Prograf and blood lactate dehydrogenase increased Patient Reports February 11, 2012

Prograf Side Effects Report #5509569-7
Prograf side effect was reported by a Health Professional from FRANCE on Oct 19, 2007. Female patient, 64 years of age, was diagnosed with transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: ascites, bacterial infection , blood culture positive, blood lactate dehydrogenase increased, dialysis , escherichia infection, hypertensive crisis, inflammation. Prograf dosage: 3 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE, CELLCEPT, ROVALCYTE, NEURONTIN, CLONAZEPAM, COLECALCIFEROL, PRAVASTATIN, IMOVANE. Patient died on 05/02/2007.

Prograf Side Effects Report #5492842-9
Prograf side effect was reported by a Physician from AUSTRALIA on Oct 05, 2007. Male patient, 39 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, blood lactate dehydrogenase decreased, blood lactate dehydrogenase increased, colonic polyp , diarrhoea, disease progression, hepatic function abnormal, hepatosplenomegaly. Prograf dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISOLONE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, ETANERCEPT. Patient died.

Prograf Side Effects Report #5753055-6
Prograf side effect was reported by a Health Professional from SWITZERLAND on May 09, 2008. Male patient, 26 years of age, was diagnosed with stem cell transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, haemoglobin decreased, kidney fibrosis, platelet count decreased, renal tubular atrophy, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with RAPAMUNE, CYCLOSPORINE, CELLCEPT, PREDNISOLONE ACETATE, DIFLUCAN, BACTRIM, FAMVIR. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5451883-8
Prograf side effect was reported by a Consumer or non-health professional from JAPAN on Aug 31, 2007. Female patient, 70 years of age, weighting 97.00 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, interstitial lung disease. Prograf dosage: 1.5 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, VOLTAREN, VOLTAREN CAPSULE, BACACIL, PARIET, ONEALFA, CYTOTEC, FOSAMAC. Patient died.


Prograf Side Effects Report #5467405-1
Prograf side effect was reported by a Physician from JAPAN on Sept 06, 2007. Female patient, 70 years of age, weighting 97.00 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, interstitial lung disease. Prograf dosage: 1.5 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, VOLTAREN, BACACIL, RABEPRAZOLE, ONEALFA, CYTOTEC, FOSAMAC, DIOVAN. Patient died on 08/31/2007.

Prograf Side Effects Report #5509573-9
Prograf side effect was reported by a Physician from JAPAN on Oct 24, 2007. Female patient, 70 years of age, weighting 97.00 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, diffuse alveolar damage, interstitial lung disease, no therapeutic response, rheumatoid lung. Prograf dosage: 1.5 MG, UID/QD, ORAL. During the same period patient was treated with PREDNISOLONE, VOLTAREN, BACACIL, RABEPRAZOLE, ONEALFA, CYTOTEC, FOSAMAC, DIOVAN. Patient died on 08/31/2007.

Prograf Side Effects Report #5859144-X
Prograf side effect was reported by a Physician from JAPAN on Aug 18, 2008. Female patient, 70 years of age, weighting 97.00 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, interstitial lung disease. Prograf dosage: 1.5 MG, UID/QD, ORAL. During the same period patient was treated with PREDONINE, VOLTAREN, BACACIL, RABEPRAZOLE, ONEALFA, CYTOTEC, FOSAMAC, DIOVAN. Patient died on 08/31/2007.

Prograf Side Effects Report #5921309-6
Prograf side effect was reported by a Physician from JAPAN on Oct 08, 2008. Female patient, 70 years of age, weighting 97.00 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, diffuse alveolar damage, dyspnoea exertional, interstitial lung disease, pulmonary fibrosis , rheumatoid lung. Prograf dosage: 1.5 MG, UID/QD; ORAL. During the same period patient was treated with PREDNISOLONE, VOLTAREN, VOLTAREN CAPSULE, BACACIL, PARIET, ONEALFA, CYTOTEC, FOSAMAC. Patient died on 08/31/2007.

