Pamidronate and malignant neoplasm progression Patient Reports February 12, 2012

Pamidronate Side Effects Report #4910687-2
Pamidronate side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 07, 2006. Male patient, 70 years of age, was diagnosed with multiple myeloma , anaemia, constipation  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: deep vein thrombosis , hyperglycaemia, impaired healing, malignant neoplasm progression, osteonecrosis , tooth extraction. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with DEXAMETHASONE, CYCLOPHOSPHAMIDE, PREDNISONE, DARBEPOETIN ALFA, PROCRIT, COLACE, SENOKOT. Patient died on 09/08/2005.

Pamidronate Side Effects Report #4865742-2
Pamidronate side effect was reported by a Health Professional from AUSTRALIA on Dec 12, 2005. Male patient, 64 years of age, was diagnosed with multiple myeloma  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone disorder, bone lesion excision, exostosis of external ear canal, impaired healing, malignant neoplasm progression, mouth ulceration, osteonecrosis , periodontal disease, primary sequestrum. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with INTERFERON ALFA, ZOLEDRONATE, DEXAMETHASONE, LENALIDOMIDE. Patient recovered.

Pamidronate Side Effects Report #5298625-7
Pamidronate side effect was reported by a Health Professional from UNITED KINGDOM on Apr 11, 2007. Female patient, 56 years of age, was diagnosed with multiple myeloma  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: blood parathyroid hormone increased, bone disorder, fibrosis, high turnover osteopathy, hyperparathyroidism secondary, hypocalcaemia, malignant neoplasm progression, osteoprotegerin ligand, renal impairment. Pamidronate dosage: unknown. During the same period patient was treated with THALIDOMIDE. Patient died.

Pamidronate Side Effects Report #5143205-7
Pamidronate side effect was reported by a Health Professional from UNITED KINGDOM on Oct 27, 2006. Female patient, 56 years of age, was diagnosed with multiple myeloma  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: blood parathyroid hormone increased, bone disorder, fibrosis, high turnover osteopathy, hyperparathyroidism secondary, hypocalcaemia, malignant neoplasm progression, osteoprotegerin ligand, renal impairment. Pamidronate dosage: unknown. During the same period patient was treated with THALIDOMIDE. Patient died.


Pamidronate Side Effects Report #5167480-8
Pamidronate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 17, 2006. Female patient, 56 years of age, was diagnosed with multiple myeloma  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: blood parathyroid hormone increased, bone disorder, fibrosis, high turnover osteopathy, hyperparathyroidism secondary, hypocalcaemia, malignant neoplasm progression, multiple myeloma , osteoprotegerin ligand. Pamidronate dosage: unknown. During the same period patient was treated with THALIDOMIDE. Patient died.

Pamidronate Side Effects Report #4885326-X
Pamidronate side effect was reported by a Physician from BELGIUM on Jan 11, 2006. Female patient was diagnosed with multiple myeloma  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone disorder, malignant neoplasm progression, osteonecrosis , renal failure. Pamidronate dosage: 60 MG. During the same period patient was treated with ALKERAN, MEDROL, ZOMETA. Patient recovered.

Pamidronate Side Effects Report #4764535-4
Pamidronate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 31, 2005. Female patient, 68 years of age, was diagnosed with metastases to bone and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone debridement, bone trimming, impaired healing, inflammation, malignant neoplasm progression, metastases to lung, oral pain, osteomyelitis. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with PEGFILGRASTIM, ZOLEDRONATE, EXEMESTANE, VINORELBINE, MEDROXYPROGESTERONE ACETATE. Patient recovered.

Pamidronate Side Effects Report #4778665-4
Pamidronate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 31, 2005. Female patient, 68 years of age, was diagnosed with metastases to bone and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone debridement, bone pain, bone trimming, carbohydrate antigen 15-3 increased, impaired healing, inflammation, malignant neoplasm progression, metastases to lung. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with PEGFILGRASTIM, ZOLEDRONATE, EXEMESTANE, VINORELBINE, MEDROXYPROGESTERONE ACETATE. Patient recovered.

