Neoprofen and ileal perforation Patient Reports February 12, 2012

Neoprofen Side Effects Report #5759552-1
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on June 04, 2008. Female patient, weighting 1.54 lb, was diagnosed with patent ductus arteriosus repair and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: abdominal abscess, abdominal distension, ileal perforation, intestinal perforation, skin discolouration. Neoprofen dosage: 10MG/KG X 1 042; 5MG/KG Q24HRS X 2 DOSES 042. Patient died on 02/13/2008.

Neoprofen Side Effects Report #5759558-2
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on June 04, 2008. Male patient, weighting 1.43 lb, was diagnosed with patent ductus arteriosus repair and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: anuria, aspiration, blood creatinine decreased, ileal perforation, intestinal perforation, meconium increased, skin discolouration, urine output decreased, waist circumference increased. Neoprofen dosage: 10MG/KG X 1 042; 5MG/KG Q24HRS X 2 DOSES 042. Patient died on 04/23/2008.

Neoprofen Side Effects Report #5656138-4
Neoprofen side effect was reported by a Pharmacist from UNITED STATES on Feb 25, 2008. Female patient was diagnosed with patent ductus arteriosus and was treated with Neoprofen. After drug was administered, patient experienced the following side effects: abdominal abscess, ileal perforation, peritonitis. Neoprofen dosage: 10 MG/KG; QD; IV; 5 MG/KG; QD; IV; 5 MG/KG; QD; IV. During the same period patient was treated with DOPAMINE, HYDROCORTISONE. Patient died on 02/13/2008.