Neoral and depressed level of consciousness Patient Reports February 11, 2012

Neoral Side Effects Report #4961718-5
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on Sept 13, 2005. Male patient, 21 years of age, weighting 88.18 lb, was diagnosed with stem cell transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: csf lymphocyte count abnormal, depressed level of consciousness, encephalitis , renal impairment. Neoral dosage: 100 MG/D. During the same period patient was treated with SANDIMMUNE, FLUDARABINE, THIOTEPA, ATGAM, IRRADIATION. Patient died on 09/12/2005.

Neoral Side Effects Report #5115865-8
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on May 08, 2006. Male patient, 64 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: anuria, blood pressure decreased, body temperature decreased, bone marrow failure, c-reactive protein increased, depressed level of consciousness, gastric lavage, haematocrit decreased. Neoral dosage: 1675 MG, ONCE/SINGLE. During the same period patient was treated with CELLCEPT, ARTIST, PROCYLIN, AMLODIN, MUCOSTA. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5119785-4
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on May 08, 2006. Male patient, 64 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: anuria, blood pressure decreased, body temperature decreased, bone marrow failure, c-reactive protein increased, depressed level of consciousness, gastric lavage, haematocrit decreased. Neoral dosage: 1675 MG, ONCE/SINGLE. During the same period patient was treated with CELLCEPT, ARTIST, PROCYLIN, AMLODIN, MUCOSTA. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5017899-0
Neoral side effect was reported by a Pharmacist from JAPAN on May 08, 2006. Male patient, 64 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: anuria, blood pressure decreased, body temperature decreased, bone marrow failure, c-reactive protein increased, depressed level of consciousness, gastric lavage, haematocrit decreased. Neoral dosage: 1675 MG, ONCE/SINGLE. During the same period patient was treated with CELLCEPT, ARTIST, PROCYLIN, AMLODIN, MUCOSTA. Patient was hospitalized. Patient recovered.


Neoral Side Effects Report #5019898-1
Neoral side effect was reported by a Pharmacist from JAPAN on May 08, 2006. Male patient, 64 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: anuria, blood pressure decreased, body temperature decreased, bone marrow failure, c-reactive protein increased, depressed level of consciousness, gastric lavage, haemodialysis. Neoral dosage: 1675 MG, ONCE/SINGLE. During the same period patient was treated with CELLCEPT, ARTIST, PROCYLIN, AMLODIN, MUCOSTA. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5354396-7
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on June 04, 2007. Female patient, 62 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: acalculia, agnosia, agraphia, alexia, aphasia , apraxia, central nervous system necrosis, depressed level of consciousness, dysstasia. Neoral dosage: 5 MG/KG/D. During the same period patient was treated with CELLCEPT, PREDONINE. Patient died on 01/01/2006.

Neoral Side Effects Report #5030035-X
Neoral side effect was reported by a Health Professional from JAPAN on Feb 01, 2006. Male patient, 52 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: abdominal pain lower, anuria, depressed level of consciousness, disseminated intravascular coagulation, escherichia infection, haemodialysis, hepatic failure, hepatitis b , hepatitis b e antigen. Neoral dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISOLONE. Patient was hospitalized. Patient died.

Neoral Side Effects Report #6136725-X
Neoral side effect was reported by a Health Professional from FRANCE on Mar 26, 2009. Male patient, 22 years of age, was diagnosed with renal transplant and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaemia, cerebellar ischaemia, coma, depressed level of consciousness, extrapyramidal disorder, hepatitis c , hyponatraemia, meningism. Neoral dosage: 125 MG, BID. During the same period patient was treated with CELLCEPT, PREDNISOLONE. Patient died.

Neoral Side Effects Report #5202374-0
Neoral side effect was reported by a Physician from JAPAN on Dec 27, 2006. Female patient, child 4 years of age, weighting 39.68 lb, was diagnosed with polyarteritis nodosa and was treated with Neoral. After drug was administered, patient experienced the following side effects: abnormal behaviour, agitation, atrioventricular block second degree, convulsion, depressed level of consciousness, encephalopathy, headache , hypertension. Neoral dosage: 50 MG/D. During the same period patient was treated with PREDONINE. Patient was hospitalized. Patient recovered.


Neoral Side Effects Report #5299380-7
Neoral side effect was reported by a Physician from JAPAN on Apr 05, 2007. Female patient, child 4 years of age, weighting 39.68 lb, was diagnosed with polyarteritis nodosa and was treated with Neoral. After drug was administered, patient experienced the following side effects: abnormal behaviour, agitation, atrioventricular block second degree, convulsion, depressed level of consciousness, encephalopathy, headache , hypertension. Neoral dosage: 50 MG/D. During the same period patient was treated with PREDONINE, HERBESSER. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5874568-2
Neoral side effect was reported by a Physician from JAPAN on Sept 04, 2008. Male patient, 83 years of age, was diagnosed with nephrotic syndrome and was treated with Neoral. After drug was administered, patient experienced the following side effects: cardiac failure, depressed level of consciousness, oliguria, pleural effusion, pulmonary congestion, pulmonary embolism , pyrexia, thrombotic thrombocytopenic purpura. Neoral dosage: 75 MG PER DAY. During the same period patient was treated with DIOVAN, PREDONINE, HUMULIN R, NEOPAREN. Patient died on 08/25/2008.

