Pemetrexed and malignant neoplasm progression Patient Reports February 12, 2012

Pemetrexed Side Effects Report #5533031-9
Pemetrexed side effect was reported by a Physician from JAPAN on Nov 27, 2007. Female patient, weighting 132.5 lb, was diagnosed with pleural mesothelioma malignant, prophylaxis, cholelithiasis, hypertension, hyperlipidaemia and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: cholecystitis, diarrhoea, malignant neoplasm progression, pseudomonal sepsis. Pemetrexed dosage: 500 MG/M2, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, HYDROXOCOBALAMIN ACETATE, GASTER, OMEPRAL, URSO, NORVASC, LIPITOR. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5878007-7
Pemetrexed side effect was reported by a Physician from JAPAN on Aug 29, 2008. Female patient, weighting 133.8 lb, was diagnosed with pleural mesothelioma malignant, cancer pain and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: interstitial lung disease, malignant neoplasm progression, mitral valve incompetence, neutrophil count decreased, platelet count decreased, pneumonia bacterial, white blood cell count decreased. Pemetrexed dosage: 500 MG/M2, OTHER. During the same period patient was treated with CARBOPLATIN, PANVITAN, CYANOCOBALAMIN, OXYCONTIN, TEGRETOL, NOVAMIN, LOXOPROFEN, ADALAT CR. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5923160-X
Pemetrexed side effect was reported by a Physician from JAPAN on Oct 10, 2008. Male patient, weighting 104.3 lb, was diagnosed with pleural mesothelioma malignant, cancer pain and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: dementia , depressed level of consciousness, gastrointestinal infection, haematochezia, hypertension, ileus paralytic, malignant neoplasm progression, melaena, pancytopenia. Pemetrexed dosage: 730 MG, OTHER. During the same period patient was treated with CISPLATIN, PANVITAN, CYANOCOBALAMIN, LOXONIN. Patient was hospitalized. Patient died on 04/14/2008.

Pemetrexed Side Effects Report #6009984-1
Pemetrexed side effect was reported by a Physician from JAPAN on Dec 05, 2008. Male patient, weighting 161.6 lb, was diagnosed with pleural mesothelioma malignant, gastritis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, blood creatinine increased, bone marrow failure, lung infiltration, lymphocyte count decreased, malignant neoplasm progression, neutrophil count decreased, organising pneumonia. Pemetrexed dosage: unknown. During the same period patient was treated with CISPLATIN, PARAPLATIN, PANVITAN, CYANOCOBALAMIN, RABEPRAZOLE. Patient was hospitalized. Patient recovered.


Pemetrexed Side Effects Report #4565324-6
Pemetrexed side effect was reported by a Physician from on Jan 10, 2005. Male patient, 63 years of age, weighting 132.3 lb, was diagnosed with peritoneal mesothelioma malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: aplasia, bone marrow depression, hypocalcaemia, hypokalaemia, hypomagnesaemia, hyponatraemia, hypophosphataemia, malignant neoplasm progression, nephritis interstitial. Pemetrexed dosage: 500 MG/M2 /1 OTHER. During the same period patient was treated with CISPLATIN, FOLIC ACID, VITAMIN B, DEXAMETHASONE. Patient was hospitalized. Patient died on 05/13/2004.

Pemetrexed Side Effects Report #5670467-X
Pemetrexed side effect was reported by a Consumer or non-health professional from GERMANY on Mar 05, 2008. Male patient, weighting 136.7 lb, was diagnosed with non-small cell lung cancer stage iv and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, malignant neoplasm progression, mucosal inflammation, thrombocytopenia. Pemetrexed dosage: unknown. Patient was hospitalized. Patient died on 02/12/2008.

Pemetrexed Side Effects Report #5700236-3
Pemetrexed side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 04, 2008. Male patient, weighting 136.7 lb, was diagnosed with non-small cell lung cancer stage iv and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, malignant neoplasm progression, mucosal inflammation, thrombocytopenia. Pemetrexed dosage: unknown. Patient was hospitalized. Patient died on 02/12/2008.

Pemetrexed Side Effects Report #5150883-5
Pemetrexed side effect was reported by a Consumer or non-health professional from GREECE on Apr 10, 2006. Male patient, 76 years of age, weighting 187.4 lb, was diagnosed with non-small cell lung cancer, soft tissue infection, bone pain and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: erythema multiforme, jaundice , malignant neoplasm progression, neutropenia, thrombocytopenia. Pemetrexed dosage: unknown. During the same period patient was treated with FUCIDIN, ZOMETA. Patient was hospitalized. Patient died.

Pemetrexed Side Effects Report #5217208-8
Pemetrexed side effect was reported by a Physician from UNITED KINGDOM on Jan 15, 2007. Male patient, 63 years of age, weighting 138.5 lb, was diagnosed with non-small cell lung cancer, prophylaxis, constipation , appetite disorder, pain , nausea , gastrooesophageal reflux disease and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemorrhagic disorder, haemothorax, international normalised ratio increased, malignant neoplasm progression, peripheral circulatory failure, pleural effusion, prothrombin time prolonged, respiratory distress. Pemetrexed dosage: 825 MG, OTHER. During the same period patient was treated with FOLIC ACID, VITAMIN B, MEGESTROL ACETATE, METOCLOPRAMIDE, ORAMORPH, LANSOPRAZOLE. Patient was hospitalized. Patient died on 05/11/2005.


