Neoprofen and intestinal perforation Patient Reports February 13, 2012

Neoprofen Side Effects Report #5759552-1
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on June 04, 2008. Female patient, weighting 1.54 lb, was diagnosed with patent ductus arteriosus repair and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: abdominal abscess, abdominal distension, ileal perforation, intestinal perforation, skin discolouration. Neoprofen dosage: 10MG/KG X 1 042; 5MG/KG Q24HRS X 2 DOSES 042. Patient died on 02/13/2008.

Neoprofen Side Effects Report #5759558-2
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on June 04, 2008. Male patient, weighting 1.43 lb, was diagnosed with patent ductus arteriosus repair and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: anuria, aspiration, blood creatinine decreased, ileal perforation, intestinal perforation, meconium increased, skin discolouration, urine output decreased, waist circumference increased. Neoprofen dosage: 10MG/KG X 1 042; 5MG/KG Q24HRS X 2 DOSES 042. Patient died on 04/23/2008.

Neoprofen Side Effects Report #5157730-6
Neoprofen side effect was reported by a Physician from UNITED STATES on Nov 02, 2006. Female patient, child .0 years of age, was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: intestinal perforation. Neoprofen dosage: 10 MG/KG; 1X; IV; SEE IMAGE. Patient recovered.

Neoprofen Side Effects Report #5302923-8
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on Apr 02, 2007. Male patient, weighting 1.72 lb, was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: abdominal distension, intestinal perforation, necrotising enterocolitis neonatal. Neoprofen dosage: unknown. Patient recovered.


Neoprofen Side Effects Report #5302935-4
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on Apr 02, 2007. Male patient, weighting 1.72 lb, was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: abdominal distension, intestinal perforation, necrotising enterocolitis neonatal. Neoprofen dosage: unknown. Patient recovered.

Neoprofen Side Effects Report #5485612-9
Neoprofen side effect was reported by a Physician from UNITED STATES on Oct 11, 2007. Female patient, weighting 1.26 lb, was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: erythema, fungal infection , intestinal perforation, neutropenia. Neoprofen dosage: 10MG/KG -1ST DOSE- 1 DOSE IV. Patient recovered.

Neoprofen Side Effects Report #5530281-2
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on Nov 27, 2007. Female patient, weighting 1.74 lb, was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: intestinal perforation, sepsis . Neoprofen dosage: 8.57 MG DAILY IV; 3.8 MG DAILY IV. During the same period patient was treated with GENTAMICIN, AMPICILLIN. Patient was hospitalized. Patient recovered.

Neoprofen Side Effects Report #5759557-0
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on June 04, 2008. Male patient, weighting 1.41 lb, was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: intestinal perforation, neonatal hypotension, peritoneal fluid analysis abnormal. Neoprofen dosage: 10MG/KG X1 042; 5MG/KG Q24 HRS X 2 DOSES 042. Patient died on 04/30/2008.

Neoprofen Side Effects Report #5814339-6
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on July 01, 2008. Male patient was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: discomfort, intestinal perforation, neonatal hypotension, sepsis neonatal, urine output decreased. Neoprofen dosage: 10 MG/KG; IV; 5 MG/KG; IV; IV. During the same period patient was treated with FLUCONAZOLE, CAFFEINE, VITAMIN A, DOPAMINE INFUSION, INSULIN, FENTANYL INFUSION, TOTAL PARENTERAL NUTRITION AND LIPID INFUSION. Patient died on 04/23/2008.


Neoprofen Side Effects Report #6094770-7
Neoprofen side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 10, 2009. Female patient was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: gastrointestinal necrosis, intestinal perforation. Neoprofen dosage: unknown. During the same period patient was treated with VANCOMYCIN, CEFOTAXIME, CLINDAMYCIN. Patient recovered.

Neoprofen Side Effects Report #6094771-9
Neoprofen side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 10, 2009. Male patient was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: intestinal perforation, pneumoperitoneum. Neoprofen dosage: unknown. During the same period patient was treated with CEFOTAXIME, VANCOMYCIN. Patient recovered.

Neoprofen Side Effects Report #6121387-8
Neoprofen side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 26, 2009. Female patient was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: gastrointestinal necrosis, intestinal perforation, neonatal disorder. Neoprofen dosage: 10 MG/KG; QD; IV, 5 MG/KG; QD; IV. During the same period patient was treated with VANCOMYCIN, CEFOTAXIME, CLINDAMYCIN. Patient recovered.

Neoprofen Side Effects Report #6121392-1
Neoprofen side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 26, 2009. Male patient was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: intestinal perforation, pneumoperitoneum. Neoprofen dosage: 10 MG/KG; QD; IV, 5 MG/KG; QD; IV. During the same period patient was treated with CEFOTAXIME, VANCOMYCIN. Patient recovered.