Prograf and depressed level of consciousness Patient Reports February 11, 2012

Prograf Side Effects Report #5160822-9
Prograf side effect was reported by a Health Professional from AUSTRALIA on Nov 07, 2006. Male patient, 63 years of age, was diagnosed with transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, encephalopathy, post procedural complication. Prograf dosage: 2 MG,. During the same period patient was treated with PROPOFOL, FENTANYL, METARAMINOL TARTRATE, ALFENTANIL HYDROCHLORIDE, CISATRACURIUM BESILATE, METOPROLOL TARTRATE, FLECAINIDE ACETATE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5305462-3
Prograf side effect was reported by a Physician from JAPAN on Mar 29, 2007. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, graft versus host disease, hepatic failure, human herpesvirus 6 infection, liver disorder. Prograf dosage: unknown. During the same period patient was treated with ACYCLOVIR. Patient died.

Prograf Side Effects Report #5319718-1
Prograf side effect was reported by a Physician from JAPAN on Apr 16, 2007. Male patient, 58 years of age, weighting 159.8 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, bone marrow transplant , bronchopulmonary aspergillosis, depressed level of consciousness, hepatic failure, human herpesvirus 6 infection, oral candidiasis. Prograf dosage: unknown. During the same period patient was treated with ACYCLOVIR, TEICOPLANINECTION, MILLISROL, NOVOLIN R, FUNGUARD, FLUDARA, ALKERAN. Patient died on 01/06/2005.

Prograf Side Effects Report #5319748-X
Prograf side effect was reported by a Physician from JAPAN on Apr 16, 2007. Male patient, 58 years of age, weighting 159.8 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in liver, bronchopulmonary aspergillosis, depressed level of consciousness, hepatic failure, human herpesvirus 6 infection, liver disorder, oral candidiasis. Prograf dosage: unknown. During the same period patient was treated with ACYCLOVIR, TEICOPLANINECTION, MILLISROL, NOVOLIN R, FLUDARA, ALKERAN. Patient died on 01/06/2005.


Prograf Side Effects Report #5848386-5
Prograf side effect was reported by a Physician from JAPAN on Aug 05, 2008. Male patient, 42 years of age, weighting 142.2 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, bone marrow failure, bronchopulmonary aspergillosis, depressed level of consciousness, heart rate increased, histiocytosis haematophagic, sepsis . Prograf dosage: 3.0 MG, CONTINUOUS, IV DRIP. During the same period patient was treated with CELLCEPT, PREDNISOLONE. Patient was hospitalized. Patient died on 11/11/2007.

Prograf Side Effects Report #5897818-5
Prograf side effect was reported by a Physician from JAPAN on Sept 19, 2008. Male patient, 42 years of age, weighting 142.2 lb, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, bone marrow failure, bronchopulmonary aspergillosis, depressed level of consciousness, diarrhoea, disease progression, graft versus host disease, heart rate increased, histiocytosis haematophagic. Prograf dosage: 3 MG, CONTINUOUS, IV DRIP. During the same period patient was treated with CELLCEPT, PREDNISOLONE. Patient died on 11/11/2007.

Prograf Side Effects Report #5451901-7
Prograf side effect was reported by a Physician from JAPAN on Aug 30, 2007. Female patient, 65 years of age, weighting 43.30 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anxiety , autoimmune thrombocytopenia, cardiac arrest , condition aggravated, depressed level of consciousness, diarrhoea, haematochezia, headache . Prograf dosage: 1 MG, UID/QD, ORAL. During the same period patient was treated with ENBREL, PREDONINE, ARAVA, AMLODIN, LIPITOR, TAKEPRON, ARTIST. Patient was hospitalized. Patient died on 08/09/2007.