Prograf Side Effects Report #4743993-5
Prograf side effect was reported by a Physician from JAPAN on July 28, 2005. Female patient, 51 years of age, weighting 92.60 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: antibody test abnormal, blood glucose increased, blood lactate dehydrogenase increased, hot flush, hypercapnia, insomnia, interleukin level increased, loss of consciousness. Prograf dosage: 3.00 MG UID/QD - SEE IMAGE. During the same period patient was treated with PREDNISOLONE, NEORAL, COTRIM, CLARITHROMYCIN, LANSOPRAZOLE, METHYCOBAL, RESPLEN, ETODOLAC. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #4777951-1
Prograf side effect was reported by a Physician from JAPAN on Sept 09, 2005. Female patient, 51 years of age, weighting 92.59 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood glucose increased, blood lactate dehydrogenase increased, hot flush, insomnia, loss of consciousness. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, NEORAL CAPSULE, BAKTAR SULFAMETHOXAZOLE, KLARICID, TAKEPRON. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #4795189-9
Prograf side effect was reported by a Physician from JAPAN on Sept 22, 2005. Female patient, 51 years of age, weighting 92.59 lb, was diagnosed with rheumatoid arthritis  and was treated with Prograf. After drug was administered, patient experienced the following side effects: antibody test abnormal, blood glucose increased, blood lactate dehydrogenase increased, hot flush, hypercapnia, insomnia, interstitial lung disease. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, NEORAL CAPSULE, BAKTAR, KLARICID, TAKEPRON. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5292086-X
Prograf side effect was reported by a Health Professional from FRANCE on Mar 21, 2007. Female patient, 68 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: atrial fibrillation , blood lactate dehydrogenase increased, cardiac arrest , coagulopathy, confusional state, dust inhalation pneumopathy, dyskinesia, haematemesis, haemoglobinuria. Prograf dosage: unknown. During the same period patient was treated with PLAVIX, PREDNISONE, KARDEGIC, CELLCEPT. Patient was hospitalized. Patient died on 10/17/2006.

Prograf Side Effects Report #5796961-9
Prograf side effect was reported by a Physician from AUSTRIA on June 12, 2008. Male patient, 63 years of age, weighting 251.3 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood cholesterol increased, blood lactate dehydrogenase increased, blood triglycerides increased, condition aggravated, diabetes mellitus, dialysis , glomerular filtration rate decreased, low density lipoprotein increased, platelet count increased. Prograf dosage: 8 MG ; 4 MG UID/QD ORAL. During the same period patient was treated with CORTICOSTEROIDS, MYCOPHENOLATE MOFETIL, DIURETICS, CALCIUM CHANNEL BLOCKERS, STATIN, INSULIN, BETA BLOCKING AGENTS, APREDNISLON. Patient recovered.

Prograf Side Effects Report #4762832-X
Prograf side effect was reported by a Consumer or non-health professional from FRANCE on Sept 05, 2005. Male patient, 58 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bilirubin conjugated increased, blood bicarbonate decreased, blood bilirubin increased, blood lactate dehydrogenase increased, blood lactic acid increased, c-reactive protein increased, depressed level of consciousness. Prograf dosage: 0.5 MG DAILY. During the same period patient was treated with CELLCEPT, ARANESP, TARDYFERON, FORTUM, LASILIX, EPREX, ALLOPURINOL, AMIKLIN. Patient was hospitalized. Patient died on 06/02/2005.


Prograf Side Effects Report #5649029-6
Prograf side effect was reported by a Physician from JAPAN on Feb 13, 2008. Female patient, 56 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: ascites, blood bilirubin increased, blood lactate dehydrogenase increased, haematocrit decreased, haemodialysis, haemoglobin decreased, thrombotic microangiopathy, transplant rejection. Prograf dosage: 0.15 MG/KG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, AZATHIOPRINE. Patient recovered.

