Oxaliplatin and disseminated intravascular coagulation Patient Reports February 12, 2012

Oxaliplatin Side Effects Report #4920544-3
Oxaliplatin side effect was reported by a Health Professional from JAPAN on June 14, 2005. Male patient, 50 years of age, was diagnosed with rectal cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: abscess , bone marrow failure, disease progression, disseminated intravascular coagulation, intestinal obstruction, leukopenia, neutropenia, respiratory failure, thrombocytopenia. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, OXYCONTIN, WHOLE BLOOD. Patient died on 06/30/2005.

Oxaliplatin Side Effects Report #4756753-6
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Aug 29, 2005. Male patient, weighting 97.00 lb, was diagnosed with rectal cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: abnormal behaviour, alanine aminotransferase increased, aspartate aminotransferase increased, blood creatinine increased, cachexia, dialysis , disorientation, disseminated intravascular coagulation, dyspnoea. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, SAXIZON, ALBUMINAR, VENOGLOBULIN, ANTITHROMBIN III, ROCEPHIN, FUTHAN. Patient died on 08/08/2005.

Oxaliplatin Side Effects Report #4850931-3
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Sept 29, 2005. Male patient, weighting 101.4 lb, was diagnosed with rectal cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: abdominal pain , blood urea increased, cardiac arrest , depressed level of consciousness, disseminated intravascular coagulation, enterocolitis haemorrhagic, gastrointestinal haemorrhage, respiratory arrest, septic shock. Oxaliplatin dosage: 120 MG. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, CALCIUM LEVOFOLINATE, FENTANYL. Patient died.

Oxaliplatin Side Effects Report #5500907-8
Oxaliplatin side effect was reported by a Health Professional from UNITED STATES on Oct 24, 2007. Female patient, 45 years of age, weighting 142.0 lb, was diagnosed with non-small cell lung cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: asthenia, disseminated intravascular coagulation, dyspnoea, dysstasia, haemoglobin decreased, platelet count decreased, pneumonia , pyrexia, respiratory failure. Oxaliplatin dosage: 100 MG/M2 (178 MG) EVERY TWO WEEKS. During the same period patient was treated with GEMZAR. Patient was hospitalized. Patient died on 01/17/2006.


Oxaliplatin Side Effects Report #4668664-5
Oxaliplatin side effect was reported by a Health Professional from on Mar 28, 2005. Female patient, weighting 232.6 lb, was diagnosed with non-small cell lung cancer, pain , hypercholesterolaemia, nausea , dyspepsia, hypothyroidism, prophylaxis of nausea and vomiting and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: asthenia, atrial fibrillation , cellulitis , confusional state, dehydration, disseminated intravascular coagulation, hyperkalaemia, hypotension, leukopenia. Oxaliplatin dosage: unknown. During the same period patient was treated with GEMCITABINE, IBUPROFEN, PRAVASTATIN, FAMOTIDINE, LEVOTHYROXINE, ONDANSETRON HYDROCHLORIDE, WARFARIN. Patient was hospitalized. Patient died on 04/22/2005.

Oxaliplatin Side Effects Report #4565126-0
Oxaliplatin side effect was reported by a Physician from on Jan 14, 2005. Male patient, 69 years of age, was diagnosed with metastatic neoplasm and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: anorexia, asthenia, atrial fibrillation , clostridium colitis, disseminated intravascular coagulation, hyperbilirubinaemia, hyperkalaemia, hypoalbuminaemia, hypochloraemia. Oxaliplatin dosage: 110 MG Q2W. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, ENALAPRIL MALEATE, METFORMIN, CEFONICID. Patient was hospitalized. Patient died.

Oxaliplatin Side Effects Report #4864215-0
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Dec 13, 2005. Female patient, 50 years of age, was diagnosed with large intestine carcinoma and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient recovered.