Prograf Side Effects Report #5467424-5
Prograf side effect was reported by a Physician from JAPAN on Sept 11, 2007. Female patient, 65 years of age, weighting 95.46 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, anxiety , autoimmune thrombocytopenia, condition aggravated, depressed level of consciousness, diarrhoea, fatigue, haematochezia. Prograf dosage: 1 MG, UID/QD, ORAL. During the same period patient was treated with ENBREL, PREDNISOLONE, ARAVA, AMLODIPINE BESYLATE, LIPITOR, LANSOPRAZOLE, ARTSIT. Patient was hospitalized. Patient died on 08/09/2007.

Prograf Side Effects Report #4766249-3
Prograf side effect was reported by a Health Professional from FRANCE on Sept 01, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, diarrhoea, diarrhoea infectious, effusion, gastrointestinal inflammation, haemolytic anaemia, hepatitis , hepatitis cholestatic, histiocytosis haematophagic. Prograf dosage: unknown. During the same period patient was treated with NEORAL, CELLCEPT, ARANESP, TARDYFERON, FORTUM, FUROSEMIDE, EPREX, ALLOPURINOL. Patient was hospitalized. Patient died on 06/02/2005.


Prograf Side Effects Report #4822714-1
Prograf side effect was reported by a Health Professional from FRANCE on Oct 21, 2005. Male patient, 58 years of age, was diagnosed with renal transplant, renal failure chronic and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, diarrhoea, gastrointestinal haemorrhage, hepatitis cholestatic, histiocytosis haematophagic, hypertriglyceridaemia, hypoglobulinaemia, infection . Prograf dosage: 0.50 MG, UID/QD,. During the same period patient was treated with NEORAL, CELLCEPT, ARANESP, TARDYFERON, FORTUM, FUROSEMIDE, EPREX, ZYLORIC. Patient was hospitalized. Patient died on 06/02/2005.

Prograf Side Effects Report #5633649-9
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 08, 2008. Female patient, 47 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: atrial fibrillation , cholelithiasis, depressed level of consciousness, depressed mood, gastrointestinal haemorrhage, hypoglycaemia, osteomyelitis, renal failure acute, respiratory arrest. Prograf dosage: unknown. Patient was hospitalized. Patient died on 12/06/2007.

Prograf Side Effects Report #5678863-1
Prograf side effect was reported by a Physician from UNITED STATES on Mar 11, 2008. Female patient, 47 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: asthenia, atrial fibrillation , brain injury, cholelithiasis, depressed level of consciousness, depressed mood, depression , dialysis , gastrointestinal haemorrhage. Prograf dosage: 0.5 MG, BID. Patient was hospitalized. Patient died on 12/06/2007.

Prograf Side Effects Report #5729860-9
Prograf side effect was reported by a Physician from UNITED STATES on Apr 25, 2008. Female patient, 47 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, asthenia, atrial fibrillation , brain injury, cholelithiasis, depressed level of consciousness, depressed mood, dialysis , electroencephalogram abnormal. Prograf dosage: 0.5 MG, BID. Patient was hospitalized. Patient died on 12/06/2007.

Prograf Side Effects Report #6115934-X
Prograf side effect was reported by a Physician from JAPAN on Mar 06, 2009. Female patient, 39 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal distension, anaemia, blood lactate dehydrogenase increased, cardiovascular disorder, depressed level of consciousness, disseminated intravascular coagulation, gastrointestinal haemorrhage, hepatic function abnormal. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient died on 05/03/2008.


Prograf Side Effects Report #4818554-X
Prograf side effect was reported by a Health Professional from FRANCE on Oct 20, 2005. Female patient, 32 years of age, weighting 141.1 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: brain scan abnormal, convulsion, depressed level of consciousness, electroencephalogram abnormal, hemiplegia, ischaemic stroke, leukoencephalopathy. Prograf dosage: 0.15 MG/KG,UID/QD,ORAL ; 0.10 MG/KG, UID/QD, ORAL. During the same period patient was treated with FUROSEMIDE, PREDNISONE, SIMULECT, VANCOMYCIN. Patient died on 03/27/2004.

