects Report #5200172-5
Prograf side effect was reported by a Physician from UNITED STATES on Dec 20, 2006. Female patient, 26 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , epistaxis, extranodal marginal zone b-cell lymphoma (malt type), loss of consciousness, lymphoproliferative disorder, normochromic normocytic anaemia, parvovirus b19 serology positive, weight decreased. Prograf dosage: unknown. During the same period patient was treated with PREDNISONE, CYCLOPORINE, GANCICLOVIR, EPOGEN, RITUXIMAB. Patient died.

Prograf Side Effects Report #4565410-0
Prograf side effect was reported by a Physician from on Jan 17, 2005. Male patient, 21 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, lymphoproliferative disorder, post procedural complication. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient died.

Prograf Side Effects Report #5036770-1
Prograf side effect was reported by a Health Professional from UNITED STATES on May 23, 2005. Female patient, 13 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: 2 MG, BID, ORAL. During the same period patient was treated with IMURAN, SINGULAIR, FLOVENT, PAXIL. Patient recovered.

Prograf Side Effects Report #5054125-0
Prograf side effect was reported by a Consumer or non-health professional from CHILE on June 28, 2006. Female patient was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: central nervous system lymphoma, epstein-barr virus antibody positive, lymphoproliferative disorder, non-hodgkin's lymphoma, sepsis . Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL. Patient died.


Prograf Side Effects Report #5026838-8
Prograf side effect was reported by a Physician from ISRAEL on May 28, 2006. Male patient, 63 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: lung transplant rejection, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL, TRIMETOPRIM. Patient died.

Prograf Side Effects Report #5466320-7
Prograf side effect was reported by a Health Professional from UNITED STATES on Sept 11, 2007. Male patient, 61 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: brain oedema, central nervous system lymphoma, convulsion, lymphoproliferative disorder, mental status changes, platelet count abnormal, post procedural haemorrhage. Prograf dosage: unknown. Patient died on 02/16/2006.

Prograf Side Effects Report #5503022-2
Prograf side effect was reported by a Health Professional from UNITED STATES on Oct 16, 2007. Male patient, 61 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: brain oedema, central nervous system lymphoma, convulsion, cytomegalovirus infection , lymphoproliferative disorder, platelet disorder, post procedural haemorrhage, transplant rejection. Prograf dosage: unknown. Patient died on 02/16/2006.

Prograf Side Effects Report #5026839-X
Prograf side effect was reported by a Physician from ISRAEL on May 28, 2006. Male patient, 49 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bladder cancer , colon cancer, kaposi's sarcoma , lung transplant rejection, lymphoproliferative disorder, neoplasm malignant, obliterative bronchiolitis, skin cancer , transitional cell carcinoma. Prograf dosage: unknown. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL, TRIMETOPRIM. Patient died.

Prograf Side Effects Report #5413442-2
Prograf side effect was reported by a Physician from JAPAN on July 27, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, interleukin level increased, lymphoproliferative disorder, no therapeutic response, osteomyelitis, pneumonia , respiratory disorder, transplant rejection. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #5467168-X
Prograf side effect was reported by a Physician from JAPAN on Sept 11, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, lung transplant rejection, lymphoproliferative disorder, osteomyelitis, pneumonia , pseudarthrosis, pyrexia, sternal fracture. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5504744-X
Prograf side effect was reported by a Physician from JAPAN on Oct 17, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, lymphoproliferative disorder, no therapeutic response, pneumonia , pseudarthrosis, staphylococcal osteomyelitis, sternal fracture, transplant rejection. Prograf dosage: 2 MG, BID,ORAL; 1.75 MGSEE IMAGE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5580096-4
Prograf side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, diarrhoea, eosinophil count increased, foreign body trauma, lymphoproliferative disorder, nausea , opportunistic infection. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5638756-2
Prograf side effect was reported by a Physician from JAPAN on Feb 06, 2008. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone graft , complications of transplanted lung, diarrhoea, iatrogenic injury, lung transplant rejection, lymphoproliferative disorder, nausea , no therapeutic response. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5580096-4
Prograf side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, diarrhoea, eosinophil count increased, lymphoproliferative disorder, opportunistic infection, osteomyelitis, pneumonia . Prograf dosage: unknown. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #5626161-4
Prograf side effect was reported by a Physician from FRANCE on Jan 23, 2008. Male patient, child 8 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, autoimmune thrombocytopenia, diarrhoea haemorrhagic, evans syndrome, lymphoproliferative disorder, marrow hyperplasia, therapeutic response decreased. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, IMMUNOGLOBULIN, CORTICOSTEROID NOS, RITUXIMAB. Patient recovered.