Neoral Side Effects Report #5394974-2
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on July 17, 2007. Male patient, child 7 years of age, was diagnosed with nephrotic syndrome and was treated with Neoral. After drug was administered, patient experienced the following side effects: brain oedema, depressed level of consciousness, grand mal convulsion, hypertension, hypertensive encephalopathy, reversible posterior leukoencephalopathy syndrome. Neoral dosage: unknown. During the same period patient was treated with NIFEDIPINE, ENALAPRIL MALEATE, STEROIDS NOS. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #4869308-X
Neoral side effect was reported by a Consumer or non-health professional from FRANCE on Dec 27, 2005. Female patient, child 5 years of age, was diagnosed with nephrotic syndrome and was treated with Neoral. After drug was administered, patient experienced the following side effects: accidental overdose, blood magnesium decreased, blood phosphorus decreased, depressed level of consciousness, encephalopathy, hypertension, incorrect dose administered. Neoral dosage: 600 MG, BID. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #4961713-6
Neoral side effect was reported by a Consumer or non-health professional from FRANCE on Dec 27, 2005. Female patient, child 5 years of age, was diagnosed with nephrotic syndrome and was treated with Neoral. After drug was administered, patient experienced the following side effects: accidental overdose, blood magnesium decreased, blood phosphorus decreased, convulsion, depressed level of consciousness, encephalopathy, hypertension. Neoral dosage: 600 MG, BID. Patient was hospitalized. Patient recovered.


Neoral Side Effects Report #5361513-1
Neoral side effect was reported by a Physician from JAPAN on June 07, 2007. Female patient, child 10 years of age, was diagnosed with nephrotic syndrome and was treated with Neoral. After drug was administered, patient experienced the following side effects: convulsion, depressed level of consciousness, disease recurrence, headache , nephrotic syndrome, paralysis , toxic induced encephalopathy. Neoral dosage: unknown. During the same period patient was treated with ADRENOCORTICOTROPHIC HORMONE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5886700-5
Neoral side effect was reported by a Physician from JAPAN on Sept 10, 2008. Male patient, weighting 114.6 lb, was diagnosed with nephrotic syndrome and was treated with Neoral. After drug was administered, patient experienced the following side effects: anuria, blood pressure decreased, cardiac arrest , cardiac failure, chills, depressed level of consciousness, mouth breathing, oliguria. Neoral dosage: 75 MG PER DAY. During the same period patient was treated with PREDONINE, DIOVAN, HUMULIN, NEOPAREN, AMLODIPINE BESYLATE, LEVOTHYROXINE. Patient died on 08/25/2008.

Neoral Side Effects Report #4933532-8
Neoral side effect was reported by a Physician from JAPAN on Feb 28, 2006. Male patient, 58 years of age, was diagnosed with lung transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaemia, blood bilirubin increased, depressed level of consciousness, infection , leukoencephalopathy, renal impairment, sepsis , surgery , thrombocytopenia. Neoral dosage: unknown. During the same period patient was treated with SANDIMMUNE, PROGRAF, CELLCEPT. Patient was hospitalized and became disabled. Patient died on 02/04/2006.

Neoral Side Effects Report #4957808-3
Neoral side effect was reported by a Physician from JAPAN on Feb 28, 2006. Male patient, 58 years of age, was diagnosed with lung transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaemia, blood bilirubin increased, depressed level of consciousness, haemolytic anaemia, infection , leukoencephalopathy, nephropathy toxic, renal impairment, sepsis . Neoral dosage: unknown. During the same period patient was treated with SANDIMMUNE, PROGRAF, CELLCEPT. Patient was hospitalized and became disabled. Patient died on 02/04/2006.

Neoral Side Effects Report #4707071-3
Neoral side effect was reported by a Physician from SPAIN on Nov 18, 2004. Male patient, 39 years of age, weighting 154.3 lb, was diagnosed with liver transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: cholestasis, depressed level of consciousness, disease progression, encephalopathy, graft dysfunction, hepatic enzyme abnormal, korsakoff's psychosis non-alcoholic, lung infiltration, pneumonia aspiration. Neoral dosage: unknown. During the same period patient was treated with SIMULECT. Patient was hospitalized and became disabled. Patient died on 01/10/2005.