Prograf Side Effects Report #4558910-0
Prograf side effect was reported by a Physician from on Jan 10, 2005. Male patient, 59 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: bk virus infection, coronary artery disease , depressed level of consciousness, gastric ulcer perforation, herpes oesophagitis, hydronephrosis, hypoxia, nephropathy, peritonitis. Prograf dosage: unknown. During the same period patient was treated with AZATHIOPRINE, PREDNISONE. Patient died.

Prograf Side Effects Report #4660779-0
Prograf side effect was reported by a Consumer or non-health professional from on May 05, 2005. Female patient, 59 years of age, weighting 135.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorexia, deep vein thrombosis , depressed level of consciousness, hyperglycaemia, international normalised ratio increased, post procedural complication, pulmonary embolism , spinal osteoarthritis, ventricular hypertrophy. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, PREDNISONE, ATENOLOL, NORVASC, CLONIDINE, ISOPHANE INSULIN. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4779542-5
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 09, 2005. Female patient, 59 years of age, weighting 135.4 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, chest pain , deep vein thrombosis , depressed level of consciousness, dyspnoea, dyspnoea exertional, haemodynamic instability, hyperglycaemia. Prograf dosage: 4 MG 2X PER 1 DAY, NASOGASTRIC; VARYING DOSE FROM 3 MG DAILY TO 3 MG BID, NASOGASTRIC; 4 MG 2X PER 1. During the same period patient was treated with CELLCEPT, PREDNISONE, ZENAPAX, ATENOLOL, NORVASC, CLONIDINE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4547088-5
Prograf side effect was reported by a Physician from on Dec 23, 2004. Male patient, 50 years of age, weighting 101.0 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, cytomegalovirus infection , depressed level of consciousness, haematemesis, idiopathic thrombocytopenic purpura, pancreatitis, petechiae, thrombocytopenia. Prograf dosage: 4.00 MG, BID, ORAL. During the same period patient was treated with PREDNISONE, CELLCEPT, TRIMETOPRIM, METOPROLOL, ATORVASTATIN, ASPIRIN. Patient died on 12/17/2004.


Prograf Side Effects Report #4951435-X
Prograf side effect was reported by a Pharmacist from UNITED STATES on Mar 10, 2006. Male patient, 20 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenovirus infection, cardiac failure, depressed level of consciousness, hepatic failure, multi-organ failure, pancytopenia, respiratory failure, thrombotic thrombocytopenic purpura. Prograf dosage: 3MG, BID; ORAL. During the same period patient was treated with RANITIDINE, PENTAMIDINE, ITRACONZOLE, VALGANCICLOVIR. Patient died.

Prograf Side Effects Report #5284937-X
Prograf side effect was reported by a Physician from JAPAN on Mar 13, 2007. Female patient, 81 years of age, weighting 95.68 lb, was diagnosed with myasthenia gravis and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, immune system disorder, meningitis cryptococcal, oral candidiasis. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5705561-8
Prograf side effect was reported by a Physician from JAPAN on Apr 02, 2008. Female patient, 22 years of age, weighting 100.3 lb, was diagnosed with lupus nephritis and was treated with Prograf. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness, neuropsychiatric lupus. Prograf dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, TAKEPRON, BAYASPIRIN PER ORAL NOS, ONEALFA, BONALON, LOXOPROFEN, LENDORMIN, ADALAT LLET. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5081959-9
Prograf side effect was reported by a Physician from JAPAN on July 26, 2006. Male patient, 58 years of age, weighting 119.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase decreased, brain oedema, condition aggravated, depressed level of consciousness, haematoma, haemolytic anaemia, hepatic function abnormal, leukoencephalopathy, multi-organ failure. Prograf dosage: unknown. During the same period patient was treated with NEORAL, SANDIMMUNE. Patient died on 02/04/2006.

Prograf Side Effects Report #5906845-0
Prograf side effect was reported by a Health Professional from UNITED STATES on June 12, 2008. Female patient, 40 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, disease complication, fungal abscess central nervous system, infection , neurological symptom, post procedural haematoma. Prograf dosage: 5 MG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISOLONE ACETATE. Patient died on 01/01/1998.


