Naglazyme and oxygen saturation decreased Patient Reports February 11, 2012

Naglazyme Side Effects Report #5663681-0
Naglazyme side effect was reported by a Physician from BRAZIL on Feb 22, 2008. Male patient, child 7 years of age, weighting 32.19 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: condition aggravated, diffuse axonal injury, gait disturbance, hypotonia, intervertebral disc disorder, muscle spasticity, oxygen saturation decreased, pyramidal tract syndrome. Naglazyme dosage: 1.5 ML;QM;INTH;15 MG;X1;IV. Patient recovered.

Naglazyme Side Effects Report #5946395-9
Naglazyme side effect was reported by a Physician from COLOMBIA on Oct 23, 2008. Male patient, child 4 years of age, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: adenoidectomy, myringotomy, oxygen saturation decreased, tachypnoea, tonsillectomy. Naglazyme dosage: 10 MG;QW;IVDRP : 15 MG;QW;IVDRP. During the same period patient was treated with CETRIZIN, CEFALEXIN, OXYGEN. Patient was hospitalized. Patient recovered.

Naglazyme Side Effects Report #5413007-2
Naglazyme side effect was reported by a Health Professional from COLOMBIA on July 25, 2007. Male patient, child 3 years of age, weighting 24.25 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: alpha haemolytic streptococcal infection, cardiac failure congestive, culture positive, oxygen saturation decreased, pneumonia , pulmonary hypertension , respiratory distress, sleep study abnormal. Naglazyme dosage: 10 MG; QW; IV. During the same period patient was treated with BETA, BRONCHODILATOR, OXYGEN, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Naglazyme Side Effects Report #5383875-1
Naglazyme side effect was reported by a Health Professional from UNITED STATES on Apr 27, 2007. Male patient, 25 years of age, weighting 47.84 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: agitation, blood pressure diastolic increased, heart rate increased, infusion related reaction, malaise, oxygen saturation decreased, pallor, refusal of treatment by relative. Naglazyme dosage: 1 MG/MKG; QW; IV. Patient recovered.


Naglazyme Side Effects Report #5614707-1
Naglazyme side effect was reported by a Physician from PORTUGAL on Jan 16, 2008. Male patient, 14 years of age, weighting 94.80 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, body temperature increased, cyanosis, dyspnoea, haemorrhage, infusion related reaction, oxygen saturation decreased, pharyngeal oedema, rash . Naglazyme dosage: QW IV ; 43 MG 1X IV. Patient recovered.

Naglazyme Side Effects Report #5682171-2
Naglazyme side effect was reported by a Physician from PORTUGAL on Mar 10, 2008. Male patient, 14 years of age, weighting 94.80 lb, was diagnosed with mucopolysaccharidosis vi and was treated with Naglazyme. After drug was administered, patient experienced the following side effects: blood pressure increased, body temperature increased, cyanosis, dyspnoea, oxygen saturation decreased, rash , tachycardia, tremor. Naglazyme dosage: QW;IV; 43 MG;QW;IV. During the same period patient was treated with CLEMASTINE FUMARATE. Patient recovered.