Prograf Side Effects Report #5810749-1
Prograf side effect was reported by a Health Professional from UNITED STATES on June 30, 2008. Female patient, 51 years of age, was diagnosed with renal transplant, polyomavirus-associated nephropathy and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood lactate dehydrogenase increased, dialysis , ecchymosis, kidney transplant rejection, thrombocytopenia, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with LEFLUNOMIDE, ANTITHYMOCYTE IMMUNOGLOBULIN, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5878684-0
Prograf side effect was reported by a Physician from UNITED STATES on Aug 26, 2008. Female patient, 50 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, infection in an immunocompromised host, multi-organ failure, pulmonary alveolar haemorrhage, respiratory failure, strongyloidiasis, urinary tract infection . Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5429588-9
Prograf side effect was reported by a Physician from JAPAN on Aug 09, 2007. Female patient, 48 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain upper, arteritis, blood lactate dehydrogenase increased, capillary disorder, complications of transplanted kidney, disorientation, duodenitis, embolism, fibrin. Prograf dosage: 4 MG, BID,. During the same period patient was treated with BASILIXIMAB, MYCOPHENOLATE MOFETIL, METHYLPREDNISOLONE. Patient recovered.

Prograf Side Effects Report #5699320-2
Prograf side effect was reported by a Physician from UNITED STATES on Mar 26, 2008. Male patient, 46 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, blood lactate dehydrogenase increased, cardiac arrest , chills, dehydration, diarrhoea, haptoglobin increased, hydronephrosis, kidney transplant rejection. Prograf dosage: 4 MG, BID, ORAL 6 MG, BID. During the same period patient was treated with MYFORTIC, RAPAMUNE, LEVAQUIN, REGLAN, ASPIRIN, DAPSONE, NORVASC. Patient was hospitalized. Patient died on 03/12/2008.


Prograf Side Effects Report #6069114-7
Prograf side effect was reported by a Physician from SPAIN on Sept 23, 2008. Male patient, 41 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, blood culture positive, blood lactate dehydrogenase increased, candidiasis, granulocytopenia, hepatic enzyme increased, histiocytosis haematophagic, hyperbilirubinaemia. Prograf dosage: 10 MG. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, COTRIMOXAZOLE, VALGANCICLOVIR, ATG RABBIT, VANCOMYCIN HYDROCHLORIDE, CEFOTAXIME, FLUCONAZOLE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5143304-X
Prograf side effect was reported by a Health Professional from FRANCE on Oct 16, 2006. Female patient, 40 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood chloride decreased, blood fibrinogen increased, blood lactate dehydrogenase increased, blood ph increased, bradycardia, cardiac disorder, haemoglobin decreased, hyperkalaemia. Prograf dosage: unknown. During the same period patient was treated with CYMEVAN, WELLVONE, XIGRIS, BACTRIM, IMUREL. Patient died on 07/24/2006.

Prograf Side Effects Report #5550875-8
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient, 39 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood lactate dehydrogenase increased, haematochezia, haemoglobin decreased, orthostatic hypotension, platelet count decreased, red blood cell schistocytes present, small intestinal haemorrhage. Prograf dosage: 3.5 MG, UID/QD, ORAL. During the same period patient was treated with SIROLIMUS. Patient recovered.

Prograf Side Effects Report #6115934-X
Prograf side effect was reported by a Physician from JAPAN on Mar 06, 2009. Female patient, 39 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal distension, anaemia, blood lactate dehydrogenase increased, cardiovascular disorder, depressed level of consciousness, disseminated intravascular coagulation, gastrointestinal haemorrhage, hepatic function abnormal. Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient died on 05/03/2008.

Prograf Side Effects Report #5503552-3
Prograf side effect was reported by a Physician from JAPAN on Oct 15, 2007. Female patient, 25 years of age, weighting 90.39 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, complications of transplanted kidney, cytomegalovirus infection , disseminated intravascular coagulation, fungal infection , histiocytosis haematophagic, hyperbilirubinaemia, leukopenia, pneumocystis jiroveci pneumonia. Prograf dosage: 9 MG, ORAL; 12 MG, ORAL; 6 MG, UID/QD, ORAL; ORAL. During the same period patient was treated with PREDNISOLONE, AZATHIOPRINE PER ORAL NOS, FAMOTIDINE, CARVEDILOL. Patient died on 09/08/2001.


