Nitisinone and hepatic failure Patient Reports February 11, 2012

Nitisinone Side Effects Report #5382953-0
Nitisinone side effect was reported by a Consumer or non-health professional from SAUDI ARABIA on May 28, 2007. Female patient, child 3 years of age, was diagnosed with tyrosinaemia and was treated with Nitisinone. After drug was administered, patient experienced the following side effects: hepatic failure, hypoglycaemia, hypoxia, ischaemia, septic shock. Nitisinone dosage: 10 MILLIGRAM A DAY ORAL. Patient died.

Nitisinone Side Effects Report #5356685-9
Nitisinone side effect was reported by a Physician from SAUDI ARABIA on May 28, 2007. Female patient was diagnosed with tyrosinaemia and was treated with Nitisinone. After drug was administered, patient experienced the following side effects: cerebral ischaemia, hepatic failure, hypoglycaemia, hypoxic encephalopathy, septic shock. Nitisinone dosage: 10 MILLIGRAM A DAY ORAL. Patient died.

Nitisinone Side Effects Report #5073822-4
Nitisinone side effect was reported by a Health Professional from CHILE on July 13, 2006. Male patient was diagnosed with tyrosinaemia and was treated with Nitisinone. After drug was administered, patient experienced the following side effects: hepatic failure. Nitisinone dosage: 1 MG/KG MG/KG/DAY, ORAL. Patient died.

Nitisinone Side Effects Report #5092686-6
Nitisinone side effect was reported by a Consumer or non-health professional from TURKEY on Aug 09, 2006. Male patient, child 1 years of age, weighting 7.94 lb, was diagnosed with amino acid metabolism disorder and was treated with Nitisinone. After drug was administered, patient experienced the following side effects: hepatic failure. Nitisinone dosage: 1 MG/KG MG/KG/DAY. Patient died.