Neoral Side Effects Report #5928916-5
Neoral side effect was reported by a Physician from SPAIN on Oct 23, 2008. Male patient, weighting 154.3 lb, was diagnosed with liver transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: aphasia , central pontine myelinolysis, depressed level of consciousness, encephalopathy, hypernatraemia, mobility decreased, neurotoxicity, respiratory disorder. Neoral dosage: unknown. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #4871644-8
Neoral side effect was reported by a Physician from JAPAN on Dec 09, 2005. Female patient was diagnosed with liver transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: blood magnesium abnormal, blood pressure systolic increased, convulsion, depressed level of consciousness, encephalopathy, visual field defect. Neoral dosage: 25 MG, BID. During the same period patient was treated with TACROLIMUS, CELLCEPT, PREDONINE. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5276065-4
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on Mar 14, 2007. Male patient, child 8 years of age, was diagnosed with juvenile arthritis and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaphylactic shock, convulsion, depressed level of consciousness, disease recurrence, headache , hypertension, juvenile arthritis, opisthotonus. Neoral dosage: 100 MG/D. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, DEXAMETHASONE PALMITATE. Patient recovered.

Neoral Side Effects Report #5286012-7
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on Mar 26, 2007. Male patient, child 8 years of age, was diagnosed with juvenile arthritis and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaphylactic shock, convulsion, cyanosis, depressed level of consciousness, disease recurrence, eye disorder, headache , hypertension. Neoral dosage: 100 MG/D. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, DEXAMETHASONE PALMITATE. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #4841834-9
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, child 8 years of age, was diagnosed with juvenile arthritis and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaphylactic shock, convulsion, depressed level of consciousness, disease recurrence, headache , hypertension, reversible posterior leukoencephalopathy syndrome, vomiting. Neoral dosage: unknown. During the same period patient was treated with PREDNISOLONE, METHOTREXATE. Patient recovered.


Neoral Side Effects Report #4847849-9
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, child 8 years of age, was diagnosed with juvenile arthritis and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaphylactic shock, convulsion, depressed level of consciousness, disease recurrence, headache , hypertension, juvenile arthritis, opisthotonus, pain in extremity. Neoral dosage: unknown. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, DEXAMETHASONE PALMITATE. Patient recovered.

Neoral Side Effects Report #4903019-7
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on Nov 02, 2005. Male patient, child 8 years of age, was diagnosed with juvenile arthritis and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaphylactic shock, convulsion, depressed level of consciousness, disease recurrence, headache , hypertension, juvenile arthritis, nuclear magnetic resonance imaging brain abnormal. Neoral dosage: 100 MG/D. During the same period patient was treated with PREDNISOLONE, METHOTREXATE, DEXAMETHASONE PALMITATE. Patient recovered.

Neoral Side Effects Report #6023548-5
Neoral side effect was reported by a Health Professional from JAPAN on Dec 24, 2008. Female patient, weighting 59.52 lb, was diagnosed with henoch-schonlein purpura, abdominal symptom and was treated with Neoral. After drug was administered, patient experienced the following side effects: blepharospasm, cerebral atrophy, convulsion, depressed level of consciousness, epilepsy , eye movement disorder, headache , hemianopia homonymous, hypertensive encephalopathy. Neoral dosage: 100 TO 150 MG/DAY. During the same period patient was treated with STEROIDS NOS, PREDONINE, PERSANTINE, SAIREI, COLONEL. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5324803-4
Neoral side effect was reported by a Physician from JAPAN on May 10, 2007. Male patient, 84 years of age, weighting 114.6 lb, was diagnosed with glomerulonephritis membranous and was treated with Neoral. After drug was administered, patient experienced the following side effects: abnormal behaviour, amnesia, anaemia, decreased appetite, dehydration, dementia , depressed level of consciousness, haematemesis, haematocrit decreased. Neoral dosage: 100 MG/D. During the same period patient was treated with BREDININ, CONIEL, ATELEC, ADALAT, FIRSTCIN, BAKTAR, ASPIRIN. Patient was hospitalized. Patient died on 05/01/2007.

Neoral Side Effects Report #4847835-9
Neoral side effect was reported by a Physician from JAPAN on Oct 28, 2005. Male patient, 72 years of age, weighting 103.6 lb, was diagnosed with erythrodermic psoriasis and was treated with Neoral. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, contusion, depressed level of consciousness, diabetic complication, disease progression, fall , hypercalcaemia, hypoglycaemia. Neoral dosage: 150 MG/EVERY OTHER DAY. During the same period patient was treated with ZYLORIC, BASEN, CELTECT, GLYCYRON, ATARAX, GASTER. Patient was hospitalized. Patient recovered.