Prograf Side Effects Report #5503554-7
Prograf side effect was reported by a Physician from JAPAN on Oct 15, 2007. Male patient, 18 years of age, weighting 103.6 lb, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, blood amylase increased, blood lactate dehydrogenase increased, gastric ulcer. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5542842-5
Prograf side effect was reported by a Physician from UNITED STATES on Nov 27, 2007. Male patient, 17 years of age, was diagnosed with renal transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: biopsy kidney abnormal, blood fibrinogen decreased, blood lactate dehydrogenase increased, complement factor c3 decreased, fibrin d dimer increased, haemoglobin decreased, hydronephrosis, hypertension. Prograf dosage: 4 MG,BID. During the same period patient was treated with MYCOPHENOLATE MOFETIL, CYTOMEGALOVIRUS IMMUNE GLOBIN, VALGANCICLOVIR, FLUCONAZOLE, TRIMETHOPRIM COMP. Patient recovered.

Prograf Side Effects Report #5564529-5
Prograf side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient was diagnosed with renal and pancreas transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, cytomegalovirus infection , gastrointestinal haemorrhage, haematocrit decreased, haematuria, haemodialysis, kidney transplant rejection, pneumonia bacterial, proteinuria. Prograf dosage: 0.15 MG/KG. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.

Prograf Side Effects Report #5564532-5
Prograf side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient was diagnosed with renal and pancreas transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, complications of transplanted kidney, cytomegalovirus oesophagitis, gastrointestinal haemorrhage, haematocrit decreased, haematuria, haemodialysis, haemolytic uraemic syndrome, kidney transplant rejection. Prograf dosage: 0.15 MG/KG. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.

Prograf Side Effects Report #5564534-9
Prograf side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient was diagnosed with renal and pancreas transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, complications of transplanted kidney, cytomegalovirus oesophagitis, gastrointestinal haemorrhage, haematocrit decreased, haematuria, haemodialysis, haemolytic uraemic syndrome, kidney transplant rejection. Prograf dosage: 0.15 MG/KG. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.


Prograf Side Effects Report #5564536-2
Prograf side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient was diagnosed with renal and pancreas transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, complications of transplanted kidney, cytomegalovirus oesophagitis, gastrointestinal haemorrhage, haematocrit decreased, haematuria, haemodialysis, haemolytic uraemic syndrome, kidney transplant rejection. Prograf dosage: 0.15 MG/KG. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.

Prograf Side Effects Report #5564543-X
Prograf side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient was diagnosed with renal and pancreas transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, complications of transplanted kidney, cytomegalovirus oesophagitis, gastrointestinal haemorrhage, haematocrit decreased, haematuria, haemodialysis, haemolytic uraemic syndrome, kidney transplant rejection. Prograf dosage: 0.15 MG/KG. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.

Prograf Side Effects Report #5564559-3
Prograf side effect was reported by a Physician from BRAZIL on Nov 27, 2007. Female patient was diagnosed with renal and pancreas transplant and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, complications of transplanted kidney, cytomegalovirus oesophagitis, gastrointestinal haemorrhage, haematocrit decreased, haematuria, haemodialysis, haemolytic uraemic syndrome, kidney transplant rejection. Prograf dosage: 0.15 MG/KG. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.

Prograf Side Effects Report #5448924-0
Prograf side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2007. Female patient, 55 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, brain abscess, catheter related complication, clavicle fracture, deep vein thrombosis . Prograf dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE, ALENDRONATE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5023899-7
Prograf side effect was reported by a Physician from UNITED STATES on May 26, 2006. Male patient, 54 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, cardiac arrest , choriomeningitis lymphocytic, hypotension, infection in an immunocompromised host, leukopenia, multi-organ failure, post procedural complication, prothrombin time prolonged. Prograf dosage: unknown. Patient was hospitalized. Patient died.


Prograf Side Effects Report #5049209-7
Prograf side effect was reported by a Health Professional from FRANCE on Nov 16, 2004. Male patient, 47 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, haemoglobin decreased, haptoglobin decreased, platelet count decreased, renal failure acute, thrombotic microangiopathy. Prograf dosage: 4 MG 1X PER 1 DAY. During the same period patient was treated with CELLCEPT, PREDNISONE, ASPEGIC, OMEPRAZOLE, PROPRANOLOL, EUCALCIC, PRAVASTATIN, VALACYCLOVIR. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5451902-9
Prograf side effect was reported by a Physician from JAPAN on Aug 29, 2007. Male patient, 57 years of age, was diagnosed with myasthenia gravis, reflux oesophagitis, hypercholesterolaemia and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, malaise, white blood cell count increased. Prograf dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with FAMOTIDINE, LIPITOR, ISCOTIN, PURSENNID, MESTINON, ULCERLMIN, METHYCOBAL. Patient recovered.

