Pazopanib and fatigue Patient Reports February 11, 2012

Pazopanib Side Effects Report #5830213-3
Pazopanib side effect was reported by a Physician from UNITED STATES on July 25, 2008. Female patient, 61 years of age, was diagnosed with neoplasm malignant and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, dehydration, fatigue, hepatic enzyme increased, pyrexia. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with PACLITAXEL, LAPATINIB. Patient was hospitalized. Patient recovered.

Pazopanib Side Effects Report #5314785-3
Pazopanib side effect was reported by a Physician from UNITED STATES on Apr 27, 2007. Male patient, 76 years of age, weighting 188.3 lb, was diagnosed with malignant glioma, hypertension, convulsion prophylaxis and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: asthenia, blood pressure increased, bradycardia, circulatory collapse, constipation , convulsion, dehydration, fatigue, motor dysfunction. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB, LISINOPRIL, KEPPRA. Patient was hospitalized. Patient recovered.

Pazopanib Side Effects Report #5321439-6
Pazopanib side effect was reported by a Physician from UNITED STATES on May 02, 2007. Male patient, 76 years of age, weighting 188.3 lb, was diagnosed with malignant glioma, hypertension, convulsion prophylaxis and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: asthenia, blood pressure increased, bradycardia, circulatory collapse, constipation , convulsion, dehydration, fatigue, motor dysfunction. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB, LISINOPRIL, KEPPRA. Patient was hospitalized. Patient recovered.

Pazopanib Side Effects Report #5333660-1
Pazopanib side effect was reported by a Physician from UNITED STATES on May 22, 2007. Male patient, 76 years of age, weighting 188.3 lb, was diagnosed with malignant glioma, hypertension, convulsion prophylaxis and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: asthenia, blood pressure increased, bradycardia, circulatory collapse, constipation , convulsion, dehydration, fatigue, motor dysfunction. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB, LISINOPRIL, KEPPRA. Patient was hospitalized. Patient recovered.


Pazopanib Side Effects Report #5340158-3
Pazopanib side effect was reported by a Physician from UNITED STATES on May 24, 2007. Male patient, 76 years of age, weighting 188.3 lb, was diagnosed with malignant glioma, hypertension, convulsion prophylaxis and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: asthenia, blood pressure increased, bradycardia, circulatory collapse, constipation , convulsion, dehydration, fatigue, motor dysfunction. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB, LISINOPRIL, KEPPRA. Patient was hospitalized. Patient recovered.

Pazopanib Side Effects Report #6015905-8
Pazopanib side effect was reported by a Physician from UNITED KINGDOM on Dec 17, 2008. Male patient, 49 years of age, weighting 178.4 lb, was diagnosed with malignant glioma, convulsion, fatigue, prophylaxis against gastrointestinal ulcer, headache  and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: cardiac arrest , circulatory collapse, dyspnoea, fatigue, hypoxia, nausea , pulmonary embolism , sinus tachycardia, syncope. Pazopanib dosage: 600MG TWICE PER DAY. During the same period patient was treated with LAPATINIB, PHENYTOIN, TEGRETOL, DEXAMETHASONE, ONDANSETRON, CODEINE PHOSPHATE. Patient was hospitalized. Patient died on 12/15/2008.

Pazopanib Side Effects Report #6092271-3
Pazopanib side effect was reported by a Physician from UNITED KINGDOM on Feb 16, 2009. Male patient, 49 years of age, weighting 178.4 lb, was diagnosed with malignant glioma, fatigue, headache  and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: cardiac arrest , circulatory collapse, dyspnoea, fatigue, hypoxia, nausea , pulmonary embolism , sinus tachycardia, syncope. Pazopanib dosage: 600MG TWICE PER DAY. During the same period patient was treated with LAPATINIB, PHENYTOIN, TEGRETOL, DEXAMETHASONE, ONDANSETRON, CODEINE PHOSPHATE. Patient was hospitalized. Patient died on 12/15/2008.

Pazopanib Side Effects Report #5853954-0
Pazopanib side effect was reported by a Physician from UNITED KINGDOM on Aug 19, 2008. Male patient, weighting 209.7 lb, was diagnosed with malignant glioma, headache , epilepsy  and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: aggression, confusional state, dehydration, diarrhoea, electrocardiogram change, fatigue, hypotension, lethargy, pericarditis. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB, DEXAMETHASONE, ORAMORPH, VALPROATE, LAMOTRIGINE, PHENYTOIN, LANSOPRAZOLE. Patient was hospitalized and became disabled. Patient recovered.

Pazopanib Side Effects Report #5865213-0
Pazopanib side effect was reported by a Physician from UNITED KINGDOM on Aug 22, 2008. Male patient, weighting 209.7 lb, was diagnosed with malignant glioma, headache , epilepsy  and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: aggression, confusional state, dehydration, diarrhoea, electrocardiogram change, fatigue, hypotension, lethargy, pericarditis. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB, DEXAMETHASONE, ORAMORPH, VALPROATE, LAMOTRIGINE, PHENYTOIN, LANSOPRAZOLE. Patient was hospitalized and became disabled. Patient recovered.