Pamidronate Side Effects Report #5470325-X
Pamidronate side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Sept 10, 2007. Female patient was diagnosed with metastases to bone and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: breast cancer , infection , malignant neoplasm progression, metastases to bone, multimorbidity, neuralgia, osteonecrosis . Pamidronate dosage: 60 MG FREQ IV. During the same period patient was treated with PAMIDRONATE DI, ZOMETA. Patient recovered.


Pamidronate Side Effects Report #4603026-8
Pamidronate side effect was reported by a Health Professional from on June 23, 2004. Female patient, 51 years of age, was diagnosed with hypercalcaemia of malignancy and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: confusional state, malignant neoplasm progression, metastases to central nervous system. Pamidronate dosage: 120 MG, UNK. During the same period patient was treated with DOXORUBICIN, DOCETAXEL, ZOLEDRONATE. Patient died.

Pamidronate Side Effects Report #5578536-X
Pamidronate side effect was reported by a Health Professional from UNITED KINGDOM on Dec 18, 2007. Male patient was diagnosed with hypercalcaemia of malignancy and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: condition aggravated, hypercalcaemia of malignancy, malignant neoplasm progression, metastases to central nervous system, metastases to lung, metastatic renal cell carcinoma, no therapeutic response. Pamidronate dosage: 120 MG FREQ IV. During the same period patient was treated with ZOMETA, CALCITONIN SALMON, CALCITONIN SALMON, IBANDRONIC ACID, CLARITHROMYCIN, DEXAMETHASONE, GABAPENTIN, NYSTATIN. Patient died on 08/20/2007.

Pamidronate Side Effects Report #5118167-9
Pamidronate side effect was reported by a Health Professional from UNITED STATES on Sept 22, 2006. Female patient, 40 years of age, was diagnosed with hypercalcaemia, prophylaxis and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: blood pressure increased, blood uric acid increased, caesarean section, dyspnoea, malignant neoplasm progression, normal newborn, platelet count decreased, pleural effusion. Pamidronate dosage: 90 MG, UNK. During the same period patient was treated with MAGNESIUM SULPHATE, BETAMETHASONE. Patient died.

Pamidronate Side Effects Report #5099508-8
Pamidronate side effect was reported by a Health Professional from UNITED STATES on Aug 25, 2006. Female patient, 62 years of age, was diagnosed with breast cancer metastatic and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bacterial infection , bone disorder, bone pain, computerised tomogram abnormal, diarrhoea, hip arthroplasty, malignant neoplasm progression, mouth ulceration, mucosal inflammation. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with GOSERELIN, PROGESTERONE, ANASTROZOLE, FULVESTRANT, AMINOGLUTETHIMIDE, PACLITAXEL, CAPECITABINE. Patient was hospitalized. Patient died on 08/26/2003.

Pamidronate Side Effects Report #4818442-9
Pamidronate side effect was reported by a Health Professional from ITALY on Oct 20, 2005. Female patient, 50 years of age, was diagnosed with breast cancer  and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone disorder, bone pain, malignant neoplasm progression, osteomyelitis, osteonecrosis , periodontal disease, primary sequestrum, sequestrectomy, tooth extraction. Pamidronate dosage: unknown. During the same period patient was treated with ZOLEDRONATE, CYCLOPHOSPHAMIDE. Patient died.


Pamidronate Side Effects Report #4798322-8
Pamidronate side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 01, 2005. Female patient, 77 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone disorder, culture, erythema, local swelling, malignant neoplasm progression, metastasis, osteomyelitis, osteonecrosis , pain . Pamidronate dosage: unknown. Patient died on 08/01/2004.

Pamidronate Side Effects Report #6046589-0
Pamidronate side effect was reported by a Health Professional from CANADA on Jan 12, 2009. Female patient, 70 years of age, was diagnosed with metastases to liver, metastases to bone and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone disorder, buccal mucosal roughening, infection , malignant neoplasm progression, mucosal inflammation, oral surgery, osteonecrosis , swelling face. Pamidronate dosage: 90 MG/MONTH. During the same period patient was treated with FLUOROURACIL, DOCETAXEL, GEMCITABINE, CAPECITABINE. Patient recovered.