Prograf Side Effects Report #5413442-2
Prograf side effect was reported by a Physician from JAPAN on July 27, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, interleukin level increased, lymphoproliferative disorder, no therapeutic response, osteomyelitis, pneumonia , respiratory disorder, transplant rejection. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5580096-4
Prograf side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, diarrhoea, eosinophil count increased, foreign body trauma, lymphoproliferative disorder, nausea , opportunistic infection. Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5580096-4
Prograf side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, diarrhoea, eosinophil count increased, lymphoproliferative disorder, opportunistic infection, osteomyelitis, pneumonia . Prograf dosage: unknown. Patient was hospitalized. Patient recovered.


Prograf Side Effects Report #5817459-5
Prograf side effect was reported by a Physician from JAPAN on July 03, 2008. Male patient, 38 years of age, weighting 108.0 lb, was diagnosed with lung transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood lactate dehydrogenase increased, bronchopulmonary aspergillosis, diarrhoea, epstein-barr virus associated lymphoproliferative disorder, lung transplant , no therapeutic response, osteomyelitis, pneumonia . Prograf dosage: unknown. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5060005-7
Prograf side effect was reported by a Physician from JAPAN on July 11, 2006. Male patient, 56 years of age, weighting 134.5 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: beta 2 microglobulin increased, beta 2 microglobulin urine increased, bile duct necrosis, blood bilirubin increased, blood lactate dehydrogenase increased, cardiac arrest , cardiac tamponade, catheter related complication, complications of transplanted liver. Prograf dosage: 8 MG. During the same period patient was treated with MEDROL ACETATE, PENTCILLIN, FLUMARIN, FUNGUARD, EPOGIN, HABEKACIN. Patient died on 09/11/2004.

Prograf Side Effects Report #5026934-5
Prograf side effect was reported by a Physician from JAPAN on May 26, 2006. Male patient, 56 years of age, weighting 134.5 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: beta 2 microglobulin increased, blood bilirubin increased, blood lactate dehydrogenase increased, cardiac arrest , cardiac tamponade, depressed level of consciousness, histiocytosis haematophagic, pancytopenia, respiratory arrest. Prograf dosage: 8 MG,. During the same period patient was treated with MEDROL ACETATE, PENTICILLIN, FLUMARIN, FUNGUARD, EPOGIN, HABEKACIN, CEFTAZIDIME. Patient died on 09/11/2004.

Prograf Side Effects Report #5044270-8
Prograf side effect was reported by a Physician from JAPAN on June 20, 2006. Male patient, 56 years of age, weighting 134.5 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: beta 2 microglobulin increased, blood bilirubin increased, blood lactate dehydrogenase increased, cardiac arrest , cardiac tamponade, depressed level of consciousness, dialysis , haematoma, histiocytosis haematophagic. Prograf dosage: unknown. During the same period patient was treated with MEDROL ACETATE, PIPERACILLIN, FLUMARIN, FUNGUARD, EPOGEN, HABEKACIN. Patient died on 09/11/2004.

Prograf Side Effects Report #5336431-5
Prograf side effect was reported by a Physician from JAPAN on May 09, 2007. Male patient, 54 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, cytomegalovirus infection , haemolysis, haemolytic anaemia, hepatitis , hepatitis c rna positive, intra-abdominal haemorrhage, multi-organ failure. Prograf dosage: unknown. During the same period patient was treated with GANCICLOVIR, INTRON A, RIBAVIRIN. Patient was hospitalized. Patient died.

Prograf Side Effects Report #5826889-7
Prograf side effect was reported by a Physician from JAPAN on July 16, 2008. Female patient, 53 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: anaemia, bacterial sepsis, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, coagulopathy, disease progression, disseminated intravascular coagulation, gamma-glutamyltransferase increased, hepatic failure. Prograf dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE. Patient died.