Prograf Side Effects Report #5201746-8
Prograf side effect was reported by a Physician from JAPAN on Dec 20, 2006. Female patient, 24 years of age, weighting 89.07 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: chylothorax, convulsion, cytomegalovirus viraemia, depressed level of consciousness, enterocolitis, hyperglycaemia, lymphangioleiomyomatosis, lymphatic duct rupture, pleural effusion. Prograf dosage: unknown. During the same period patient was treated with IMURAN. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5228421-8
Prograf side effect was reported by a Physician from JAPAN on Jan 15, 2007. Female patient, 24 years of age, weighting 89.07 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: chylothorax, convulsion, cytomegalovirus viraemia, depressed level of consciousness, enterocolitis, hyperglycaemia, lymphatic duct rupture, pleural effusion, pneumonia staphylococcal. Prograf dosage: SEE IMGAE. During the same period patient was treated with IMURAN. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5261439-8
Prograf side effect was reported by a Physician from JAPAN on Feb 21, 2007. Female patient, 24 years of age, weighting 89.07 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: chylothorax, convulsion, cytomegalovirus viraemia, depressed level of consciousness, enterocolitis, hyperglycaemia, lymphatic duct rupture, pleural effusion, pneumonia staphylococcal. Prograf dosage: unknown. During the same period patient was treated with IMURAN. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4954496-7
Prograf side effect was reported by a Physician from JAPAN on Mar 09, 2006. Female patient, 24 years of age, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: complications of transplanted lung, convulsion, cytomegalovirus viraemia, depressed level of consciousness, hyperglycaemia, lymphangioleiomyomatosis, lymphatic duct rupture, pleural effusion, pneumonia staphylococcal. Prograf dosage: unknown. During the same period patient was treated with IMURAN. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4559098-2
Prograf side effect was reported by a Physician from on Jan 11, 2005. Male patient, child 6 years of age, weighting 64.15 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: affect lability, amnesia, attention deficit/hyperactivity disorder, convulsion, depressed level of consciousness, diarrhoea, encephalopathy, hypometabolism. Prograf dosage: unknown. During the same period patient was treated with ZOVIRAX, BACTRAMIN, CELLCEPT, BIOFERMIN R. Patient recovered.


Prograf Side Effects Report #4749920-9
Prograf side effect was reported by a Consumer or non-health professional from JAPAN on Aug 04, 2005. Male patient, 58 years of age, weighting 158.7 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, dyskinesia, leukoencephalopathy, neurosis. Prograf dosage: unknown. During the same period patient was treated with DIFLUCAN, BAKTAR, VALTREX, URSODIOL, LANSOPRAZOLE, HEPSERA, ZEFFIX. Patient recovered.

Prograf Side Effects Report #5026934-5
Prograf side effect was reported by a Physician from JAPAN on May 26, 2006. Male patient, 56 years of age, weighting 134.5 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: beta 2 microglobulin increased, blood bilirubin increased, blood lactate dehydrogenase increased, cardiac arrest , cardiac tamponade, depressed level of consciousness, histiocytosis haematophagic, pancytopenia, respiratory arrest. Prograf dosage: 8 MG,. During the same period patient was treated with MEDROL ACETATE, PENTICILLIN, FLUMARIN, FUNGUARD, EPOGIN, HABEKACIN, CEFTAZIDIME. Patient died on 09/11/2004.

Prograf Side Effects Report #5044270-8
Prograf side effect was reported by a Physician from JAPAN on June 20, 2006. Male patient, 56 years of age, weighting 134.5 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: beta 2 microglobulin increased, blood bilirubin increased, blood lactate dehydrogenase increased, cardiac arrest , cardiac tamponade, depressed level of consciousness, dialysis , haematoma, histiocytosis haematophagic. Prograf dosage: unknown. During the same period patient was treated with MEDROL ACETATE, PIPERACILLIN, FLUMARIN, FUNGUARD, EPOGEN, HABEKACIN. Patient died on 09/11/2004.

