Orfadin and liver transplant Patient Reports February 12, 2012

Orfadin Side Effects Report #5491395-9
Orfadin side effect was reported by a Health Professional from NORWAY on Oct 03, 2007. Male patient, child 9 years of age, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: hepatic neoplasm malignant, liver transplant . Orfadin dosage: 22 MILLIGRAM TWICE DAILY. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5584949-2
Orfadin side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 19, 2007. Male patient, child 8 years of age, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: developmental delay, liver transplant . Orfadin dosage: 30 MILLIGRAM A DAY. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5605148-1
Orfadin side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 07, 2008. Male patient, child 8 years of age, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: developmental delay, liver transplant , porphyria. Orfadin dosage: 30 MILLIGRAM A DAY. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5707696-2
Orfadin side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 31, 2008. Male patient, child 7 years of age, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: abnormal behaviour, anger, appendicitis , developmental delay, educational problem, encopresis, faecal incontinence, liver transplant , neuropathy peripheral. Orfadin dosage: 30 MG, ORAL. Patient was hospitalized and became disabled. Patient recovered.


Orfadin Side Effects Report #5327561-2
Orfadin side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 11, 2006. Male patient, child 6 years of age, weighting 1.00 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: liver transplant . Orfadin dosage: 10 MILLIGRAM TWICE DAILY. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5327630-7
Orfadin side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 22, 2006. Male patient, child 6 years of age, weighting 1.00 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: liver transplant . Orfadin dosage: 10 MILLIGRAM DAILY ORAL. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5939466-4
Orfadin side effect was reported by a Consumer or non-health professional from on July 08, 2005. Female patient, child 3 years of age, weighting 31.09 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: alpha 1 foetoprotein increased, hepatic cirrhosis, liver transplant . Orfadin dosage: 15 MG, 1 IN 1 D, ORAL. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5106195-9
Orfadin side effect was reported by a Health Professional from AUSTRIA on Aug 21, 2006. Male patient was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: alpha 1 foetoprotein increased, aspiration, cardio-respiratory arrest, dry skin, hepatic failure, liver transplant , loss of consciousness, lymphoma , pruritus. Orfadin dosage: 0.5-1.5 MG/KG MG/KG/DAY, ORAL. Patient recovered.

Orfadin Side Effects Report #5874629-8
Orfadin side effect was reported by a Consumer or non-health professional from on Aug 15, 2008. Male patient, weighting 24.25 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: haemoglobin decreased, hepatic failure, liver transplant , lymphoma , no therapeutic response, renal failure. Orfadin dosage: unknown. Patient was hospitalized. Patient recovered.


Orfadin Side Effects Report #5957339-8
Orfadin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 28, 2008. Male patient, weighting 14.55 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: hepatic cirrhosis, hepatic failure, hepatic neoplasm, liver transplant . Orfadin dosage: 4 MG, ORAL. During the same period patient was treated with CALCIUM SANDOZ, VITAMIN A, VITAMIN K, SPIRONOLACTONE. Patient recovered.

Orfadin Side Effects Report #4989160-1
Orfadin side effect was reported by a Health Professional from UNITED STATES on Feb 18, 2005. Male patient, weighting 1.00 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: liver transplant . Orfadin dosage: 2 MILLIGRAM TWICE DAILY ORAL. Patient recovered.

Orfadin Side Effects Report #4989164-9
Orfadin side effect was reported by a Physician from UNITED STATES on Feb 16, 2005. Male patient, weighting 1.00 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: liver transplant . Orfadin dosage: 5 MILLIGRAM TWICE DAILY ORAL. Patient recovered.