Orfadin and alpha 1 foetoprotein increased Patient Reports February 12, 2012

Orfadin Side Effects Report #5939466-4
Orfadin side effect was reported by a Consumer or non-health professional from on July 08, 2005. Female patient, child 3 years of age, weighting 31.09 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: alpha 1 foetoprotein increased, hepatic cirrhosis, liver transplant . Orfadin dosage: 15 MG, 1 IN 1 D, ORAL. Patient was hospitalized. Patient recovered.

Orfadin Side Effects Report #5955201-8
Orfadin side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 28, 2008. Female patient, child 1 years of age, weighting 26.57 lb, was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: alpha 1 foetoprotein increased, hepatic cyst. Orfadin dosage: 12 MG, ORAL. Patient recovered.

Orfadin Side Effects Report #5106195-9
Orfadin side effect was reported by a Health Professional from AUSTRIA on Aug 21, 2006. Male patient was diagnosed with tyrosinaemia and was treated with Orfadin. After drug was administered, patient experienced the following side effects: alpha 1 foetoprotein increased, aspiration, cardio-respiratory arrest, dry skin, hepatic failure, liver transplant , loss of consciousness, lymphoma , pruritus. Orfadin dosage: 0.5-1.5 MG/KG MG/KG/DAY, ORAL. Patient recovered.