Prograf Side Effects Report #5072917-9
Prograf side effect was reported by a Physician from JAPAN on July 21, 2006. Female patient, 51 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: arterial rupture, cerebral arteritis, cerebrovascular disorder, cerebrovascular stenosis, convulsion, depressed level of consciousness, haemorrhagic cerebral infarction, thalamic infarction. Prograf dosage: 3 MG, CONTINUOUS, IV DRIP. During the same period patient was treated with SOL MEDROL, MEDROL ACETATE, TAKEPRON, LASIX, SULPERASON, STRONG NEO MINOPHAGEN C, VENOGLOBULIN. Patient recovered.

Prograf Side Effects Report #4635529-4
Prograf side effect was reported by a Health Professional from on Apr 01, 2005. Male patient, 51 years of age, was diagnosed with liver transplant , nocardiosis and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, aspergillosis, bone marrow depression, candida sepsis, cardiotoxicity, congestive cardiomyopathy, cytomegalovirus antibody positive, depressed level of consciousness. Prograf dosage: unknown. During the same period patient was treated with PREDNISONE, ROCEPHIN. Patient was hospitalized. Patient died on 03/04/2005.


Prograf Side Effects Report #5073037-X
Prograf side effect was reported by a Physician from JAPAN on July 21, 2006. Male patient, 44 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: brain stem syndrome, condition aggravated, depressed level of consciousness, hepatitis c , meningitis bacterial, mucormycosis, respiratory disorder. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient died on 10/18/2005.

Prograf Side Effects Report #4900728-0
Prograf side effect was reported by a Physician from JAPAN on Jan 24, 2006. Male patient, 34 years of age, weighting 207.9 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acidosis, cardiac arrest , complications of transplanted liver, depressed level of consciousness, haemodialysis, hepatic artery occlusion, liver transplant rejection, pancytopenia, renal failure. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, PREDNISOLONE, SPANIDIN, VALIXA, BAKTAR, URSO, PARIET. Patient died on 01/17/2006.

Prograf Side Effects Report #4932373-5
Prograf side effect was reported by a Physician from JAPAN on Feb 17, 2006. Male patient, 34 years of age, weighting 207.9 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acidosis, blood lactate dehydrogenase increased, cardiac arrest , complications of transplanted liver, depressed level of consciousness, hepatic artery occlusion, liver transplant rejection, pancytopenia, renal failure. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, PREDNISOLONE, SPANIDIN, VALIXA, BAKTAR, URSO, PARIET. Patient died on 01/17/2006.

Prograf Side Effects Report #4952161-3
Prograf side effect was reported by a Physician from AUSTRALIA on Mar 02, 2006. Male patient, child 1 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: agitation, blood potassium increased, cardiac arrest , cardiac murmur, complications of transplanted liver, cyanosis, depressed level of consciousness, hypoglycaemia. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, AZATHIOPRINE. Patient recovered.

Prograf Side Effects Report #5246204-X
Prograf side effect was reported by a Physician from JAPAN on Feb 07, 2007. Female patient, 33 years of age, was diagnosed with corneal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness. Prograf dosage: 6 MG, D, ORAL; 5 MG, D, ORAL. During the same period patient was treated with ZOLPIDEM TARTRATE, LEXOTAN, ALPRAZOLAM, FLUVOXAMINE MALEATE, TRAZODONE, DORAL, LEVOTHYROXINE, RINDERON. Patient recovered.


Prograf Side Effects Report #5255173-8
Prograf side effect was reported by a Physician from JAPAN on Feb 16, 2007. Female patient, 33 years of age, weighting 114.0 lb, was diagnosed with corneal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, RINDERONLET, THYRADIN S, LEXOTAN, ALPRAZOLAM, DEPROMEL, ZOLPIDEM TARTRATE, RESLIN. Patient recovered.