Oxaliplatin Side Effects Report #4880022-7
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Dec 13, 2005. Female patient, weighting 101.4 lb, was diagnosed with large intestine carcinoma and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation. Oxaliplatin dosage: 120 MG/BODY=85.7 MG/M2, INFUSION D1. During the same period patient was treated with FLUOROURACIL, ISOVORIN, NASEA, DECADRON, CALCICOL, MAGNESOL, ASPIRIN. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #4899115-3
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Dec 13, 2005. Female patient, weighting 101.4 lb, was diagnosed with large intestine carcinoma and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, haemoglobin decreased, thrombocytopenia. Oxaliplatin dosage: 120 MG/BODY=85.7 MG/M2, INFUSION D1. During the same period patient was treated with FLUOROURACIL, ISOVORIN, NASEA, DECADRON, CALCICOL, MAGNESOL. Patient was hospitalized. Patient recovered.


Oxaliplatin Side Effects Report #5978416-1
Oxaliplatin side effect was reported by a Physician from HUNGARY on Nov 24, 2008. Male patient, weighting 174.2 lb, was diagnosed with gastric cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, DOCETAXEL. Patient died on 11/19/2008.

Oxaliplatin Side Effects Report #4548654-3
Oxaliplatin side effect was reported by a Physician from on July 02, 2004. Female patient, 76 years of age, was diagnosed with colorectal cancer metastatic and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood lactate dehydrogenase increased, disseminated intravascular coagulation, flank pain, mouth haemorrhage, pain in extremity, protein urine present, pyrexia, red blood cells urine positive. Oxaliplatin dosage: 82 MG/M2 Q2W - INTRAVENOUS NOS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, BEVACIZUMAB, TRIAMTERENE AND HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #4561308-2
Oxaliplatin side effect was reported by a Consumer or non-health professional from on Jan 10, 2005. Male patient, 69 years of age, was diagnosed with colorectal cancer metastatic and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: anorexia, asthenia, atrial fibrillation , blood creatinine increased, disseminated intravascular coagulation, hyperbilirubinaemia, hyperkalaemia, hypoalbuminaemia, hypochloraemia. Oxaliplatin dosage: 110 MG Q2W INTRAVENOUS NOS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN, ENALAPRIL MALEATE, METFORMIN, CEFONICID. Patient was hospitalized. Patient died.

Oxaliplatin Side Effects Report #4739056-5
Oxaliplatin side effect was reported by a Health Professional from THAILAND on Nov 18, 2004. Male patient, weighting 101.4 lb, was diagnosed with colorectal cancer metastatic and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation, febrile neutropenia, hypotension, multi-organ failure, platelet count decreased, prothrombin time prolonged, respiratory failure, septic shock. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN, DEXAMETHASONE. Patient was hospitalized. Patient died on 12/09/2004.

Oxaliplatin Side Effects Report #4999824-1
Oxaliplatin side effect was reported by a Health Professional from THAILAND on Nov 18, 2004. Male patient, weighting 101.4 lb, was diagnosed with colorectal cancer metastatic and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation, febrile neutropenia, hypotension, multi-organ failure, nausea , platelet count decreased, prothrombin level increased, respiratory failure. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN, DEXAMETHASONE. Patient was hospitalized. Patient died on 12/09/2004.


Oxaliplatin Side Effects Report #4708489-5
Oxaliplatin side effect was reported by a Health Professional from JAPAN on May 27, 2005. Female patient, 60 years of age, was diagnosed with colorectal cancer  and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: acidosis, depressed level of consciousness, disseminated intravascular coagulation, ileus, leukopenia, neutropenia, septic shock, thrombocytopenia. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient died on 05/21/2005.

Oxaliplatin Side Effects Report #4592469-7
Oxaliplatin side effect was reported by a Consumer or non-health professional from on Feb 09, 2005. Female patient, 55 years of age, was diagnosed with colorectal cancer  and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: abdominal pain , acidosis, constipation , dehydration, disseminated intravascular coagulation, gastrointestinal neoplasm, herpes zoster, hypotension, ileus. Oxaliplatin dosage: 85 MG/M2 Q2W - INTRAVENOUS NOS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, BEVACIZUMAB SOLUTION. Patient was hospitalized and became disabled. Patient recovered.

Oxaliplatin Side Effects Report #5519682-6
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Nov 07, 2007. Female patient, 65 years of age, was diagnosed with colon cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, febrile neutropenia. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #4715258-9
Oxaliplatin side effect was reported by a Health Professional from JAPAN on July 13, 2005. Female patient, weighting 97.00 lb, was diagnosed with colon cancer, hyperglycaemia, neutropenia and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: blood pressure decreased, diarrhoea, disseminated intravascular coagulation, dyspnoea, hyperglycaemia, hypoxia, leukopenia, malaise, neutropenia. Oxaliplatin dosage: 100MG/BODY=75.2MG/M2 ON DAY 1. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, CALCIUM LEVOFOLINATE, INSULIN, LENOGRASTIM, UNASYN. Patient died on 07/01/2005.

