Pemetrexed and renal impairment Patient Reports February 12, 2012

Pemetrexed Side Effects Report #5394630-0
Pemetrexed side effect was reported by a Physician from JAPAN on July 13, 2007. Female patient, 77 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: aneurysm , atrial fibrillation , cardiac failure, hypoproteinaemia, oedema, renal impairment. Pemetrexed dosage: unknown. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5550583-3
Pemetrexed side effect was reported by a Physician from JAPAN on Nov 29, 2007. Female patient, 77 years of age, was diagnosed with pleural mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: aneurysm , atrial fibrillation , cardiac failure, hypoproteinaemia, oedema, renal impairment. Pemetrexed dosage: unknown. During the same period patient was treated with CISPLATIN. Patient recovered.

Pemetrexed Side Effects Report #5394631-2
Pemetrexed side effect was reported by a Physician from JAPAN on July 17, 2007. Male patient, 75 years of age, weighting 145.5 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: bone marrow failure, hepatic function abnormal, neutrophil count decreased, renal impairment. Pemetrexed dosage: 500 MG/M2, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, METHYCOBAL, SEROTONE, DECADRON, ROHYPNOL, NAUZELIN. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5442016-2
Pemetrexed side effect was reported by a Physician from JAPAN on Aug 27, 2007. Male patient, 75 years of age, weighting 145.5 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: bone marrow failure, hepatic function abnormal, neutrophil count decreased, renal impairment. Pemetrexed dosage: 500 MG/M2, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, METHYCOBAL, SEROTONE, DECADRON, ROHYPNOL, NAUZELIN. Patient was hospitalized. Patient recovered.


Pemetrexed Side Effects Report #5522149-2
Pemetrexed side effect was reported by a Physician from JAPAN on Nov 08, 2007. Male patient, weighting 102.5 lb, was diagnosed with pleural mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, lymphocyte count decreased, myelodysplastic syndrome, neutrophil count decreased, platelet count decreased, renal impairment, white blood cell count decreased. Pemetrexed dosage: 750 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, GEMCITABINE. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5533034-4
Pemetrexed side effect was reported by a Physician from JAPAN on Nov 20, 2007. Male patient, weighting 142.2 lb, was diagnosed with pleural mesothelioma malignant, gastritis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: bone marrow failure, hyperkalaemia, renal impairment. Pemetrexed dosage: 840 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, PROTECADIN. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5535864-1
Pemetrexed side effect was reported by a Physician from JAPAN on Nov 21, 2007. Male patient, weighting 123.0 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, neutrophil count decreased, platelet count decreased, renal impairment, shock, white blood cell count decreased. Pemetrexed dosage: 500 MG/M2, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, MASBLON H, NORVASC, FRANDOL, KYTRIL. Patient was hospitalized and became disabled. Patient recovered.

Pemetrexed Side Effects Report #5579253-2
Pemetrexed side effect was reported by a Physician from JAPAN on Dec 27, 2007. Male patient, weighting 102.5 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis, reflux oesophagitis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, lymphocyte count decreased, myelodysplastic syndrome, neutrophil count decreased, platelet count decreased, renal impairment, white blood cell count decreased. Pemetrexed dosage: 750 MG, OTHER. During the same period patient was treated with CISPLATIN, GEMCITABINE, CARBOPLATIN, PANVITAN, CYANOCOBALAMIN, KYTRIL, DECADRON, TAKEPRON. Patient was hospitalized. Patient died on 12/07/2007.

Pemetrexed Side Effects Report #5601395-3
Pemetrexed side effect was reported by a Physician from JAPAN on Jan 17, 2008. Male patient, weighting 102.5 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis, reflux oesophagitis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, infection , lymphocyte count decreased, myelodysplastic syndrome, neutrophil count decreased, platelet count decreased, renal impairment, white blood cell count decreased. Pemetrexed dosage: 750 MG, OTHER. During the same period patient was treated with CISPLATIN, GEMCITABINE, CARBOPLATIN, PANVITAN, CYANOCOBALAMIN, KYTRIL, DECADRON, TAKEPRON. Patient was hospitalized. Patient died on 12/07/2007.


Pemetrexed Side Effects Report #5602305-5
Pemetrexed side effect was reported by a Physician from JAPAN on Jan 11, 2008. Male patient, weighting 124.8 lb, was diagnosed with pleural mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, hepatic function abnormal, hypoalbuminaemia, lymphocyte count decreased, neoplasm progression, renal impairment. Pemetrexed dosage: 830 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, MYSLEE, LOXONIN, MEDICON. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5620743-1
Pemetrexed side effect was reported by a Physician from JAPAN on Jan 24, 2008. Male patient, weighting 142.2 lb, was diagnosed with pleural mesothelioma malignant, gastritis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: bone marrow failure, hyperkalaemia, renal impairment. Pemetrexed dosage: 840 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, PROTECADIN. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5691540-6
Pemetrexed side effect was reported by a Physician from JAPAN on Mar 21, 2008. Male patient, weighting 124.8 lb, was diagnosed with pleural mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, hepatic function abnormal, hypoalbuminaemia, lymphocyte count decreased, renal impairment. Pemetrexed dosage: 830 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, MYSLEE, LOXONIN, MEDICON. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5775589-0
Pemetrexed side effect was reported by a Physician from JAPAN on June 10, 2008. Male patient, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood lactate dehydrogenase increased, febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Pemetrexed dosage: 847 MG, OTHER. During the same period patient was treated with CISPLATIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN, MAGNESIUM OXIDE, NOVAMIN. Patient was hospitalized. Patient died on 05/01/2008.