Prograf Side Effects Report #5270299-0
Prograf side effect was reported by a Physician from JAPAN on Feb 26, 2007. Female patient, 33 years of age, weighting 114.0 lb, was diagnosed with corneal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: conversion disorder, convulsion, depressed level of consciousness. Prograf dosage: 3 MG, BID, ORAL, 1.5 MG, BID, ORAL, 2 MG, BID,ORAL. During the same period patient was treated with CELLCEPT, RINDERONLET, THYRADIN S, LEXOTAN, ALPRAZOLAM, DEPROMEL. Patient recovered.

Prograf Side Effects Report #5050415-6
Prograf side effect was reported by a Physician from JAPAN on June 27, 2006. Female patient, child 9 years of age, weighting 85.98 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blepharospasm, convulsion, depressed level of consciousness, dyspnoea, encephalopathy, eye movement disorder, feeling abnormal, hearing impaired, memory impairment. Prograf dosage: 1 MG, D, IV DRIP. During the same period patient was treated with FUNGUARD, VICCLOX, MAXIPIME, FRAGMIN, DOPAMINE HYDROCHLORIDE, URSO, ITRACONAZOLE. Patient was hospitalized and became disabled. Patient recovered.

Prograf Side Effects Report #4950103-8
Prograf side effect was reported by a Physician from JAPAN on Mar 07, 2006. Female patient, child 9 years of age, weighting 85.98 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: cardiac failure, convulsion, depressed level of consciousness, disseminated intravascular coagulation, encephalopathy, engraftment syndrome, enterocolitis, eye movement disorder, feeling abnormal. Prograf dosage: 1 MG, IV DRIP. During the same period patient was treated with FUNGUARD, VICCLOX, MAXIPIME, FRAGMIN, INOVAN, URSO, ITRIZOLE. Patient was hospitalized and became disabled. Patient recovered.

Prograf Side Effects Report #5030143-3
Prograf side effect was reported by a Physician from JAPAN on June 02, 2006. Female patient, 61 years of age, weighting 98.33 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depressed level of consciousness, diarrhoea, disorientation, encephalitis herpes, graft versus host disease, liver disorder, memory impairment. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, PREDONINE, METHOTREXATE, ALLOPURINOL. Patient died on 10/12/2004.

Prograf Side Effects Report #5047215-X
Prograf side effect was reported by a Physician from JAPAN on June 13, 2006. Female patient, 52 years of age, weighting 92.59 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, engraftment syndrome, haemorrhagic cerebral infarction, infection in an immunocompromised host, renal failure, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with ZOVIRAX, GASTER DLET, MUCOSTA, URSO, FUNGUARD, VANCOMYCIN, MEROPEN, NEUPOGEN. Patient died on 04/10/2004.

Prograf Side Effects Report #4690164-7
Prograf side effect was reported by a Physician from on June 03, 2005. Female patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenovirus infection, cytomegalovirus antigen positive, depressed level of consciousness, epstein-barr virus infection, graft versus host disease, hepatitis fulminant, steroid withdrawal syndrome. Prograf dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, GANCICLOVIR, CYCLOSPORINE. Patient died on 01/01/2004.

Prograf Side Effects Report #4709346-0
Prograf side effect was reported by a Physician from JAPAN on June 23, 2005. Female patient, 51 years of age, weighting 143.3 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain , adenoviral hepatitis, blood pressure decreased, coagulopathy, condition aggravated, depressed level of consciousness, epstein-barr virus test positive, graft versus host disease, haemodialysis. Prograf dosage: 0.80 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, DENOSINE, DIFLUCAN, BAKTAR, GRAN, FUNGUARD, ZOVIRAX, ITRIZOLE. Patient died on 09/07/2004.