Oxaliplatin Side Effects Report #4724916-1
Oxaliplatin side effect was reported by a Health Professional from JAPAN on June 27, 2005. Male patient was diagnosed with colon cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, cardiac arrest , colon cancer, disseminated intravascular coagulation, haemoglobin decreased, leukopenia, malignant neoplasm progression, nausea . Oxaliplatin dosage: 100MG/BODY, DR. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient died on 06/13/2005.


Oxaliplatin Side Effects Report #4728835-6
Oxaliplatin side effect was reported by a Health Professional from JAPAN on July 13, 2005. Female patient, weighting 97.00 lb, was diagnosed with colon cancer, hyperglycaemia, neutropenia and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: blood pressure decreased, diarrhoea, disseminated intravascular coagulation, dyspnoea, enterobacter infection, hyperglycaemia, leukopenia, malaise, neuropathy peripheral. Oxaliplatin dosage: 100MG/BODY=75.2MG/M2 ON DAY 1. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, CALCIUM LEVOFOLINATE, INSULIN, LENOGRASTIM, UNASYN. Patient died on 07/01/2005.

Oxaliplatin Side Effects Report #4746950-8
Oxaliplatin side effect was reported by a Health Professional from JAPAN on May 18, 2005. Male patient, weighting 97.00 lb, was diagnosed with colon cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: cachexia, colon cancer, disseminated intravascular coagulation, haemoglobin decreased, leukopenia, malignant neoplasm progression, metastases to liver, metastases to lymph nodes, neutropenia. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, IRINOTECAN HYDROCHLORIDE, DOXIFLURIDINE, TEGAFUR, FUROSEMIDE, GRANISETRON. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #4893615-8
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Dec 13, 2005. Male patient, weighting 138.9 lb, was diagnosed with colon cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: ascites, condition aggravated, disseminated intravascular coagulation, haemoglobin decreased, thrombocytopenia. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #4965692-7
Oxaliplatin side effect was reported by a Health Professional from JAPAN on Dec 28, 2005. Male patient, weighting 125.7 lb, was diagnosed with colon cancer, neutropenia and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: ascites, blood pressure decreased, cardiac failure, disseminated intravascular coagulation, haemoglobin decreased, hepatic failure, interstitial lung disease, metastases to liver, multi-organ failure. Oxaliplatin dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, LENOGRASTIM. Patient died on 01/29/2006.

Oxaliplatin Side Effects Report #4711551-4
Oxaliplatin side effect was reported by a Health Professional from UNITED STATES on July 08, 2005. Female patient, 55 years of age, weighting 119.0 lb, was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, disseminated intravascular coagulation, pneumococcal infection, septic shock, streptococcal infection . Oxaliplatin dosage: unknown. Patient was hospitalized. Patient recovered.


Oxaliplatin Side Effects Report #4778415-1
Oxaliplatin side effect was reported by a Health Professional from on Sept 20, 2005. Male patient, 54 years of age, was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: diarrhoea, disseminated intravascular coagulation, gastrointestinal haemorrhage, neutropenia, thrombocytopenia. Oxaliplatin dosage: unknown. During the same period patient was treated with CALCIUM LEVOFOLINATE, FLUOROURACIL. Patient died on 09/11/2005.

Oxaliplatin Side Effects Report #4793827-8
Oxaliplatin side effect was reported by a Health Professional from on Sept 20, 2005. Male patient, 54 years of age, weighting 165.3 lb, was diagnosed with rectal cancer and was treated with Oxaliplatin. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, diarrhoea, disseminated intravascular coagulation, gastrointestinal haemorrhage, haemoglobin decreased, leukopenia, neutropenia, pyrexia, shock. Oxaliplatin dosage: 150MG/BODY=81.1 MG/M2, DR. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE, KYTRIL, DECADRON, CONCENTRATED RED CELLS, CONCENTRATED RED CELLS. Patient died on 09/11/2005.