Oncaspar and hepatic failure Patient Reports February 11, 2012

Oncaspar Side Effects Report #5713592-7
Oncaspar side effect was reported by a Physician from UNITED STATES on Oct 04, 2007. Male patient, 74 years of age, was diagnosed with colon cancer metastatic and was treated with Oncaspar. After drug was administered, patient experienced the following side effects: cholestasis, constipation , disease progression, fall , head injury, hepatic failure, limb injury, metastases to liver, refusal of treatment by patient. Oncaspar dosage: unknown. During the same period patient was treated with OXYCODONE, PROCHLORPERAZINE, LYRICA, ACETAMINOPHEN AND HYDROCODONE BITARTRATE, ONDANSETRON, ATIVAN. Patient was hospitalized. Patient died on 09/25/2007.

Oncaspar Side Effects Report #5853242-2
Oncaspar side effect was reported by a Physician from UNITED STATES on Aug 06, 2008. Male patient, 41 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Oncaspar. After drug was administered, patient experienced the following side effects: bilirubin conjugated increased, caecitis, confusional state, gastrointestinal motility disorder, hepatic failure, hypotension, impaired gastric emptying, mental status changes, metabolic encephalopathy. Oncaspar dosage: unknown. During the same period patient was treated with VALSARTAN, GLEEVEC, PREDNISONE, INSULIN, ACYCLOVIR, COUMADIN, PRILOSEC. Patient was hospitalized. Patient died.

Oncaspar Side Effects Report #4801754-2
Oncaspar side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 26, 2005. Female patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Oncaspar. After drug was administered, patient experienced the following side effects: cerebrovascular accident, hepatic failure, pancreatitis. Oncaspar dosage: unknown. Patient died.

Oncaspar Side Effects Report #4807413-4
Oncaspar side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 26, 2005. Female patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Oncaspar. After drug was administered, patient experienced the following side effects: cerebrovascular accident, hepatic failure, pancreatitis. Oncaspar dosage: unknown. Patient died.


Oncaspar Side Effects Report #6132490-0
Oncaspar side effect was reported by a Physician from CANADA on Mar 10, 2009. Female patient, 18 years of age, was treated with Oncaspar. After drug was administered, patient experienced the following side effects: abdominal pain , blood pressure decreased, haemorrhage, hepatic failure, hepatomegaly, hypotension, renal failure, weight increased. Oncaspar dosage: unknown. Patient recovered.

Oncaspar Side Effects Report #5942765-3
Oncaspar side effect was reported by a Pharmacist from UNITED STATES on Oct 22, 2008. Male patient, 17 years of age, was treated with Oncaspar. After drug was administered, patient experienced the following side effects: hepatic failure. Oncaspar dosage: unknown. Patient recovered.

Oncaspar Side Effects Report #6132488-2
Oncaspar side effect was reported by a Physician from CANADA on Mar 10, 2009. Female patient, child 12 years of age, was treated with Oncaspar. After drug was administered, patient experienced the following side effects: hepatic failure, hepatobiliary disease, infection . Oncaspar dosage: unknown. Patient died.