Prograf Side Effects Report #5646940-7
Prograf side effect was reported by a Physician from FRANCE on Feb 12, 2008. Male patient, child 8 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: diarrhoea haemorrhagic, erythema infectiosum, evans syndrome, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, IMMUNE GLOBULIN INTRAVENOUS, CORTICOSTEROID NOS, RITUXIMAB. Patient recovered.

Prograf Side Effects Report #5663652-4
Prograf side effect was reported by a Physician from FRANCE on Feb 15, 2008. Male patient, child 8 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: diarrhoea haemorrhagic, erythema infectiosum, evans syndrome, haemorrhage, lymphoproliferative disorder, marrow hyperplasia. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, IMMUNE GLOBULIN INTRAVENOUS, CORTICOSTEROID NOS, RITUXIMAB. Patient recovered.

Prograf Side Effects Report #5663893-6
Prograf side effect was reported by a Health Professional from FRANCE on Feb 15, 2008. Male patient, child 8 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: diarrhoea haemorrhagic, erythema infectiosum, evans syndrome, haemolytic anaemia, lymphoproliferative disorder, migraine , pancytopenia, parvovirus infection. Prograf dosage: 4.5 MG, BID, ORAL. During the same period patient was treated with CELLCEPT, ASPEGIC, CORTICOSTEROID NOS, IMMUNOGLOBULINS, RITUXIMAB. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5663894-8
Prograf side effect was reported by a Health Professional from FRANCE on Feb 15, 2008. Male patient, child 8 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: evans syndrome, lymphoproliferative disorder, no therapeutic response, pancytopenia, parvovirus infection. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, IMMUNOGLOBULINS, CORTICOSTEROID NOS, RITUXIMAB. Patient recovered.

Prograf Side Effects Report #5136401-6
Prograf side effect was reported by a Physician from UNITED KINGDOM on Oct 06, 2006. Male patient, 72 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: 0.2 MG, BID. During the same period patient was treated with MYCOPHENOLATE MOFETIL. Patient died.

Prograf Side Effects Report #5162071-7
Prograf side effect was reported by a Physician from UNITED KINGDOM on Nov 09, 2006. Male patient, 72 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: 0.5 MG, BID. During the same period patient was treated with MYCOPHENOLATE MOFETIL. Patient died on 01/01/2002.

Prograf Side Effects Report #5085453-0
Prograf side effect was reported by a Physician from ITALY on July 31, 2006. Female patient, 57 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of transplanted liver, disease progression, lung disorder, lymphadenopathy, lymphoproliferative disorder, nervous system disorder, post procedural complication, renal disorder. Prograf dosage: unknown. Patient died.

Prograf Side Effects Report #5136400-4
Prograf side effect was reported by a Physician from UNITED KINGDOM on Oct 06, 2006. Male patient, 50 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: 1 MG, BID. Patient died.

Prograf Side Effects Report #5160839-4
Prograf side effect was reported by a Physician from UNITED KINGDOM on Nov 09, 2006. Male patient, 50 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: 1 MG, BID. Patient died.


Prograf Side Effects Report #5713728-8
Prograf side effect was reported by a Physician from JAPAN on Apr 04, 2008. Male patient, child 4 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: autoimmune disorder, epstein-barr virus infection, graft versus host disease, idiopathic thrombocytopenic purpura, lymphoproliferative disorder, post procedural complication, varicella. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Prograf Side Effects Report #4750347-4
Prograf side effect was reported by a Physician from JAPAN on Aug 08, 2005. Male patient, 34 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: biliary dilatation, cytomegalovirus test positive, hepatic function abnormal, intestinal obstruction, large intestinal ulcer, lymphoproliferative disorder, melaena, multi-organ failure. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE. Patient recovered.

