Nilotinib and dehydration Patient Reports February 11, 2012

Nilotinib Side Effects Report #5598104-3
Nilotinib side effect was reported by a Physician from UNITED STATES on Jan 11, 2008. Female patient, 53 years of age, weighting 205.3 lb, was diagnosed with gastrointestinal stromal tumour, diarrhoea, pulmonary embolism  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, hypotension, syncope. Nilotinib dosage: 400 MG, BID. During the same period patient was treated with IMODIUM, LASIX, LOVENOX. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5607529-9
Nilotinib side effect was reported by a Physician from UNITED STATES on Jan 22, 2008. Female patient, 53 years of age, weighting 205.3 lb, was diagnosed with gastrointestinal stromal tumour, diarrhoea, pulmonary embolism , pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , dehydration, diarrhoea, gastrointestinal tube insertion, hypotension, intestinal obstruction, malignant neoplasm progression, syncope. Nilotinib dosage: 400 MG, BID. During the same period patient was treated with IMODIUM, LASIX, LOVENOX, MORPHINE. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5682312-7
Nilotinib side effect was reported by a Physician from UNITED STATES on Mar 21, 2008. Female patient, 36 years of age, weighting 170.4 lb, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , ascites, blood creatinine increased, constipation , dehydration, gastrointestinal tube insertion, hypotension. Nilotinib dosage: 400 MG, BID. Patient was hospitalized. Patient died on 03/12/2008.