Naglazyme and pulmonary hypertension Patient Reports February 11, 2012

Naglazyme Side Effects Report #5397300-8
Naglazyme side effect was reported by a Health Professional from COLOMBIA on July 06, 2007. Male patient, child 3 years of age, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, cardiac failure congestive, culture positive, pneumonia , pulmonary hypertension , staphylococcal infection . Naglazyme dosage: 10 MG, QW; IV. During the same period patient was treated with BETA, BRONCHLODIALTOR, OXYGEN, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Naglazyme Side Effects Report #5413007-2
Naglazyme side effect was reported by a Health Professional from COLOMBIA on July 25, 2007. Male patient, child 3 years of age, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, cardiac failure congestive, culture positive, oxygen saturation decreased, pneumonia , pulmonary hypertension , respiratory distress, sleep study abnormal. Naglazyme dosage: 10 MG; QW; IV. During the same period patient was treated with BETA, BRONCHODILATOR, OXYGEN, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Naglazyme Side Effects Report #5443298-3
Naglazyme side effect was reported by a Health Professional from COLOMBIA on Aug 15, 2007. Male patient, child 3 years of age, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: acute respiratory failure, alpha haemolytic streptococcal infection, cardiac failure congestive, haemodynamic instability, no therapeutic response, pneumonia , pulmonary hypertension , sleep apnoea syndrome, staphylococcal infection . Naglazyme dosage: 10 MG; QW; IV. During the same period patient was treated with BRONCHODILATOR, OXYGEN, FUROSEMIDE, BETA. Patient was hospitalized. Patient recovered.

Naglazyme Side Effects Report #5946388-1
Naglazyme side effect was reported by a Physician from BRAZIL on Oct 23, 2008. Male patient, 18 years of age, weighting 55.12 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: cardiac failure, condition aggravated, fluid overload, lobar pneumonia, pneumonia bacterial, pulmonary hypertension . Naglazyme dosage: 25 MG;QW;IVDRP. During the same period patient was treated with CETRIRIZINE. Patient was hospitalized. Patient recovered.


Naglazyme Side Effects Report #6123836-8
Naglazyme side effect was reported by a Physician from BRAZIL on Mar 02, 2009. Male patient, 18 years of age, weighting 55.12 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: cardiac failure congestive, condition aggravated, endotracheal intubation complication, incorrect dose administered, lobar pneumonia, pneumonia bacterial, pulmonary hypertension . Naglazyme dosage: 25 MG;QW; IVDRP. During the same period patient was treated with CETIRIZINE. Patient was hospitalized. Patient died on 03/02/2009.

Naglazyme Side Effects Report #5614706-X
Naglazyme side effect was reported by a Health Professional from IRELAND on Jan 16, 2008. Female patient, 13 years of age, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: pneumonia , pulmonary hypertension . Naglazyme dosage: unknown. Patient was hospitalized. Patient recovered.

Naglazyme Side Effects Report #5629947-5
Naglazyme side effect was reported by a Health Professional from IRELAND on Jan 28, 2008. Female patient, 13 years of age, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: cardiac arrest , pneumonia , pulmonary hypertension . Naglazyme dosage: unknown. Patient was hospitalized. Patient died on 01/01/2008.

Naglazyme Side Effects Report #5776618-0
Naglazyme side effect was reported by a Physician from COLOMBIA on June 02, 2008. Male patient, child 12 years of age, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: bronchial obstruction, cardiac failure, cardio-respiratory arrest, cardiomyopathy , disease progression, mucopolysaccharidosis vi, multi-organ failure, pulmonary hypertension , renal failure. Naglazyme dosage: 20 MG; QW; IV. During the same period patient was treated with ALDACTONE, FUROSEMIDE, SILDENAFIL, CARVEDILOL. Patient was hospitalized. Patient died on 04/22/2008.

Naglazyme Side Effects Report #5614708-3
Naglazyme side effect was reported by a Physician from COLOMBIA on Jan 16, 2008. Male patient, child 11 years of age, weighting 39.68 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: pulmonary hypertension , tonsillitis. Naglazyme dosage: unknown. Patient was hospitalized. Patient recovered.


Naglazyme Side Effects Report #5646419-2
Naglazyme side effect was reported by a Physician from IRELAND on Feb 13, 2008. Female patient, child 11 years of age, weighting 44.09 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: aortic valve incompetence, cardiac arrest , mitral valve incompetence, pneumonia , pulmonary haemorrhage, pulmonary hypertension , respiratory tract infection, tricuspid valve incompetence. Naglazyme dosage: 20 MG QW IV. During the same period patient was treated with MEROPENEM, VANCOMYCIN, ERYTHROMYCIN, CIPROFLOXACIN, VORICONAZOLE, MILRINONE LACTATE, FUROSEMIDE, MORPHINE. Patient was hospitalized. Patient died on 01/25/2008.