Prograf Side Effects Report #4757267-X
Prograf side effect was reported by a Physician from JAPAN on Aug 16, 2005. Male patient, 34 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: biliary dilatation, cytomegalovirus test positive, hepatic enzyme increased, hepatic function abnormal, intestinal obstruction, large intestinal ulcer, liver transplant rejection, lymphoproliferative disorder, melaena. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE. Patient was hospitalized. Patient died on 03/01/2005.

Prograf Side Effects Report #5487325-6
Prograf side effect was reported by a Health Professional from NEW ZEALAND on Sept 28, 2007. Female patient, child 3 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: burkitt's lymphoma, lymphoproliferative disorder. Prograf dosage: 1.25 MG, BID, ORAL. Patient died on 09/28/2007.

Prograf Side Effects Report #5671749-8
Prograf side effect was reported by a Physician from UNITED STATES on Mar 06, 2008. Male patient, 22 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: haemoptysis, lymphoproliferative disorder, pulmonary embolism , transplant rejection. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, PIPERACILLIN, TOBRAMYCIN, VANCOMYCIN HYDROCHLORIDE. Patient died.

Prograf Side Effects Report #5844409-8
Prograf side effect was reported by a Physician from JAPAN on July 29, 2008. Female patient, child 2 years of age, weighting 18.96 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: catheter site related reaction, dehydration, epstein-barr virus infection, implant site thrombosis, lymphoproliferative disorder, malnutrition, pleural effusion, pulmonary embolism . Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5009097-1
Prograf side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on May 08, 2006. Male patient, child 12 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, b-cell lymphoma, epstein-barr virus infection, gastric ulcer, hepatitis fulminant, lymphoproliferative disorder, melaena, metastasis, sepsis . Prograf dosage: unknown. During the same period patient was treated with METHYLPRDENISOLONE, PREDNISOLONE. Patient died.

Prograf Side Effects Report #4785892-9
Prograf side effect was reported by a Physician from JAPAN on Sept 22, 2005. Female patient, child 10 years of age, weighting 52.91 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: burkitt's lymphoma, cytomegalovirus infection , enterocolitis, epstein-barr virus infection, haemodialysis, lymphoproliferative disorder, multi-organ failure, pleurisy, renal failure. Prograf dosage: 1.00 MG, BID, ORAL. During the same period patient was treated with STEROIDECTION. Patient was hospitalized. Patient died on 03/02/2005.

Prograf Side Effects Report #4830944-8
Prograf side effect was reported by a Physician from JAPAN on Oct 31, 2005. Female patient, child 10 years of age, weighting 52.91 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: burkitt's lymphoma, cytomegalovirus infection , enterocolitis, epstein-barr virus infection, haemodialysis, liver disorder, lymphoproliferative disorder, multi-organ failure, pleurisy. Prograf dosage: 1.00 MG, TID, ORAL. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient died on 03/02/2005.

Prograf Side Effects Report #6083643-1
Prograf side effect was reported by a Physician from UNITED STATES on Feb 06, 2009. Female patient, 19 years of age, was diagnosed with intestinal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of intestinal transplant, lymphoproliferative disorder, mesenteric fibrosis. Prograf dosage: unknown. During the same period patient was treated with ANTITHYMOCYTE IMMUNOGLOBULIN. Patient recovered.


Prograf Side Effects Report #5193196-8
Prograf side effect was reported by a Physician from JAPAN on Dec 08, 2006. Male patient, child 6 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of bone marrow transplant, lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, CYCLOPHOSPHOMIDE, BUSULFAN, FLUDARA. Patient died.

Prograf Side Effects Report #5196475-3
Prograf side effect was reported by a Physician from JAPAN on Dec 15, 2006. Male patient, child 6 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, CYCLOPHOSPHAMIDE, PREDNISOLONE. Patient died on 07/04/2006.