Prograf Side Effects Report #4719352-8
Prograf side effect was reported by a Physician from JAPAN on July 08, 2005. Female patient, 51 years of age, weighting 143.3 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain , adenovirus infection, coagulopathy, depressed level of consciousness, epstein-barr virus infection, haemodialysis, hepatic failure, hepatic necrosis, hepatitis fulminant. Prograf dosage: 0.80 MG BID ORAL. During the same period patient was treated with PREDNISONE, DENOSINE, DIFLUCAN, BAKTAR, GRAN, FUNGUARD, ZOVIRAX, ITRACONAZOLE. Patient died on 09/07/2004.

Prograf Side Effects Report #4941579-0
Prograf side effect was reported by a Physician from JAPAN on Feb 27, 2006. Male patient, 51 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: asthenia, cellulitis , cerebral infarction, cytomegalovirus viraemia, depressed level of consciousness, graft versus host disease, headache , mucormycosis. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATEMULATION, METHYLPREDNISOLONE. Patient died on 02/01/2005.


Prograf Side Effects Report #4951202-7
Prograf side effect was reported by a Physician from JAPAN on Mar 02, 2006. Female patient, 50 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5030520-0
Prograf side effect was reported by a Physician from JAPAN on June 05, 2006. Male patient, 43 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, graft versus host disease, pneumonia cytomegaloviral, respiratory failure, toxic induced encephalopathy. Prograf dosage: 2 MG, CONTINUOUS, IV DRIP; SEE IMAGE. During the same period patient was treated with METHOTREXATE, ENDOXAN, NEUPOGEN, TIENAM, DECADRON. Patient died on 10/09/2005.

Prograf Side Effects Report #5015898-6
Prograf side effect was reported by a Physician from JAPAN on May 10, 2006. Female patient, 42 years of age, weighting 112.4 lb, was diagnosed with bone marrow transplant , graft versus host disease and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, encephalitis herpes, graft versus host disease, hepatic failure, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHOTREXATE. Patient died on 06/18/2002.

Prograf Side Effects Report #5096719-2
Prograf side effect was reported by a Physician from JAPAN on Aug 22, 2006. Male patient, 35 years of age, weighting 110.2 lb, was diagnosed with bone marrow transplant , cytomegalovirus antigen positive and was treated with Prograf. After drug was administered, patient experienced the following side effects: adenoviral haemorrhagic cystitis, convulsion, cytomegalovirus viraemia, delirium, depressed level of consciousness, diarrhoea, gastric ulcer, graft versus host disease, hypoglycaemia. Prograf dosage: unknown. During the same period patient was treated with ARASENA A, ARASENA A, DENOSINE. Patient died on 05/19/2006.

Prograf Side Effects Report #4551225-6
Prograf side effect was reported by a Physician from on Dec 22, 2004. Female patient, 35 years of age, weighting 103.6 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, disorientation, encephalopathy, memory impairment, nervous system disorder, psychiatric symptom, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, MORPHINE. Patient recovered.

Prograf Side Effects Report #4855996-0
Prograf side effect was reported by a Physician from JAPAN on Dec 06, 2005. Male patient, 13 years of age, was diagnosed with bone marrow transplant , bronchopulmonary aspergillosis and was treated with Prograf. After drug was administered, patient experienced the following side effects: aspergillosis, brain abscess, brain oedema, depressed level of consciousness, dysarthria, dysphagia, graft versus host disease, hepatic enzyme increased. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD, STEROID. Patient died on 01/01/2005.

Prograf Side Effects Report #4868764-0
Prograf side effect was reported by a Physician from JAPAN on Dec 08, 2005. Male patient, 13 years of age, was diagnosed with bone marrow transplant , bronchopulmonary aspergillosis and was treated with Prograf. After drug was administered, patient experienced the following side effects: brain abscess, brain oedema, bronchopulmonary aspergillosis, depressed level of consciousness, nervous system disorder, speech disorder, staphylococcal infection , thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD, STEROID. Patient died on 01/01/2005.