Pamidronate Side Effects Report #5020890-1
Pamidronate side effect was reported by a Health Professional from NEW ZEALAND on May 29, 2006. Male patient, 64 years of age, was diagnosed with anaemia and was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone disorder, bone pain, impaired healing, malignant neoplasm progression, osteonecrosis , primary sequestrum, secretion discharge, sinus disorder, tooth abscess. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with BLOOD TRANSFUSION. Patient died on 10/01/2005.

Pamidronate Side Effects Report #4555064-1
Pamidronate side effect was reported by a Physician from on Sept 23, 2004. Female patient, 60 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: biopsy mucosa abnormal, dental caries, impaired healing, inflammation, malignant neoplasm progression, osteonecrosis , tooth extraction, vertebral column mass. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with ZOMETA, THALIDOMIDE, PREDNISONE, ADRIAMYCIN PFS, CYTOXAN, ETOPOSIDE, DEXAMETHASONE, CLINICAL TRIAL WITH BORTEZOMIB. Patient recovered.

Pamidronate Side Effects Report #4668164-2
Pamidronate side effect was reported by a Physician from on Sept 23, 2004. Female patient, 60 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: biopsy mucosa abnormal, dental caries, impaired healing, inflammation, malignant neoplasm progression, osteonecrosis , tooth extraction, vertebral column mass. Pamidronate dosage: 90 MG, QMO. During the same period patient was treated with ZOMETA, THALIDOMIDE, PREDNISONE, ADRIAMYCIN PFS, CYTOXAN, ETOPOSIDE, DEXAMETHASONE, CLINICAL TRIAL WITH BORTEZOMIB. Patient recovered.


Pamidronate Side Effects Report #4555073-2
Pamidronate side effect was reported by a Physician from on Sept 23, 2004. Male patient, 59 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: full blood count decreased, malignant neoplasm progression, osteonecrosis , wound debridement. Pamidronate dosage: unknown. During the same period patient was treated with ZOLEDRONATE, SYNTHROID, VINCRISTINE, CARMUSTINE, CYTOXAN, MELPHALAN, PREDNISONE, INTERFERON. Patient recovered.

Pamidronate Side Effects Report #4668163-0
Pamidronate side effect was reported by a Physician from on Sept 23, 2004. Male patient, 59 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: full blood count decreased, jaw disorder, malignant neoplasm progression, osteonecrosis , wound debridement. Pamidronate dosage: unknown. During the same period patient was treated with ZOLEDRONATE, SYNTHROID, VINCRISTINE, CARMUSTINE, CYTOXAN, MELPHALAN, PREDNISONE. Patient recovered.

Pamidronate Side Effects Report #4555068-9
Pamidronate side effect was reported by a Physician from on Sept 23, 2004. Male patient, 57 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone infection, impaired healing, malignant neoplasm progression, neuropathy, oral soft tissue disorder, osteonecrosis , tooth extraction, wound debridement. Pamidronate dosage: unknown. During the same period patient was treated with PAMIDRONATE DI, ZOLEDRONATE, CYTOXAN, DEXAMETHASONE, ETOPOSIDE, CISPLATIN, CARMUSTINE. Patient recovered.

Pamidronate Side Effects Report #4668157-5
Pamidronate side effect was reported by a Physician from on Sept 23, 2004. Male patient, 57 years of age, was treated with Pamidronate. After drug was administered, patient experienced the following side effects: bone infection, impaired healing, malignant neoplasm progression, neuropathy, oral soft tissue disorder, osteonecrosis , tooth extraction, wound debridement. Pamidronate dosage: unknown. During the same period patient was treated with PAMIDRONATE DI, ZOLEDRONATE, CYTOXAN, DEXAMETHASONE, ETOPOSIDE, CISPLATIN, CARMUSTINE. Patient recovered.