Pemetrexed Side Effects Report #5809411-0
Pemetrexed side effect was reported by a Physician from JAPAN on July 08, 2008. Male patient, weighting 114.0 lb, was diagnosed with pleural mesothelioma malignant, cancer pain and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, gastrointestinal infection, platelet count decreased, renal impairment, white blood cell count decreased. Pemetrexed dosage: 730 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, LOXONIN. Patient died on 04/14/2008.


Pemetrexed Side Effects Report #5809412-2
Pemetrexed side effect was reported by a Physician from JAPAN on July 03, 2008. Male patient, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, diabetes mellitus, emphysema, cancer pain, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Pemetrexed dosage: 847 MG, OTHER. During the same period patient was treated with CISPLATIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN, MAGNESIUM OXIDE, NOVAMIN. Patient was hospitalized. Patient died on 05/13/2008.

Pemetrexed Side Effects Report #5863164-9
Pemetrexed side effect was reported by a Physician from JAPAN on Aug 21, 2008. Male patient, weighting 132.3 lb, was diagnosed with pleural mesothelioma malignant, diabetes mellitus, emphysema, cancer pain, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, febrile neutropenia, interstitial lung disease, liver disorder, platelet count decreased, renal impairment. Pemetrexed dosage: 847 MG, OTHER. During the same period patient was treated with CISPLATIN, AMARYL, BASEN, CELTECT, BISOLVON, OXYCONTIN, MAGNESIUM OXIDE, NOVAMIN. Patient was hospitalized. Patient died on 05/13/2008.

Pemetrexed Side Effects Report #5906828-0
Pemetrexed side effect was reported by a Physician from JAPAN on Sept 19, 2008. Male patient, weighting 114.0 lb, was diagnosed with pleural mesothelioma malignant, cancer pain and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, decreased appetite, gastrointestinal infection, ileus paralytic, melaena, platelet count decreased, renal impairment, restlessness, white blood cell count decreased. Pemetrexed dosage: 730 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, LOXONIN. Patient was hospitalized. Patient died on 04/14/2008.

Pemetrexed Side Effects Report #6107447-6
Pemetrexed side effect was reported by a Physician from JAPAN on Feb 27, 2009. Male patient, weighting 136.7 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: renal impairment. Pemetrexed dosage: 850 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, NASEA. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #4705506-3
Pemetrexed side effect was reported by a Health Professional from on June 13, 2005. Male patient, 61 years of age, weighting 154.3 lb, was diagnosed with non-small cell lung cancer and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: peripheral ischaemia, renal impairment, renal infarct. Pemetrexed dosage: 500 MG/M2. During the same period patient was treated with CISPLATIN, ACETAMINOPHEN, NADROPARINE CALCIUM, SIMVASTATIN, PIRACETAM, FOLIC ACID, DEXAMETHASONE. Patient was hospitalized. Patient recovered.


Pemetrexed Side Effects Report #4707288-8
Pemetrexed side effect was reported by a Consumer or non-health professional from BELGIUM on June 13, 2005. Male patient, 61 years of age, weighting 154.3 lb, was diagnosed with non-small cell lung cancer and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: ischaemia, renal impairment, renal infarct. Pemetrexed dosage: 500 MG/M2. During the same period patient was treated with CISPLATIN, ACETAMINOPHEN, NADROPARINE CALCIUM, SIMVASTATIN, PIRACETAM, FOLIC ACID, VITAMIN B. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #4724430-3
Pemetrexed side effect was reported by a Consumer or non-health professional from BELGIUM on July 01, 2005. Male patient, 61 years of age, weighting 154.3 lb, was diagnosed with non-small cell lung cancer and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, haemoglobin decreased, hepatic cyst, metastases to liver, peripheral ischaemia, renal impairment, renal infarct. Pemetrexed dosage: 500 MG/M2. During the same period patient was treated with CISPLATIN, ACETAMINOPHEN, NADROPARINE CALCIUM, SIMVASTATIN, PIRACETAM, FOLIC ACID, VITAMIN B. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #4860845-0
Pemetrexed side effect was reported by a Consumer or non-health professional from BELGIUM on Nov 30, 2005. Male patient, 61 years of age, weighting 155.2 lb, was diagnosed with non-small cell lung cancer and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: haemoglobin decreased, hepatic cyst, metastases to liver, renal impairment, renal infarct, thrombosis, white blood cell count increased. Pemetrexed dosage: 500 MG/M2, INTRAVENOUS. During the same period patient was treated with CISPLATIN, PARACETAMOL, NADROPARINE CALCIUM, SIMVASTATIN, PIRACETAM, FOLIC ACID, VITAMIN B12. Patient was hospitalized. Patient recovered.