Orfadin and hepatic cirrhosis Patient Reports February 12, 2012

Orfadin Side Effects Report #5939466-4
Orfadin side effect was reported by a Consumer or non-health professional from on July 08, 2005. Female patient, child 3 years of age, weighting 31.09 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: alpha 1 foetoprotein increased, hepatic cirrhosis, liver transplant . Orfadin dosage: 15 MG, 1 IN 1 D, ORAL. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5836100-9
Orfadin side effect was reported by a Physician from GERMANY on July 22, 2008. Male patient, weighting 35.27 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: hepatic cirrhosis, renal impairment. Orfadin dosage: 21MG TDD, 1,35 MG/KG/DAY, ORAL. Patient recovered.

Orfadin Side Effects Report #5874622-5
Orfadin side effect was reported by a Consumer or non-health professional from on Aug 18, 2008. Male patient, weighting 35.27 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: gastric varices, hepatic cirrhosis, renal impairment. Orfadin dosage: 21MG TDD, 1, 35 MG/KG/DAY, ORAL. Patient recovered.

Orfadin Side Effects Report #5957339-8
Orfadin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 28, 2008. Male patient, weighting 14.55 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: hepatic cirrhosis, hepatic failure, hepatic neoplasm, liver transplant . Orfadin dosage: 4 MG, ORAL. During the same period patient was treated with CALCIUM SANDOZ, VITAMIN A, VITAMIN K, SPIRONOLACTONE. Patient recovered.