Prograf Side Effects Report #4600817-4
Prograf side effect was reported by a Physician from on Feb 23, 2005. Female patient, 53 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, hepatitis acute, hepatitis infectious mononucleosis, infection in an immunocompromised host, lymphocyte morphology abnormal, lymphoproliferative disorder, multi-organ failure, pancytopenia. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient died on 04/03/2004.

Prograf Side Effects Report #5207327-4
Prograf side effect was reported by a Physician from JAPAN on Dec 27, 2006. Male patient, child 5 years of age, weighting 55.12 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenoidal hypertrophy, bacteraemia, catheter related infection, cyanosis, dysphonia, lymphoproliferative disorder, obstructive airways disorder, rhinorrhoea. Prograf dosage: 0.5 MG, UID/QD; IV DRIP. During the same period patient was treated with METHOTREXATEMULATION, CYCLOPHOSPHAMIDE, BUSULFAN, FLUDARA, MEDROL, FLUMARIN. Patient died on 07/04/2006.

Prograf Side Effects Report #5271823-4
Prograf side effect was reported by a Physician from JAPAN on Feb 28, 2007. Male patient, child 5 years of age, weighting 55.12 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: catheter related infection, gastrointestinal infection, lymphoproliferative disorder, staphylococcal sepsis. Prograf dosage: 0.5 MG, UID/QD, IV DRIP. During the same period patient was treated with METHOTREXATE, CYLOPHOSPHAMIDE, BUSULFAN, FLUDARA, MEDROL, FLUMARIN. Patient died on 07/04/2006.

Prograf Side Effects Report #5348442-4
Prograf side effect was reported by a Physician from JAPAN on May 25, 2007. Male patient, child 5 years of age, weighting 55.12 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, catheter related infection, cyanosis, gastrointestinal infection, lymphoproliferative disorder, obstructive airways disorder, pancytopenia, sepsis . Prograf dosage: 0.5 MG, UID/QD, IV DRIP. During the same period patient was treated with MEDROL, FLUMARIN. Patient died on 07/04/2006.

Prograf Side Effects Report #5196481-9
Prograf side effect was reported by a Physician from JAPAN on Dec 15, 2006. Male patient, child 5 years of age, weighting 55.12 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bacteraemia, lymphoproliferative disorder, sepsis . Prograf dosage: 0.5 + 0.2 MG, UID/QD, IV DRIP - SEE IMAGE. During the same period patient was treated with METHOTREXATEMULATION, CYCLOPHOSPHAMIDE, BUSUFAN, MEDROL, FLUMARIN. Patient died on 07/04/2006.

Prograf Side Effects Report #4877542-8
Prograf side effect was reported by a Physician from JAPAN on Dec 26, 2005. Female patient, 31 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cytomegalovirus viraemia, hyperbilirubinaemia, hypercholesterolaemia, hypertriglyceridaemia, lymphoproliferative disorder, obliterative bronchiolitis, pneumatosis intestinalis, pneumomediastinum, tremor. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4877537-4
Prograf side effect was reported by a Physician from JAPAN on Dec 27, 2005. Female patient, child 11 years of age, weighting 89.95 lb, was diagnosed with bone marrow transplant , chronic myeloid leukaemia and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of transplant surgery, convulsion, epstein-barr virus infection, herpes zoster, hypertension, lymphoproliferative disorder, rash , reversible posterior leukoencephalopathy syndrome, scab . Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, FLUDARABINE PHOSPHATE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5164830-3
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2006. Male patient, 65 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: b-cell lymphoma, catheter related complication, hepatic neoplasm, lymphoproliferative disorder, renal failure acute, tumour lysis syndrome, urate nephropathy, venous thrombosis, ventricular dysfunction. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, PREDNISONE. Patient died.


Prograf Side Effects Report #5196487-X
Prograf side effect was reported by a Health Professional from AUSTRALIA on Dec 12, 2006. Male patient, 36 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: hepatic lesion, lung neoplasm, lymphoproliferative disorder, non-hodgkin's lymphoma, ureteric stenosis. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.