Pemetrexed Side Effects Report #4662788-4
Pemetrexed side effect was reported by a Physician from on Apr 25, 2005. Male patient, 62 years of age, weighting 152.1 lb, was diagnosed with non-small cell lung cancer and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, haemoglobin decreased, heart rate increased, lymphocyte count decreased, malignant neoplasm progression, neutrophil count decreased, oxygen saturation decreased, performance status decreased, platelet count decreased. Pemetrexed dosage: 1750 MG OTHER. During the same period patient was treated with PANVITAN, HYDROXOCOBALAMIN ACETATE, ACECOL, MERISLON, EUGLUCON, CEPHADOL. Patient recovered.

Pemetrexed Side Effects Report #5406469-8
Pemetrexed side effect was reported by a Physician from RUSSIAN FEDERATION on July 26, 2007. Male patient, 55 years of age, was diagnosed with non-small cell lung cancer and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: malignant neoplasm progression. Pemetrexed dosage: unknown. During the same period patient was treated with FOLIC ACID, VITAMIN B, VERAPAMIL, DEXAMETHASONE, CIPROFLOXACIN, EUPHYLLIN. Patient was hospitalized. Patient died on 06/22/2006.

Pemetrexed Side Effects Report #5492802-8
Pemetrexed side effect was reported by a Physician from KOREA, REPUBLIC OF on Oct 18, 2007. Male patient, weighting 125.0 lb, was diagnosed with non-small cell lung cancer, nausea  and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, nephrotic syndrome. Pemetrexed dosage: unknown. During the same period patient was treated with CARBOPLATIN, FOLIC ACID, VITAMIN B, DEXAMETHASONE, GRANISETRON. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #6132213-5
Pemetrexed side effect was reported by a Physician from KOREA, REPUBLIC OF on Mar 13, 2009. Male patient, weighting 125.0 lb, was diagnosed with non-small cell lung cancer, nausea  and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, nephrotic syndrome. Pemetrexed dosage: unknown. During the same period patient was treated with CARBOPLATIN, FOLIC ACID, VITAMIN B, DEXAMETHASONE, GRANISETRON, DEXTROSE. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #4833450-X
Pemetrexed side effect was reported by a Consumer or non-health professional from BELGIUM on Sept 21, 2005. Male patient, 72 years of age, weighting 138.9 lb, was diagnosed with mesothelioma  and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: epilepsy , malignant neoplasm progression, mesothelioma , metastases to central nervous system. Pemetrexed dosage: 850 MG/1 OTHER. During the same period patient was treated with CARBOPLATIN, DEXAMETHASONE, ZOFRAN, DOLZAM, ACETAMINOPHEN, TILDIEM RETARD, ACETYLSALICYLIC ACID SRT, OMEPRAZOLE. Patient was hospitalized. Patient recovered.


Pemetrexed Side Effects Report #4883079-2
Pemetrexed side effect was reported by a Consumer or non-health professional from BELGIUM on Dec 23, 2005. Male patient, 72 years of age, weighting 139.6 lb, was diagnosed with mesothelioma  and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: angina pectoris, epilepsy , malignant neoplasm progression, mesothelioma , metastases to central nervous system. Pemetrexed dosage: 850 MG, OTHER, INTRAVENOUS. During the same period patient was treated with CARBOPLATIN, DEXAMETHASONE, ZOFRAN, DOLZAM, ACETAMINOPHEN, TILDIEM RETARD, ACETYLSALICYLIC ACID SRT, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Pemetrexed Side Effects Report #5071752-5
Pemetrexed side effect was reported by a Physician from FRANCE on July 20, 2006. Female patient, 50 years of age, was diagnosed with lung neoplasm malignant and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: hepatocellular damage, lung neoplasm malignant, malignant neoplasm progression. Pemetrexed dosage: unknown. Patient recovered.

Pemetrexed Side Effects Report #5270267-9
Pemetrexed side effect was reported by a Physician from FRANCE on Mar 13, 2007. Male patient, 52 years of age, weighting 224.9 lb, was diagnosed with carcinoma in situ of trachea, vitamin supplementation, prophylaxis and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: anaemia, blood creatine increased, catheter site phlebitis, diabetes mellitus, gamma-glutamyltransferase increased, hepatic function abnormal, interstitial lung disease, malignant neoplasm progression, pericarditis. Pemetrexed dosage: 500 MG/M2, OTHER. During the same period patient was treated with SPECIAFOLDINE, VITAMIN B, DEXAMETHASONE, CORTANCYL, SKENAN, MESTINON. Patient was hospitalized. Patient died on 10/21/2006.

Pemetrexed Side Effects Report #4901165-5
Pemetrexed side effect was reported by a Health Professional from POLAND on Jan 12, 2006. Female patient, 51 years of age, weighting 112.4 lb, was diagnosed with breast cancer  and was treated with Pemetrexed. After drug was administered, patient experienced the following side effects: fatigue, malignant neoplasm progression. Pemetrexed dosage: 2664 MG, INTRAVENOUS. During the same period patient was treated with CYCLOPHOSPHAMIDE, FOLIC ACID, VITAMIN B12, MORPHINE, ZOFRAN. Patient died on 11/30/2005.