Pazopanib Side Effects Report #5870611-5
Pazopanib side effect was reported by a Physician from UNITED KINGDOM on Aug 28, 2008. Male patient, weighting 209.7 lb, was diagnosed with malignant glioma, headache , epilepsy  and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: aggression, confusional state, dehydration, diarrhoea, electrocardiogram change, fatigue, hypotension, lethargy, pericarditis. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB, DEXAMETHASONE, ORAMORPH, VALPROATE, LAMOTRIGINE, PHENYTOIN, LANSOPRAZOLE. Patient was hospitalized and became disabled. Patient recovered.

Pazopanib Side Effects Report #5877933-2
Pazopanib side effect was reported by a Physician from UNITED KINGDOM on Sept 05, 2008. Male patient, weighting 209.7 lb, was diagnosed with malignant glioma, headache , epilepsy , prophylaxis against gastrointestinal ulcer and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: abdominal pain lower, aggression, confusional state, dehydration, diarrhoea, electrocardiogram change, fatigue, fistula , hypotension. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB, DEXAMETHASONE, ORAMORPH, VALPROATE, LAMOTRIGINE, PHENYTOIN, LANSOPRAZOLE, METOCLOPRAMIDE. Patient was hospitalized and became disabled. Patient recovered.

Pazopanib Side Effects Report #5670884-8
Pazopanib side effect was reported by a Physician from UNITED STATES on Mar 17, 2008. Female patient, 36 years of age, weighting 191.8 lb, was diagnosed with cervix carcinoma and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: abasia, cardiac arrest , dyspnoea, eating disorder , fatigue, nausea , pleural effusion, respiratory distress. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient died on 02/13/2008.

Pazopanib Side Effects Report #5925591-0
Pazopanib side effect was reported by a Physician from ISRAEL on Oct 16, 2008. Female patient, 45 years of age, weighting 119.9 lb, was diagnosed with breast cancer metastatic and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: blood creatinine increased, dehydration, diarrhoea, fatigue, vomiting. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient recovered.

Pazopanib Side Effects Report #5836829-2
Pazopanib side effect was reported by a Physician from UNITED STATES on Aug 01, 2008. Female patient, 61 years of age, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: bacteraemia, fatigue, hepatic enzyme increased, pyrexia. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with PACLITAXEL, LAPATINIB. Patient was hospitalized. Patient recovered.


Pazopanib Side Effects Report #5566782-0
Pazopanib side effect was reported by a Physician from INDIA on Dec 18, 2007. Female patient, 55 years of age, weighting 99.21 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: circulatory collapse, fatigue, retching, vomiting. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB, LOPERAMIDE. Patient died on 12/08/2007.

Pazopanib Side Effects Report #5601267-4
Pazopanib side effect was reported by a Physician from INDIA on Jan 16, 2008. Female patient, 55 years of age, weighting 99.21 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: circulatory collapse, fatigue, retching, vomiting. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB, LOPERAMIDE. Patient died on 12/08/2007.

Pazopanib Side Effects Report #5700285-5
Pazopanib side effect was reported by a Physician from INDIA on Mar 30, 2008. Female patient, 55 years of age, weighting 99.21 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: circulatory collapse, fatigue, retching, vomiting. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB, LOPERAMIDE. Patient died on 12/08/2007.

Pazopanib Side Effects Report #6004022-9
Pazopanib side effect was reported by a Physician from ISRAEL on Dec 11, 2008. Female patient, 45 years of age, weighting 119.9 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: blood creatinine increased, dehydration, diarrhoea, fatigue, vomiting. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient recovered.

Pazopanib Side Effects Report #5505301-1
Pazopanib side effect was reported by a Physician from THAILAND on Oct 31, 2007. Female patient, 39 years of age, weighting 101.4 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: fatigue. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient died on 10/17/2007.


Pazopanib Side Effects Report #5534434-9
Pazopanib side effect was reported by a Physician from THAILAND on Dec 02, 2007. Female patient, 39 years of age, weighting 101.4 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: fatigue, oral intake reduced. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient died on 10/17/2007.

Pazopanib Side Effects Report #5648636-4
Pazopanib side effect was reported by a Physician from THAILAND on Feb 28, 2008. Female patient, 39 years of age, weighting 101.4 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: fatigue, oral intake reduced, respiratory failure. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient died on 10/17/2007.

Pazopanib Side Effects Report #5708112-7
Pazopanib side effect was reported by a Physician from THAILAND on Apr 11, 2008. Female patient, 39 years of age, weighting 101.4 lb, was treated with Pazopanib. After drug was administered, patient experienced the following side effects: fatigue, oral intake reduced, respiratory failure. Pazopanib dosage: 400MG PER DAY. During the same period patient was treated with LAPATINIB. Patient was hospitalized. Patient died on 10/18/2007.

Pazopanib Side Effects Report #5700288-0
Pazopanib side effect was reported by a Physician from UNITED STATES on Apr 04, 2008. Female patient, 36 years of age, weighting 191.8 lb, was diagnosed with fluid overload and was treated with Pazopanib. After drug was administered, patient experienced the following side effects: abasia, cardiac arrest , dyspnoea, eating disorder , fatigue, nausea , pleural effusion, respiratory distress. Pazopanib dosage: 800MG PER DAY. During the same period patient was treated with LAPATINIB, LASIX, PREDNISONE, OXYCONTIN, DEXMEDETOMIDINE HYDROCHLORIDE, CEFAZOLIN. Patient was hospitalized. Patient died on 02/13/2008.