Prograf Side Effects Report #5989279-2
Prograf side effect was reported by a Consumer or non-health professional from JAPAN on Nov 28, 2008. Female patient, 50 years of age, weighting 121.3 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal infection, biliary tract infection, blood lactate dehydrogenase increased, haematoma infection, liver transplant , melaena, multi-organ failure, operative haemorrhage. Prograf dosage: 3 MG/D , ORAL. During the same period patient was treated with CELLCEPT, THYMOGLOBULINE, PROSTAGLANDIN E, ELASPOL, FUNGUARD. Patient was hospitalized. Patient died on 09/07/2007.

Prograf Side Effects Report #5954737-3
Prograf side effect was reported by a Physician from JAPAN on Nov 07, 2008. Female patient, 43 years of age, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: angiogram, aphasia , arteriogram abnormal, blood lactate dehydrogenase increased, cerebral artery stenosis, complications of transplanted liver, haemorrhagic cerebral infarction, hemiplegia, platelet count decreased. Prograf dosage: unknown. During the same period patient was treated with INTRON A, RIBAVIRIN, INTERFERON ALFA. Patient recovered.

Prograf Side Effects Report #4932373-5
Prograf side effect was reported by a Physician from JAPAN on Feb 17, 2006. Male patient, 34 years of age, weighting 207.9 lb, was diagnosed with liver transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acidosis, blood lactate dehydrogenase increased, cardiac arrest , complications of transplanted liver, depressed level of consciousness, hepatic artery occlusion, liver transplant rejection, pancytopenia, renal failure. Prograf dosage: unknown. During the same period patient was treated with CELLCEPT, PREDNISOLONE, SPANIDIN, VALIXA, BAKTAR, URSO, PARIET. Patient died on 01/17/2006.

Prograf Side Effects Report #5877452-3
Prograf side effect was reported by a Health Professional from UNITED STATES on Aug 22, 2008. Male patient, child 5 years of age, was diagnosed with heart transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, alopecia, blood alkaline phosphatase increased, blood amylase increased, blood bilirubin increased, blood lactate dehydrogenase increased, cholecystectomy, dehydration, diarrhoea. Prograf dosage: 5 MG, BID, UNK. Patient died.


Prograf Side Effects Report #5725821-4
Prograf side effect was reported by a Physician from UNITED STATES on Apr 18, 2008. Female patient, 29 years of age, weighting 244.3 lb, was diagnosed with heart transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, bacteraemia, blood bilirubin increased, blood bilirubin unconjugated increased, blood culture positive, blood glucose increased, blood lactate dehydrogenase increased, bradycardia, bronchoalveolar lavage abnormal. Prograf dosage: 4 MG, BID, ORAL; 1 MG, BID, ORAL. During the same period patient was treated with PREDNISOLONE ACETATE, RAPAMUNE, CARDIZEM CD, ALTACE, NEXIUM, PRAVACHOL. Patient was hospitalized. Patient died on 02/14/2008.

Prograf Side Effects Report #5023332-5
Prograf side effect was reported by a Physician from JAPAN on May 24, 2006. Male patient, 57 years of age, weighting 110.2 lb, was diagnosed with dermatomyositis and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, cytomegalovirus infection , dermatomyositis, hepatic function abnormal, interstitial lung disease, lymphocyte count decreased, respiratory failure. Prograf dosage: 3 MG, UID/QD, ORAL. During the same period patient was treated with CYCLOSPORINE, PREDNISOLONE, SULFAMETHOXAZOLE, CALCIUM LACTATE, ALFAROL, ZOLPIDEM TARTRATE, FUNGIZONE. Patient was hospitalized. Patient died on 07/28/2005.

