Nilotinib and abdominal pain Patient Reports February 11, 2012

Nilotinib Side Effects Report #5746331-4
Nilotinib side effect was reported by a Physician from FRANCE on May 14, 2008. Male patient, 78 years of age, weighting 180.8 lb, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, asthenia, constipation , gastrointestinal toxicity, subileus. Nilotinib dosage: 800 MG,. During the same period patient was treated with NILOTINIB VS IMATINIB, ALFUZOSIN, DEBRIDAT. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5597232-6
Nilotinib side effect was reported by a Physician from SPAIN on Jan 16, 2008. Male patient, 70 years of age, weighting 132.3 lb, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , anorexia, cardiac failure, concomitant disease progression, fatigue, hepatic failure, malignant neoplasm progression, mental status changes. Nilotinib dosage: 800 MG, QD. During the same period patient was treated with FUROSEMIDE, INSULIN, ASPIRIN, SUNITINIB MALATE. Patient was hospitalized. Patient died on 11/08/2007.

Nilotinib Side Effects Report #5640570-9
Nilotinib side effect was reported by a Physician from POLAND on Feb 21, 2008. Female patient, 66 years of age, weighting 163.1 lb, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , ileus, malignant neoplasm progression, nausea , tumour excision, tumour necrosis. Nilotinib dosage: 800MG DAILY. Patient was hospitalized and became disabled. Patient died on 12/15/2007.

Nilotinib Side Effects Report #5518989-6
Nilotinib side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Nov 08, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour, insomnia, pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , acinetobacter bacteraemia, constipation , decreased appetite, diarrhoea, dyspnoea, faecal volume decreased. Nilotinib dosage: 800MG DAILY. During the same period patient was treated with ZOPICLONE, FENTANYL, MORPHINE, LORAZEPAM, RIVOTRIL, GABAPENTIN. Patient was hospitalized. Patient recovered.


Nilotinib Side Effects Report #5541515-2
Nilotinib side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Nov 29, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour, insomnia, pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , acinetobacter bacteraemia, decreased appetite, diarrhoea, dyspnoea, faecal volume decreased, ileus. Nilotinib dosage: 800MG DAILY. During the same period patient was treated with ZOPICLONE, FENTANYL, MORPHINE, LORAZEPAM, RIVOTRIL, GABAPENTIN. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5567835-3
Nilotinib side effect was reported by a Physician from TAIWAN, PROVINCE OF CHINA on Dec 10, 2007. Male patient, 60 years of age, was diagnosed with gastrointestinal stromal tumour, insomnia, pain , urinary incontinence  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , acinetobacter bacteraemia, blood pressure decreased, decreased appetite, diarrhoea, dyspnoea, faecal volume decreased. Nilotinib dosage: 800MG DAILY. During the same period patient was treated with NILOTINIB VS IMATINIB, NILOTINIB VS IMATINIB, ZOPICLONE, FENTANYL, MORPHINE, LORAZEPAM, RIVOTRIL, GABAPENTIN. Patient was hospitalized. Patient died on 12/09/2007.

Nilotinib Side Effects Report #5607529-9
Nilotinib side effect was reported by a Physician from UNITED STATES on Jan 22, 2008. Female patient, 53 years of age, weighting 205.3 lb, was diagnosed with gastrointestinal stromal tumour, diarrhoea, pulmonary embolism , pain  and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , dehydration, diarrhoea, gastrointestinal tube insertion, hypotension, intestinal obstruction, malignant neoplasm progression, syncope. Nilotinib dosage: 400 MG, BID. During the same period patient was treated with IMODIUM, LASIX, LOVENOX, MORPHINE. Patient was hospitalized. Patient recovered.

Nilotinib Side Effects Report #5682312-7
Nilotinib side effect was reported by a Physician from UNITED STATES on Mar 21, 2008. Female patient, 36 years of age, weighting 170.4 lb, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain , ascites, blood creatinine increased, constipation , dehydration, gastrointestinal tube insertion, hypotension. Nilotinib dosage: 400 MG, BID. Patient was hospitalized. Patient died on 03/12/2008.

Nilotinib Side Effects Report #5867131-0
Nilotinib side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 28, 2008. Male patient, weighting 194.9 lb, was diagnosed with b-cell type acute leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , diarrhoea, electrocardiogram qt interval abnormal, electrocardiogram qt prolonged, rash . Nilotinib dosage: 400MG BID PO. During the same period patient was treated with VORICONAZOLE, LEVOFLOXACIN, NORVASC, MORPHINE, FILGRASTIM. Patient was hospitalized. Patient recovered.


Nilotinib Side Effects Report #5776289-3
Nilotinib side effect was reported by a Pharmacist from UNITED STATES on June 17, 2008. Male patient, weighting 194.9 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Nilotinib. After drug was administered, patient experienced the following side effects: abdominal pain , diarrhoea, electrocardiogram qt prolonged. Nilotinib dosage: 400MG PO BID. During the same period patient was treated with VORICONAZOLE, NORVASC, LEVOFLOXACIN, MORPHINE, FILGRASTIM. Patient recovered.