Neoral Side Effects Report #4873257-0
Neoral side effect was reported by a Physician from JAPAN on Oct 28, 2005. Male patient, 72 years of age, weighting 103.6 lb, was diagnosed with erythrodermic psoriasis and was treated with Neoral. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, c-reactive protein increased, contusion, depressed level of consciousness, diabetic complication, disease progression, fall , hypercalcaemia. Neoral dosage: 150 MG/EVERY OTHER DAY. During the same period patient was treated with ZYLORIC, BASEN, CELTECT, GLYCYRON, ATARAX. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5083460-5
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on July 14, 2006. Male patient, 20 years of age, was diagnosed with colitis ulcerative and was treated with Neoral. After drug was administered, patient experienced the following side effects: anaemia, back pain , blood pressure decreased, chest pain , coagulation time prolonged, depressed level of consciousness, epistaxis, haematochezia, hepatic enzyme increased. Neoral dosage: 150 MG/D. During the same period patient was treated with ADRENOCORTICOTROPHIC HORMONE, PENTASA. Patient was hospitalized. Patient died on 02/07/2006.

Neoral Side Effects Report #5840642-X
Neoral side effect was reported by a Health Professional from JAPAN on July 30, 2008. Female patient was diagnosed with colitis ulcerative and was treated with Neoral. After drug was administered, patient experienced the following side effects: depressed level of consciousness. Neoral dosage: unknown. During the same period patient was treated with PENTASA, SALAZOPYRIN, PREDNISOLONE. Patient recovered.

Neoral Side Effects Report #5845720-7
Neoral side effect was reported by a Health Professional from JAPAN on Aug 06, 2008. Female patient was diagnosed with colitis ulcerative and was treated with Neoral. After drug was administered, patient experienced the following side effects: depressed level of consciousness. Neoral dosage: unknown. During the same period patient was treated with PENTASA, SALAZOPYRIN, PREDNISOLONE. Patient recovered.

Neoral Side Effects Report #5368246-6
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on June 20, 2007. Male patient, 15 years of age, weighting 72.75 lb, was diagnosed with chronic graft versus host disease and was treated with Neoral. After drug was administered, patient experienced the following side effects: abdominal pain upper, anxiety , blister, c-reactive protein increased, cholecystitis chronic, depressed level of consciousness, disseminated intravascular coagulation, gastritis, haemorrhage. Neoral dosage: 25 MG/D. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYTARABINE, FLUDARABINE, MELPHALAN, TACROLIMUS, METHOTREXATE, PREDNISOLONE, PENTAZOCINE LACTATE. Patient was hospitalized. Patient died on 07/17/2004.


Neoral Side Effects Report #5369976-2
Neoral side effect was reported by a Consumer or non-health professional from JAPAN on June 20, 2007. Male patient, 15 years of age, weighting 72.75 lb, was diagnosed with chronic graft versus host disease and was treated with Neoral. After drug was administered, patient experienced the following side effects: abdominal pain upper, anxiety , blister, c-reactive protein increased, cholecystitis chronic, depressed level of consciousness, disseminated intravascular coagulation, gastritis, haemorrhage. Neoral dosage: 25 MG/D. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYTARABINE, FLUDARABINE PHOSPHATE, MELPHALAN, TACROLIMUS, METHOTREXATE, PREDNISOLONE, PENTAZOCINE LACTATE. Patient was hospitalized. Patient died on 07/17/2004.

Neoral Side Effects Report #5212881-2
Neoral side effect was reported by a Consumer or non-health professional from FRANCE on Jan 15, 2007. Male patient, child 12 years of age, weighting 97.00 lb, was diagnosed with bone marrow transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cerebral disorder, cytolytic hepatitis, delusion, depressed level of consciousness, hallucination, headache , nightmare, photophobia. Neoral dosage: 60 MG, BID. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5175867-2
Neoral side effect was reported by a Consumer or non-health professional from FRANCE on Dec 04, 2006. Male patient, child 12 years of age, weighting 97.00 lb, was diagnosed with bone marrow transplant  and was treated with Neoral. After drug was administered, patient experienced the following side effects: acute graft versus host disease in skin, cerebral disorder, cytolytic hepatitis, delusion, depressed level of consciousness, hallucination, headache , nightmare, photophobia. Neoral dosage: 60 MG, BID. Patient was hospitalized. Patient recovered.

Neoral Side Effects Report #5866485-9
Neoral side effect was reported by a Physician from UNITED STATES on Sept 02, 2008. Male patient, weighting 276.7 lb, was treated with Neoral. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, depressed level of consciousness, impaired healing, pleural effusion, pulmonary oedema, renal failure acute, respiratory disorder, respiratory failure, skin ulcer. Neoral dosage: 200MG PO + 97MG IV. During the same period patient was treated with SANDIMMUNE, CLONIDINE TTS, PREDNISONE, KAYEXALATE, PEPCID, PROCARDIA, LASIX. Patient was hospitalized. Patient recovered.