Novantrone and mitral valve incompetence Patient Reports February 11, 2012

Novantrone Side Effects Report #6089775-6
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 08, 2009. Male patient, 87 years of age, weighting 163.0 lb, was diagnosed with prostate cancer  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: acute respiratory failure, bundle branch block right, confusional state, mitral valve incompetence, multi-organ failure, neutropenia, pleural effusion, pneumonia , septic shock. Novantrone dosage: 22 MG, 1 IN 3 WEEKS, INTRAVENOUS. During the same period patient was treated with CETUXIMAB, REMERON, ZOCOR, ASPIRIN, TENORMIN, LUPRON, VITAMIN, SELENIUM. Patient was hospitalized. Patient died on 01/05/2009.

Novantrone Side Effects Report #4740954-7
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on July 12, 2005. Female patient, 66 years of age, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: chest pain , dyspnoea, ejection fraction decreased, endocarditis , mitral valve incompetence, pulmonary hypertension . Novantrone dosage: unknown. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #4757919-1
Novantrone side effect was reported by a Physician from UNITED STATES on Aug 16, 2005. Female patient, 66 years of age, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: cardiac failure, chest pain , dyspnoea, ejection fraction decreased, endocarditis , mitral valve incompetence, pulmonary hypertension . Novantrone dosage: unknown. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5475309-3
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 14, 2007. Female patient, 58 years of age, weighting 154.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, cardiomyopathy , dilatation ventricular, left ventricular hypertrophy, mitral valve incompetence, tricuspid valve incompetence, viral infection . Novantrone dosage: unknown. During the same period patient was treated with REBIF. Patient was hospitalized. Patient recovered.


Novantrone Side Effects Report #5041074-7
Novantrone side effect was reported by a Health Professional from UNITED STATES on June 13, 2006. Female patient, 56 years of age, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: atrial fibrillation , atrial pressure increased, cardiac disorder, cardiac failure congestive, cardiomyopathy , mitral valve incompetence, pleural effusion, pulmonary hypertension . Novantrone dosage: 12 MG/M2, INTRAVENOUS. During the same period patient was treated with COPAXONE. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #4819566-2
Novantrone side effect was reported by a Health Professional from UNITED STATES on Oct 14, 2005. Male patient, 52 years of age, weighting 182.1 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiomyopathy , dilatation ventricular, ejection fraction decreased, electrocardiogram st-t change, mitral valve incompetence, sinus tachycardia, tricuspid valve incompetence, troponin increased. Novantrone dosage: unknown. During the same period patient was treated with INTERFERON BETA, MORNIFLUMATE, BACLOFEN, AMANTADINE, NITROFURANTOIN, NORTRIPTYLINE, OXYBUTYNIN HYDROCHLORIDE, ASPIRIN. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #4969273-0
Novantrone side effect was reported by a Health Professional from UNITED STATES on Mar 24, 2006. Male patient, 52 years of age, weighting 182.1 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiomyopathy , dilatation ventricular, ejection fraction decreased, electrocardiogram st-t change, mitral valve incompetence, sinus tachycardia, tricuspid valve incompetence, troponin increased. Novantrone dosage: unknown. During the same period patient was treated with INTERFERON BETA, MORNIFLUMATE, BACLOFEN, AMANTADINE, NITROFURANTOIN, NORTRIPTYLINE, OXYBUTYNIN HYDROCHLORIDE, ASPIRIN. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5029345-1
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on May 31, 2006. Male patient, 52 years of age, weighting 182.1 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiomyopathy , dilatation ventricular, electrocardiogram st-t change, mitral valve incompetence, sinus tachycardia, tricuspid valve incompetence, troponin increased, white blood cell count decreased. Novantrone dosage: unknown. During the same period patient was treated with INTERFERON BETA, MORNIFLUMATE, BACLOFEN, AMANTADINE, NITROFURANTOIN, NORTRIPTYLINE, OXYBUTYNI NHYDROCHLORIDE, ACETYLSALICYLIC ACID SRT. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5778972-2
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 04, 2008. Female patient, 46 years of age, was diagnosed with multiple sclerosis , secondary progressive multiple sclerosis and was treated with Novantrone. After drug was administered, patient experienced the following side effects: asthenia, blood pressure increased, bone pain, ejection fraction decreased, fatigue, mitral valve incompetence, multiple sclerosis relapse, muscle tightness, nausea . Novantrone dosage: unknown. During the same period patient was treated with BETASERON, PROVIGIL, CYMBALTA, CELEXA, ORTHO. Patient recovered.


Novantrone Side Effects Report #4620823-3
Novantrone side effect was reported by a Health Professional from on Mar 11, 2005. Female patient, 46 years of age, weighting 100.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: asthenia, chest discomfort, ejection fraction decreased, mitral valve incompetence, mitral valve prolapse, tricuspid valve incompetence, ventricular dysfunction, ventricular hypertrophy, ventricular hypokinesia. Novantrone dosage: 12 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS (NOT OTHERWISE SPECIFIED). During the same period patient was treated with AMANTADINE, TRIMETHOPRIM. Patient recovered.

Novantrone Side Effects Report #4664157-X
Novantrone side effect was reported by a Health Professional from on May 03, 2005. Female patient, 46 years of age, weighting 100.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: cardiac disorder, dilatation ventricular, ejection fraction decreased, hyperkinesia, mitral valve incompetence, multiple gated acquisition scan abnormal, tricuspid valve incompetence, ventricular dysfunction. Novantrone dosage: 12 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS. During the same period patient was treated with AMANTADINE, TRIMETHOPRIM. Patient recovered.

