Orfadin and ascites Patient Reports February 12, 2012

Orfadin Side Effects Report #5927712-2
Orfadin side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 20, 2003. Female patient, child 1 years of age, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: abdominal distension, ascites, eyelid oedema, peritonitis bacterial, pyrexia. Orfadin dosage: 10 MG, 2 IN 1 D, ORAL. During the same period patient was treated with NAHC, CIPRO, ACTIGALL, LASIX, ALDACTONE, PREVACID, MAGNESIUM OXIDE. Patient recovered.

Orfadin Side Effects Report #5081655-8
Orfadin side effect was reported by a Consumer or non-health professional from FRANCE on July 21, 2006. Male patient was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: ascites, haemoglobin decreased, neutropenia, purpura, pyrexia, thrombocytopenia. Orfadin dosage: 0.5 MG/KG TWICE DAILY ORAL. During the same period patient was treated with LASILIX, ALDACTONE, PHOSPHORE, CALCIUM SUPP, DOLIPRANE. Patient recovered.

Orfadin Side Effects Report #5683820-5
Orfadin side effect was reported by a Health Professional from KOREA, REPUBLIC OF on Mar 11, 2008. Female patient, weighting 14.33 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: ascites, disseminated intravascular coagulation, gastrointestinal haemorrhage, hypoalbuminaemia, hypovolaemic shock, peritonitis bacterial, sepsis . Orfadin dosage: 8 MILLIGRAM A DAY ORAL. During the same period patient was treated with AMPICILLIN, FUROSEMIDE, CEFOTAXIME. Patient died.

Orfadin Side Effects Report #4755113-1
Orfadin side effect was reported by a Physician from FRANCE on Aug 10, 2005. Male patient, weighting 1.00 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: ascites, haemoglobin decreased, neutropenia, pyrexia, thrombocytopenia. Orfadin dosage: 0.5 MG/KG TWICE DAILY ORAL. During the same period patient was treated with LASILIX, ALDACTONE, PHOSPHORE, DOLIPRANE. Patient recovered.