Prograf Side Effects Report #5295764-1
Prograf side effect was reported by a Physician from FRANCE on Mar 23, 2007. Male patient, 25 years of age, was diagnosed with dermatitis atopic and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, dermatitis atopic, fatigue, insomnia, lymphoma , superinfection. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5306592-2
Prograf side effect was reported by a Physician from FRANCE on Apr 02, 2007. Male patient, 25 years of age, weighting 165.3 lb, was diagnosed with dermatitis atopic and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, dermatitis atopic, eczema , fatigue, insomnia, lymphadenopathy, lymphoma , superinfection. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5721421-0
Prograf side effect was reported by a Physician from JAPAN on Apr 16, 2008. Female patient, child 6 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, blood lactate dehydrogenase increased, cytomegalovirus enterocolitis, disease progression, malnutrition, renal impairment, sepsis , thrombotic microangiopathy, toxic encephalopathy. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, METHYLPREDNISOLONE, GANCICLOVIR. Patient died on 01/27/2007.

Prograf Side Effects Report #5974193-9
Prograf side effect was reported by a Physician from JAPAN on Nov 14, 2008. Male patient, 54 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood bilirubin unconjugated increased, blood lactate dehydrogenase increased, microangiopathic haemolytic anaemia, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, PREDNISONE, DEXAMETHASONE. Patient recovered.

Prograf Side Effects Report #5902813-3
Prograf side effect was reported by a Physician from JAPAN on Sept 18, 2008. Female patient, 48 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, red blood cell count increased, thrombotic microangiopathy. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE. Patient recovered.

Prograf Side Effects Report #5909475-X
Prograf side effect was reported by a Physician from JAPAN on Sept 25, 2008. Female patient, 48 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, renal impairment, thrombotic microangiopathy, venoocclusive liver disease. Prograf dosage: unknown. During the same period patient was treated with METHOTREXATE, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE. Patient died.

Prograf Side Effects Report #5096716-7
Prograf side effect was reported by a Physician from JAPAN on Aug 18, 2006. Female patient, 32 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, blood lactate dehydrogenase increased, red blood cell abnormality, stem cell transplant, thrombocytopenia, thrombotic microangiopathy. Prograf dosage: 0.03 MG/KG. During the same period patient was treated with METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL. Patient died on 10/20/2002.

Prograf Side Effects Report #4600549-2
Prograf side effect was reported by a Physician from on Feb 23, 2005. Male patient, 25 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, ascites, aspartate aminotransferase increased, blood bilirubin increased, blood lactate dehydrogenase increased, capillary leak syndrome, engraftment syndrome, haemodialysis, hypovolaemic shock. Prograf dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE. Patient died on 10/15/2004.


Prograf Side Effects Report #5678222-1
Prograf side effect was reported by a Physician from JAPAN on Mar 03, 2008. Male patient, child 10 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: abdominal pain , blood lactate dehydrogenase increased, epstein-barr virus infection, histiocytosis haematophagic, pyrexia, respiratory failure, serum ferritin increased. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, TRANILAST, MYCOPHENOLATE MOFETIL, THALIDOMIDE, OCTREOTIDE ACETATE, INFLIXIMAB, ETOPOSIDE. Patient died.

Prograf Side Effects Report #5728760-8
Prograf side effect was reported by a Physician from JAPAN on Apr 23, 2008. Male patient, child 10 years of age, was diagnosed with bone marrow transplant  and was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, histiocytosis haematophagic, infection , pancreatitis, pyrexia, respiratory failure. Prograf dosage: unknown. During the same period patient was treated with PREDNISOLONE, MYCOPHENOLATE MOFETIL. Patient died.

Prograf Side Effects Report #5504551-8
Prograf side effect was reported by a Physician from JAPAN on Oct 16, 2007. Male patient, 59 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, histiocytosis haematophagic, pyrexia, serum ferritin increased, weight increased. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5509949-X
Prograf side effect was reported by a Physician from JAPAN on Oct 24, 2007. Male patient, 59 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, histiocytosis haematophagic, pyrexia, rash , serum ferritin increased, weight increased. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5504526-9
Prograf side effect was reported by a Physician from JAPAN on Oct 16, 2007. Male patient, 31 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, histiocytosis haematophagic, serum ferritin increased, weight increased. Prograf dosage: unknown. Patient recovered.

Prograf Side Effects Report #5509926-9
Prograf side effect was reported by a Physician from JAPAN on Oct 24, 2007. Male patient, 31 years of age, was treated with Prograf. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, histiocytosis haematophagic, pyrexia, serum ferritin increased, weight increased. Prograf dosage: unknown. Patient recovered.