Novantrone Side Effects Report #4890776-1
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 05, 2006. Female patient, 46 years of age, weighting 100.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac failure congestive, cardiomyopathy , condition aggravated, cough, dilatation ventricular, hyperkinesia, mitral valve incompetence, mitral valve prolapse. Novantrone dosage: unknown. During the same period patient was treated with AMANTADINE. Patient was hospitalized and became disabled. Patient recovered.

Novantrone Side Effects Report #4963166-0
Novantrone side effect was reported by a Health Professional from UNITED STATES on Mar 22, 2006. Female patient, 46 years of age, weighting 100.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, cardiomyopathy , condition aggravated, mitral valve incompetence, mitral valve prolapse, pulmonary hypertension , tricuspid valve incompetence, urinary tract infection , urine leukocyte esterase positive. Novantrone dosage: unknown. During the same period patient was treated with AMANTADINE. Patient was hospitalized and became disabled. Patient died on 03/18/2006.

Novantrone Side Effects Report #6127286-X
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 05, 2009. Female patient, 45 years of age, weighting 114.6 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: cardiomyopathy , mitral valve incompetence, myocardial infarction. Novantrone dosage: unknown. During the same period patient was treated with CYMBALTA, STEROIDS, TOPAMAX, NEURONTIN, PROVIGIL. Patient recovered.


Novantrone Side Effects Report #4747763-3
Novantrone side effect was reported by a Health Professional from UNITED STATES on July 29, 2005. Female patient, 45 years of age, weighting 174.2 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: cardiac failure congestive, cardiac murmur, cardiomegaly, cardiomyopathy , cystitis, dysuria, mitral valve incompetence, post procedural complication, pulmonary hypertension . Novantrone dosage: 12 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS (NOT OTHERWISE SPECIFIED). During the same period patient was treated with SIMVASTATIN, VENLAFAXINE, TRAZODONE, CLONAZEPAM, LEVOTHYROXINE, ESTRADIOL, GABAPENTIN, SERETIDE. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5133747-2
Novantrone side effect was reported by a Physician from UNITED STATES on Oct 05, 2006. Female patient, 38 years of age, weighting 104.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac failure, cardiac failure congestive, cardiomyopathy , dilatation atrial, ejection fraction decreased, malignant melanoma, mitral valve incompetence, peritoneal dialysis. Novantrone dosage: 10 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS. During the same period patient was treated with REBIF. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5192295-4
Novantrone side effect was reported by a Physician from UNITED STATES on Dec 13, 2006. Female patient, 38 years of age, weighting 104.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac failure, cardiomyopathy , dilatation atrial, malignant melanoma, mitral valve incompetence, peritoneal dialysis, pulmonary hypertension , renal failure. Novantrone dosage: 10 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS. During the same period patient was treated with REBIF. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5654451-8
Novantrone side effect was reported by a Physician from UNITED STATES on Feb 21, 2008. Female patient, 35 years of age, weighting 104.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac arrest , cardiac failure, cardiomyopathy , influenza, left atrial dilatation, malignant melanoma, mitral valve incompetence, peritoneal dialysis. Novantrone dosage: 10 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS. During the same period patient was treated with REBIF. Patient was hospitalized. Patient recovered.

Novantrone Side Effects Report #5955633-8
Novantrone side effect was reported by a Physician from UNITED STATES on Nov 05, 2008. Female patient, 35 years of age, weighting 104.0 lb, was diagnosed with multiple sclerosis  and was treated with Novantrone. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac arrest , cardiac failure congestive, cardiomyopathy , influenza, left atrial dilatation, malignant melanoma, mitral valve incompetence, peritoneal dialysis. Novantrone dosage: 10 MG/M2, 1 IN 3 MONTHS, INTRAVENOUS. During the same period patient was treated with REBIF. Patient was hospitalized. Patient died on 02/14/2008.


Novantrone Side Effects Report #5143535-9
Novantrone side effect was reported by a Consumer or non-health professional from UNITED STATES on July 31, 2006. Female patient, 55 years of age, weighting 125.7 lb, was treated with Novantrone. After drug was administered, patient experienced the following side effects: asthenia, cardiomyopathy , chest pain , deep vein thrombosis , dilatation ventricular, ejection fraction decreased, fatigue, mitral valve incompetence, pulmonary embolism . Novantrone dosage: unknown. During the same period patient was treated with INTERFERON BETA, METOPROLOL SUCCINATE, LISINOPRIL, METHOTREXATE, METHYLPREDNISOLONE, BETASERON. Patient was hospitalized and became disabled. Patient recovered.

Novantrone Side Effects Report #5176770-4
Novantrone side effect was reported by a Health Professional from UNITED STATES on Nov 21, 2006. Female patient, 55 years of age, weighting 125.7 lb, was treated with Novantrone. After drug was administered, patient experienced the following side effects: bundle branch block, cardiomyopathy , deep vein thrombosis , dilatation atrial, dilatation ventricular, mitral valve incompetence, pulmonary embolism , tricuspid valve incompetence, ventricular dysfunction. Novantrone dosage: unknown. During the same period patient was treated with INTERFERON BETA, METOPROLOL SUCCINATE, LISINOPRIL. Patient was hospitalized and became disabled. Patient recovered.