Nelarabine and confusional state Patient Reports February 12, 2012

Nelarabine Side Effects Report #5470544-2
Nelarabine side effect was reported by a Pharmacist from UNITED STATES on Sept 27, 2007. Male patient, weighting 187.4 lb, was diagnosed with t-cell lymphoma refractory and was treated with Nelarabine. After drug was administered, patient experienced the following side effects: aggression, bilirubin conjugated increased, blood bilirubin increased, cerebellar infarction, confusional state, csf white blood cell count positive, disorientation, hepatic enzyme increased, international normalised ratio increased. Nelarabine dosage: 1275 MG DAILY X 5 DAYS IV. During the same period patient was treated with BACTRIM DS, LOVENOX, AMLODIPINE, GRANISETRON, ESOMEPRAZOLE MAGNESIUM, DIPHENHYDRAMINE, MORPHINE, NIFEDIPINE. Patient was hospitalized. Patient recovered.

Nelarabine Side Effects Report #5156314-3
Nelarabine side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 01, 2006. Male patient, 56 years of age, was diagnosed with disease recurrence and was treated with Nelarabine. After drug was administered, patient experienced the following side effects: abnormal behaviour, abulia, confusional state, demyelination, disinhibition, hypomania, progressive multifocal leukoencephalopathy. Nelarabine dosage: unknown. During the same period patient was treated with METHOTREXATE, CYTARABINE, CYCLOPHOSPHAMIDE, DOXORUBICIN HYDROCHLORIDE, DEXAMETHASONE. Patient recovered.