Neostigmine and neuromuscular block prolonged Patient Reports February 12, 2012

Neostigmine Side Effects Report #6036494-8
Neostigmine side effect was reported by a Health Professional from BRAZIL on Dec 24, 2008. Female patient, 61 years of age, weighting 143.3 lb, was diagnosed with rotator cuff repair and was treated with Neostigmine. After drug was administered, patient experienced the following side effects: blood pressure increased, cardiac arrest , heart rate increased, hypercapnia, neuromuscular block prolonged, somnolence. Neostigmine dosage: 42.6 MG/KG; X1; IV. During the same period patient was treated with CLONIDINE, FENTANYL, ROPIVACAINE, PROPOFOL, ROCURONIUM BROMIDE, SEVOFLURANE, DEXAMETHASONE, ONDANSETRON. Patient recovered.

Neostigmine Side Effects Report #5130607-8
Neostigmine side effect was reported by a Pharmacist from UNITED STATES on Oct 18, 2006. Male patient, 72 years of age, weighting 255.7 lb, was diagnosed with neuromuscular blockade reversal and was treated with Neostigmine. After drug was administered, patient experienced the following side effects: neuromuscular block prolonged, paralysis , post procedural complication. Neostigmine dosage: 5MG X 2 -Q1 HR X 2 IV BOLUS. Patient recovered.