Prograf Side Effects Report #4551230-X
Prograf side effect was reported by a Physician from on Dec 24, 2004. Female patient, child 10 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anuria, blood pressure decreased, bone marrow depression, cytomegalovirus infection , depressed level of consciousness, graft versus host disease, renal failure. Prograf dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, PREDNISOLONE. Patient died on 09/17/2004.

Prograf Side Effects Report #4577918-2
Prograf side effect was reported by a Physician from on Jan 25, 2005. Female patient, child 10 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anuria, blood pressure decreased, bone marrow depression, cytomegalovirus infection , depressed level of consciousness, graft versus host disease, haemodialysis, pyrexia. Prograf dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, PREDNISOLONE. Patient died on 09/17/2004.

Prograf Side Effects Report #5096720-9
Prograf side effect was reported by a Physician from JAPAN on Aug 23, 2006. Female patient was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness, hyperglycaemia, respiratory disorder. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD. Patient recovered.


Prograf Side Effects Report #5124462-X
Prograf side effect was reported by a Physician from JAPAN on Sept 22, 2006. Female patient was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: bone marrow transplant , convulsion, depressed level of consciousness, hyperglycaemia, respiratory disorder, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with FUNGUARD. Patient died on 09/11/2006.

Prograf Side Effects Report #5150792-1
Prograf side effect was reported by a Physician from JAPAN on Oct 31, 2006. Male patient, weighting 176.4 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, disorientation, encephalitis cytomegalovirus, encephalitis viral, encephalopathy, hepatic function abnormal, immunosuppression, nuclear magnetic resonance imaging abnormal, pain . Prograf dosage: 2 MG, BID, ORAL. During the same period patient was treated with PREDNONINE, CELLCEPT, SULFAMETHOXAZOLE, POLYGLOBIN, FIRSTCIN, FUNGUARD, NEUPOGEN, NEO MINOPHAGEN C. Patient was hospitalized. Patient died on 09/22/2005.

Prograf Side Effects Report #4812149-X
Prograf side effect was reported by a Physician from JAPAN on Oct 14, 2005. Male patient, weighting 20.50 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood stem cell transplant failure, culture throat positive, depressed level of consciousness, enterobacter infection, haemodialysis, intraventricular haemorrhage, multi-organ failure, pseudomonas infection, renal failure. Prograf dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, ALKERAN, PREDNISOLONE. Patient died on 03/27/2005.

Prograf Side Effects Report #4822733-5
Prograf side effect was reported by a Physician from JAPAN on Oct 27, 2005. Male patient, weighting 20.50 lb, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: culture throat positive, depressed level of consciousness, enterobacter infection, haemodialysis, intraventricular haemorrhage, multi-organ failure, pseudomonas infection, renal failure acute, sepsis . Prograf dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, ALKERAN, PREDNISOLONE. Patient died on 03/27/2005.

Prograf Side Effects Report #4910007-3
Prograf side effect was reported by a Physician from JAPAN on Jan 27, 2006. Female patient, 77 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: depressed level of consciousness, hallucination, visual, persecutory delusion, psychomotor hyperactivity, toxic induced encephalopathy. Prograf dosage: 1 MG,BID, ORAL. During the same period patient was treated with NEO DOPASTON, SELEGILINE HYDROCHLORIDE, PERMAX. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4921141-6
Prograf side effect was reported by a Physician from JAPAN on Feb 08, 2006. Female patient, 77 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: activities of daily living impaired, depressed level of consciousness, hallucination, visual, persecutory delusion, psychomotor hyperactivity, toxic induced encephalopathy. Prograf dosage: 1 MG, BID, ORAL. During the same period patient was treated with NEO DOPASTON, SELEGILINE HYDROCHLORIDE, PERMAX. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5037346-2
Prograf side effect was reported by a Physician from JAPAN on June 08, 2006. Male patient, 63 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness. Prograf dosage: 0.5 MG, ORAL. During the same period patient was treated with TAKEPRON, GASTER DLET, DORNER, BLOPRESS, RENIVACE. Patient recovered.