Nilotinib and diarrhoea Patient Reports February 11, 2012

Nilotinib Side Effects Report #5518989-6
Nilotinib side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Nov 08, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour, insomnia, pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , acinetobacter bacteraemia, constipation , decreased appetite, diarrhoea, dyspnoea, faecal volume decreased. Nilotinib dosage: 800MG DAILY. During the same period patient was treated with ZOPICLONE, FENTANYL, MORPHINE, LORAZEPAM, RIVOTRIL, GABAPENTIN. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5541515-2
Nilotinib side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Nov 29, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour, insomnia, pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , acinetobacter bacteraemia, decreased appetite, diarrhoea, dyspnoea, faecal volume decreased, ileus. Nilotinib dosage: 800MG DAILY. During the same period patient was treated with ZOPICLONE, FENTANYL, MORPHINE, LORAZEPAM, RIVOTRIL, GABAPENTIN. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5567835-3
Nilotinib side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Dec 10, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour, insomnia, pain , urinary incontinence  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , acinetobacter bacteraemia, blood pressure decreased, decreased appetite, diarrhoea, dyspnoea, faecal volume decreased. Nilotinib dosage: 800MG DAILY. During the same period patient was treated with NILOTINIB VS IMATINIB, NILOTINIB VS IMATINIB, ZOPICLONE, FENTANYL, MORPHINE, LORAZEPAM, RIVOTRIL, GABAPENTIN. Patient was hospitalized. Patient died on 12/09/2007.

Nilotinib Side Effects Report #5598104-3
Nilotinib side effect was reported by a Physician from UNITED STATES on Jan 11, 2008. Female patient, 53 years of age, weighting 205.3 lb, was diagnosed with gastrointestinal stromal tumour, diarrhoea, pulmonary embolism  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, hypotension, syncope. Nilotinib dosage: 400 MG, BID. During the same period patient was treated with IMODIUM, LASIX, LOVENOX. Patient was hospitalized. Patient recovered.


Nilotinib Side Effects Report #5607529-9
Nilotinib side effect was reported by a Physician from UNITED STATES on Jan 22, 2008. Female patient, 53 years of age, weighting 205.3 lb, was diagnosed with gastrointestinal stromal tumour, diarrhoea, pulmonary embolism , pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , dehydration, diarrhoea, gastrointestinal tube insertion, hypotension, intestinal obstruction, malignant neoplasm progression, syncope. Nilotinib dosage: 400 MG, BID. During the same period patient was treated with IMODIUM, LASIX, LOVENOX, MORPHINE. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5710675-2
Nilotinib side effect was reported by a Physician from FINLAND on Apr 07, 2008. Male patient, 73 years of age, weighting 164.2 lb, was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: diarrhoea, infection , neutrophil count decreased, pyrexia. Nilotinib dosage: 400 MG, QD. During the same period patient was treated with HYDREA. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5724744-4
Nilotinib side effect was reported by a Physician from FINLAND on Apr 22, 2008. Male patient, 73 years of age, weighting 164.2 lb, was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: diarrhoea, infection , leukopenia, neutrophil count decreased, pyrexia. Nilotinib dosage: 400 MG, QD. During the same period patient was treated with HYDREA. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #6039277-8
Nilotinib side effect was reported by a Physician from UNITED KINGDOM on Jan 13, 2009. Male patient was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: blast cell count increased, blood creatinine increased, blood urea increased, c-reactive protein increased, chest x-ray abnormal, diarrhoea, disease progression, dyspnoea, nausea . Nilotinib dosage: 800 MG, QD. Patient died.

Nilotinib Side Effects Report #5867131-0
Nilotinib side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 28, 2008. Male patient, weighting 194.9 lb, was diagnosed with b-cell type acute leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , diarrhoea, electrocardiogram qt interval abnormal, electrocardiogram qt prolonged, rash . Nilotinib dosage: 400MG BID PO. During the same period patient was treated with VORICONAZOLE, LEVOFLOXACIN, NORVASC, MORPHINE, FILGRASTIM. Patient was hospitalized. Patient recovered.


Nilotinib Side Effects Report #5776289-3
Nilotinib side effect was reported by a Pharmacist from UNITED STATES on June 17, 2008. Male patient, weighting 194.9 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , diarrhoea, electrocardiogram qt prolonged. Nilotinib dosage: 400MG PO BID. During the same period patient was treated with VORICONAZOLE, NORVASC, LEVOFLOXACIN, MORPHINE, FILGRASTIM. Patient recovered.